SrasV1, PubMed, Corpus, bibRecord, 002806

SARS-CoV infection was from at least two origins in the Taiwan area.

Identifieur interne : 002806 ( PubMed/Corpus ); précédent : 002805; suivant : 002807

SARS-CoV infection was from at least two origins in the Taiwan area.

Auteurs : Mu-Chin Shih ; Konan Peck ; Wen-Ling Chan ; Yen-Ping Chu ; Jui-Chang Chen ; Chang-Hai Tsai ; Jan-Gowth Chang

Source :

Intervirology [ 0300-5526 ] ; 2005.

RBID : pubmed:15812185

English descriptors

KwdEn :
- Adult, DNA, Complementary (chemistry), DNA, Complementary (isolation & purification), Female, Humans, Male, Middle Aged, Molecular Epidemiology, Molecular Sequence Data, Phylogeny, Point Mutation, Polymerase Chain Reaction, RNA, Viral (genetics), RNA, Viral (isolation & purification), RNA, Viral (metabolism), Reverse Transcriptase Polymerase Chain Reaction, SARS Virus (genetics), SARS Virus (isolation & purification), Sequence Analysis, DNA, Sequence Deletion, Severe Acute Respiratory Syndrome (epidemiology), Severe Acute Respiratory Syndrome (virology), Taiwan.
MESH :
- chemical , chemistry : DNA, Complementary.
- chemical , genetics : RNA, Viral.
- chemical , isolation & purification : DNA, Complementary, RNA, Viral.
- chemical , metabolism : RNA, Viral.
- geographic : Taiwan.
- epidemiology : Severe Acute Respiratory Syndrome.
- genetics : SARS Virus.
- isolation & purification : SARS Virus.
- virology : Severe Acute Respiratory Syndrome.
- Adult, Female, Humans, Male, Middle Aged, Molecular Epidemiology, Molecular Sequence Data, Phylogeny, Point Mutation, Polymerase Chain Reaction, Reverse Transcriptase Polymerase Chain Reaction, Sequence Analysis, DNA, Sequence Deletion.

Abstract

Severe acute respiratory syndrome (SARS) is caused by a new coronavirus. Genomic sequence analysis will provide the molecular epidemiology and help to develop vaccines.

