SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS.
Identifieur interne : 001896 ( PubMed/Curation ); précédent : 001895; suivant : 001897SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS.
Auteurs : G Y Oudit [Canada] ; Z. Kassiri ; C. Jiang ; P P Liu ; S M Poutanen ; J M Penninger ; J. ButanySource :
- European journal of clinical investigation [ 1365-2362 ] ; 2009.
Descripteurs français
- KwdFr :
- Activation virale, Animaux, Autopsie, Humains, Immunohistochimie, Maladies cardiovasculaires (), Maladies cardiovasculaires (virologie), Myocarde (anatomopathologie), Mâle, Peptidyl-Dipeptidase A (génétique), Peptidyl-Dipeptidase A (métabolisme), Régulation négative, Souris, Virus du SRAS (génétique), Virus du SRAS (métabolisme).
- MESH :
- anatomopathologie : Myocarde.
- génétique : Peptidyl-Dipeptidase A, Virus du SRAS.
- métabolisme : Peptidyl-Dipeptidase A, Virus du SRAS.
- virologie : Maladies cardiovasculaires.
- Activation virale, Animaux, Autopsie, Humains, Immunohistochimie, Maladies cardiovasculaires, Mâle, Régulation négative, Souris.
English descriptors
- KwdEn :
- Animals, Autopsy, Cardiovascular Diseases (prevention & control), Cardiovascular Diseases (virology), Down-Regulation, Humans, Immunohistochemistry, Male, Mice, Myocardium (pathology), Peptidyl-Dipeptidase A (genetics), Peptidyl-Dipeptidase A (metabolism), SARS Virus (genetics), SARS Virus (metabolism), Virus Activation.
- MESH :
- chemical , genetics : Peptidyl-Dipeptidase A.
- chemical , metabolism : Peptidyl-Dipeptidase A.
- genetics : SARS Virus.
- metabolism : SARS Virus.
- pathology : Myocardium.
- prevention & control : Cardiovascular Diseases.
- virology : Cardiovascular Diseases.
- Animals, Autopsy, Down-Regulation, Humans, Immunohistochemistry, Male, Mice, Virus Activation.
Abstract
Angiotensin converting enzyme 2 (ACE2), a monocarboxylase that degrades angiotensin II to angiotensin 1-7, is also the functional receptor for severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) and is highly expressed in the lungs and heart. Patients with SARS also suffered from cardiac disease including arrhythmias, sudden cardiac death, and systolic and diastolic dysfunction.
DOI: 10.1111/j.1365-2362.2009.02153.x
PubMed: 19453650
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001896
Links to Exploration step
pubmed:19453650Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS.</title><author><name sortKey="Oudit, G Y" sort="Oudit, G Y" uniqKey="Oudit G" first="G Y" last="Oudit">G Y Oudit</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, University of Alberta, Edmonton, Alberta, Canada. gavin.oudit@ualberta.ca</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Medicine, University of Alberta, Edmonton, Alberta</wicri:regionArea></affiliation></author><author><name sortKey="Kassiri, Z" sort="Kassiri, Z" uniqKey="Kassiri Z" first="Z" last="Kassiri">Z. Kassiri</name></author><author><name sortKey="Jiang, C" sort="Jiang, C" uniqKey="Jiang C" first="C" last="Jiang">C. Jiang</name></author><author><name sortKey="Liu, P P" sort="Liu, P P" uniqKey="Liu P" first="P P" last="Liu">P P Liu</name></author><author><name sortKey="Poutanen, S M" sort="Poutanen, S M" uniqKey="Poutanen S" first="S M" last="Poutanen">S M Poutanen</name></author><author><name sortKey="Penninger, J M" sort="Penninger, J M" uniqKey="Penninger J" first="J M" last="Penninger">J M Penninger</name></author><author><name sortKey="Butany, J" sort="Butany, J" uniqKey="Butany J" first="J" last="Butany">J. Butany</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2009">2009</date><idno type="RBID">pubmed:19453650</idno><idno type="pmid">19453650</idno><idno type="doi">10.1111/j.1365-2362.2009.02153.x</idno><idno type="wicri:Area/PubMed/Corpus">001896</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001896</idno><idno type="wicri:Area/PubMed/Curation">001896</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001896</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS.</title><author><name sortKey="Oudit, G Y" sort="Oudit, G Y" uniqKey="Oudit G" first="G Y" last="Oudit">G Y Oudit</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, University of Alberta, Edmonton, Alberta, Canada. gavin.oudit@ualberta.ca</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Medicine, University of Alberta, Edmonton, Alberta</wicri:regionArea></affiliation></author><author><name sortKey="Kassiri, Z" sort="Kassiri, Z" uniqKey="Kassiri Z" first="Z" last="Kassiri">Z. Kassiri</name></author><author><name sortKey="Jiang, C" sort="Jiang, C" uniqKey="Jiang C" first="C" last="Jiang">C. Jiang</name></author><author><name sortKey="Liu, P P" sort="Liu, P P" uniqKey="Liu P" first="P P" last="Liu">P P Liu</name></author><author><name sortKey="Poutanen, S M" sort="Poutanen, S M" uniqKey="Poutanen S" first="S M" last="Poutanen">S M Poutanen</name></author><author><name sortKey="Penninger, J M" sort="Penninger, J M" uniqKey="Penninger J" first="J M" last="Penninger">J M Penninger</name></author><author><name sortKey="Butany, J" sort="Butany, J" uniqKey="Butany J" first="J" last="Butany">J. Butany</name></author></analytic><series><title level="j">European journal of clinical investigation</title><idno type="eISSN">1365-2362</idno><imprint><date when="2009" type="published">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Autopsy</term><term>Cardiovascular Diseases (prevention & control)</term><term>Cardiovascular Diseases (virology)</term><term>Down-Regulation</term><term>Humans</term><term>Immunohistochemistry</term><term>Male</term><term>Mice</term><term>Myocardium (pathology)</term><term>Peptidyl-Dipeptidase A (genetics)</term><term>Peptidyl-Dipeptidase A (metabolism)</term><term>SARS Virus (genetics)</term><term>SARS Virus (metabolism)</term><term>Virus Activation</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Activation virale</term><term>Animaux</term><term>Autopsie</term><term>Humains</term><term>Immunohistochimie</term><term>Maladies cardiovasculaires ()</term><term>Maladies cardiovasculaires (virologie)</term><term>Myocarde (anatomopathologie)</term><term>Mâle</term><term>Peptidyl-Dipeptidase A (génétique)</term><term>Peptidyl-Dipeptidase A (métabolisme)</term><term>Régulation négative</term><term>Souris</term><term>Virus du SRAS (génétique)</term><term>Virus du SRAS (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Peptidyl-Dipeptidase A</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Peptidyl-Dipeptidase A</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Myocarde</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Peptidyl-Dipeptidase A</term><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Peptidyl-Dipeptidase A</term><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Myocardium</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Cardiovascular Diseases</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Maladies cardiovasculaires</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Cardiovascular Diseases</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Autopsy</term><term>Down-Regulation</term><term>Humans</term><term>Immunohistochemistry</term><term>Male</term><term>Mice</term><term>Virus Activation</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Activation virale</term><term>Animaux</term><term>Autopsie</term><term>Humains</term><term>Immunohistochimie</term><term>Maladies cardiovasculaires</term><term>Mâle</term><term>Régulation négative</term><term>Souris</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Angiotensin converting enzyme 2 (ACE2), a monocarboxylase that degrades angiotensin II to angiotensin 1-7, is also the functional receptor for severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) and is highly expressed in the lungs and heart. Patients with SARS also suffered from cardiac disease including arrhythmias, sudden cardiac death, and systolic and diastolic dysfunction.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">19453650</PMID><DateCompleted><Year>2010</Year><Month>02</Month><Day>22</Day></DateCompleted><DateRevised><Year>2020</Year><Month>04</Month><Day>18</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1365-2362</ISSN><JournalIssue CitedMedium="Internet"><Volume>39</Volume><Issue>7</Issue><PubDate><Year>2009</Year><Month>Jul</Month></PubDate></JournalIssue><Title>European journal of clinical investigation</Title><ISOAbbreviation>Eur. J. Clin. Invest.</ISOAbbreviation></Journal><ArticleTitle>SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS.</ArticleTitle><Pagination><MedlinePgn>618-25</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1111/j.1365-2362.2009.02153.x</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Angiotensin converting enzyme 2 (ACE2), a monocarboxylase that degrades angiotensin II to angiotensin 1-7, is also the functional receptor for severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) and is highly expressed in the lungs and heart. Patients with SARS also suffered from cardiac disease including arrhythmias, sudden cardiac death, and systolic and diastolic dysfunction.</AbstractText><AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">We studied mice infected with the human strain of the SARS-CoV and encephalomyocarditis virus and examined ACE2 mRNA and protein expression. Autopsy heart samples from patients who succumbed to the SARS crisis in Toronto (Canada) were used to investigate the impact of SARS on myocardial structure, inflammation and ACE2 protein expression.