SrasV1, PubMed, Curation, bibRecord, 000E86

Coronavirus MHV-A59 infects the lung and causes severe pneumonia in C57BL/6 mice.

Identifieur interne : 000E86 ( PubMed/Curation ); précédent : 000E85; suivant : 000E87

Coronavirus MHV-A59 infects the lung and causes severe pneumonia in C57BL/6 mice.

Auteurs : Zhangsheng Yang [République populaire de Chine] ; Jun Du ; Gang Chen ; Jie Zhao ; Xuanming Yang ; Lishan Su ; Genhong Cheng ; Hong Tang

Source :

Virologica Sinica [ 1995-820X ] ; 2014.

RBID : pubmed:25547683

Descripteurs français

KwdFr :
- Animaux, Cytokines (génétique), Cytokines (immunologie), Femelle, Humains, Infections à coronavirus (génétique), Infections à coronavirus (immunologie), Infections à coronavirus (virologie), Modèles animaux de maladie humaine, Mâle, Pneumopathie infectieuse (génétique), Pneumopathie infectieuse (immunologie), Pneumopathie infectieuse (virologie), Poumon (immunologie), Poumon (virologie), Souris, Souris de lignée C57BL, Virulence, Virus de l'hépatite murine (pathogénicité), Virus de l'hépatite murine (physiologie).
MESH :
- génétique : Cytokines, Infections à coronavirus, Pneumopathie infectieuse.
- immunologie : Cytokines, Infections à coronavirus, Pneumopathie infectieuse, Poumon.
- pathogénicité : Virus de l'hépatite murine.
- physiologie : Virus de l'hépatite murine.
- virologie : Infections à coronavirus, Pneumopathie infectieuse, Poumon.
- Animaux, Femelle, Humains, Modèles animaux de maladie humaine, Mâle, Souris, Souris de lignée C57BL, Virulence.

English descriptors

KwdEn :
- Animals, Coronavirus Infections (genetics), Coronavirus Infections (immunology), Coronavirus Infections (virology), Cytokines (genetics), Cytokines (immunology), Disease Models, Animal, Female, Humans, Lung (immunology), Lung (virology), Male, Mice, Mice, Inbred C57BL, Murine hepatitis virus (pathogenicity), Murine hepatitis virus (physiology), Pneumonia (genetics), Pneumonia (immunology), Pneumonia (virology), Virulence.
MESH :
- chemical , genetics : Cytokines.
- genetics : Coronavirus Infections, Pneumonia.
- immunology : Coronavirus Infections, Cytokines, Lung, Pneumonia.
- pathogenicity : Murine hepatitis virus.
- physiology : Murine hepatitis virus.
- virology : Coronavirus Infections, Lung, Pneumonia.
- Animals, Disease Models, Animal, Female, Humans, Male, Mice, Mice, Inbred C57BL, Virulence.

Abstract

It remains challenging to develop animal models of lung infection and severe pneumonia by severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome cornavirus (MERS-CoV) without high level of containment. This inevitably hinders understanding of virushost interaction and development of appropriate countermeasures. Here we report that intranasal inoculation of sublethal doses of murine coronavirus mouse hepatitis virus A-59 (MHV-A59), a hepatic and neuronal tropic coronavirus, can induce acute pneumonia and severe lung injuries in C57BL/6 mice. Inflammatory leukocyte infiltrations, hemorrhages and fibrosis of alveolar walls can be observed 2-11 days after MHV-A59 infection. This pathological manifestation is associated with dramatical elevation of tissue IP-10 and IFN-γ and moderate increase of TNF-α and IL-1β, but inability of anti-viral type I interferon response. These results suggest that intranasal infection of MHV-A59 would serve as a surrogate mouse model of acute respiratory distress syndrome by SARS-CoV and MERS-CoV infections.