DOI: 10.1159/000081739
PubMed: 15812185

Links to Exploration step

pubmed:15812185

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">SARS-CoV infection was from at least two origins in the Taiwan area.</title>
<author><name sortKey="Shih, Mu Chin" sort="Shih, Mu Chin" uniqKey="Shih M" first="Mu-Chin" last="Shih">Mu-Chin Shih</name>
<affiliation><nlm:affiliation>Department of Molecular Medicine, China Medical University Hospital, Taichung, Taiwan.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Peck, Konan" sort="Peck, Konan" uniqKey="Peck K" first="Konan" last="Peck">Konan Peck</name>
</author>
<author><name sortKey="Chan, Wen Ling" sort="Chan, Wen Ling" uniqKey="Chan W" first="Wen-Ling" last="Chan">Wen-Ling Chan</name>
</author>
<author><name sortKey="Chu, Yen Ping" sort="Chu, Yen Ping" uniqKey="Chu Y" first="Yen-Ping" last="Chu">Yen-Ping Chu</name>
</author>
<author><name sortKey="Chen, Jui Chang" sort="Chen, Jui Chang" uniqKey="Chen J" first="Jui-Chang" last="Chen">Jui-Chang Chen</name>
</author>
<author><name sortKey="Tsai, Chang Hai" sort="Tsai, Chang Hai" uniqKey="Tsai C" first="Chang-Hai" last="Tsai">Chang-Hai Tsai</name>
</author>
<author><name sortKey="Chang, Jan Gowth" sort="Chang, Jan Gowth" uniqKey="Chang J" first="Jan-Gowth" last="Chang">Jan-Gowth Chang</name>
</author>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">SARS-CoV infection was from at least two origins in the Taiwan area.</title>
<author><name sortKey="Shih, Mu Chin" sort="Shih, Mu Chin" uniqKey="Shih M" first="Mu-Chin" last="Shih">Mu-Chin Shih</name>
<affiliation><nlm:affiliation>Department of Molecular Medicine, China Medical University Hospital, Taichung, Taiwan.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Peck, Konan" sort="Peck, Konan" uniqKey="Peck K" first="Konan" last="Peck">Konan Peck</name>
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<author><name sortKey="Chan, Wen Ling" sort="Chan, Wen Ling" uniqKey="Chan W" first="Wen-Ling" last="Chan">Wen-Ling Chan</name>
</author>
<author><name sortKey="Chu, Yen Ping" sort="Chu, Yen Ping" uniqKey="Chu Y" first="Yen-Ping" last="Chu">Yen-Ping Chu</name>
</author>
<author><name sortKey="Chen, Jui Chang" sort="Chen, Jui Chang" uniqKey="Chen J" first="Jui-Chang" last="Chen">Jui-Chang Chen</name>
</author>
<author><name sortKey="Tsai, Chang Hai" sort="Tsai, Chang Hai" uniqKey="Tsai C" first="Chang-Hai" last="Tsai">Chang-Hai Tsai</name>
</author>
<author><name sortKey="Chang, Jan Gowth" sort="Chang, Jan Gowth" uniqKey="Chang J" first="Jan-Gowth" last="Chang">Jan-Gowth Chang</name>
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</analytic>
<series><title level="j">Intervirology</title>
<idno type="ISSN">0300-5526</idno>
<imprint><date when="2005" type="published">2005</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>DNA, Complementary (chemistry)</term>
<term>DNA, Complementary (isolation & purification)</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Molecular Epidemiology</term>
<term>Molecular Sequence Data</term>
<term>Phylogeny</term>
<term>Point Mutation</term>
<term>Polymerase Chain Reaction</term>
<term>RNA, Viral (genetics)</term>
<term>RNA, Viral (isolation & purification)</term>
<term>RNA, Viral (metabolism)</term>
<term>Reverse Transcriptase Polymerase Chain Reaction</term>
<term>SARS Virus (genetics)</term>
<term>SARS Virus (isolation & purification)</term>
<term>Sequence Analysis, DNA</term>
<term>Sequence Deletion</term>
<term>Severe Acute Respiratory Syndrome (epidemiology)</term>
<term>Severe Acute Respiratory Syndrome (virology)</term>
<term>Taiwan</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>DNA, Complementary</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>RNA, Viral</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="isolation & purification" xml:lang="en"><term>DNA, Complementary</term>
<term>RNA, Viral</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>RNA, Viral</term>
</keywords>
<keywords scheme="MESH" type="geographic" xml:lang="en"><term>Taiwan</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Molecular Epidemiology</term>
<term>Molecular Sequence Data</term>
<term>Phylogeny</term>
<term>Point Mutation</term>
<term>Polymerase Chain Reaction</term>
<term>Reverse Transcriptase Polymerase Chain Reaction</term>
<term>Sequence Analysis, DNA</term>
<term>Sequence Deletion</term>
</keywords>
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<front><div type="abstract" xml:lang="en">Severe acute respiratory syndrome (SARS) is caused by a new coronavirus. Genomic sequence analysis will provide the molecular epidemiology and help to develop vaccines.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">15812185</PMID>
<DateCompleted><Year>2005</Year>
<Month>08</Month>
<Day>18</Day>
</DateCompleted>
<DateRevised><Year>2011</Year>
<Month>03</Month>
<Day>09</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0300-5526</ISSN>
<JournalIssue CitedMedium="Print"><Volume>48</Volume>
<Issue>2-3</Issue>
<PubDate><Year>2005</Year>
</PubDate>
</JournalIssue>
<Title>Intervirology</Title>
<ISOAbbreviation>Intervirology</ISOAbbreviation>
