Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19).
Identifieur interne : 000495 ( PubMed/Curation ); précédent : 000494; suivant : 000496Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19).
Auteurs : Riccardo M. Inciardi [Italie] ; Laura Lupi [Italie] ; Gregorio Zaccone [Italie] ; Leonardo Italia [Italie] ; Michela Raffo [Italie] ; Daniela Tomasoni [Italie] ; Dario S. Cani [Italie] ; Manuel Cerini [Italie] ; Davide Farina [Italie] ; Emanuele Gavazzi [Italie] ; Roberto Maroldi [Italie] ; Marianna Adamo [Italie] ; Enrico Ammirati [Italie] ; Gianfranco Sinagra [Italie] ; Carlo M. Lombardi [Italie] ; Marco Metra [Italie]Source :
- JAMA cardiology [ 2380-6591 ] ; 2020.
Abstract
Virus infection has been widely described as one of the most common causes of myocarditis. However, less is known about the cardiac involvement as a complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
DOI: 10.1001/jamacardio.2020.1096
PubMed: 32219357
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Inciardi</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Lupi, Laura" sort="Lupi, Laura" uniqKey="Lupi L" first="Laura" last="Lupi">Laura Lupi</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Zaccone, Gregorio" sort="Zaccone, Gregorio" uniqKey="Zaccone G" first="Gregorio" last="Zaccone">Gregorio Zaccone</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Italia, Leonardo" sort="Italia, Leonardo" uniqKey="Italia L" first="Leonardo" last="Italia">Leonardo Italia</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Raffo, Michela" sort="Raffo, Michela" uniqKey="Raffo M" first="Michela" last="Raffo">Michela Raffo</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Tomasoni, Daniela" sort="Tomasoni, Daniela" uniqKey="Tomasoni D" first="Daniela" last="Tomasoni">Daniela Tomasoni</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Cani, Dario S" sort="Cani, Dario S" uniqKey="Cani D" first="Dario S" last="Cani">Dario S. Cani</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Cerini, Manuel" sort="Cerini, Manuel" uniqKey="Cerini M" first="Manuel" last="Cerini">Manuel Cerini</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Farina, Davide" sort="Farina, Davide" uniqKey="Farina D" first="Davide" last="Farina">Davide Farina</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Radiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Radiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Gavazzi, Emanuele" sort="Gavazzi, Emanuele" uniqKey="Gavazzi E" first="Emanuele" last="Gavazzi">Emanuele Gavazzi</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Radiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Radiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Maroldi, Roberto" sort="Maroldi, Roberto" uniqKey="Maroldi R" first="Roberto" last="Maroldi">Roberto Maroldi</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Radiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Radiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Adamo, Marianna" sort="Adamo, Marianna" uniqKey="Adamo M" first="Marianna" last="Adamo">Marianna Adamo</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Ammirati, Enrico" sort="Ammirati, Enrico" uniqKey="Ammirati E" first="Enrico" last="Ammirati">Enrico Ammirati</name><affiliation wicri:level="1"><nlm:affiliation>"De Gasperis" Cardio Center and Transplant Center, Niguarda Hospital, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>"De Gasperis" Cardio Center and Transplant Center, Niguarda Hospital, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Sinagra, Gianfranco" sort="Sinagra, Gianfranco" uniqKey="Sinagra G" first="Gianfranco" last="Sinagra">Gianfranco Sinagra</name><affiliation wicri:level="1"><nlm:affiliation>Cardiovascular Department, "Ospedali Riuniti" and University of Trieste, Trieste, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Cardiovascular Department, "Ospedali Riuniti" and University of Trieste, Trieste</wicri:regionArea></affiliation></author><author><name sortKey="Lombardi, Carlo M" sort="Lombardi, Carlo M" uniqKey="Lombardi C" first="Carlo M" last="Lombardi">Carlo M. Lombardi</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Metra, Marco" sort="Metra, Marco" uniqKey="Metra M" first="Marco" last="Metra">Marco Metra</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32219357</idno><idno type="pmid">32219357</idno><idno type="doi">10.1001/jamacardio.2020.1096</idno><idno type="wicri:Area/PubMed/Corpus">000495</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000495</idno><idno type="wicri:Area/PubMed/Curation">000495</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000495</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19).