Serological Assays for SARS-CoV-2 Infectious Disease: Benefits, Limitations and Perspectives.
Identifieur interne : 000175 ( PubMed/Curation ); précédent : 000174; suivant : 000176Serological Assays for SARS-CoV-2 Infectious Disease: Benefits, Limitations and Perspectives.
Auteurs : Maria Infantino [Italie] ; Arianna Damiani [Italie] ; Francesca Li Gobbi [Italie] ; Valentina Grossi [Italie] ; Barbara Lari [Italie] ; Donatella Macchia [Italie] ; Patrizia Casprini [Italie] ; Francesca Veneziani [Italie] ; Danilo Villalta [Italie] ; Nicola Bizzaro [Italie] ; Piero Cappelletti [Italie] ; Martina Fabris [Italie] ; Luca Quartuccio [Italie] ; Maurizio Benucci [Italie] ; Mariangela Manfredi [Italie]Source :
- The Israel Medical Association journal : IMAJ [ 1565-1088 ] ; 2020.
Descripteurs français
- KwdFr :
- ARN viral (sang), Anticorps antiviraux (sang), Coronavirus (génétique), Coronavirus (immunologie), Coronavirus (isolement et purification), Humains, Immunoglobuline G (immunologie), Immunoglobuline G (sang), Immunoglobuline M (immunologie), Immunoglobuline M (sang), Infections à coronavirus (diagnostic), Infections à coronavirus (sang), Infections à coronavirus (épidémiologie), Lymphocytes T CD4+ (immunologie), Lymphocytes T CD8+ (immunologie), Pandémies, Pneumopathie virale (diagnostic), Pneumopathie virale (sang), Pneumopathie virale (épidémiologie), RT-PCR, Syndrome respiratoire aigu sévère (immunologie), Techniques de laboratoire clinique, Test ELISA, Tests sérologiques ().
- MESH :
- diagnostic : Infections à coronavirus, Pneumopathie virale.
- génétique : Coronavirus.
- immunologie : Coronavirus, Immunoglobuline G, Immunoglobuline M, Lymphocytes T CD4+, Lymphocytes T CD8+, Syndrome respiratoire aigu sévère.
- isolement et purification : Coronavirus.
- sang : ARN viral, Anticorps antiviraux, Immunoglobuline G, Immunoglobuline M, Infections à coronavirus, Pneumopathie virale.
- épidémiologie : Infections à coronavirus, Pneumopathie virale.
- Humains, Pandémies, RT-PCR, Techniques de laboratoire clinique, Test ELISA, Tests sérologiques.
English descriptors
- KwdEn :
- Antibodies, Viral (blood), Betacoronavirus, CD4-Positive T-Lymphocytes (immunology), CD8-Positive T-Lymphocytes (immunology), Clinical Laboratory Techniques, Coronavirus (genetics), Coronavirus (immunology), Coronavirus (isolation & purification), Coronavirus Infections (blood), Coronavirus Infections (diagnosis), Coronavirus Infections (epidemiology), Enzyme-Linked Immunosorbent Assay, Humans, Immunoglobulin G (blood), Immunoglobulin G (immunology), Immunoglobulin M (blood), Immunoglobulin M (immunology), Pandemics, Pneumonia, Viral (blood), Pneumonia, Viral (diagnosis), Pneumonia, Viral (epidemiology), RNA, Viral (blood), Reverse Transcriptase Polymerase Chain Reaction, Serologic Tests (methods), Severe Acute Respiratory Syndrome (immunology).
- MESH :
- chemical , blood : Antibodies, Viral, Immunoglobulin G, Immunoglobulin M, RNA, Viral.
- blood : Coronavirus Infections, Pneumonia, Viral.
- diagnosis : Coronavirus Infections, Pneumonia, Viral.
- epidemiology : Coronavirus Infections, Pneumonia, Viral.
- genetics : Coronavirus.
- immunology : CD4-Positive T-Lymphocytes, CD8-Positive T-Lymphocytes, Coronavirus, Immunoglobulin G, Immunoglobulin M, Severe Acute Respiratory Syndrome.
- isolation & purification : Coronavirus.
- methods : Serologic Tests.
- Betacoronavirus, Clinical Laboratory Techniques, Enzyme-Linked Immunosorbent Assay, Humans, Pandemics, Reverse Transcriptase Polymerase Chain Reaction.
PubMed: 32286019
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Giovanni di Dio Hospital, Florence, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Reumatology Unit, S. Giovanni di Dio Hospital, Florence</wicri:regionArea></affiliation></author><author><name sortKey="Grossi, Valentina" sort="Grossi, Valentina" uniqKey="Grossi V" first="Valentina" last="Grossi">Valentina Grossi</name><affiliation wicri:level="1"><nlm:affiliation>Immunology and Allergy Laboratory Unit, San Giovanni di Dio Hospital, Florence, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Immunology and Allergy Laboratory Unit, San Giovanni di Dio Hospital, Florence</wicri:regionArea></affiliation></author><author><name sortKey="Lari, Barbara" sort="Lari, Barbara" uniqKey="Lari B" first="Barbara" last="Lari">Barbara Lari</name><affiliation wicri:level="1"><nlm:affiliation>Immunology and Allergy Laboratory Unit, San Giovanni di Dio Hospital, Florence, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Immunology and Allergy Laboratory Unit, San Giovanni di Dio Hospital, Florence</wicri:regionArea></affiliation></author><author><name sortKey="Macchia, Donatella" sort="Macchia, Donatella" uniqKey="Macchia D" first="Donatella" last="Macchia">Donatella Macchia</name><affiliation wicri:level="1"><nlm:affiliation>Allergy and Clinical Immunology, San Giovanni di Dio Hospital, Florence, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Allergy and Clinical Immunology, San Giovanni di Dio Hospital, Florence</wicri:regionArea></affiliation></author><author><name sortKey="Casprini, Patrizia" sort="Casprini, Patrizia" uniqKey="Casprini P" first="Patrizia" last="Casprini">Patrizia Casprini</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Clinical Pathology and Immunoallergy, Florence-Prato, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Clinical Pathology and Immunoallergy, Florence-Prato</wicri:regionArea></affiliation></author><author><name sortKey="Veneziani, Francesca" sort="Veneziani, Francesca" uniqKey="Veneziani F" first="Francesca" last="Veneziani">Francesca Veneziani</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Clinical Pathology, San Giovanni di Dio Hospital, Florence, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Clinical Pathology, San Giovanni di Dio Hospital, Florence</wicri:regionArea></affiliation></author><author><name sortKey="Villalta, Danilo" sort="Villalta, Danilo" uniqKey="Villalta D" first="Danilo" last="Villalta">Danilo Villalta</name><affiliation wicri:level="1"><nlm:affiliation>Immunology and Allergy Unit, San Maria degli Angeli Hospital, Pordenone, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Immunology and Allergy Unit, San Maria degli Angeli Hospital, Pordenone</wicri:regionArea></affiliation></author><author><name sortKey="Bizzaro, Nicola" sort="Bizzaro, Nicola" uniqKey="Bizzaro N" first="Nicola" last="Bizzaro">Nicola Bizzaro</name><affiliation wicri:level="1"><nlm:affiliation>Laboratory of Clinical Pathology, San Antonio Hospital, Tolmezzo, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Laboratory of Clinical Pathology, San Antonio Hospital, Tolmezzo</wicri:regionArea></affiliation></author><author><name sortKey="Cappelletti, Piero" sort="Cappelletti, Piero" uniqKey="Cappelletti P" first="Piero" last="Cappelletti">Piero Cappelletti</name><affiliation wicri:level="1"><nlm:affiliation>SIPMeL, Castelfranco Veneto, Veneto, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>SIPMeL, Castelfranco Veneto, Veneto</wicri:regionArea></affiliation></author><author><name sortKey="Fabris, Martina" sort="Fabris, Martina" uniqKey="Fabris M" first="Martina" last="Fabris">Martina Fabris</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Clinical Pathology, University of Udine, Udine, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Institute of Clinical Pathology, University of Udine, Udine</wicri:regionArea></affiliation></author><author><name sortKey="Quartuccio, Luca" sort="Quartuccio, Luca" uniqKey="Quartuccio L" first="Luca" last="Quartuccio">Luca Quartuccio</name><affiliation wicri:level="1"><nlm:affiliation>Clinic of Rheumatology, ASUFC, Department of Medicine (DAME), University of Udine, Udine, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Clinic of Rheumatology, ASUFC, Department of Medicine (DAME), University of Udine, Udine</wicri:regionArea></affiliation></author><author><name sortKey="Benucci, Maurizio" sort="Benucci, Maurizio" uniqKey="Benucci M" first="Maurizio" last="Benucci">Maurizio Benucci</name><affiliation wicri:level="1"><nlm:affiliation>Reumatology Unit, S. Giovanni di Dio Hospital, Florence, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Reumatology Unit, S. Giovanni di Dio Hospital, Florence</wicri:regionArea></affiliation></author><author><name sortKey="Manfredi, Mariangela" sort="Manfredi, Mariangela" uniqKey="Manfredi M" first="Mariangela" last="Manfredi">Mariangela Manfredi</name><affiliation wicri:level="1"><nlm:affiliation>Immunology and Allergy Laboratory Unit, San Giovanni di Dio Hospital, Florence, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Immunology and Allergy Laboratory Unit, San Giovanni di Dio Hospital, Florence</wicri:regionArea></affiliation></author></analytic><series><title level="j">The Israel Medical Association journal : IMAJ</title><idno type="ISSN">1565-1088</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antibodies, Viral (blood)</term><term>Betacoronavirus</term><term>CD4-Positive T-Lymphocytes (immunology)</term><term>CD8-Positive T-Lymphocytes (immunology)</term><term>Clinical Laboratory Techniques</term><term>Coronavirus (genetics)</term><term>Coronavirus (immunology)</term><term>Coronavirus (isolation & purification)</term><term>Coronavirus Infections (blood)</term><term>Coronavirus Infections (diagnosis)</term><term>Coronavirus Infections (epidemiology)</term><term>Enzyme-Linked Immunosorbent Assay</term><term>Humans</term><term>Immunoglobulin G (blood)</term><term>Immunoglobulin G (immunology)</term><term>Immunoglobulin M (blood)</term><term>Immunoglobulin M (immunology)</term><term>Pandemics</term><term>Pneumonia, Viral (blood)</term><term>Pneumonia, Viral (diagnosis)</term><term>Pneumonia, Viral (epidemiology)</term><term>RNA, Viral (blood)</term><term>Reverse Transcriptase Polymerase Chain Reaction</term><term>Serologic Tests (methods)</term><term>Severe Acute Respiratory Syndrome (immunology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ARN viral (sang)</term><term>Anticorps antiviraux (sang)</term><term>Coronavirus (génétique)</term><term>Coronavirus (immunologie)</term><term>Coronavirus (isolement et purification)</term><term>Humains</term><term>Immunoglobuline G (immunologie)</term><term>Immunoglobuline G (sang)</term><term>Immunoglobuline M (immunologie)</term><term>Immunoglobuline M (sang)</term><term>Infections à coronavirus (diagnostic)</term><term>Infections à coronavirus (sang)</term><term>Infections à coronavirus (épidémiologie)</term><term>Lymphocytes T CD4+ (immunologie)</term><term>Lymphocytes T CD8+ (immunologie)</term><term>Pandémies</term><term>Pneumopathie virale (diagnostic)</term><term>Pneumopathie virale (sang)</term><term>Pneumopathie virale (épidémiologie)</term><term>RT-PCR</term><term>Syndrome respiratoire aigu sévère (immunologie)</term><term>Techniques de laboratoire clinique</term><term>Test ELISA</term><term>Tests sérologiques ()</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Viral</term><term>Immunoglobulin G</term><term>Immunoglobulin M</term><term>RNA, Viral</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Coronavirus</term><term>Immunoglobuline G</term><term>Immunoglobuline M</term><term>Lymphocytes T CD4+</term><term>Lymphocytes T CD8+</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>CD4-Positive T-Lymphocytes</term><term>CD8-Positive T-Lymphocytes</term><term>Coronavirus</term><term>Immunoglobulin G</term><term>Immunoglobulin M</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Serologic Tests</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>ARN viral</term><term>Anticorps antiviraux</term><term>Immunoglobuline G</term><term>Immunoglobuline M</term><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Betacoronavirus</term><term>Clinical Laboratory Techniques</term><term>Enzyme-Linked Immunosorbent Assay</term><term>Humans</term><term>Pandemics</term><term>Reverse Transcriptase Polymerase Chain Reaction</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Humains</term><term>Pandémies</term><term>RT-PCR</term><term>Techniques de laboratoire clinique</term><term>Test ELISA</term><term>Tests sérologiques</term></keywords></textClass></profileDesc></teiHeader></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32286019</PMID><DateCompleted><Year>2020</Year><Month>04</Month><Day>17</Day></DateCompleted><DateRevised><Year>2020</Year><Month>04</Month><Day>17</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">1565-1088</ISSN><JournalIssue CitedMedium="Internet"><Volume>22</Volume><Issue>4</Issue><PubDate><Year>2020</Year><Month>04</Month></PubDate></JournalIssue><Title>The Israel Medical Association journal : IMAJ</Title><ISOAbbreviation>Isr. Med. Assoc. J.</ISOAbbreviation></Journal><ArticleTitle>Serological Assays for SARS-CoV-2 Infectious Disease: Benefits, Limitations and Perspectives.</ArticleTitle><Pagination><MedlinePgn>203-210</MedlinePgn></Pagination><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Infantino</LastName><ForeName>Maria</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Immunology and Allergy Laboratory Unit, San Giovanni di Dio Hospital, Florence, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Damiani</LastName><ForeName>Arianna</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Florence, Florence, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gobbi</LastName><ForeName>Francesca Li</ForeName><Initials>FL</Initials><AffiliationInfo><Affiliation>Reumatology Unit, S. Giovanni di Dio Hospital, Florence, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Grossi</LastName><ForeName>Valentina</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Immunology and Allergy Laboratory Unit, San Giovanni di Dio Hospital, Florence, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lari</LastName><ForeName>Barbara</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Immunology and Allergy Laboratory Unit, San Giovanni di Dio Hospital, Florence, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Macchia</LastName><ForeName>Donatella</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Allergy and Clinical Immunology, San Giovanni di Dio Hospital, Florence, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Casprini</LastName><ForeName>Patrizia</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Laboratory of Clinical Pathology and Immunoallergy, Florence-Prato, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Veneziani</LastName><ForeName>Francesca</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Laboratory of Clinical Pathology, San Giovanni di Dio Hospital, Florence, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Villalta</LastName><ForeName>Danilo</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Immunology and Allergy Unit, San Maria degli Angeli Hospital, Pordenone, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bizzaro</LastName><ForeName>Nicola</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Laboratory of Clinical Pathology, San Antonio Hospital, Tolmezzo, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cappelletti</LastName><ForeName>Piero</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>SIPMeL, Castelfranco Veneto, Veneto, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fabris</LastName><ForeName>Martina</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Institute of Clinical Pathology, University of Udine, Udine, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Quartuccio</LastName><ForeName>Luca</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Clinic of Rheumatology, ASUFC, Department of Medicine (DAME), University of Udine, Udine, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Benucci</LastName><ForeName>Maurizio</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Reumatology Unit, S. Giovanni di Dio Hospital, Florence, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Manfredi</LastName><ForeName>Mariangela</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Immunology and Allergy Laboratory Unit, San Giovanni di Dio Hospital, Florence, Italy.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Israel</Country><MedlineTA>Isr Med Assoc J</MedlineTA><NlmUniqueID>100930740</NlmUniqueID></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000914">Antibodies, Viral</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007074">Immunoglobulin G</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007075">Immunoglobulin M</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D012367">RNA, Viral</NameOfSubstance></Chemical></ChemicalList><SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName><SupplMeshName Type="Protocol" UI="C000657964">COVID-19 diagnostic testing</SupplMeshName><SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName></SupplMeshList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000914" MajorTopicYN="N">Antibodies, Viral</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="N">Betacoronavirus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015496" MajorTopicYN="N">CD4-Positive T-Lymphocytes</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018414" MajorTopicYN="N">CD8-Positive T-Lymphocytes</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D019411" MajorTopicYN="N">Clinical Laboratory Techniques</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017934" MajorTopicYN="N">Coronavirus</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004797" MajorTopicYN="N">Enzyme-Linked Immunosorbent Assay</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007074" MajorTopicYN="N">Immunoglobulin G</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007075" MajorTopicYN="N">Immunoglobulin M</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012367" MajorTopicYN="N">RNA, Viral</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020133" MajorTopicYN="N">Reverse Transcriptase Polymerase Chain Reaction</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012698" MajorTopicYN="N">Serologic Tests</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D045169" MajorTopicYN="N">Severe Acute Respiratory Syndrome</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate 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