</Journal>
<ArticleTitle>SARS-CoV infection was from at least two origins in the Taiwan area.</ArticleTitle>
<Pagination><MedlinePgn>124-32</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">Severe acute respiratory syndrome (SARS) is caused by a new coronavirus. Genomic sequence analysis will provide the molecular epidemiology and help to develop vaccines.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">We developed a rapid method to amplify and sequence the whole SARS-CoV genome from clinical specimens. The technique employed one-step multiplex RT-PCR to amplify the whole SARS-CoV genome, and then nested PCR was performed to amplify a 2-kb region separately. The PCR products were sequenced.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">We sequenced the genomes of SARS-CoV from 3 clinical specimens obtained in Taiwan. The sequences were similar to those reported by other groups, except that 17 single nucleotide variations and two 2-nucleotide deletions, and a 1-nucleotide deletion were found. All the variations in the clinical specimens did not alter the amino acid sequence. Of these 17 sequenced variants, two loci (positions 26203 and 27812) were segregated together as a specific genotype - T:T or C:C. Phylogenetic analysis showed two major clusters of SARS patients in Taiwan.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">We developed a very economical and rapid method to sequence the whole genome of SARS-CoV, which can avoid cultural influence. From our results, SARS patients in Taiwan may be infected from two different origins.</AbstractText>
<CopyrightInformation>Copyright (c) 2005 S. Karger AG, Basel.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Shih</LastName>
<ForeName>Mu-Chin</ForeName>
<Initials>MC</Initials>
<AffiliationInfo><Affiliation>Department of Molecular Medicine, China Medical University Hospital, Taichung, Taiwan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Peck</LastName>
<ForeName>Konan</ForeName>
<Initials>K</Initials>
</Author>
<Author ValidYN="Y"><LastName>Chan</LastName>
<ForeName>Wen-Ling</ForeName>
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<Author ValidYN="Y"><LastName>Chu</LastName>
<ForeName>Yen-Ping</ForeName>
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<Author ValidYN="Y"><LastName>Chen</LastName>
<ForeName>Jui-Chang</ForeName>
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<Author ValidYN="Y"><LastName>Tsai</LastName>
<ForeName>Chang-Hai</ForeName>
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<Author ValidYN="Y"><LastName>Chang</LastName>
<ForeName>Jan-Gowth</ForeName>
<Initials>JG</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<DataBankList CompleteYN="Y"><DataBank><DataBankName>GENBANK</DataBankName>
<AccessionNumberList><AccessionNumber>AY338174</AccessionNumber>
<AccessionNumber>AY338175</AccessionNumber>
<AccessionNumber>AY348314</AccessionNumber>
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</DataBank>
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<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
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<MedlineJournalInfo><Country>Switzerland</Country>
<MedlineTA>Intervirology</MedlineTA>
<NlmUniqueID>0364265</NlmUniqueID>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
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<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
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<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
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<MeshHeading><DescriptorName UI="D017720" MajorTopicYN="Y">Molecular Epidemiology</DescriptorName>
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<MeshHeading><DescriptorName UI="D008969" MajorTopicYN="N">Molecular Sequence Data</DescriptorName>
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<MeshHeading><DescriptorName UI="D010802" MajorTopicYN="N">Phylogeny</DescriptorName>
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<MeshHeading><DescriptorName UI="D017354" MajorTopicYN="N">Point Mutation</DescriptorName>
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<MeshHeading><DescriptorName UI="D020133" MajorTopicYN="N">Reverse Transcriptase Polymerase Chain Reaction</DescriptorName>
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</MeshHeading>
<MeshHeading><DescriptorName UI="D017384" MajorTopicYN="N">Sequence Deletion</DescriptorName>
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<MeshHeading><DescriptorName UI="D013624" MajorTopicYN="N" Type="Geographic">Taiwan</DescriptorName>
</MeshHeading>
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<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2004</Year>
<Month>02</Month>
<Day>19</Day>
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<PubMedPubDate PubStatus="accepted"><Year>2004</Year>
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SARS-CoV infection was from at least two origins in the Taiwan area.

SARS-CoV infection was from at least two origins in the Taiwan area.

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki