SrasV1, PubMed, Corpus, bibRecord, 003005

Profile of antibodies to the nucleocapsid protein of the severe acute respiratory syndrome (SARS)-associated coronavirus in probable SARS patients.

Identifieur interne : 003005 ( PubMed/Corpus ); précédent : 003004; suivant : 003006

Profile of antibodies to the nucleocapsid protein of the severe acute respiratory syndrome (SARS)-associated coronavirus in probable SARS patients.

Auteurs : Xuan Liu ; Yulin Shi ; Ping Li ; Linhai Li ; Yanping Yi ; Qingjun Ma ; Cheng Cao

Source :

Clinical and diagnostic laboratory immunology [ 1071-412X ] ; 2004.

RBID : pubmed:14715574

English descriptors

KwdEn :
- Adult, Antibodies, Viral (blood), Case-Control Studies, Child, Enzyme-Linked Immunosorbent Assay, Humans, Nucleocapsid Proteins (immunology), SARS Virus (immunology), Severe Acute Respiratory Syndrome (diagnosis), Severe Acute Respiratory Syndrome (immunology), Time Factors.
MESH :
- chemical , blood : Antibodies, Viral.
- chemical , immunology : Nucleocapsid Proteins.
- diagnosis : Severe Acute Respiratory Syndrome.
- immunology : SARS Virus, Severe Acute Respiratory Syndrome.
- Adult, Case-Control Studies, Child, Enzyme-Linked Immunosorbent Assay, Humans, Time Factors.

Abstract

Profiles of antibodies to the nucleocapsid protein of the severe acute respiratory syndrome (SARS)-associated coronavirus in 445 probable SARS patients and 3,749 healthy people or non-SARS patients were analyzed by antigen-capturing enzyme-linked immunosorbent assay. Antinucleocapsid antibodies were elucidated in 17.5% of the probable SARS patients 1 to 7 days after the onset of symptoms and in 80% of the patients 8 to 14 days after the onset. About 90% of the probable SARS patients were positive 15 or more days after illness. Antibody titers increased up to 70 days, and high antibody titers were maintained at least for another 3 months. Of the healthy people and non-SARS patients, only seven (0.187%) were weakly positive.

DOI: 10.1128/cdli.11.1.227-228.2004
PubMed: 14715574

Links to Exploration step

pubmed:14715574

Le document en format XML

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<author><name sortKey="Liu, Xuan" sort="Liu, Xuan" uniqKey="Liu X" first="Xuan" last="Liu">Xuan Liu</name>
<affiliation><nlm:affiliation>Beijing Institute of Biotechnology, Beijing 100850, Peoples Republic of China.</nlm:affiliation>
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<author><name sortKey="Shi, Yulin" sort="Shi, Yulin" uniqKey="Shi Y" first="Yulin" last="Shi">Yulin Shi</name>
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<author><name sortKey="Li, Ping" sort="Li, Ping" uniqKey="Li P" first="Ping" last="Li">Ping Li</name>
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<author><name sortKey="Li, Linhai" sort="Li, Linhai" uniqKey="Li L" first="Linhai" last="Li">Linhai Li</name>
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<author><name sortKey="Yi, Yanping" sort="Yi, Yanping" uniqKey="Yi Y" first="Yanping" last="Yi">Yanping Yi</name>
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<author><name sortKey="Ma, Qingjun" sort="Ma, Qingjun" uniqKey="Ma Q" first="Qingjun" last="Ma">Qingjun Ma</name>
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<author><name sortKey="Cao, Cheng" sort="Cao, Cheng" uniqKey="Cao C" first="Cheng" last="Cao">Cheng Cao</name>
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<front><div type="abstract" xml:lang="en">Profiles of antibodies to the nucleocapsid protein of the severe acute respiratory syndrome (SARS)-associated coronavirus in 445 probable SARS patients and 3,749 healthy people or non-SARS patients were analyzed by antigen-capturing enzyme-linked immunosorbent assay. Antinucleocapsid antibodies were elucidated in 17.5% of the probable SARS patients 1 to 7 days after the onset of symptoms and in 80% of the patients 8 to 14 days after the onset. About 90% of the probable SARS patients were positive 15 or more days after illness. Antibody titers increased up to 70 days, and high antibody titers were maintained at least for another 3 months. Of the healthy people and non-SARS patients, only seven (0.187%) were weakly positive.</div>
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Profile of antibodies to the nucleocapsid protein of the severe acute respiratory syndrome (SARS)-associated coronavirus in probable SARS patients.

Profile of antibodies to the nucleocapsid protein of the severe acute respiratory syndrome (SARS)-associated coronavirus in probable SARS patients.

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

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