SrasV1, PubMed, Curation, bibRecord, 000F22

Molecular pathology of emerging coronavirus infections.

Identifieur interne : 000F22 ( PubMed/Curation ); précédent : 000F21; suivant : 000F23

Molecular pathology of emerging coronavirus infections.

Auteurs : Lisa E. Gralinski [États-Unis] ; Ralph S. Baric

Source :

The Journal of pathology [ 1096-9896 ] ; 2015.

RBID : pubmed:25270030

Descripteurs français

KwdFr :
- Anatomopathologie moléculaire (), Animaux, Antiviraux (usage thérapeutique), Appareil respiratoire (), Appareil respiratoire (anatomopathologie), Appareil respiratoire (immunologie), Appareil respiratoire (virologie), Biopsie, Coronavirus (), Coronavirus (immunologie), Coronavirus (isolement et purification), Coronavirus (pathogénicité), Coronavirus du syndrome respiratoire du Moyen-Orient (isolement et purification), Coronavirus du syndrome respiratoire du Moyen-Orient (pathogénicité), Facteurs de risque, Humains, Immunité innée, Infections à coronavirus (anatomopathologie), Infections à coronavirus (immunologie), Infections à coronavirus (traitement médicamenteux), Infections à coronavirus (virologie), Interactions hôte-pathogène, Maladies transmissibles émergentes, Syndrome respiratoire aigu sévère (anatomopathologie), Syndrome respiratoire aigu sévère (traitement médicamenteux), Syndrome respiratoire aigu sévère (virologie), Valeur prédictive des tests, Virologie (), Virulence, Virus du SRAS (isolement et purification), Virus du SRAS (pathogénicité).
MESH :
- anatomopathologie : Appareil respiratoire, Infections à coronavirus, Syndrome respiratoire aigu sévère.
- immunologie : Appareil respiratoire, Coronavirus, Infections à coronavirus.
- isolement et purification : Coronavirus, Coronavirus du syndrome respiratoire du Moyen-Orient, Virus du SRAS.
- pathogénicité : Coronavirus, Coronavirus du syndrome respiratoire du Moyen-Orient, Virus du SRAS.
- traitement médicamenteux : Infections à coronavirus, Syndrome respiratoire aigu sévère.
- usage thérapeutique : Antiviraux.
- virologie : Appareil respiratoire, Infections à coronavirus, Syndrome respiratoire aigu sévère.
- Anatomopathologie moléculaire, Animaux, Appareil respiratoire, Biopsie, Coronavirus, Facteurs de risque, Humains, Immunité innée, Interactions hôte-pathogène, Maladies transmissibles émergentes, Valeur prédictive des tests, Virologie, Virulence.

English descriptors

KwdEn :
- Animals, Antiviral Agents (therapeutic use), Biopsy, Communicable Diseases, Emerging, Coronavirus (drug effects), Coronavirus (immunology), Coronavirus (isolation & purification), Coronavirus (pathogenicity), Coronavirus Infections (drug therapy), Coronavirus Infections (immunology), Coronavirus Infections (pathology), Coronavirus Infections (virology), Host-Pathogen Interactions, Humans, Immunity, Innate, Middle East Respiratory Syndrome Coronavirus (isolation & purification), Middle East Respiratory Syndrome Coronavirus (pathogenicity), Pathology, Molecular (methods), Predictive Value of Tests, Respiratory System (drug effects), Respiratory System (immunology), Respiratory System (pathology), Respiratory System (virology), Risk Factors, SARS Virus (isolation & purification), SARS Virus (pathogenicity), Severe Acute Respiratory Syndrome (drug therapy), Severe Acute Respiratory Syndrome (pathology), Severe Acute Respiratory Syndrome (virology), Virology (methods), Virulence.
MESH :
- chemical , therapeutic use : Antiviral Agents.
- drug effects : Coronavirus, Respiratory System.
- drug therapy : Coronavirus Infections, Severe Acute Respiratory Syndrome.
- immunology : Coronavirus, Coronavirus Infections, Respiratory System.
- isolation & purification : Coronavirus, Middle East Respiratory Syndrome Coronavirus, SARS Virus.
- methods : Pathology, Molecular, Virology.
- pathogenicity : Coronavirus, Middle East Respiratory Syndrome Coronavirus, SARS Virus.
- pathology : Coronavirus Infections, Respiratory System, Severe Acute Respiratory Syndrome.
- virology : Coronavirus Infections, Respiratory System, Severe Acute Respiratory Syndrome.
- Animals, Biopsy, Communicable Diseases, Emerging, Host-Pathogen Interactions, Humans, Immunity, Innate, Predictive Value of Tests, Risk Factors, Virulence.

Abstract

Respiratory viruses can cause a wide spectrum of pulmonary diseases, ranging from mild, upper respiratory tract infections to severe and life-threatening lower respiratory tract infections, including the development of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Viral clearance and subsequent recovery from infection require activation of an effective host immune response; however, many immune effector cells may also cause injury to host tissues. Severe acute respiratory syndrome (SARS) coronavirus and Middle East respiratory syndrome (MERS) coronavirus cause severe infection of the lower respiratory tract, with 10% and 35% overall mortality rates, respectively; however, >50% mortality rates are seen in the aged and immunosuppressed populations. While these viruses are susceptible to interferon treatment in vitro, they both encode numerous genes that allow for successful evasion of the host immune system until after high virus titres have been achieved. In this review, we discuss the importance of the innate immune response and the development of lung pathology following human coronavirus infection.

DOI: 10.1002/path.4454
PubMed: 25270030

Links toward previous steps (curation, corpus...)

to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000F22

Links to Exploration step

pubmed:25270030

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Molecular pathology of emerging coronavirus infections.</title>
<author><name sortKey="Gralinski, Lisa E" sort="Gralinski, Lisa E" uniqKey="Gralinski L" first="Lisa E" last="Gralinski">Lisa E. Gralinski</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of North Carolina, Chapel Hill, NC</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Baric, Ralph S" sort="Baric, Ralph S" uniqKey="Baric R" first="Ralph S" last="Baric">Ralph S. Baric</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2015">2015</date>
<idno type="RBID">pubmed:25270030</idno>
<idno type="pmid">25270030</idno>
<idno type="doi">10.1002/path.4454</idno>
<idno type="wicri:Area/PubMed/Corpus">000F22</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000F22</idno>
<idno type="wicri:Area/PubMed/Curation">000F22</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000F22</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Molecular pathology of emerging coronavirus infections.</title>
<author><name sortKey="Gralinski, Lisa E" sort="Gralinski, Lisa E" uniqKey="Gralinski L" first="Lisa E" last="Gralinski">Lisa E. Gralinski</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, University of North Carolina, Chapel Hill, NC</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Baric, Ralph S" sort="Baric, Ralph S" uniqKey="Baric R" first="Ralph S" last="Baric">Ralph S. Baric</name>
</author>
</analytic>
<series><title level="j">The Journal of pathology</title>
<idno type="eISSN">1096-9896</idno>
<imprint><date when="2015" type="published">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Antiviral Agents (therapeutic use)</term>
<term>Biopsy</term>
<term>Communicable Diseases, Emerging</term>
<term>Coronavirus (drug effects)</term>
<term>Coronavirus (immunology)</term>
<term>Coronavirus (isolation & purification)</term>
<term>Coronavirus (pathogenicity)</term>
<term>Coronavirus Infections (drug therapy)</term>
<term>Coronavirus Infections (immunology)</term>
<term>Coronavirus Infections (pathology)</term>
<term>Coronavirus Infections (virology)</term>
<term>Host-Pathogen Interactions</term>
<term>Humans</term>
<term>Immunity, Innate</term>
<term>Middle East Respiratory Syndrome Coronavirus (isolation & purification)</term>
<term>Middle East Respiratory Syndrome Coronavirus (pathogenicity)</term>
<term>Pathology, Molecular (methods)</term>
<term>Predictive Value of Tests</term>
<term>Respiratory System (drug effects)</term>
<term>Respiratory System (immunology)</term>
<term>Respiratory System (pathology)</term>
<term>Respiratory System (virology)</term>
<term>Risk Factors</term>
<term>SARS Virus (isolation & purification)</term>
<term>SARS Virus (pathogenicity)</term>
<term>Severe Acute Respiratory Syndrome (drug therapy)</term>
<term>Severe Acute Respiratory Syndrome (pathology)</term>
<term>Severe Acute Respiratory Syndrome (virology)</term>
<term>Virology (methods)</term>
<term>Virulence</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Anatomopathologie moléculaire ()</term>
<term>Animaux</term>
<term>Antiviraux (usage thérapeutique)</term>
<term>Appareil respiratoire ()</term>
<term>Appareil respiratoire (anatomopathologie)</term>
<term>Appareil respiratoire (immunologie)</term>
<term>Appareil respiratoire (virologie)</term>
<term>Biopsie</term>
<term>Coronavirus ()</term>
<term>Coronavirus (immunologie)</term>
<term>Coronavirus (isolement et purification)</term>
<term>Coronavirus (pathogénicité)</term>
<term>Coronavirus du syndrome respiratoire du Moyen-Orient (isolement et purification)</term>
<term>Coronavirus du syndrome respiratoire du Moyen-Orient (pathogénicité)</term>
<term>Facteurs de risque</term>
<term>Humains</term>
<term>Immunité innée</term>
<term>Infections à coronavirus (anatomopathologie)</term>
<term>Infections à coronavirus (immunologie)</term>
<term>Infections à coronavirus (traitement médicamenteux)</term>
<term>Infections à coronavirus (virologie)</term>
<term>Interactions hôte-pathogène</term>
<term>Maladies transmissibles émergentes</term>
<term>Syndrome respiratoire aigu sévère (anatomopathologie)</term>
<term>Syndrome respiratoire aigu sévère (traitement médicamenteux)</term>
<term>Syndrome respiratoire aigu sévère (virologie)</term>
<term>Valeur prédictive des tests</term>
<term>Virologie ()</term>
<term>Virulence</term>
<term>Virus du SRAS (isolement et purification)</term>
<term>Virus du SRAS (pathogénicité)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiviral Agents</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Appareil respiratoire</term>
<term>Infections à coronavirus</term>
<term>Syndrome respiratoire aigu sévère</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Coronavirus</term>
<term>Respiratory System</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Coronavirus Infections</term>
<term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Appareil respiratoire</term>
<term>Coronavirus</term>
<term>Infections à coronavirus</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Coronavirus</term>