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Pulmonary infection with the human SARS-CoV in mice led to an ACE2-dependent myocardial infection with a marked decrease in ACE2 expression confirming a critical role of ACE2 in mediating SARS-CoV infection in the heart. The SARS-CoV viral RNA was detected in 35% (7/20) of autopsied human heart samples obtained from patients who succumbed to the SARS crisis during the Toronto SARS outbreak. Macrophage-specific staining showed a marked increase in macrophage infiltration with evidence of myocardial damage in patients who had SARS-CoV in their hearts. The presence of SARS-CoV in the heart was also associated with marked reductions in ACE2 protein expression.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Our data show that SARS-CoV can mediate myocardial inflammation and damage associated with down-regulation of myocardial ACE2 system, which may be responsible for the myocardial dysfunction and adverse cardiac outcomes in patients with SARS.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Oudit</LastName><ForeName>G Y</ForeName><Initials>GY</Initials><AffiliationInfo><Affiliation>Department of Medicine, University of Alberta, Edmonton, Alberta, Canada. gavin.oudit@ualberta.ca</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kassiri</LastName><ForeName>Z</ForeName><Initials>Z</Initials></Author><Author ValidYN="Y"><LastName>Jiang</LastName><ForeName>C</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>P P</ForeName><Initials>PP</Initials></Author><Author ValidYN="Y"><LastName>Poutanen</LastName><ForeName>S M</ForeName><Initials>SM</Initials></Author><Author ValidYN="Y"><LastName>Penninger</LastName><ForeName>J M</ForeName><Initials>JM</Initials></Author><Author ValidYN="Y"><LastName>Butany</LastName><ForeName>J</ForeName><Initials>J</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2009</Year><Month>05</Month><Day>06</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Eur J Clin Invest</MedlineTA><NlmUniqueID>0245331</NlmUniqueID><ISSNLinking>0014-2972</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>EC 3.4.15.1</RegistryNumber><NameOfSubstance UI="D007703">Peptidyl-Dipeptidase A</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 3.4.17.-</RegistryNumber><NameOfSubstance UI="C413524">angiotensin converting enzyme 2</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001344" MajorTopicYN="N">Autopsy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002318" MajorTopicYN="N">Cardiovascular Diseases</DescriptorName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName><QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015536" MajorTopicYN="N">Down-Regulation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007150" MajorTopicYN="N">Immunohistochemistry</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D051379" MajorTopicYN="N">Mice</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009206" MajorTopicYN="N">Myocardium</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007703" MajorTopicYN="N">Peptidyl-Dipeptidase A</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D045473" MajorTopicYN="N">SARS Virus</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014775" MajorTopicYN="N">Virus Activation</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2009</Year><Month>5</Month><Day>21</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2009</Year><Month>5</Month><Day>21</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2010</Year><Month>2</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">19453650</ArticleId><ArticleId IdType="pii">ECI2153</ArticleId><ArticleId IdType="doi">10.1111/j.1365-2362.2009.02153.x</ArticleId><ArticleId IdType="pmc">PMC7163766</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>JAMA. 2003 Jun 4;289(21):2801-9</Citation><ArticleIdList><ArticleId IdType="pubmed">12734147</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Circulation. 2006 Feb 14;113(6):876-90</Citation><ArticleIdList><ArticleId IdType="pubmed">16476862</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Circ Res. 2005 Aug 19;97(4):380-90</Citation><ArticleIdList><ArticleId IdType="pubmed">16037568</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Nature. 2002 Jun 20;417(6891):822-8</Citation><ArticleIdList><ArticleId IdType="pubmed">12075344</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Virus Res. 2008 Apr;133(1):13-9</Citation><ArticleIdList><ArticleId IdType="pubmed">17374415</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>N Engl J Med. 2003 Dec 18;349(25):2468-9</Citation><ArticleIdList><ArticleId IdType="pubmed">14681520</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Circulation. 2003 Oct 14;108(15):1798-803</Citation><ArticleIdList><ArticleId IdType="pubmed">14504188</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Nat Med. 2005 Aug;11(8):875-9</Citation><ArticleIdList><ArticleId IdType="pubmed">16007097</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>N Engl J Med. 2003 Dec 18;349(25):2431-41</Citation><ArticleIdList><ArticleId IdType="pubmed">14681510</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Trends Pharmacol Sci. 2004 Jun;25(6):291-4</Citation><ArticleIdList><ArticleId IdType="pubmed">15165741</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Infect Dis. 2005 Jan 15;191(2):193-7</Citation><ArticleIdList><ArticleId IdType="pubmed">15609228</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Virol. 2007 Aug;81(16):8692-706</Citation><ArticleIdList><ArticleId IdType="pubmed">17537853</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Mod Pathol. 2005 Jan;18(1):1-10</Citation><ArticleIdList><ArticleId IdType="pubmed">15272286</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Circulation. 2004 Jul 6;110(1):46-50</Citation><ArticleIdList><ArticleId IdType="pubmed">15210601</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Postgrad Med J. 2006 Feb;82(964):140-4</Citation><ArticleIdList><ArticleId IdType="pubmed">16461478</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Clin Invest. 1992 Nov;90(5):2022-30</Citation><ArticleIdList><ArticleId IdType="pubmed">1331179</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Nature. 2003 Nov 27;426(6965):450-4</Citation><ArticleIdList><ArticleId IdType="pubmed">14647384</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>N Engl J Med. 2003 May 15;348(20):1995-2005</Citation><ArticleIdList><ArticleId IdType="pubmed">12671061</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Cardiovasc Res. 2007 Jul 1;75(1):29-39</Citation><ArticleIdList><ArticleId IdType="pubmed">17499227</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14194-9</Citation><ArticleIdList><ArticleId IdType="pubmed">16963558</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Virology. 2006 Sep 30;353(2):474-81</Citation><ArticleIdList><ArticleId IdType="pubmed">16860835</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Circ Res. 2000 Sep 1;87(5):E1-9</Citation><ArticleIdList><ArticleId IdType="pubmed">10969042</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Nature. 2005 Jul 7;436(7047):112-6</Citation><ArticleIdList><ArticleId IdType="pubmed">16001071</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7809-14</Citation><ArticleIdList><ArticleId IdType="pubmed">18490652</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>JAMA. 2003 Jul 16;290(3):367-73</Citation><ArticleIdList><ArticleId IdType="pubmed">12865378</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Am J Pathol. 2006 Jun;168(6):1808-20</Citation><ArticleIdList><ArticleId IdType="pubmed">16723697</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Trends Cardiovasc Med. 2003 Apr;13(3):93-101</Citation><ArticleIdList><ArticleId IdType="pubmed">12691672</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Hypertension. 2006 Apr;47(4):718-26</Citation><ArticleIdList><ArticleId IdType="pubmed">16505206</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Biol Chem. 2008 Feb 8;283(6):3272-80</Citation><ArticleIdList><ArticleId IdType="pubmed">18055455</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Virus Res. 2008 Sep;136(1-2):8-15</Citation><ArticleIdList><ArticleId IdType="pubmed">18554741</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Emerg Infect Dis. 2004 Jan;10(1):20-4</Citation><ArticleIdList><ArticleId IdType="pubmed">15078592</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Am J Pathol. 2007 Aug;171(2):438-51</Citation><ArticleIdList><ArticleId IdType="pubmed">17600118</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Nat Med. 2004 Dec;10(12 Suppl):S88-97</Citation><ArticleIdList><ArticleId IdType="pubmed">15577937</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/PubMed/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001896 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 001896 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= PubMed
|étape= Curation
|type= RBID
|clé= pubmed:19453650
|texte= SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i -Sk "pubmed:19453650" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd \
| NlmPubMed2Wicri -a SrasV1
| This area was generated with Dilib version V0.6.33. |  |