| Ident. | Authors (with country if any) | Title |
|---|
| 001043 (2014) |
Paul M. Scola ; Li-Qiang Sun ; Alan Xiangdong Wang ; Jie Chen ; Ny Sin ; Brian L. Venables ; Sing-Yuen Sit ; Yan Chen ; Anthony Cocuzza ; Donna M. Bilder ; Stanley V. D'Andrea ; Barbara Zheng ; Piyasena Hewawasam ; Yong Tu ; Jacques Friborg ; Paul Falk ; Dennis Hernandez ; Steven Levine ; Chaoqun Chen ; Fei Yu ; Amy K. Sheaffer ; Guangzhi Zhai ; Diana Barry ; Jay O. Knipe ; Yong-Hae Han ; Richard Schartman ; Maria Donoso ; Kathy Mosure ; Michael W. Sinz ; Tatyana Zvyaga ; Andrew C. Good ; Ramkumar Rajamani ; Kevin Kish ; Jeffrey Tredup ; Herbert E. Klei ; Qi Gao ; Luciano Mueller ; Richard J. Colonno ; Dennis M. Grasela ; Stephen P. Adams ; James Loy ; Paul C. Levesque ; Huabin Sun ; Hong Shi ; Lucy Sun ; William Warner ; Danshi Li ; Jialong Zhu ; Nicholas A. Meanwell ; Fiona Mcphee | The discovery of asunaprevir (BMS-650032), an orally efficacious NS3 protease inhibitor for the treatment of hepatitis C virus infection. |
| 001086 (2014) |
Wei Liu ; He-Min Zhu ; Guo-Jun Niu ; En-Zhi Shi ; Jie Chen ; Bo Sun ; Wei-Qiang Chen ; Hong-Gang Zhou ; Cheng Yang | Synthesis, modification and docking studies of 5-sulfonyl isatin derivatives as SARS-CoV 3C-like protease inhibitors. |
| 001134 (2013) |
Pillaiyar Thanigaimalai ; Sho Konno ; Takehito Yamamoto ; Yuji Koiwai ; Akihiro Taguchi ; Kentaro Takayama ; Fumika Yakushiji ; Kenichi Akaji ; Shen-En Chen ; Aurash Naser-Tavakolian ; Arne Schön ; Ernesto Freire ; Yoshio Hayashi | Development of potent dipeptide-type SARS-CoV 3CL protease inhibitors with novel P3 scaffolds: design, synthesis, biological evaluation, and docking studies. |
| 001138 (2013) |
Andy Kilianski ; Anna M. Mielech ; Xufang Deng ; Susan C. Baker | Assessing activity and inhibition of Middle East respiratory syndrome coronavirus papain-like and 3C-like proteases using luciferase-based biosensors. |
| 001157 (2013) |
Vathan Kumar ; Young-Sik Jung ; Po-Huang Liang | Anti-SARS coronavirus agents: a patent review (2008 - present). |
| 001165 (2013) |
Qi Zhao ; Erin Weber ; Haitao Yang | Recent developments on coronavirus main protease/3C like protease inhibitors. |
| 001179 (2013) |
Hyun Lee ; Shuyi Cao ; Kirk E. Hevener ; Lena Truong ; Joseph L. Gatuz ; Kavankumar Patel ; Arun K. Ghosh ; Michael E. Johnson | Synergistic inhibitor binding to the papain-like protease of human SARS coronavirus: mechanistic and inhibitor design implications. |
| 001189 (2013) |
Sivakoteswara Rao Mandadapu ; Pathum M. Weerawarna ; Allan M. Prior ; Roxanne Adeline Z. Uy ; Sridhar Aravapalli ; Kevin R. Alliston ; Gerald H. Lushington ; Yunjeong Kim ; Duy H. Hua ; Kyeong-Ok Chang ; William C. Groutas | Macrocyclic inhibitors of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus. |
| 001229 (2013) |
Zhilin Ren ; Liming Yan ; Ning Zhang ; Yu Guo ; Cheng Yang ; Zhiyong Lou ; Zihe Rao | The newly emerged SARS-like coronavirus HCoV-EMC also has an "Achilles' heel": current effective inhibitor targeting a 3C-like protease. |
| 001274 (2013) |
Sho Konno ; Pillaiyar Thanigaimalai ; Takehito Yamamoto ; Kiyohiko Nakada ; Rie Kakiuchi ; Kentaro Takayama ; Yuri Yamazaki ; Fumika Yakushiji ; Kenichi Akaji ; Yoshiaki Kiso ; Yuko Kawasaki ; Shen-En Chen ; Ernesto Freire ; Yoshio Hayashi | Design and synthesis of new tripeptide-type SARS-CoV 3CL protease inhibitors containing an electrophilic arylketone moiety. |
| 001277 (2013) |
Jon Jacobs ; Valerie Grum-Tokars ; Ya Zhou ; Mark Turlington ; S Adrian Saldanha ; Peter Chase ; Aimee Eggler ; Eric S. Dawson ; Yahira M. Baez-Santos ; Sakshi Tomar ; Anna M. Mielech ; Susan C. Baker ; Craig W. Lindsley ; Peter Hodder ; Andrew Mesecar ; Shaun R. Stauffer | Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV) 3CL protease. |
| 001394 (2012) |
Thi Thanh Hanh Nguyen ; Hye-Jin Woo ; Hee-Kyoung Kang ; Van Dao Nguyen ; Young-Min Kim ; Do-Won Kim ; Sul-Ah Ahn ; Yongmei Xia ; Doman Kim | Flavonoid-mediated inhibition of SARS coronavirus 3C-like protease expressed in Pichia pastoris. |
| 001410 (2012) |
Hyun Lee ; Jaime Torres ; Lena Truong ; Rima Chaudhuri ; Anuradha Mittal ; Michael E. Johnson | Reducing agents affect inhibitory activities of compounds: results from multiple drug targets. |
| 001449 (2011) |
Sheila M. Pimentel-Elardo ; Verena Buback ; Tobias A M. Gulder ; Tim S. Bugni ; Jason Reppart ; Gerhard Bringmann ; Chris M. Ireland ; Tanja Schirmeister ; Ute Hentschel | New tetromycin derivatives with anti-trypanosomal and protease inhibitory activities. |
| 001453 (2011) |
Susanne Pfefferle ; Julia Schöpf ; Manfred Kögl ; Caroline C. Friedel ; Marcel A. Müller ; Javier Carbajo-Lozoya ; Thorsten Stellberger ; Ekatarina Von Dall'Armi ; Petra Herzog ; Stefan Kallies ; Daniela Niemeyer ; Vanessa Ditt ; Thomas Kuri ; Roland Züst ; Ksenia Pumpor ; Rolf Hilgenfeld ; Frank Schwarz ; Ralf Zimmer ; Imke Steffen ; Friedemann Weber ; Volker Thiel ; Georg Herrler ; Heinz-Jürgen Thiel ; Christel Schwegmann-Wessels ; Stefan Pöhlmann ; Jürgen Haas ; Christian Drosten ; Albrecht Von Brunn | The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors. |
| 001460 (2011) |
Rima Chaudhuri ; Sishi Tang ; Guijun Zhao ; Hui Lu ; David A. Case ; Michael E. Johnson | Comparison of SARS and NL63 papain-like protease binding sites and binding site dynamics: inhibitor design implications. |
| 001469 (2011) |
R. Ramajayam ; Kian-Pin Tan ; Po-Huang Liang | Recent development of 3C and 3CL protease inhibitors for anti-coronavirus and anti-picornavirus drug discovery. |
| 001508 (2011) |
Prasenjit Mukherjee ; Falgun Shah ; Prashant Desai ; Mitchell Avery | Inhibitors of SARS-3CLpro: virtual screening, biological evaluation, and molecular dynamics simulation studies. |
| 001526 (2011) |
Thi Thanh Hanh Nguyen ; Hwa-Ja Ryu ; Se-Hoon Lee ; Soonwook Hwang ; Vincent Breton ; Joon Haeng Rhee ; Doman Kim | Virtual screening identification of novel severe acute respiratory syndrome 3C-like protease inhibitors and in vitro confirmation. |
| 001609 (2010) |
R. Ramajayam ; Kian-Pin Tan ; Hun-Ge Liu ; Po-Huang Liang | Synthesis and evaluation of pyrazolone compounds as SARS-coronavirus 3C-like protease inhibitors. |
| 001611 (2010) |
Young Bae Ryu ; Hyung Jae Jeong ; Jang Hoon Kim ; Young Min Kim ; Ji-Young Park ; Doman Kim ; Thi Thanh Hanh Nguyen ; Su-Jin Park ; Jong Sun Chang ; Ki Hun Park ; Mun-Chual Rho ; Woo Song Lee | Biflavonoids from Torreya nucifera displaying SARS-CoV 3CL(pro) inhibition. |