</title><author><name sortKey="Inciardi, Riccardo M" sort="Inciardi, Riccardo M" uniqKey="Inciardi R" first="Riccardo M" last="Inciardi">Riccardo M. Inciardi</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Lupi, Laura" sort="Lupi, Laura" uniqKey="Lupi L" first="Laura" last="Lupi">Laura Lupi</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Zaccone, Gregorio" sort="Zaccone, Gregorio" uniqKey="Zaccone G" first="Gregorio" last="Zaccone">Gregorio Zaccone</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Italia, Leonardo" sort="Italia, Leonardo" uniqKey="Italia L" first="Leonardo" last="Italia">Leonardo Italia</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Raffo, Michela" sort="Raffo, Michela" uniqKey="Raffo M" first="Michela" last="Raffo">Michela Raffo</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Tomasoni, Daniela" sort="Tomasoni, Daniela" uniqKey="Tomasoni D" first="Daniela" last="Tomasoni">Daniela Tomasoni</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Cani, Dario S" sort="Cani, Dario S" uniqKey="Cani D" first="Dario S" last="Cani">Dario S. Cani</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Cerini, Manuel" sort="Cerini, Manuel" uniqKey="Cerini M" first="Manuel" last="Cerini">Manuel Cerini</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Farina, Davide" sort="Farina, Davide" uniqKey="Farina D" first="Davide" last="Farina">Davide Farina</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Radiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Radiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Gavazzi, Emanuele" sort="Gavazzi, Emanuele" uniqKey="Gavazzi E" first="Emanuele" last="Gavazzi">Emanuele Gavazzi</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Radiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Radiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Maroldi, Roberto" sort="Maroldi, Roberto" uniqKey="Maroldi R" first="Roberto" last="Maroldi">Roberto Maroldi</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Radiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Radiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Adamo, Marianna" sort="Adamo, Marianna" uniqKey="Adamo M" first="Marianna" last="Adamo">Marianna Adamo</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Ammirati, Enrico" sort="Ammirati, Enrico" uniqKey="Ammirati E" first="Enrico" last="Ammirati">Enrico Ammirati</name><affiliation wicri:level="1"><nlm:affiliation>"De Gasperis" Cardio Center and Transplant Center, Niguarda Hospital, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>"De Gasperis" Cardio Center and Transplant Center, Niguarda Hospital, Milan</wicri:regionArea></affiliation></author><author><name sortKey="Sinagra, Gianfranco" sort="Sinagra, Gianfranco" uniqKey="Sinagra G" first="Gianfranco" last="Sinagra">Gianfranco Sinagra</name><affiliation wicri:level="1"><nlm:affiliation>Cardiovascular Department, "Ospedali Riuniti" and University of Trieste, Trieste, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Cardiovascular Department, "Ospedali Riuniti" and University of Trieste, Trieste</wicri:regionArea></affiliation></author><author><name sortKey="Lombardi, Carlo M" sort="Lombardi, Carlo M" uniqKey="Lombardi C" first="Carlo M" last="Lombardi">Carlo M. Lombardi</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author><author><name sortKey="Metra, Marco" sort="Metra, Marco" uniqKey="Metra M" first="Marco" last="Metra">Marco Metra</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia</wicri:regionArea></affiliation></author></analytic><series><title level="j">JAMA cardiology</title><idno type="eISSN">2380-6591</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Virus infection has been widely described as one of the most common causes of myocarditis. However, less is known about the cardiac involvement as a complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32219357</PMID><DateRevised><Year>2020</Year><Month>03</Month><Day>28</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">2380-6591</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2020</Year><Month>Mar</Month><Day>27</Day></PubDate></JournalIssue><Title>JAMA cardiology</Title><ISOAbbreviation>JAMA Cardiol</ISOAbbreviation></Journal><ArticleTitle>Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19).</ArticleTitle><ELocationID EIdType="doi" ValidYN="Y">10.1001/jamacardio.2020.1096</ELocationID><Abstract><AbstractText Label="Importance" NlmCategory="UNASSIGNED">Virus infection has been widely described as one of the most common causes of myocarditis. However, less is known about the cardiac involvement as a complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.</AbstractText><AbstractText Label="Objective" NlmCategory="UNASSIGNED">To describe the presentation of acute myocardial inflammation in a patient with coronavirus disease 2019 (COVID-19) who recovered from the influenzalike syndrome and developed fatigue and signs and symptoms of heart failure a week after upper respiratory tract symptoms.</AbstractText><AbstractText Label="Design, Setting, and Participant" NlmCategory="UNASSIGNED">This case report describes an otherwise healthy 53-year-old woman who tested positive for COVID-19 and was admitted to the cardiac care unit in March 2020 for acute myopericarditis with systolic dysfunction, confirmed on cardiac magnetic resonance imaging, the week after onset of fever and dry cough due to COVID-19. The patient did not show any respiratory involvement during the clinical course.