| Ident. | Authors (with country if any) | Title |
|---|
| 001C10 (2008) |
Tao Ma ; Li Liu ; Hai Xue ; Li Li ; Chunyan Han ; Lin Wang ; Zhiwei Chen ; Gang Liu | Chemical library and structure-activity relationships of 11-demethyl-12-oxo calanolide A analogues as anti-HIV-1 agents. |
| 001D57 (2007) |
Chih-Chun Wen ; Yueh-Hsiung Kuo ; Jia-Tsrong Jan ; Po-Huang Liang ; Sheng-Yang Wang ; Hong-Gi Liu ; Ching-Kuo Lee ; Shang-Tzen Chang ; Chih-Jung Kuo ; Shoei-Sheng Lee ; Chia-Chung Hou ; Pei-Wen Hsiao ; Shih-Chang Chien ; Lie-Fen Shyur ; Ning-Sun Yang | Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus. |
| 001F80 (2006) |
Christopher Mcguigan ; Alshaimaa Hassan-Abdallah ; Sheila Srinivasan ; Yikang Wang ; Adam Siddiqui ; Susan M. Daluge ; Kristjan S. Gudmundsson ; Huiqiang Zhou ; Ed W. Mclean ; Jennifer P. Peckham ; Thimysta C. Burnette ; Harry Marr ; Richard Hazen ; Lynn D. Condreay ; Lance Johnson ; Jan Balzarini | Application of phosphoramidate ProTide technology significantly improves antiviral potency of carbocyclic adenosine derivatives. |
| 002123 (2006) |
I-Lin Lu ; Neeraj Mahindroo ; Po-Huang Liang ; Yi-Hui Peng ; Chih-Jung Kuo ; Keng-Chang Tsai ; Hsing-Pang Hsieh ; Yu-Sheng Chao ; Su-Ying Wu | Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease. |
| 002145 (2006) |
Syaulan Yang ; Shu-Jen Chen ; Min-Feng Hsu ; Jen-Dar Wu ; Chien-Te K. Tseng ; Yu-Fan Liu ; Hua-Chien Chen ; Chun-Wei Kuo ; Chi-Shen Wu ; Li-Wen Chang ; Wen-Chang Chen ; Shao-Ying Liao ; Teng-Yuan Chang ; Hsin-Hui Hung ; Hui-Lin Shr ; Cheng-Yuan Liu ; Yu-An Huang ; Ling-Yin Chang ; Jen-Chi Hsu ; Clarence J. Peters ; Andrew H-J Wang ; Ming-Chu Hsu | Synthesis, crystal structure, structure-activity relationships, and antiviral activity of a potent SARS coronavirus 3CL protease inhibitor. |
| 002212 (2006) |
Rakesh Kumar ; Wassila Semaine ; Monika Johar ; D Lorne J. Tyrrell ; Babita Agrawal | Effect of various pyrimidines possessing the 1-[(2-hydroxy-1-(hydroxymethyl)ethoxy)methyl] moiety, able to mimic natural 2'-deoxyribose, on wild-type and mutant hepatitis B virus replication. |
| 002213 (2006) |
Keng-Chang Tsai ; Shih-Yuan Chen ; Po-Huang Liang ; I-Lin Lu ; Neeraj Mahindroo ; Hsing-Pang Hsieh ; Yu-Sheng Chao ; Lincoln Liu ; Donald Liu ; Wei Lien ; Thy-Hou Lin ; Su-Ying Wu | Discovery of a novel family of SARS-CoV protease inhibitors by virtual screening and 3D-QSAR studies. |
| 002214 (2006) |
Lu Zhou ; Ying Liu ; Weilin Zhang ; Ping Wei ; Changkang Huang ; Jianfeng Pei ; Yaxia Yuan ; Luhua Lai | Isatin compounds as noncovalent SARS coronavirus 3C-like protease inhibitors. |
| 002260 (2006) |
Christophe Biot ; Wassim Daher ; Natascha Chavain ; Thierry Fandeur ; Jamal Khalife ; Daniel Dive ; Erik De Clercq | Design and synthesis of hydroxyferroquine derivatives with antimalarial and antiviral activities. |
| 002309 (2006) |
Roberto Di Santo ; Roberta Costi ; Alessandra Roux ; Marino Artico ; Antonio Lavecchia ; Luciana Marinelli ; Ettore Novellino ; Lucia Palmisano ; Mauro Andreotti ; Roberta Amici ; Clementina Maria Galluzzo ; Lucia Nencioni ; Anna Teresa Palamara ; Yves Pommier ; Christophe Marchand | Novel bifunctional quinolonyl diketo acid derivatives as HIV-1 integrase inhibitors: design, synthesis, biological activities, and mechanism of action. |
| 002358 (2006) |