DOI: 10.1007/s12250-014-3530-y
PubMed: 25547683

Links toward previous steps (curation, corpus...)

to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000E86

Links to Exploration step

pubmed:25547683

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Coronavirus MHV-A59 infects the lung and causes severe pneumonia in C57BL/6 mice.</title>
<author><name sortKey="Yang, Zhangsheng" sort="Yang, Zhangsheng" uniqKey="Yang Z" first="Zhangsheng" last="Yang">Zhangsheng Yang</name>
<affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Infection and Immunity (CASKLII), Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Chaoyang District, Beijing, 100101, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Key Laboratory of Infection and Immunity (CASKLII), Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Chaoyang District, Beijing, 100101</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Du, Jun" sort="Du, Jun" uniqKey="Du J" first="Jun" last="Du">Jun Du</name>
</author>
<author><name sortKey="Chen, Gang" sort="Chen, Gang" uniqKey="Chen G" first="Gang" last="Chen">Gang Chen</name>
</author>
<author><name sortKey="Zhao, Jie" sort="Zhao, Jie" uniqKey="Zhao J" first="Jie" last="Zhao">Jie Zhao</name>
</author>
<author><name sortKey="Yang, Xuanming" sort="Yang, Xuanming" uniqKey="Yang X" first="Xuanming" last="Yang">Xuanming Yang</name>
</author>
<author><name sortKey="Su, Lishan" sort="Su, Lishan" uniqKey="Su L" first="Lishan" last="Su">Lishan Su</name>
</author>
<author><name sortKey="Cheng, Genhong" sort="Cheng, Genhong" uniqKey="Cheng G" first="Genhong" last="Cheng">Genhong Cheng</name>
</author>
<author><name sortKey="Tang, Hong" sort="Tang, Hong" uniqKey="Tang H" first="Hong" last="Tang">Hong Tang</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2014">2014</date>
<idno type="RBID">pubmed:25547683</idno>
<idno type="pmid">25547683</idno>
<idno type="doi">10.1007/s12250-014-3530-y</idno>
<idno type="wicri:Area/PubMed/Corpus">000E86</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000E86</idno>
<idno type="wicri:Area/PubMed/Curation">000E86</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000E86</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Coronavirus MHV-A59 infects the lung and causes severe pneumonia in C57BL/6 mice.</title>
<author><name sortKey="Yang, Zhangsheng" sort="Yang, Zhangsheng" uniqKey="Yang Z" first="Zhangsheng" last="Yang">Zhangsheng Yang</name>
<affiliation wicri:level="1"><nlm:affiliation>Key Laboratory of Infection and Immunity (CASKLII), Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Chaoyang District, Beijing, 100101, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Key Laboratory of Infection and Immunity (CASKLII), Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Chaoyang District, Beijing, 100101</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Du, Jun" sort="Du, Jun" uniqKey="Du J" first="Jun" last="Du">Jun Du</name>
</author>
<author><name sortKey="Chen, Gang" sort="Chen, Gang" uniqKey="Chen G" first="Gang" last="Chen">Gang Chen</name>
</author>
<author><name sortKey="Zhao, Jie" sort="Zhao, Jie" uniqKey="Zhao J" first="Jie" last="Zhao">Jie Zhao</name>
</author>
<author><name sortKey="Yang, Xuanming" sort="Yang, Xuanming" uniqKey="Yang X" first="Xuanming" last="Yang">Xuanming Yang</name>
</author>
<author><name sortKey="Su, Lishan" sort="Su, Lishan" uniqKey="Su L" first="Lishan" last="Su">Lishan Su</name>
</author>
<author><name sortKey="Cheng, Genhong" sort="Cheng, Genhong" uniqKey="Cheng G" first="Genhong" last="Cheng">Genhong Cheng</name>
</author>
<author><name sortKey="Tang, Hong" sort="Tang, Hong" uniqKey="Tang H" first="Hong" last="Tang">Hong Tang</name>
</author>
</analytic>
<series><title level="j">Virologica Sinica</title>
<idno type="eISSN">1995-820X</idno>
<imprint><date when="2014" type="published">2014</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Coronavirus Infections (genetics)</term>
<term>Coronavirus Infections (immunology)</term>
<term>Coronavirus Infections (virology)</term>
<term>Cytokines (genetics)</term>
<term>Cytokines (immunology)</term>
<term>Disease Models, Animal</term>
<term>Female</term>
<term>Humans</term>
<term>Lung (immunology)</term>
<term>Lung (virology)</term>
<term>Male</term>
<term>Mice</term>
<term>Mice, Inbred C57BL</term>
<term>Murine hepatitis virus (pathogenicity)</term>
<term>Murine hepatitis virus (physiology)</term>
<term>Pneumonia (genetics)</term>
<term>Pneumonia (immunology)</term>
<term>Pneumonia (virology)</term>
<term>Virulence</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Cytokines (génétique)</term>
<term>Cytokines (immunologie)</term>
<term>Femelle</term>
<term>Humains</term>
<term>Infections à coronavirus (génétique)</term>
<term>Infections à coronavirus (immunologie)</term>
<term>Infections à coronavirus (virologie)</term>
<term>Modèles animaux de maladie humaine</term>
<term>Mâle</term>
<term>Pneumopathie infectieuse (génétique)</term>
<term>Pneumopathie infectieuse (immunologie)</term>
<term>Pneumopathie infectieuse (virologie)</term>
<term>Poumon (immunologie)</term>
<term>Poumon (virologie)</term>
<term>Souris</term>
<term>Souris de lignée C57BL</term>
<term>Virulence</term>
<term>Virus de l'hépatite murine (pathogénicité)</term>
<term>Virus de l'hépatite murine (physiologie)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Cytokines</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Coronavirus Infections</term>
<term>Pneumonia</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Cytokines</term>
<term>Infections à coronavirus</term>
<term>Pneumopathie infectieuse</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Cytokines</term>