</AbstractText><AbstractText Label="Exposure" NlmCategory="UNASSIGNED">Cardiac involvement with COVID-19.</AbstractText><AbstractText Label="Main Outcomes and Measures" NlmCategory="UNASSIGNED">Detection of cardiac involvement with an increase in levels of N-terminal pro-brain natriuretic peptide (NT-proBNP) and high-sensitivity troponin T, echocardiography changes, and diffuse biventricular myocardial edema and late gadolinium enhancement on cardiac magnetic resonance imaging.</AbstractText><AbstractText Label="Results" NlmCategory="UNASSIGNED">An otherwise healthy 53-year-old white woman presented to the emergency department with severe fatigue. She described fever and dry cough the week before. She was afebrile but hypotensive; electrocardiography showed diffuse ST elevation, and elevated high-sensitivity troponin T and NT-proBNP levels were detected. Findings on chest radiography were normal. There was no evidence of obstructive coronary disease on coronary angiography. Based on the COVID-19 outbreak, a nasopharyngeal swab was performed, with a positive result for SARS-CoV-2 on real-time reverse transcriptase-polymerase chain reaction assay. Cardiac magnetic resonance imaging showed increased wall thickness with diffuse biventricular hypokinesis, especially in the apical segments, and severe left ventricular dysfunction (left ventricular ejection fraction of 35%). Short tau inversion recovery and T2-mapping sequences showed marked biventricular myocardial interstitial edema, and there was also diffuse late gadolinium enhancement involving the entire biventricular wall. There was a circumferential pericardial effusion that was most notable around the right cardiac chambers. These findings were all consistent with acute myopericarditis. She was treated with dobutamine, antiviral drugs (lopinavir/ritonavir), steroids, chloroquine, and medical treatment for heart failure, with progressive clinical and instrumental stabilization.</AbstractText><AbstractText Label="Conclusions and Relevance" NlmCategory="UNASSIGNED">This case highlights cardiac involvement as a complication associated with COVID-19, even without symptoms and signs of interstitial pneumonia.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Inciardi</LastName><ForeName>Riccardo M</ForeName><Initials>RM</Initials><AffiliationInfo><Affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lupi</LastName><ForeName>Laura</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zaccone</LastName><ForeName>Gregorio</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Italia</LastName><ForeName>Leonardo</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Raffo</LastName><ForeName>Michela</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tomasoni</LastName><ForeName>Daniela</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cani</LastName><ForeName>Dario S</ForeName><Initials>DS</Initials><AffiliationInfo><Affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cerini</LastName><ForeName>Manuel</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Farina</LastName><ForeName>Davide</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Institute of Radiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gavazzi</LastName><ForeName>Emanuele</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Institute of Radiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Maroldi</LastName><ForeName>Roberto</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Institute of Radiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Adamo</LastName><ForeName>Marianna</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ammirati</LastName><ForeName>Enrico</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>"De Gasperis" Cardio Center and Transplant Center, Niguarda Hospital, Milan, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sinagra</LastName><ForeName>Gianfranco</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Cardiovascular Department, "Ospedali Riuniti" and University of Trieste, Trieste, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lombardi</LastName><ForeName>Carlo M</ForeName><Initials>CM</Initials><AffiliationInfo><Affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Metra</LastName><ForeName>Marco</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Institute of Cardiology, Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, Brescia, Italy.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>03</Month><Day>27</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>JAMA Cardiol</MedlineTA><NlmUniqueID>101676033</NlmUniqueID></MedlineJournalInfo><CitationSubset>IM</CitationSubset></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>3</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>3</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>3</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32219357</ArticleId><ArticleId IdType="pii">2763843</ArticleId><ArticleId IdType="doi">10.1001/jamacardio.2020.1096</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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