Radiological and pulmonary function outcomes of children with SARS.
Identifieur interne : 002A73 ( PubMed/Corpus ); précédent : 002A72; suivant : 002A74Radiological and pulmonary function outcomes of children with SARS.
Auteurs : A M Li ; H K So ; W. Chu ; P C Ng ; K L Hon ; W K Chiu ; C W Leung ; Y S Yau ; W K Mo ; T F FokSource :
- Pediatric pulmonology [ 8755-6863 ] ; 2004.
English descriptors
- KwdEn :
- Adolescent, Child, Female, Follow-Up Studies, Humans, Lung (diagnostic imaging), Lung (physiopathology), Male, Respiratory Function Tests, SARS Virus, Severe Acute Respiratory Syndrome (diagnostic imaging), Severe Acute Respiratory Syndrome (physiopathology), Severity of Illness Index, Time Factors, Tomography, X-Ray Computed, Treatment Outcome.
- MESH :
- diagnostic imaging : Lung, Severe Acute Respiratory Syndrome.
- physiopathology : Lung, Severe Acute Respiratory Syndrome.
- Adolescent, Child, Female, Follow-Up Studies, Humans, Male, Respiratory Function Tests, SARS Virus, Severity of Illness Index, Time Factors, Tomography, X-Ray Computed, Treatment Outcome.
Abstract
We examined the radiological and pulmonary function outcomes of children affected with severe acute respiratory syndrome (SARS) at 6 months from diagnosis. Twenty-one female and 26 male Chinese patients (median age, 13.6 years; interquartile range, 9.9-16.0) were studied. In each subject, high-resolution computed tomography (HRCT) of the thorax and pulmonary function were assessed. All children were asymptomatic and had a normal clinical examination. Mild pulmonary abnormalities were detected on HRCT in 16 (34.0%) subjects, including residual ground-glass opacification (n = 5), air trapping (n = 8), and a combination of ground-glass changes and air trapping (n = 3). The need for oxygen supplementation (P = 0.02) and lymphopenia during the course of illness (P = 0.012) were significant risk factors in predicting abnormal HRCT. There were no significant lung function differences between those with and without HRCT abnormalities. Despite complete clinical resolution, a considerable proportion of children affected with SARS had abnormal HRCT findings at 6 months. These abnormalities were more prevalent in those with severe disease. It is important that careful follow-up be carried out to assess the clinical significance and persistence of such abnormalities.
DOI: 10.1002/ppul.20078
PubMed: 15514972
Links to Exploration step
pubmed:15514972Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Radiological and pulmonary function outcomes of children with SARS.</title>
<author><name sortKey="Li, A M" sort="Li, A M" uniqKey="Li A" first="A M" last="Li">A M Li</name>
<affiliation><nlm:affiliation>Department of Paediatrics, Prince of Wales Hospital, Shatin Hong Kong.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="So, H K" sort="So, H K" uniqKey="So H" first="H K" last="So">H K So</name>
</author>
<author><name sortKey="Chu, W" sort="Chu, W" uniqKey="Chu W" first="W" last="Chu">W. Chu</name>
</author>
<author><name sortKey="Ng, P C" sort="Ng, P C" uniqKey="Ng P" first="P C" last="Ng">P C Ng</name>
</author>
<author><name sortKey="Hon, K L" sort="Hon, K L" uniqKey="Hon K" first="K L" last="Hon">K L Hon</name>
</author>
<author><name sortKey="Chiu, W K" sort="Chiu, W K" uniqKey="Chiu W" first="W K" last="Chiu">W K Chiu</name>
</author>
<author><name sortKey="Leung, C W" sort="Leung, C W" uniqKey="Leung C" first="C W" last="Leung">C W Leung</name>
</author>
<author><name sortKey="Yau, Y S" sort="Yau, Y S" uniqKey="Yau Y" first="Y S" last="Yau">Y S Yau</name>
</author>
<author><name sortKey="Mo, W K" sort="Mo, W K" uniqKey="Mo W" first="W K" last="Mo">W K Mo</name>
</author>
<author><name sortKey="Fok, T F" sort="Fok, T F" uniqKey="Fok T" first="T F" last="Fok">T F Fok</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2004">2004</date>
<idno type="RBID">pubmed:15514972</idno>
<idno type="pmid">15514972</idno>
<idno type="doi">10.1002/ppul.20078</idno>
<idno type="wicri:Area/PubMed/Corpus">002A73</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002A73</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Radiological and pulmonary function outcomes of children with SARS.</title>
<author><name sortKey="Li, A M" sort="Li, A M" uniqKey="Li A" first="A M" last="Li">A M Li</name>
<affiliation><nlm:affiliation>Department of Paediatrics, Prince of Wales Hospital, Shatin Hong Kong.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="So, H K" sort="So, H K" uniqKey="So H" first="H K" last="So">H K So</name>
</author>
<author><name sortKey="Chu, W" sort="Chu, W" uniqKey="Chu W" first="W" last="Chu">W. Chu</name>
</author>
<author><name sortKey="Ng, P C" sort="Ng, P C" uniqKey="Ng P" first="P C" last="Ng">P C Ng</name>
</author>
<author><name sortKey="Hon, K L" sort="Hon, K L" uniqKey="Hon K" first="K L" last="Hon">K L Hon</name>
</author>
<author><name sortKey="Chiu, W K" sort="Chiu, W K" uniqKey="Chiu W" first="W K" last="Chiu">W K Chiu</name>
</author>
<author><name sortKey="Leung, C W" sort="Leung, C W" uniqKey="Leung C" first="C W" last="Leung">C W Leung</name>
</author>
<author><name sortKey="Yau, Y S" sort="Yau, Y S" uniqKey="Yau Y" first="Y S" last="Yau">Y S Yau</name>
</author>
<author><name sortKey="Mo, W K" sort="Mo, W K" uniqKey="Mo W" first="W K" last="Mo">W K Mo</name>
</author>
<author><name sortKey="Fok, T F" sort="Fok, T F" uniqKey="Fok T" first="T F" last="Fok">T F Fok</name>
</author>
</analytic>
<series><title level="j">Pediatric pulmonology</title>
<idno type="ISSN">8755-6863</idno>
<imprint><date when="2004" type="published">2004</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Child</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Lung (diagnostic imaging)</term>
<term>Lung (physiopathology)</term>
<term>Male</term>
<term>Respiratory Function Tests</term>
<term>SARS Virus</term>
<term>Severe Acute Respiratory Syndrome (diagnostic imaging)</term>
<term>Severe Acute Respiratory Syndrome (physiopathology)</term>
<term>Severity of Illness Index</term>
<term>Time Factors</term>
<term>Tomography, X-Ray Computed</term>
<term>Treatment Outcome</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Lung</term>
<term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Lung</term>
<term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Child</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Male</term>
<term>Respiratory Function Tests</term>
<term>SARS Virus</term>
<term>Severity of Illness Index</term>
<term>Time Factors</term>
<term>Tomography, X-Ray Computed</term>
<term>Treatment Outcome</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">We examined the radiological and pulmonary function outcomes of children affected with severe acute respiratory syndrome (SARS) at 6 months from diagnosis. Twenty-one female and 26 male Chinese patients (median age, 13.6 years; interquartile range, 9.9-16.0) were studied. In each subject, high-resolution computed tomography (HRCT) of the thorax and pulmonary function were assessed. All children were asymptomatic and had a normal clinical examination. Mild pulmonary abnormalities were detected on HRCT in 16 (34.0%) subjects, including residual ground-glass opacification (n = 5), air trapping (n = 8), and a combination of ground-glass changes and air trapping (n = 3). The need for oxygen supplementation (P = 0.02) and lymphopenia during the course of illness (P = 0.012) were significant risk factors in predicting abnormal HRCT. There were no significant lung function differences between those with and without HRCT abnormalities. Despite complete clinical resolution, a considerable proportion of children affected with SARS had abnormal HRCT findings at 6 months. These abnormalities were more prevalent in those with severe disease. It is important that careful follow-up be carried out to assess the clinical significance and persistence of such abnormalities.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">15514972</PMID>
<DateCompleted><Year>2005</Year>
<Month>03</Month>
<Day>29</Day>
</DateCompleted>
<DateRevised><Year>2016</Year>
<Month>11</Month>
<Day>24</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">8755-6863</ISSN>
<JournalIssue CitedMedium="Print"><Volume>38</Volume>
<Issue>6</Issue>
<PubDate><Year>2004</Year>
<Month>Dec</Month>
</PubDate>
</JournalIssue>
<Title>Pediatric pulmonology</Title>
<ISOAbbreviation>Pediatr. Pulmonol.</ISOAbbreviation>
</Journal>
<ArticleTitle>Radiological and pulmonary function outcomes of children with SARS.</ArticleTitle>
<Pagination><MedlinePgn>427-33</MedlinePgn>
</Pagination>
<Abstract><AbstractText>We examined the radiological and pulmonary function outcomes of children affected with severe acute respiratory syndrome (SARS) at 6 months from diagnosis. Twenty-one female and 26 male Chinese patients (median age, 13.6 years; interquartile range, 9.9-16.0) were studied. In each subject, high-resolution computed tomography (HRCT) of the thorax and pulmonary function were assessed. All children were asymptomatic and had a normal clinical examination. Mild pulmonary abnormalities were detected on HRCT in 16 (34.0%) subjects, including residual ground-glass opacification (n = 5), air trapping (n = 8), and a combination of ground-glass changes and air trapping (n = 3). The need for oxygen supplementation (P = 0.02) and lymphopenia during the course of illness (P = 0.012) were significant risk factors in predicting abnormal HRCT. There were no significant lung function differences between those with and without HRCT abnormalities. Despite complete clinical resolution, a considerable proportion of children affected with SARS had abnormal HRCT findings at 6 months. These abnormalities were more prevalent in those with severe disease. It is important that careful follow-up be carried out to assess the clinical significance and persistence of such abnormalities.</AbstractText>
<CopyrightInformation>Copyright 2004 Wiley-Liss, Inc.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Li</LastName>
<ForeName>A M</ForeName>
<Initials>AM</Initials>
<AffiliationInfo><Affiliation>Department of Paediatrics, Prince of Wales Hospital, Shatin Hong Kong.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>So</LastName>
<ForeName>H K</ForeName>
<Initials>HK</Initials>
</Author>
<Author ValidYN="Y"><LastName>Chu</LastName>
<ForeName>W</ForeName>
<Initials>W</Initials>
</Author>
<Author ValidYN="Y"><LastName>Ng</LastName>
<ForeName>P C</ForeName>
<Initials>PC</Initials>
</Author>
<Author ValidYN="Y"><LastName>Hon</LastName>
<ForeName>K L</ForeName>
<Initials>KL</Initials>
</Author>
<Author ValidYN="Y"><LastName>Chiu</LastName>
<ForeName>W K</ForeName>
<Initials>WK</Initials>
</Author>
<Author ValidYN="Y"><LastName>Leung</LastName>
<ForeName>C W</ForeName>
<Initials>CW</Initials>
</Author>
<Author ValidYN="Y"><LastName>Yau</LastName>
<ForeName>Y S</ForeName>
<Initials>YS</Initials>
</Author>
<Author ValidYN="Y"><LastName>Mo</LastName>
<ForeName>W K</ForeName>
<Initials>WK</Initials>
</Author>
<Author ValidYN="Y"><LastName>Fok</LastName>
<ForeName>T F</ForeName>
<Initials>TF</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Pediatr Pulmonol</MedlineTA>
<NlmUniqueID>8510590</NlmUniqueID>
<ISSNLinking>1099-0496</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005500" MajorTopicYN="N">Follow-Up Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008168" MajorTopicYN="N">Lung</DescriptorName>
<QualifierName UI="Q000000981" MajorTopicYN="Y">diagnostic imaging</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012129" MajorTopicYN="N">Respiratory Function Tests</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D045473" MajorTopicYN="Y">SARS Virus</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D045169" MajorTopicYN="N">Severe Acute Respiratory Syndrome</DescriptorName>
<QualifierName UI="Q000000981" MajorTopicYN="Y">diagnostic imaging</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012720" MajorTopicYN="N">Severity of Illness Index</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014057" MajorTopicYN="N">Tomography, X-Ray Computed</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016896" MajorTopicYN="N">Treatment Outcome</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2004</Year>
<Month>10</Month>
<Day>30</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2005</Year>
<Month>3</Month>
<Day>30</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2004</Year>
<Month>10</Month>
<Day>30</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">15514972</ArticleId>
<ArticleId IdType="doi">10.1002/ppul.20078</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002A73 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 002A73 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= SrasV1 |flux= PubMed |étape= Corpus |type= RBID |clé= pubmed:15514972 |texte= Radiological and pulmonary function outcomes of children with SARS. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:15514972" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \ | NlmPubMed2Wicri -a SrasV1
![]() | This area was generated with Dilib version V0.6.33. | ![]() |