Han-Zhong Zhang ; Hong Zhang ; William Kemnitzer ; Ben Tseng ; Jindrich Cinatl ; Martin Michaelis ; Hans Wilhelm Doerr ; Sui Xiong Cai | Design and synthesis of dipeptidyl glutaminyl fluoromethyl ketones as potent severe acute respiratory syndrome coronovirus (SARS-CoV) inhibitors. |
| 002359 (2006) |
Jong Hyun Cho ; Dale L. Bernard ; Robert W. Sidwell ; Earl R. Kern ; Chung K. Chu | Synthesis of cyclopentenyl carbocyclic nucleosides as potential antiviral agents against orthopoxviruses and SARS. |
| 002453 (2005) |
Caterina Fattorusso ; Sandra Gemma ; Stefania Butini ; Paul Huleatt ; Bruno Catalanotti ; Marco Persico ; Meri De Angelis ; Isabella Fiorini ; Vito Nacci ; Anna Ramunno ; Manuela Rodriquez ; Giovanni Greco ; Ettore Novellino ; Alberto Bergamini ; Stefano Marini ; Massimo Coletta ; Giovanni Maga ; Silvio Spadari ; Giuseppe Campiani | Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity. |
| 002477 (2005) |
Ulrich Kaeppler ; Nikolaus Stiefl ; Markus Schiller ; Radim Vicik ; Alexander Breuning ; Werner Schmitz ; Daniel Rupprecht ; Carsten Schmuck ; Knut Baumann ; John Ziebuhr ; Tanja Schirmeister | A new lead for nonpeptidic active-site-directed inhibitors of the severe acute respiratory syndrome coronavirus main protease discovered by a combination of screening and docking methods. |
| 002478 (2005) |
Arun K. Ghosh ; Kai Xi ; Kiira Ratia ; Bernard D. Santarsiero ; Wentao Fu ; Brian H. Harcourt ; Paul A. Rota ; Susan C. Baker ; Michael E. Johnson ; Andrew D. Mesecar | Design and synthesis of peptidomimetic severe acute respiratory syndrome chymotrypsin-like protease inhibitors. |
| 002675 (2005) |
Jiun-Jie Shie ; Jim-Min Fang ; Chih-Jung Kuo ; Tun-Hsun Kuo ; Po-Huang Liang ; Hung-Jyun Huang ; Wen-Bin Yang ; Chun-Hung Lin ; Jiun-Ling Chen ; Yin-Ta Wu ; Chi-Huey Wong | Discovery of potent anilide inhibitors against the severe acute respiratory syndrome 3CL protease. |
| 002881 (2005) |
Gerold Hoever ; Lidia Baltina ; Martin Michaelis ; Rimma Kondratenko ; Lia Baltina ; Genrich A. Tolstikov ; Hans W. Doerr ; Jindrich Cinatl | Antiviral activity of glycyrrhizic acid derivatives against SARS-coronavirus. |
| 002F47 (2004) |
Jeffrey H. Toney ; Sonia Navas-Martín ; Susan R. Weiss ; Andreas Koeller | Sabadinine: a potential non-peptide anti-severe acute-respiratory-syndrome agent identified using structure-aided design. |
| 003449 (2003) |
Angelo Ranise ; Andrea Spallarossa ; Silvia Schenone ; Olga Bruno ; Francesco Bondavalli ; Laura Vargiu ; Tiziana Marceddu ; Massimo Mura ; Paolo La Colla ; Alessandra Pani | Design, synthesis, SAR, and molecular modeling studies of acylthiocarbamates: a novel series of potent non-nucleoside HIV-1 reverse transcriptase inhibitors structurally related to phenethylthiazolylthiourea derivatives. |
| 003476 (2000) |
F. Zouhiri ; J F Mouscadet ; K. Mekouar ; D. Desmaële ; D. Savouré ; H. Leh ; F. Subra ; M. Le Bret ; C. Auclair ; J. D'Angelo | Structure-activity relationships and binding mode of styrylquinolines as potent inhibitors of HIV-1 integrase and replication of HIV-1 in cell culture. |
| 003490 (1998) |
M. Artico ; R. Di Santo ; R. Costi ; E. Novellino ; G. Greco ; S. Massa ; E. Tramontano ; M E Marongiu ; A. De Montis ; P. La Colla | Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: synthesis, biological evaluation, and molecular modeling. |