<term>Infections à coronavirus</term>
<term>Pneumopathie infectieuse</term>
<term>Poumon</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Cytokines</term>
<term>Lung</term>
<term>Pneumonia</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Murine hepatitis virus</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Virus de l'hépatite murine</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Virus de l'hépatite murine</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Murine hepatitis virus</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections à coronavirus</term>
<term>Pneumopathie infectieuse</term>
<term>Poumon</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term>
<term>Lung</term>
<term>Pneumonia</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Disease Models, Animal</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Mice</term>
<term>Mice, Inbred C57BL</term>
<term>Virulence</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Femelle</term>
<term>Humains</term>
<term>Modèles animaux de maladie humaine</term>
<term>Mâle</term>
<term>Souris</term>
<term>Souris de lignée C57BL</term>
<term>Virulence</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">It remains challenging to develop animal models of lung infection and severe pneumonia by severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome cornavirus (MERS-CoV) without high level of containment. This inevitably hinders understanding of virushost interaction and development of appropriate countermeasures. Here we report that intranasal inoculation of sublethal doses of murine coronavirus mouse hepatitis virus A-59 (MHV-A59), a hepatic and neuronal tropic coronavirus, can induce acute pneumonia and severe lung injuries in C57BL/6 mice. Inflammatory leukocyte infiltrations, hemorrhages and fibrosis of alveolar walls can be observed 2-11 days after MHV-A59 infection. This pathological manifestation is associated with dramatical elevation of tissue IP-10 and IFN-γ and moderate increase of TNF-α and IL-1β, but inability of anti-viral type I interferon response. These results suggest that intranasal infection of MHV-A59 would serve as a surrogate mouse model of acute respiratory distress syndrome by SARS-CoV and MERS-CoV infections. </div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">25547683</PMID>
<DateCompleted><Year>2015</Year>
<Month>09</Month>
<Day>02</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>03</Month>
<Day>25</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1995-820X</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>29</Volume>
<Issue>6</Issue>
<PubDate><Year>2014</Year>
<Month>Dec</Month>
</PubDate>
</JournalIssue>
<Title>Virologica Sinica</Title>
<ISOAbbreviation>Virol Sin</ISOAbbreviation>
</Journal>
<ArticleTitle>Coronavirus MHV-A59 infects the lung and causes severe pneumonia in C57BL/6 mice.</ArticleTitle>
<Pagination><MedlinePgn>393-402</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1007/s12250-014-3530-y</ELocationID>
<Abstract><AbstractText>It remains challenging to develop animal models of lung infection and severe pneumonia by severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome cornavirus (MERS-CoV) without high level of containment. This inevitably hinders understanding of virushost interaction and development of appropriate countermeasures. Here we report that intranasal inoculation of sublethal doses of murine coronavirus mouse hepatitis virus A-59 (MHV-A59), a hepatic and neuronal tropic coronavirus, can induce acute pneumonia and severe lung injuries in C57BL/6 mice. Inflammatory leukocyte infiltrations, hemorrhages and fibrosis of alveolar walls can be observed 2-11 days after MHV-A59 infection. This pathological manifestation is associated with dramatical elevation of tissue IP-10 and IFN-γ and moderate increase of TNF-α and IL-1β, but inability of anti-viral type I interferon response. These results suggest that intranasal infection of MHV-A59 would serve as a surrogate mouse model of acute respiratory distress syndrome by SARS-CoV and MERS-CoV infections. </AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Yang</LastName>
<ForeName>Zhangsheng</ForeName>
<Initials>Z</Initials>
<AffiliationInfo><Affiliation>Key Laboratory of Infection and Immunity (CASKLII), Institute of Biophysics, Chinese Academy of Sciences, 15 Datun Road, Chaoyang District, Beijing, 100101, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Du</LastName>
<ForeName>Jun</ForeName>
<Initials>J</Initials>
</Author>
<Author ValidYN="Y"><LastName>Chen</LastName>
<ForeName>Gang</ForeName>
<Initials>G</Initials>
</Author>
<Author ValidYN="Y"><LastName>Zhao</LastName>
<ForeName>Jie</ForeName>
<Initials>J</Initials>
</Author>
<Author ValidYN="Y"><LastName>Yang</LastName>
<ForeName>Xuanming</ForeName>
<Initials>X</Initials>
</Author>
<Author ValidYN="Y"><LastName>Su</LastName>
<ForeName>Lishan</ForeName>
<Initials>L</Initials>
</Author>
<Author ValidYN="Y"><LastName>Cheng</LastName>
<ForeName>Genhong</ForeName>
<Initials>G</Initials>
</Author>
<Author ValidYN="Y"><LastName>Tang</LastName>
<ForeName>Hong</ForeName>
<Initials>H</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2014</Year>
<Month>12</Month>
<Day>22</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>China</Country>
<MedlineTA>Virol Sin</MedlineTA>
<NlmUniqueID>101514185</NlmUniqueID>
<ISSNLinking>1995-820X</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D016207">Cytokines</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016207" MajorTopicYN="N">Cytokines</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004195" MajorTopicYN="N">Disease Models, Animal</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008168" MajorTopicYN="N">Lung</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D051379" MajorTopicYN="N">Mice</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008810" MajorTopicYN="N">Mice, Inbred C57BL</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006517" MajorTopicYN="N">Murine hepatitis virus</DescriptorName>
<QualifierName UI="Q000472" MajorTopicYN="N">pathogenicity</QualifierName>
<QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011014" MajorTopicYN="N">Pneumonia</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="Y">virology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014774" MajorTopicYN="N">Virulence</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2014</Year>
<Month>11</Month>
<Day>02</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2014</Year>
<Month>12</Month>
<Day>10</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2014</Year>
<Month>12</Month>
<Day>31</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2014</Year>
<Month>12</Month>
<Day>31</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2015</Year>
<Month>9</Month>
<Day>4</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">25547683</ArticleId>
<ArticleId IdType="doi">10.1007/s12250-014-3530-y</ArticleId>
<ArticleId IdType="pmc">PMC7090691</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>J Virol. 2010 Sep;84(18):9278-91</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20631137</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Immunol. 1998 Jan 1;160(1):444-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9552002</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cytokine Growth Factor Rev. 2002 Dec;13(6):441-54</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12401479</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Annu Rev Immunol. 1993;11:571-611</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8476573</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lab Anim Sci. 1986 Apr;36(2):130-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">3009966</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Med. 2007 Oct;13(10):1248-52</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17891146</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Am J Respir Crit Care Med. 2005 Apr 15;171(8):850-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15657466</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Neurology. 1984 May;34(5):597-603</Citation>
<ArticleIdList><ArticleId IdType="pubmed">6324031</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2003 May 15;348(20):1967-76</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12690091</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Immunol. 1998 Apr 15;160(8):3958-64</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9558103</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Mol Biol. 2003 Aug 29;331(5):991-1004</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12927536</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2011 Feb 18;6(2):e17192</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21364999</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 1990 Aug;177(2):634-45</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2164727</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 1995 Apr 1;208(1):1-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11831690</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2005 Sep 27;102(39):14040-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16169905</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2012 Nov 8;367 (19):1814-20</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23075143</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 2009 Dec 20;395(2):210-22</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19853271</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1993 Aug;67(8):4504-12</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8392595</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Dis. 2014 May 1;209(9):1331-42</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24065148</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2005 Oct 28;310(5748):676-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16195424</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Rev Microbiol. 2013 Dec;11(12):836-48</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24217413</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>BMC Immunol. 2005 Jan 18;6:2</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15655079</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Arch Virol. 1984;81(1-2):103-12</Citation>
<ArticleIdList><ArticleId IdType="pubmed">6331343</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Philos Trans R Soc Lond B Biol Sci. 2004 Jul 29;359(1447):1081-2</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15306393</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 2014 Apr;454-455:197-205</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24725946</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2010 Dec;84(23 ):12419-28</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20861244</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2003 Apr 19;361(9366):1319-25</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12711465</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Viral Immunol. 2001;14(1):1-18</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11270593</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Gen Virol. 2013 Dec;94(Pt 12):2679-90</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24077366</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Adv Exp Med Biol. 2006;581:373-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17037562</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Gen Virol. 2014 Feb;95(Pt 2):408-12</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24197535</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Exp Med. 1987 Jan 1;165(1):64-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">3794607</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Pathol. 2006 Nov;210(3):288-97</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17031779</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2013 Jul 02;8(7):e69127</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23844250</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1995 Oct;69(10):6541-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7666556</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2013 Apr 18;368(16):1560-2</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23550601</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2006 Nov;80(21):10382-94</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17041219</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2013 Nov 28;503(7477):535-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24172901</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Med Virol. 2005 Feb;75(2):185-94</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15602737</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Med. 2013 Aug;19(8):952</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23921729</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect. 2012 Dec;65(6):477-89</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23072791</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2012 Jan;86(2):884-97</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22072787</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Antivir Ther. 2005;10 (2):263-75</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15865221</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Exp Med. 1996 Sep 1;184(3):963-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9064356</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lymphokine Cytokine Res. 1991 Oct;10(5):353-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1768738</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2014 Aug 21;10(8):e1004250</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25144235</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2003 May 24;361(9371):1773-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12781536</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Chest. 1995 Nov;108(5):1303-14</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7587434</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2007 Jan;3(1):e5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17222058</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Annu Rev Immunol. 2007;25:443-72</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17243893</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2003 May 15;348(20):1953-66</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12690092</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Immunol. 1999 Feb 1;162(3):1641-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9973424</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2007 Jan;81(2):813-21</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17079315</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Microbiol Mol Biol Rev. 2005 Dec;69(4):635-64</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16339739</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4970-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24599590</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2004 Sep;78(18):10156-65</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15331748</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Immunity. 2002 Sep;17(3):251-63</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12354379</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Int Immunopharmacol. 2011 Oct;11(10):1591-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21635973</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Chest. 1995 Apr;107(4):1062-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">7705118</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Res. 2008 Nov;18(11):1105-13</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18957937</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2008 May 27;105(21):7528-33</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18490660</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/PubMed/Curation

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000E86 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd -nk 000E86 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    SrasV1
   |flux=    PubMed
   |étape=   Curation
   |type=    RBID
   |clé=     pubmed:25547683
   |texte=   Coronavirus MHV-A59 infects the lung and causes severe pneumonia in C57BL/6 mice.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Curation/RBID.i   -Sk "pubmed:25547683" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Curation/biblio.hfd   \
       | NlmPubMed2Wicri -a SrasV1

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 28 14:49:16 2020. Site generation: Sat Mar 27 22:06:49 2021

	Serveur d'exploration SRAS
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration SRAS

Coronavirus MHV-A59 infects the lung and causes severe pneumonia in C57BL/6 mice.

Coronavirus MHV-A59 infects the lung and causes severe pneumonia in C57BL/6 mice.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki