Molecular basis of COVID-19 relationships in different species: a one health perspective.
Identifieur interne : 000574 ( PubMed/Curation ); précédent : 000573; suivant : 000575Molecular basis of COVID-19 relationships in different species: a one health perspective.
Auteurs : Bruno Tilocca [Italie] ; Alessio Soggiu [Italie] ; Vincenzo Musella [Italie] ; Domenico Britti [Italie] ; Maurizio Sanguinetti [Italie] ; Andrea Urbani [Italie] ; Paola Roncada [Italie]Source :
- Microbes and infection [ 1769-714X ] ; 2020.
Abstract
Outside the Hubei province, China, the mild form of infection and the progressive recover of the COVID-19 patients suggest the intervention of "unconventional" biological mechanisms worthy of attention. Based on the high-homology between the Spike protein epitopes of taxonomically-related coronaviruses, we hypothesized that past contact with infected dogs shield humans against the circulating SARS-CoV-2. Elseways, the recurrent virus exposure over a short time-lapse might result in the Antibody Dependent Enhancement, triggering the violent immune reaction responsible for the severe clinical outcomes observed in the Hubei province. Nevertheless, further experimental studies are desired for a confidential evaluation of the postulated hypotheses.
DOI: 10.1016/j.micinf.2020.03.002
PubMed: 32194253
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Vito n1, 00168 Rome, Italy; Dipartimento Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario Gemelli IRCCS, Largo S. Vito n8, 00168 Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Basic Biotechnological Sciences, Intensivological and Perioperative Clinics, Università Cattolica del Sacro Cuore, Largo S. Vito n1, 00168 Rome, Italy; Dipartimento Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario Gemelli IRCCS, Largo S. Vito n8, 00168 Rome</wicri:regionArea></affiliation></author><author><name sortKey="Urbani, Andrea" sort="Urbani, Andrea" uniqKey="Urbani A" first="Andrea" last="Urbani">Andrea Urbani</name><affiliation wicri:level="1"><nlm:affiliation>Department of Basic Biotechnological Sciences, Intensivological and Perioperative Clinics, Università Cattolica del Sacro Cuore, Largo S. Vito n1, 00168 Rome, Italy; Dipartimento Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario Gemelli IRCCS, Largo S. Vito n8, 00168 Rome, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Basic Biotechnological Sciences, Intensivological and Perioperative Clinics, Università Cattolica del Sacro Cuore, Largo S. Vito n1, 00168 Rome, Italy; Dipartimento Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario Gemelli IRCCS, Largo S. Vito n8, 00168 Rome</wicri:regionArea></affiliation></author><author><name sortKey="Roncada, Paola" sort="Roncada, Paola" uniqKey="Roncada P" first="Paola" last="Roncada">Paola Roncada</name><affiliation wicri:level="1"><nlm:affiliation>Department of Health Science, University "Magna Græcia" of Catanzaro, Viale Europa, 88100 Catanzaro, Italy. Electronic address: roncada@unicz.it.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Health Science, University "Magna Græcia" of Catanzaro, Viale Europa, 88100 Catanzaro</wicri:regionArea></affiliation></author></analytic><series><title level="j">Microbes and infection</title><idno type="eISSN">1769-714X</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Outside the Hubei province, China, the mild form of infection and the progressive recover of the COVID-19 patients suggest the intervention of "unconventional" biological mechanisms worthy of attention. Based on the high-homology between the Spike protein epitopes of taxonomically-related coronaviruses, we hypothesized that past contact with infected dogs shield humans against the circulating SARS-CoV-2. Elseways, the recurrent virus exposure over a short time-lapse might result in the Antibody Dependent Enhancement, triggering the violent immune reaction responsible for the severe clinical outcomes observed in the Hubei province. Nevertheless, further experimental studies are desired for a confidential evaluation of the postulated hypotheses.</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32194253</PMID><DateRevised><Year>2020</Year><Month>04</Month><Day>01</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1769-714X</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2020</Year><Month>Mar</Month><Day>17</Day></PubDate></JournalIssue><Title>Microbes and infection</Title><ISOAbbreviation>Microbes Infect.</ISOAbbreviation></Journal><ArticleTitle>Molecular basis of COVID-19 relationships in different species: a one health perspective.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">S1286-4579(20)30048-4</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.micinf.2020.03.002</ELocationID><Abstract><AbstractText>Outside the Hubei province, China, the mild form of infection and the progressive recover of the COVID-19 patients suggest the intervention of "unconventional" biological mechanisms worthy of attention. Based on the high-homology between the Spike protein epitopes of taxonomically-related coronaviruses, we hypothesized that past contact with infected dogs shield humans against the circulating SARS-CoV-2. Elseways, the recurrent virus exposure over a short time-lapse might result in the Antibody Dependent Enhancement, triggering the violent immune reaction responsible for the severe clinical outcomes observed in the Hubei province. Nevertheless, further experimental studies are desired for a confidential evaluation of the postulated hypotheses.</AbstractText><CopyrightInformation>Copyright © 2020 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Tilocca</LastName><ForeName>Bruno</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Health Science, University "Magna Græcia" of Catanzaro, Viale Europa, 88100 Catanzaro, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Soggiu</LastName><ForeName>Alessio</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Veterinary Sciences, University of Milano, Via Celoria n10, 20133 Milano, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Musella</LastName><ForeName>Vincenzo</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Department of Health Science, University "Magna Græcia" of Catanzaro, Viale Europa, 88100 Catanzaro, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Britti</LastName><ForeName>Domenico</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Health Science, University "Magna Græcia" of Catanzaro, Viale Europa, 88100 Catanzaro, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sanguinetti</LastName><ForeName>Maurizio</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Basic Biotechnological Sciences, Intensivological and Perioperative Clinics, Università Cattolica del Sacro Cuore, Largo S. Vito n1, 00168 Rome, Italy; Dipartimento Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario Gemelli IRCCS, Largo S. Vito n8, 00168 Rome, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Urbani</LastName><ForeName>Andrea</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Basic Biotechnological Sciences, Intensivological and Perioperative Clinics, Università Cattolica del Sacro Cuore, Largo S. Vito n1, 00168 Rome, Italy; Dipartimento Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario Gemelli IRCCS, Largo S. Vito n8, 00168 Rome, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Roncada</LastName><ForeName>Paola</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Health Science, University "Magna Græcia" of Catanzaro, Viale Europa, 88100 Catanzaro, Italy. Electronic address: roncada@unicz.it.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>03</Month><Day>17</Day></ArticleDate></Article><MedlineJournalInfo><Country>France</Country><MedlineTA>Microbes Infect</MedlineTA><NlmUniqueID>100883508</NlmUniqueID><ISSNLinking>1286-4579</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">COVID-19</Keyword><Keyword MajorTopicYN="N">Canine respiratory coronavirus</Keyword><Keyword MajorTopicYN="N">Coronavirus</Keyword><Keyword MajorTopicYN="N">Immunization</Keyword><Keyword MajorTopicYN="N">One health</Keyword><Keyword MajorTopicYN="N">SARS-CoV-2</Keyword></KeywordList><CoiStatement>Declaration of Competing Interest The authors declare no conflict of interest.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>03</Month><Day>02</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>03</Month><Day>11</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>3</Month><Day>21</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>3</Month><Day>21</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>3</Month><Day>21</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32194253</ArticleId><ArticleId IdType="pii">S1286-4579(20)30048-4</ArticleId><ArticleId IdType="doi">10.1016/j.micinf.2020.03.002</ArticleId><ArticleId IdType="pmc">PMC7102648</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Int J Hyg 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