Novel Bat Alphacoronaviruses in Southern China Support Chinese Horseshoe Bats as an Important Reservoir for Potential Novel Coronaviruses.
Identifieur interne : 000907 ( PubMed/Curation ); précédent : 000906; suivant : 000908Novel Bat Alphacoronaviruses in Southern China Support Chinese Horseshoe Bats as an Important Reservoir for Potential Novel Coronaviruses.
Auteurs : Susanna K P. Lau [République populaire de Chine] ; Antonio C P. Wong [République populaire de Chine] ; Libao Zhang [République populaire de Chine] ; Hayes K H. Luk [République populaire de Chine] ; Jamie S L. Kwok [République populaire de Chine] ; Syed S. Ahmed [République populaire de Chine] ; Jian-Piao Cai [République populaire de Chine] ; Pyrear S H. Zhao [République populaire de Chine] ; Jade L L. Teng [République populaire de Chine] ; Stephen K W. Tsui [République populaire de Chine] ; Kwok-Yung Yuen [République populaire de Chine] ; Patrick C Y. Woo [République populaire de Chine]Source :
- Viruses [ 1999-4915 ] ; 2019.
Abstract
While bats are increasingly recognized as a source of coronavirus epidemics, the diversity and emergence potential of bat coronaviruses remains to be fully understood. Among 1779 bat samples collected in China, diverse coronaviruses were detected in 32 samples from five different bat species by RT-PCR. Two novel alphacoronaviruses, Rhinolophus sinicus bat coronavirus HKU32 (Rs-BatCoV HKU32) and Tylonycteris robustula bat coronavirus HKU33 (Tr-BatCoV HKU33), were discovered from Chinese horseshoe bats in Hong Kong and greater bamboo bats in Guizhou Province, respectively. Genome analyses showed that Rs-BatCoV HKU32 is closely related to BatCoV HKU10 and related viruses from diverse bat families, whereas Tr-BatCoV HKU33 is closely related to BtNv-AlphaCoV and similar viruses exclusively from bats of Vespertilionidae family. The close relatedness of Rs-BatCoV HKU32 to BatCoV HKU10 which was also detected in Pomona roundleaf bats from the same country park suggests that these viruses may have the tendency of infecting genetically distant bat populations of close geographical proximity with subsequent genetic divergence. Moreover, the presence of SARSr-CoV ORF7a-like protein in Rs-BatCoV HKU32 suggests a common evolutionary origin of this accessory protein with SARS-CoV, also from Chinese horseshoe bats, an apparent reservoir for coronavirus epidemics. The emergence potential of Rs-BatCoV HKU32 should be explored.
DOI: 10.3390/v11050423
PubMed: 31067830
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Novel Bat Alphacoronaviruses in Southern China Support Chinese Horseshoe Bats as an Important Reservoir for Potential Novel Coronaviruses.</title><author><name sortKey="Lau, Susanna K P" sort="Lau, Susanna K P" uniqKey="Lau S" first="Susanna K P" last="Lau">Susanna K P. Lau</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. skplau@hku.hk.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea></affiliation></author><author><name sortKey="Wong, Antonio C P" sort="Wong, Antonio C P" uniqKey="Wong A" first="Antonio C P" last="Wong">Antonio C P. Wong</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. antonwcp@connect.hku.hk.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea></affiliation></author><author><name sortKey="Zhang, Libao" sort="Zhang, Libao" uniqKey="Zhang L" first="Libao" last="Zhang">Libao Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Guangdong Key Laboratory of Animal Conservation and Resource Utilization, Guangdong Public Laboratory of Wild Animal Conservation and Utilization, Guangdong Institute of Applied Biological Resources, Guangzhou 510000, China. zhanglb@giabr.gd.cn.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Guangdong Key Laboratory of Animal Conservation and Resource Utilization, Guangdong Public Laboratory of Wild Animal Conservation and Utilization, Guangdong Institute of Applied Biological Resources, Guangzhou 510000</wicri:regionArea></affiliation></author><author><name sortKey="Luk, Hayes K H" sort="Luk, Hayes K H" uniqKey="Luk H" first="Hayes K H" last="Luk">Hayes K H. 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Zhao</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. pyrear@126.com.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea></affiliation></author><author><name sortKey="Teng, Jade L L" sort="Teng, Jade L L" uniqKey="Teng J" first="Jade L L" last="Teng">Jade L L. Teng</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. llteng@hku.hk.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea></affiliation></author><author><name sortKey="Tsui, Stephen K W" sort="Tsui, Stephen K W" uniqKey="Tsui S" first="Stephen K W" last="Tsui">Stephen K W. Tsui</name><affiliation wicri:level="1"><nlm:affiliation>School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, China. kwtsui@cuhk.edu.hk.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong</wicri:regionArea></affiliation></author><author><name sortKey="Yuen, Kwok Yung" sort="Yuen, Kwok Yung" uniqKey="Yuen K" first="Kwok-Yung" last="Yuen">Kwok-Yung Yuen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. kyyuen@hku.hk.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea></affiliation></author><author><name sortKey="Woo, Patrick C Y" sort="Woo, Patrick C Y" uniqKey="Woo P" first="Patrick C Y" last="Woo">Patrick C Y. Woo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. pcywoo@hku.hk.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2019">2019</date><idno type="RBID">pubmed:31067830</idno><idno type="pmid">31067830</idno><idno type="doi">10.3390/v11050423</idno><idno type="wicri:Area/PubMed/Corpus">000907</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000907</idno><idno type="wicri:Area/PubMed/Curation">000907</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000907</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Novel Bat Alphacoronaviruses in Southern China Support Chinese Horseshoe Bats as an Important Reservoir for Potential Novel Coronaviruses.</title><author><name sortKey="Lau, Susanna K P" sort="Lau, Susanna K P" uniqKey="Lau S" first="Susanna K P" last="Lau">Susanna K P. Lau</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. skplau@hku.hk.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea></affiliation></author><author><name sortKey="Wong, Antonio C P" sort="Wong, Antonio C P" uniqKey="Wong A" first="Antonio C P" last="Wong">Antonio C P. Wong</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. antonwcp@connect.hku.hk.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea></affiliation></author><author><name sortKey="Zhang, Libao" sort="Zhang, Libao" uniqKey="Zhang L" first="Libao" last="Zhang">Libao Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Guangdong Key Laboratory of Animal Conservation and Resource Utilization, Guangdong Public Laboratory of Wild Animal Conservation and Utilization, Guangdong Institute of Applied Biological Resources, Guangzhou 510000, China. zhanglb@giabr.gd.cn.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Guangdong Key Laboratory of Animal Conservation and Resource Utilization, Guangdong Public Laboratory of Wild Animal Conservation and Utilization, Guangdong Institute of Applied Biological Resources, Guangzhou 510000</wicri:regionArea></affiliation></author><author><name sortKey="Luk, Hayes K H" sort="Luk, Hayes K H" uniqKey="Luk H" first="Hayes K H" last="Luk">Hayes K H. Luk</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. hkhluk@hku.hk.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea></affiliation></author><author><name sortKey="Kwok, Jamie S L" sort="Kwok, Jamie S L" uniqKey="Kwok J" first="Jamie S L" last="Kwok">Jamie S L. Kwok</name><affiliation wicri:level="1"><nlm:affiliation>School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, China. jamie_slk@link.cuhk.edu.hk.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong</wicri:regionArea></affiliation></author><author><name sortKey="Ahmed, Syed S" sort="Ahmed, Syed S" uniqKey="Ahmed S" first="Syed S" last="Ahmed">Syed S. Ahmed</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. shakeel87@gmail.com.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea></affiliation></author><author><name sortKey="Cai, Jian Piao" sort="Cai, Jian Piao" uniqKey="Cai J" first="Jian-Piao" last="Cai">Jian-Piao Cai</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. caijuice@hku.hk.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea></affiliation></author><author><name sortKey="Zhao, Pyrear S H" sort="Zhao, Pyrear S H" uniqKey="Zhao P" first="Pyrear S H" last="Zhao">Pyrear S H. Zhao</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. pyrear@126.com.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea></affiliation></author><author><name sortKey="Teng, Jade L L" sort="Teng, Jade L L" uniqKey="Teng J" first="Jade L L" last="Teng">Jade L L. Teng</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. llteng@hku.hk.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea></affiliation></author><author><name sortKey="Tsui, Stephen K W" sort="Tsui, Stephen K W" uniqKey="Tsui S" first="Stephen K W" last="Tsui">Stephen K W. Tsui</name><affiliation wicri:level="1"><nlm:affiliation>School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, China. kwtsui@cuhk.edu.hk.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong</wicri:regionArea></affiliation></author><author><name sortKey="Yuen, Kwok Yung" sort="Yuen, Kwok Yung" uniqKey="Yuen K" first="Kwok-Yung" last="Yuen">Kwok-Yung Yuen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. kyyuen@hku.hk.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea></affiliation></author><author><name sortKey="Woo, Patrick C Y" sort="Woo, Patrick C Y" uniqKey="Woo P" first="Patrick C Y" last="Woo">Patrick C Y. Woo</name><affiliation wicri:level="1"><nlm:affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. pcywoo@hku.hk.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong</wicri:regionArea></affiliation></author></analytic><series><title level="j">Viruses</title><idno type="eISSN">1999-4915</idno><imprint><date when="2019" type="published">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">While bats are increasingly recognized as a source of coronavirus epidemics, the diversity and emergence potential of bat coronaviruses remains to be fully understood. Among 1779 bat samples collected in China, diverse coronaviruses were detected in 32 samples from five different bat species by RT-PCR. Two novel alphacoronaviruses, <i>Rhinolophus sinicus</i> bat coronavirus HKU32 (Rs-BatCoV HKU32) and <i>Tylonycteris robustula</i> bat coronavirus HKU33 (Tr-BatCoV HKU33), were discovered from Chinese horseshoe bats in Hong Kong and greater bamboo bats in Guizhou Province, respectively. Genome analyses showed that Rs-BatCoV HKU32 is closely related to BatCoV HKU10 and related viruses from diverse bat families, whereas Tr-BatCoV HKU33 is closely related to BtNv-AlphaCoV and similar viruses exclusively from bats of <i>Vespertilionidae</i> family. The close relatedness of Rs-BatCoV HKU32 to BatCoV HKU10 which was also detected in Pomona roundleaf bats from the same country park suggests that these viruses may have the tendency of infecting genetically distant bat populations of close geographical proximity with subsequent genetic divergence. Moreover, the presence of SARSr-CoV ORF7a-like protein in Rs-BatCoV HKU32 suggests a common evolutionary origin of this accessory protein with SARS-CoV, also from Chinese horseshoe bats, an apparent reservoir for coronavirus epidemics. The emergence potential of Rs-BatCoV HKU32 should be explored.</div></front></TEI><pubmed><MedlineCitation Status="In-Data-Review" Owner="NLM"><PMID Version="1">31067830</PMID><DateRevised><Year>2020</Year><Month>02</Month><Day>25</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1999-4915</ISSN><JournalIssue CitedMedium="Internet"><Volume>11</Volume><Issue>5</Issue><PubDate><Year>2019</Year><Month>May</Month><Day>07</Day></PubDate></JournalIssue><Title>Viruses</Title><ISOAbbreviation>Viruses</ISOAbbreviation></Journal><ArticleTitle>Novel Bat Alphacoronaviruses in Southern China Support Chinese Horseshoe Bats as an Important Reservoir for Potential Novel Coronaviruses.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">E423</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.3390/v11050423</ELocationID><Abstract><AbstractText>While bats are increasingly recognized as a source of coronavirus epidemics, the diversity and emergence potential of bat coronaviruses remains to be fully understood. Among 1779 bat samples collected in China, diverse coronaviruses were detected in 32 samples from five different bat species by RT-PCR. Two novel alphacoronaviruses, <i>Rhinolophus sinicus</i> bat coronavirus HKU32 (Rs-BatCoV HKU32) and <i>Tylonycteris robustula</i> bat coronavirus HKU33 (Tr-BatCoV HKU33), were discovered from Chinese horseshoe bats in Hong Kong and greater bamboo bats in Guizhou Province, respectively. Genome analyses showed that Rs-BatCoV HKU32 is closely related to BatCoV HKU10 and related viruses from diverse bat families, whereas Tr-BatCoV HKU33 is closely related to BtNv-AlphaCoV and similar viruses exclusively from bats of <i>Vespertilionidae</i> family. The close relatedness of Rs-BatCoV HKU32 to BatCoV HKU10 which was also detected in Pomona roundleaf bats from the same country park suggests that these viruses may have the tendency of infecting genetically distant bat populations of close geographical proximity with subsequent genetic divergence. Moreover, the presence of SARSr-CoV ORF7a-like protein in Rs-BatCoV HKU32 suggests a common evolutionary origin of this accessory protein with SARS-CoV, also from Chinese horseshoe bats, an apparent reservoir for coronavirus epidemics. The emergence potential of Rs-BatCoV HKU32 should be explored.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Lau</LastName><ForeName>Susanna K P</ForeName><Initials>SKP</Initials><AffiliationInfo><Affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. skplau@hku.hk.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Pokfulam, Hong Kong, China. skplau@hku.hk.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Carol Yu Centre for Infection, The University of Hong Kong, Pokfulam, Hong Kong, China. skplau@hku.hk.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, The University of Hong Kong, Pokfulam, Hong Kong, China. skplau@hku.hk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wong</LastName><ForeName>Antonio C P</ForeName><Initials>ACP</Initials><AffiliationInfo><Affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. antonwcp@connect.hku.hk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Libao</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Guangdong Key Laboratory of Animal Conservation and Resource Utilization, Guangdong Public Laboratory of Wild Animal Conservation and Utilization, Guangdong Institute of Applied Biological Resources, Guangzhou 510000, China. zhanglb@giabr.gd.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Luk</LastName><ForeName>Hayes K H</ForeName><Initials>HKH</Initials><AffiliationInfo><Affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. hkhluk@hku.hk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kwok</LastName><ForeName>Jamie S L</ForeName><Initials>JSL</Initials><AffiliationInfo><Affiliation>School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, China. jamie_slk@link.cuhk.edu.hk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ahmed</LastName><ForeName>Syed S</ForeName><Initials>SS</Initials><AffiliationInfo><Affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. shakeel87@gmail.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cai</LastName><ForeName>Jian-Piao</ForeName><Initials>JP</Initials><AffiliationInfo><Affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. caijuice@hku.hk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhao</LastName><ForeName>Pyrear S H</ForeName><Initials>PSH</Initials><AffiliationInfo><Affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. pyrear@126.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Teng</LastName><ForeName>Jade L L</ForeName><Initials>JLL</Initials><AffiliationInfo><Affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. llteng@hku.hk.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Pokfulam, Hong Kong, China. llteng@hku.hk.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Carol Yu Centre for Infection, The University of Hong Kong, Pokfulam, Hong Kong, China. llteng@hku.hk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tsui</LastName><ForeName>Stephen K W</ForeName><Initials>SKW</Initials><AffiliationInfo><Affiliation>School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, China. kwtsui@cuhk.edu.hk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yuen</LastName><ForeName>Kwok-Yung</ForeName><Initials>KY</Initials><AffiliationInfo><Affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. kyyuen@hku.hk.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Pokfulam, Hong Kong, China. kyyuen@hku.hk.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Carol Yu Centre for Infection, The University of Hong Kong, Pokfulam, Hong Kong, China. kyyuen@hku.hk.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, The University of Hong Kong, Pokfulam, Hong Kong, China. kyyuen@hku.hk.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Woo</LastName><ForeName>Patrick C Y</ForeName><Initials>PCY</Initials><AffiliationInfo><Affiliation>Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China. pcywoo@hku.hk.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Pokfulam, Hong Kong, China. pcywoo@hku.hk.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Carol Yu Centre for Infection, The University of Hong Kong, Pokfulam, Hong Kong, China. pcywoo@hku.hk.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Collaborative Innovation Centre for Diagnosis and Treatment of Infectious Diseases, The University of Hong Kong, Pokfulam, Hong Kong, China. pcywoo@hku.hk.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>T11/707/15</GrantID><Agency>University Grants Committee</Agency><Country></Country></Grant><Grant><GrantID>201711159148</GrantID><Agency>University Research Committee, University of Hong Kong</Agency><Country></Country></Grant><Grant><GrantID>2017GDASCX-0107</GrantID><Agency>GDAS Special Project of Science and Technology Development</Agency><Country></Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2019</Year><Month>05</Month><Day>07</Day></ArticleDate></Article><MedlineJournalInfo><Country>Switzerland</Country><MedlineTA>Viruses</MedlineTA><NlmUniqueID>101509722</NlmUniqueID><ISSNLinking>1999-4915</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Alphacoronavirus</Keyword><Keyword MajorTopicYN="N">bat</Keyword><Keyword MajorTopicYN="N">coronavirus</Keyword><Keyword MajorTopicYN="N">discovery</Keyword><Keyword MajorTopicYN="N">epidemics</Keyword><Keyword MajorTopicYN="N">molecular</Keyword><Keyword MajorTopicYN="N">novel</Keyword><Keyword MajorTopicYN="N">species</Keyword></KeywordList><CoiStatement>The authors declare no conflict of interest.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2019</Year><Month>04</Month><Day>15</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2019</Year><Month>05</Month><Day>02</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2019</Year><Month>05</Month><Day>06</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2019</Year><Month>5</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2019</Year><Month>5</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2019</Year><Month>5</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">31067830</ArticleId><ArticleId IdType="pii">v11050423</ArticleId><ArticleId IdType="doi">10.3390/v11050423</ArticleId><ArticleId IdType="pmc">PMC6563315</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Lancet. 2003 Apr 19;361(9366):1319-25</Citation><ArticleIdList><ArticleId IdType="pubmed">12711465</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Med. 2004 Apr;10(4):368-73</Citation><ArticleIdList><ArticleId IdType="pubmed">15034574</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Top Microbiol Immunol. 2005;287:1-30</Citation><ArticleIdList><ArticleId IdType="pubmed">15609507</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2005 Jan;79(2):884-95</Citation><ArticleIdList><ArticleId IdType="pubmed">15613317</ArticleId></ArticleIdList></Reference><Reference><Citation>Structure. 2005 Jan;13(1):75-85</Citation><ArticleIdList><ArticleId IdType="pubmed">15642263</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2005 Sep 27;102(39):14040-5</Citation><ArticleIdList><ArticleId IdType="pubmed">16169905</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 2006 Jul 20;351(1):180-7</Citation><ArticleIdList><ArticleId IdType="pubmed">16647731</ArticleId></ArticleIdList></Reference><Reference><Citation>Adv Exp Med Biol. 2006;581:115-20</Citation><ArticleIdList><ArticleId IdType="pubmed">17037516</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2007 Feb;81(4):1574-85</Citation><ArticleIdList><ArticleId IdType="pubmed">17121802</ArticleId></ArticleIdList></Reference><Reference><Citation>Philos Trans R Soc Lond B Biol Sci. 2007 Jun 29;362(1482):1063-81</Citation><ArticleIdList><ArticleId IdType="pubmed">17327210</ArticleId></ArticleIdList></Reference><Reference><Citation>Virology. 2007 Oct 25;367(2):428-39</Citation><ArticleIdList><ArticleId IdType="pubmed">17617433</ArticleId></ArticleIdList></Reference><Reference><Citation>Emerg Infect Dis. 2009 Sep;15(9):1377-84</Citation><ArticleIdList><ArticleId IdType="pubmed">19788804</ArticleId></ArticleIdList></Reference><Reference><Citation>Syst Biol. 2010 May;59(3):307-21</Citation><ArticleIdList><ArticleId IdType="pubmed">20525638</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2012 Apr;86(7):3995-4008</Citation><ArticleIdList><ArticleId IdType="pubmed">22278237</ArticleId></ArticleIdList></Reference><Reference><Citation>J Mol Biol. 1990 Oct 5;215(3):403-10</Citation><ArticleIdList><ArticleId IdType="pubmed">2231712</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2012 May;86(10):5481-96</Citation><ArticleIdList><ArticleId IdType="pubmed">22398294</ArticleId></ArticleIdList></Reference><Reference><Citation>J Comput Biol. 2012 May;19(5):455-77</Citation><ArticleIdList><ArticleId IdType="pubmed">22506599</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2012 Nov;86(21):11906-18</Citation><ArticleIdList><ArticleId IdType="pubmed">22933277</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2012 Nov 8;367(19):1814-20</Citation><ArticleIdList><ArticleId IdType="pubmed">23075143</ArticleId></ArticleIdList></Reference><Reference><Citation>MBio. 2012 Nov 20;3(6):null</Citation><ArticleIdList><ArticleId IdType="pubmed">23170002</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2013 Aug;87(15):8638-50</Citation><ArticleIdList><ArticleId IdType="pubmed">23720729</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet Infect Dis. 2013 Oct;13(10):859-66</Citation><ArticleIdList><ArticleId IdType="pubmed">23933067</ArticleId></ArticleIdList></Reference><Reference><Citation>MBio. 2013 Oct 15;4(5):e00737-13</Citation><ArticleIdList><ArticleId IdType="pubmed">24129257</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet Infect Dis. 2014 Feb;14(2):140-5</Citation><ArticleIdList><ArticleId IdType="pubmed">24355866</ArticleId></ArticleIdList></Reference><Reference><Citation>Emerg Infect Dis. 2014 Jul;20(7):1260-2</Citation><ArticleIdList><ArticleId IdType="pubmed">24960574</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2014 Oct;88(19):11297-303</Citation><ArticleIdList><ArticleId IdType="pubmed">25031349</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12516-21</Citation><ArticleIdList><ArticleId IdType="pubmed">25114257</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Host Microbe. 2014 Sep 10;16(3):328-37</Citation><ArticleIdList><ArticleId IdType="pubmed">25211075</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2015 Mar;89(6):3076-92</Citation><ArticleIdList><ArticleId IdType="pubmed">25552712</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Microbiol Rev. 2015 Apr;28(2):465-522</Citation><ArticleIdList><ArticleId IdType="pubmed">25810418</ArticleId></ArticleIdList></Reference><Reference><Citation>Emerg Microbes Infect. 2012 Nov;1(11):e35</Citation><ArticleIdList><ArticleId IdType="pubmed">26038405</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2015 Dec;89(23):11858-70</Citation><ArticleIdList><ArticleId IdType="pubmed">26378164</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2017 Feb 14;91(5):</Citation><ArticleIdList><ArticleId IdType="pubmed">28077633</ArticleId></ArticleIdList></Reference><Reference><Citation>MBio. 2017 Apr 4;8(2):</Citation><ArticleIdList><ArticleId IdType="pubmed">28377531</ArticleId></ArticleIdList></Reference><Reference><Citation>Emerg Infect Dis. 2017 Sep;23(9):</Citation><ArticleIdList><ArticleId IdType="pubmed">28654418</ArticleId></ArticleIdList></Reference><Reference><Citation>Brief Bioinform. 2017 Sep 6;:null</Citation><ArticleIdList><ArticleId IdType="pubmed">28968734</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Mol Sci. 2017 Oct 16;18(10):null</Citation><ArticleIdList><ArticleId IdType="pubmed">29035289</ArticleId></ArticleIdList></Reference><Reference><Citation>Vet Microbiol. 2017 Nov;211:15-21</Citation><ArticleIdList><ArticleId IdType="pubmed">29102111</ArticleId></ArticleIdList></Reference><Reference><Citation>J Infect Dis. 2018 Jun 20;218(2):197-207</Citation><ArticleIdList><ArticleId IdType="pubmed">29346682</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2018 Apr;556(7700):255-258</Citation><ArticleIdList><ArticleId IdType="pubmed">29618817</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2018 Jun 13;92(13):</Citation><ArticleIdList><ArticleId IdType="pubmed">29669833</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2018 Jul 17;92(15):</Citation><ArticleIdList><ArticleId IdType="pubmed">29769348</ArticleId></ArticleIdList></Reference><Reference><Citation>Viruses. 2019 Feb 20;11(2):null</Citation><ArticleIdList><ArticleId IdType="pubmed">30791586</ArticleId></ArticleIdList></Reference><Reference><Citation>Adv Virus Res. 1997;48:1-100</Citation><ArticleIdList><ArticleId IdType="pubmed">9233431</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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