| Ident. | Authors (with country if any) | Title |
|---|
| 000702 (2020) |
Guangdi Li ; Erik De Clercq | Therapeutic options for the 2019 novel coronavirus (2019-nCoV). |
| 000882 (2019) |
Tong Zhao ; Qing Meng ; Dongwei Kang ; Jianbo Ji ; Erik De Clercq ; Christophe Pannecouque ; Xinyong Liu ; Peng Zhan | Discovery of novel indolylarylsulfones as potent HIV-1 NNRTIs via structure-guided scaffold morphing. |
| 000905 (2019) |
Kaijun Jin ; Yali Sang ; Sheng Han ; Erik De Clercq ; Christophe Pannecouque ; Ge Meng ; Fener Chen | Synthesis and biological evaluation of dihydroquinazoline-2-amines as potent non-nucleoside reverse transcriptase inhibitors of wild-type and mutant HIV-1 strains. |
| 000942 (2019) |
Zhao Wang ; Zhao Yu ; Dongwei Kang ; Jian Zhang ; Ye Tian ; Dirk Daelemans ; Erik De Clercq ; Christophe Pannecouque ; Peng Zhan ; Xinyong Liu | Design, synthesis and biological evaluation of novel acetamide-substituted doravirine and its prodrugs as potent HIV-1 NNRTIs. |
| 000A14 (2018) |
Xueyi Lu ; Jiapei Yang ; Dongwei Kang ; Ping Gao ; Dirk Daelemans ; Erik De Clercq ; Christophe Pannecouque ; Peng Zhan ; Xinyong Liu | The discovery of novel diarylpyri(mi)dine derivatives with high level activity against a wide variety of HIV-1 strains as well as against HIV-2. |
| 000A29 (2018) |
Zhongxia Zhou ; Tao Liu ; Dongwei Kang ; Zhipeng Huo ; Gaochan Wu ; Dirk Daelemans ; Erik De Clercq ; Christophe Pannecouque ; Peng Zhan ; Xinyong Liu | Discovery of novel diarylpyrimidines as potent HIV-1 NNRTIs by investigating the chemical space of a less explored "hydrophobic channel". |
| 000B05 (2017) |
Boshi Huang ; Xueshun Wang ; Xinhao Liu ; Zihui Chen ; Wanzhuo Li ; Songkai Sun ; Huiqing Liu ; Dirk Daelemans ; Erik De Clercq ; Christophe Pannecouque ; Peng Zhan ; Xinyong Liu | Discovery of novel DAPY-IAS hybrid derivatives as potential HIV-1 inhibitors using molecular hybridization based on crystallographic overlays. |
| 000C00 (2017) |
Xiao Li ; Ping Gao ; Boshi Huang ; Zhongxia Zhou ; Zhao Yu ; Zheng Yuan ; Huiqing Liu ; Christophe Pannecouque ; Dirk Daelemans ; Erik De Clercq ; Peng Zhan ; Xinyong Liu | Discovery of novel piperidine-substituted indolylarylsulfones as potent HIV NNRTIs via structure-guided scaffold morphing and fragment rearrangement. |
| 000C22 (2016) |
Xueyi Lu ; Xiao Li ; Jiapei Yang ; Boshi Huang ; Dongwei Kang ; Fabao Zhao ; Zhongxia Zhou ; Erik De Clercq ; Dirk Daelemans ; Christophe Pannecouque ; Peng Zhan ; Xinyong Liu | Arylazolyl(azinyl)thioacetanilides. Part 20: Discovery of novel purinylthioacetanilides derivatives as potent HIV-1 NNRTIs via a structure-based bioisosterism approach. |
| 000C80 (2016) |
Qing Meng ; Xuwang Chen ; Dongwei Kang ; Boshi Huang ; Wenxin Li ; Peng Zhan ; Dirk Daelemans ; Erik De Clercq ; Christophe Pannecouque ; Xinyong Liu | Design, synthesis and evaluation of novel HIV-1 NNRTIs with dual structural conformations targeting the entrance channel of the NNRTI binding pocket. |
| 000D14 (2016) |
Jiapei Yang ; Wenmin Chen ; Dongwei Kang ; Xueyi Lu ; Xiao Li ; Zhaoqiang Liu ; Boshi Huang ; Dirk Daelemans ; Christophe Pannecouque ; Erik De Clercq ; Peng Zhan ; Xinyong Liu | Design, synthesis and anti-HIV evaluation of novel diarylpyridine derivatives targeting the entrance channel of NNRTI binding pocket. |
| 000D84 (2015) |
Wenxin Li ; Xiao Li ; Erik De Clercq ; Peng Zhan ; Xinyong Liu | Discovery of potent HIV-1 non-nucleoside reverse transcriptase inhibitors from arylthioacetanilide structural motif. |
| 000E69 (2015) |
Boshi Huang ; Cuicui Li ; Wenmin Chen ; Tao Liu ; Mingyan Yu ; Lu Fu ; Yueyue Sun ; Huiqing Liu ; Erik De Clercq ; Christophe Pannecouque ; Jan Balzarini ; Peng Zhan ; Xinyong Liu | Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 3: optimization of [1,2,4]triazolo[1,5-a]pyrimidine core via structure-based and physicochemical property-driven approaches. |
| 000F10 (2015) |
Tao Liu ; Boshi Huang ; Ye Tian ; Xin Liang ; Hong Liu ; Huiqing Liu ; Peng Zhan ; Erik De Clercq ; Christophe Pannecouque ; Xinyong Liu | Design, Synthesis, and Biological Evaluation of Novel 4-Aminopiperidinyl-linked 3,5-Disubstituted-1,2,6-thiadiazine-1,1-dione Derivatives as HIV-1 NNRTIs. |
| 000F27 (2014) |
Zhaoqiang Liu ; Wenmin Chen ; Peng Zhan ; Erik De Clercq ; Christophe Pannecouque ; Xinyong Liu | Design, synthesis and anti-HIV evaluation of novel diarylnicotinamide derivatives (DANAs) targeting the entrance channel of the NNRTI binding pocket through structure-guided molecular hybridization. |
| 000F41 (2014) |
Xiao Li ; Xueyi Lu ; Wenmin Chen ; Huiqing Liu ; Peng Zhan ; Christophe Pannecouque ; Jan Balzarini ; Erik De Clercq ; Xinyong Liu | Arylazolyl(azinyl)thioacetanilides. Part 16: Structure-based bioisosterism design, synthesis and biological evaluation of novel pyrimidinylthioacetanilides as potent HIV-1 inhibitors. |
| 000F54 (2014) |
Liu Wang ; Ye Tian ; Wenmin Chen ; Hong Liu ; Peng Zhan ; Dongyue Li ; Huiqing Liu ; Erik De Clercq ; Christophe Pannecouque ; Xinyong Liu | Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 2: discovery of novel [1,2,4]Triazolo[1,5-a]pyrimidines using a structure-guided core-refining approach. |
| 001003 (2014) |
Xiao Li ; Wenmin Chen ; Ye Tian ; Huiqing Liu ; Peng Zhan ; Erik De Clercq ; Christophe Pannecouque ; Jan Balzarini ; Xinyong Liu | Discovery of novel diarylpyrimidines as potent HIV NNRTIs via a structure-guided core-refining approach. |
| 001019 (2014) |
Diwakar Rai ; Wenmin Chen ; Peng Zhan ; Hong Liu ; Ye Tian ; Xin Liang ; Erik De Clercq ; Christophe Pannecouque ; Jan Balzarini ; Xinyong Liu | Synthesis and anti-HIV activity of 4-(naphthalen-1-yl)-1,2,5-thiadiazol-3-hydroxyl derivatives. |
| 001033 (2014) |
Jun Wang ; Peng Zhan ; Zhenyu Li ; Huiqing Liu ; Erik De Clercq ; Christophe Pannecouque ; Xinyong Liu | Discovery of nitropyridine derivatives as potent HIV-1 non-nucleoside reverse transcriptase inhibitors via a structure-based core refining approach. |
| 001253 (2013) |
Dongyue Li ; Peng Zhan ; Huiqing Liu ; Christophe Pannecouque ; Jan Balzarini ; Erik De Clercq ; Xinyong Liu | Synthesis and biological evaluation of pyridazine derivatives as novel HIV-1 NNRTIs. |