<term>Coronavirus Infections</term>
<term>Respiratory System</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Coronavirus</term>
<term>Middle East Respiratory Syndrome Coronavirus</term>
<term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Coronavirus</term>
<term>Coronavirus du syndrome respiratoire du Moyen-Orient</term>
<term>Virus du SRAS</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Pathology, Molecular</term>
<term>Virology</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Coronavirus</term>
<term>Middle East Respiratory Syndrome Coronavirus</term>
<term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Coronavirus</term>
<term>Coronavirus du syndrome respiratoire du Moyen-Orient</term>
<term>Virus du SRAS</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Respiratory System</term>
<term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à coronavirus</term>
<term>Syndrome respiratoire aigu sévère</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antiviraux</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Appareil respiratoire</term>
<term>Infections à coronavirus</term>
<term>Syndrome respiratoire aigu sévère</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Respiratory System</term>
<term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Biopsy</term>
<term>Communicable Diseases, Emerging</term>
<term>Host-Pathogen Interactions</term>
<term>Humans</term>
<term>Immunity, Innate</term>
<term>Predictive Value of Tests</term>
<term>Risk Factors</term>
<term>Virulence</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Anatomopathologie moléculaire</term>
<term>Animaux</term>
<term>Appareil respiratoire</term>
<term>Biopsie</term>
<term>Coronavirus</term>
<term>Facteurs de risque</term>
<term>Humains</term>
<term>Immunité innée</term>
<term>Interactions hôte-pathogène</term>
<term>Maladies transmissibles émergentes</term>
<term>Valeur prédictive des tests</term>
<term>Virologie</term>
<term>Virulence</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Respiratory viruses can cause a wide spectrum of pulmonary diseases, ranging from mild, upper respiratory tract infections to severe and life-threatening lower respiratory tract infections, including the development of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Viral clearance and subsequent recovery from infection require activation of an effective host immune response; however, many immune effector cells may also cause injury to host tissues. Severe acute respiratory syndrome (SARS) coronavirus and Middle East respiratory syndrome (MERS) coronavirus cause severe infection of the lower respiratory tract, with 10% and 35% overall mortality rates, respectively; however, >50% mortality rates are seen in the aged and immunosuppressed populations. While these viruses are susceptible to interferon treatment in vitro, they both encode numerous genes that allow for successful evasion of the host immune system until after high virus titres have been achieved. In this review, we discuss the importance of the innate immune response and the development of lung pathology following human coronavirus infection.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">25270030</PMID>
<DateCompleted><Year>2015</Year>
<Month>02</Month>
<Day>13</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>04</Month>
<Day>04</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1096-9896</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>235</Volume>
<Issue>2</Issue>
<PubDate><Year>2015</Year>
<Month>Jan</Month>
</PubDate>
</JournalIssue>
<Title>The Journal of pathology</Title>
<ISOAbbreviation>J. Pathol.</ISOAbbreviation>
</Journal>
<ArticleTitle>Molecular pathology of emerging coronavirus infections.</ArticleTitle>
<Pagination><MedlinePgn>185-95</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1002/path.4454</ELocationID>
<Abstract><AbstractText>Respiratory viruses can cause a wide spectrum of pulmonary diseases, ranging from mild, upper respiratory tract infections to severe and life-threatening lower respiratory tract infections, including the development of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Viral clearance and subsequent recovery from infection require activation of an effective host immune response; however, many immune effector cells may also cause injury to host tissues. Severe acute respiratory syndrome (SARS) coronavirus and Middle East respiratory syndrome (MERS) coronavirus cause severe infection of the lower respiratory tract, with 10% and 35% overall mortality rates, respectively; however, >50% mortality rates are seen in the aged and immunosuppressed populations. While these viruses are susceptible to interferon treatment in vitro, they both encode numerous genes that allow for successful evasion of the host immune system until after high virus titres have been achieved. In this review, we discuss the importance of the innate immune response and the development of lung pathology following human coronavirus infection.</AbstractText>
<CopyrightInformation>© 2014 The Authors. The Journal of Pathology published by John Wiley & Sons Ltd on behalf of Pathological Society of Great Britain and Ireland.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Gralinski</LastName>
<ForeName>Lisa E</ForeName>
<Initials>LE</Initials>
<AffiliationInfo><Affiliation>Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Baric</LastName>
<ForeName>Ralph S</ForeName>
<Initials>RS</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><GrantID>HHSN272200800060C</GrantID>
<Acronym>AI</Acronym>
<Agency>NIAID NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>U19 AI100625</GrantID>
<Acronym>AI</Acronym>
<Agency>NIAID NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>U19 AI109761</GrantID>
<Acronym>AI</Acronym>
<Agency>NIAID NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>U19AI109761</GrantID>
<Acronym>AI</Acronym>
<Agency>NIAID NIH HHS</Agency>
<Country>United States</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType>
<PublicationType UI="D016454">Review</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>J Pathol</MedlineTA>
<NlmUniqueID>0204634</NlmUniqueID>
<ISSNLinking>0022-3417</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000998">Antiviral Agents</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000998" MajorTopicYN="N">Antiviral Agents</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001706" MajorTopicYN="N">Biopsy</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D021821" MajorTopicYN="Y">Communicable Diseases, Emerging</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017934" MajorTopicYN="N">Coronavirus</DescriptorName>
<QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
<QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName>
<QualifierName UI="Q000472" MajorTopicYN="Y">pathogenicity</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D054884" MajorTopicYN="N">Host-Pathogen Interactions</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007113" MajorTopicYN="N">Immunity, Innate</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D065207" MajorTopicYN="N">Middle East Respiratory Syndrome Coronavirus</DescriptorName>
<QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName>
<QualifierName UI="Q000472" MajorTopicYN="N">pathogenicity</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D057089" MajorTopicYN="N">Pathology, Molecular</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011237" MajorTopicYN="N">Predictive Value of Tests</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012137" MajorTopicYN="N">Respiratory System</DescriptorName>
<QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012307" MajorTopicYN="N">Risk Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D045473" MajorTopicYN="N">SARS Virus</DescriptorName>
<QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName>
<QualifierName UI="Q000472" MajorTopicYN="N">pathogenicity</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D045169" MajorTopicYN="N">Severe Acute Respiratory Syndrome</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014773" MajorTopicYN="N">Virology</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014774" MajorTopicYN="N">Virulence</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">ARDS</Keyword>
<Keyword MajorTopicYN="N">MERS-CoV</Keyword>
<Keyword MajorTopicYN="N">SARS-CoV</Keyword>
<Keyword MajorTopicYN="N">acute lung injury</Keyword>
<Keyword MajorTopicYN="N">acute respiratory distress syndrome</Keyword>
<Keyword MajorTopicYN="N">coronavirus</Keyword>
<Keyword MajorTopicYN="N">type II pneumocytes</Keyword>
</KeywordList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2014</Year>
<Month>09</Month>
<Day>18</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2014</Year>
<Month>09</Month>
<Day>25</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2014</Year>
<Month>10</Month>
<Day>2</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2014</Year>
<Month>10</Month>
<Day>2</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2015</Year>
<Month>2</Month>
<Day>14</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">25270030</ArticleId>
<ArticleId IdType="doi">10.1002/path.4454</ArticleId>
<ArticleId IdType="pmc">PMC4267971</ArticleId>
<ArticleId IdType="mid">NIHMS631789</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>J Interferon Cytokine Res. 2006 May;26(5):309-17</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16689659</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2012 Dec;86(23):12816-25</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22993147</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Chin Med J (Engl). 2003 Jul;116(7):968-71</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12890363</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Aerosol Med Pulm Drug Deliv. 2010 Aug;23(4):243-52</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20073554</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Immunol Invest. 1993 Mar;22(2):95-103</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8505072</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Mol Biol. 2006 Dec 15;364(5):964-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17054987</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Med. 2005 Aug;2(8):e240</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16104827</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Med. 2006 Feb;3(2):e27</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16379499</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2003 Apr 15;36(8):985-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12684910</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cytokine Growth Factor Rev. 2014 Oct;25(5):525-31</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25081316</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Respir Med. 2011 Jul;105(7):959-71</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21356587</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>MBio. 2013;4(4). pii: e00271-13. doi: 10.1128/mBio.00271-13</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23919993</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2003 May 15;348(20):1967-76</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12690091</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Microbiol. 2006 Jun;44(6):2063-71</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16757599</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2007 Apr;81(8):4012-20</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17267506</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2014 Jan;88(2):913-24</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24198408</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Thorax. 2010 Apr;65(4):334-40</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20388759</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2007 Sep;81(18):9812-24</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17596301</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2004 Jun;78(11):5642-50</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15140961</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2005 Sep 27;102(39):14040-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16169905</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2008 Dec;4(12):e1000240</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19079579</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2009 Mar;83(5):2368-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19091867</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virol J. 2013;10:359</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24364985</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Rev Clin Esp. 2014 Dec;214(9):499-504</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24958321</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2008 Aug;82(15):7721-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18463152</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nephrology (Carlton). 2009 Aug;14(5):462-70</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19674315</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Pathol. 2015 Jan;235(2):175-84</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25294366</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2003 May 24;361(9371):1767-72</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12781535</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2010 Apr;6(4):e1000849</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20386712</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Exp Immunol. 2004 Apr;136(1):95-103</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15030519</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Virol. 2010 May;48(1):27-30</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20233673</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 2004 Dec 5;330(1):8-15</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15527829</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Pathol. 2004 Jun;203(2):631-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15141377</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Infect Disord Drug Targets. 2014;14(1):37-43</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25019238</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2011 Oct;7(10):e1002315</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22028656</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2013 Jun 29;381(9885):2265-72</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23727167</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2009 Sep;15(9):1377-84</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19788804</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2005 Jan;79(2):884-95</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15613317</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Thromb Haemost. 2008 Mar;99(3):494-501</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18327397</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2012 Nov 8;367(19):1814-20</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23075143</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2013 Jun 27;368(26):2487-94</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23718156</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2012 Dec;86(24):13334-49</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23015710</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Gen Virol. 2012 Sep;93(Pt 9):1924-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22718567</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Respir Res. 2009;10:61</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19575792</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2005 Oct 28;310(5748):676-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16195424</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2005 May 31;102(22):7988-93</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15897467</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Thromb Haemost. 2004 Sep;92(3):529-40</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15351849</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Histopathology. 2004 Aug;45(2):119-24</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15279629</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2004 Oct;78(20):11401-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15452262</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2013 Jun;87(11):6081-90</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23427150</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2005 Jul 7;436(7047):112-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16001071</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Am Thorac Soc. 2012 Jul;9(3):96-101</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22802281</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2011;6(7):e21958</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21755013</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2011 May;85(9):4234-45</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21325418</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2005 May;79(9):5833-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15827197</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Med. 2004 Mar;10(3):290-3</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14981511</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2009 Jul;83(13):6689-705</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19369340</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Med Virol. 1984;13(2):179-92</Citation>
<ArticleIdList><ArticleId IdType="pubmed">6319590</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2003 Oct 30;425(6961):915</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14586458</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Crit Care. 1998;2(1):29-34</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11056707</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Hum Pathol. 2003 Aug;34(8):743-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14506633</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 2014 Apr;454-455:197-205</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24725946</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Rev Immunol. 2013 Jan;13(1):46-57</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23237964</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>MBio. 2013;4(5):e00650-13</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24023385</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Braz J Infect Dis. 2009 Jun;13(3):226-31</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20191202</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2008 Feb;82(4):1899-907</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18077725</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Respirology. 2003 Nov;8 Suppl:S6-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15018126</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2003 Jul 26;362(9380):293-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12892961</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2005 Dec;79(24):15511-24</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16306622</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2014 Apr;88(8):4251-64</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24478444</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Exp Med. 2008 Jul 7;205(7):1601-10</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18591409</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Formos Med Assoc. 2005 Feb;104(2):75-81</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15765160</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2014 Nov 1;59(9):1225-33</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24829216</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Pathol. 2013 Jan;229(2):176-85</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23096265</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2008 May;4(5):e1000054</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18451981</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16598-603</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24062443</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2005 Feb;79(3):1595-604</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15650185</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Pathol. 2004 Feb;202(2):157-63</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14743497</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2007 Aug 10;3(8):e112</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17696609</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2014 Aug;10(8):e1004250</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25144235</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Adv Exp Med Biol. 1998;440:635-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9782339</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>JAMA. 2003 Jun 4;289(21):2801-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12734147</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 1988 Jun;85(12):4526-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">3380803</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2009 Oct;5(10):e1000636</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19851468</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2014 Aug;20(8):1339-42</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25075761</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Gen Virol. 2014 Apr;95(Pt 4):874-82</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24443473</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2004 Oct;78(20):11416-21</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15452265</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Opin Virol. 2012 Jun;2(3):264-75</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22572391</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2007 Jan;81(2):548-57</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17108024</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virus Res. 2008 Apr;133(1):101-12</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17451827</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 1992 Jun 4;357(6377):420-2</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1350662</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Med Virol. 2005 Mar;75(3):455-62</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15648064</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2013 Mar 14;495(7440):251-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23486063</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2013 Nov 28;503(7477):535-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24172901</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Crit Care Clin. 2011 Jul;27(3):459-68</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21742211</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Pathol. 2003 Jul;200(3):282-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12845623</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>MBio. 2014;5(3):e01174-14</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24846384</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Dis. 2012 Dec 1;206(11):1685-94</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22829640</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1997 Jan;71(1):800-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8985420</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2012 Jan;86(2):884-97</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22072787</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Immunol. 2004 Sep 15;173(6):4030-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15356152</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Med. 2006 May;3(5):e149</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16605302</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Br J Haematol. 2005 May;129(3):307-21</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15842654</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2008 Feb;82(4):1819-26</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18057240</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Gen Virol. 1982 Jun;60(Pt 2):307-14</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7108490</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2003 Oct 10;302(5643):276-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12958366</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2003 Oct 1;37(7):929-32</Citation>
<ArticleIdList><ArticleId IdType="pubmed">13130404</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2007 Aug;81(16):8692-706</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17537853</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2005 Jan;79(1):503-11</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15596843</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Biol. 2008 Sep 16;6(9):e226</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18798692</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2014 Oct;88(19):11297-303</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25031349</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Med. 2004 Apr;10(4):368-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15034574</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Respir Res. 2001;2(1):33-46</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11686863</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Opin Pharmacol. 2006 Jun;6(3):271-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16581295</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet Infect Dis. 2013 Oct;13(10):859-66</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23933067</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Chest Med. 2006 Dec;27(4):705-24; abstract x</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17085257</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Med. 2005 Aug;11(8):875-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16007097</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Pediatrics. 2004 Jan;113(1 Pt 1):e7-14</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14702488</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2003 May 15;423(6937):240</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12748632</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2014 Aug;20(8):1319-22</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25075637</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2003 May 24;361(9371):1773-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12781536</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2010 Nov;84(21):11297-309</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20702617</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Respir Res. 2001;2(6):353-64</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11737935</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Protein Cell. 2013 Dec;4(12):951-61</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24318862</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2007 Jan;3(1):e5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17222058</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2003 May 15;348(20):1953-66</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12690092</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2007 Jan;81(2):813-21</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17079315</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Immunol. 2006 Nov 15;177(10):7233-41</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17082641</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell. 1996 Feb 9;84(3):431-42</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8608597</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mod Pathol. 2005 Jan;18(1):1-10</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15272286</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4970-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24599590</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virus Res. 2014 Dec 19;194:124-37</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25093995</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2013 May;87(9):5300-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23449793</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Gen Virol. 2013 Aug;94(Pt 8):1749-60</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23620378</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Thorax. 2004 May;59(5):414-20</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15115870</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 2008 Feb 8;283(6):3272-80</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18055455</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2010 Nov 18;468(7322):452-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21085181</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2006 Mar 1;42(5):634-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16447108</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2010 Feb;6(2):e1000756</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20140198</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biochim Biophys Acta. 2005 Aug 1;1751(1):2-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16054014</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2013 Jun;87(12):6551-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23576515</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2004 Jul;10(7):1293-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15324552</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Pathol. 2007 Apr;170(4):1136-47</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17392154</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2011 Jan;85(1):217-30</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20980507</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Influenza Other Respir Viruses. 2013 Nov;7(6):1040-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23462106</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>MBio. 2014;5(1). pii: e01062-13. doi: 10.1128/mBio.01062-13</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24549846</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Med. 2006 May;3(5):e194</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16608385</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2004 Apr;78(7):3572-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15016880</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/PubMed/Curation

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000F22 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 000F22 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    SrasV1
   |flux=    PubMed
   |étape=   Curation
   |type=    RBID
   |clé=     pubmed:25270030
   |texte=   Molecular pathology of emerging coronavirus infections.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i   -Sk "pubmed:25270030" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd   \
       | NlmPubMed2Wicri -a SrasV1

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 28 14:49:16 2020. Site generation: Sat Mar 27 22:06:49 2021

	Serveur d'exploration SRAS
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration SRAS

Molecular pathology of emerging coronavirus infections.

Molecular pathology of emerging coronavirus infections.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki