Intervention measures, turning point, and reproduction number for dengue, Singapore, 2005.
Identifieur interne : 001982 ( PubMed/Corpus ); précédent : 001981; suivant : 001983Intervention measures, turning point, and reproduction number for dengue, Singapore, 2005.
Auteurs : Ying-Hen Hsieh ; Stefan MaSource :
- The American journal of tropical medicine and hygiene [ 1476-1645 ] ; 2009.
English descriptors
- KwdEn :
- MESH :
- geographic , epidemiology : Singapore.
- epidemiology : Dengue.
- growth & development : Dengue Virus.
- methods : Disease Notification.
- physiology : Dengue Virus.
- prevention & control : Dengue.
- transmission : Dengue.
- Disease Outbreaks, Humans, Risk Factors, Seasons, Tropical Climate.
Abstract
The 2005 dengue outbreak in Singapore cumulated in > 14,000 cases and 27 reported dengue deaths. We fit the single-phase Richards model to weekly dengue notification numbers to detect the turning point for the outbreak, which enables us to study the impact of intervention measures relating to the turning point. The results indicate that turning point had most likely occurred in late August or early September, before large-scale intervention measures were implemented. The "initial" reproduction number for the outbreak is estimated to be ~1.89-2.23 (95% confidence interval: 1.15-3.00). One of the lessons learned from the 2003 severe acute respiratory syndrome (SARS) outbreak is that multiple phases of outbreak were observed in some affected countries when efforts to intensify intervention or to sustain vigilance were compromised. Intensive and continuing efforts in the implementation of control measures are essential in reducing further dengue occurrences during any resurgence of dengue.
PubMed: 19141842
Links to Exploration step
pubmed:19141842Le document en format XML
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<affiliation><nlm:affiliation>Department of Public Health and Biostatistics Center, China Medical University, Taichung, Taiwan. hsieh@mail.cmu.edu.tw</nlm:affiliation>
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<author><name sortKey="Ma, Stefan" sort="Ma, Stefan" uniqKey="Ma S" first="Stefan" last="Ma">Stefan Ma</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Dengue (epidemiology)</term>
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<term>Dengue Virus (growth & development)</term>
<term>Dengue Virus (physiology)</term>
<term>Disease Notification (methods)</term>
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<term>Humans</term>
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<term>Tropical Climate</term>
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<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Singapore</term>
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<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Dengue</term>
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<keywords scheme="MESH" qualifier="growth & development" xml:lang="en"><term>Dengue Virus</term>
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<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Dengue Virus</term>
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<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Dengue</term>
</keywords>
<keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Dengue</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Disease Outbreaks</term>
<term>Humans</term>
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<term>Seasons</term>
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<front><div type="abstract" xml:lang="en">The 2005 dengue outbreak in Singapore cumulated in > 14,000 cases and 27 reported dengue deaths. We fit the single-phase Richards model to weekly dengue notification numbers to detect the turning point for the outbreak, which enables us to study the impact of intervention measures relating to the turning point. The results indicate that turning point had most likely occurred in late August or early September, before large-scale intervention measures were implemented. The "initial" reproduction number for the outbreak is estimated to be ~1.89-2.23 (95% confidence interval: 1.15-3.00). One of the lessons learned from the 2003 severe acute respiratory syndrome (SARS) outbreak is that multiple phases of outbreak were observed in some affected countries when efforts to intensify intervention or to sustain vigilance were compromised. Intensive and continuing efforts in the implementation of control measures are essential in reducing further dengue occurrences during any resurgence of dengue.</div>
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<Title>The American journal of tropical medicine and hygiene</Title>
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<ArticleTitle>Intervention measures, turning point, and reproduction number for dengue, Singapore, 2005.</ArticleTitle>
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<Abstract><AbstractText>The 2005 dengue outbreak in Singapore cumulated in > 14,000 cases and 27 reported dengue deaths. We fit the single-phase Richards model to weekly dengue notification numbers to detect the turning point for the outbreak, which enables us to study the impact of intervention measures relating to the turning point. The results indicate that turning point had most likely occurred in late August or early September, before large-scale intervention measures were implemented. The "initial" reproduction number for the outbreak is estimated to be ~1.89-2.23 (95% confidence interval: 1.15-3.00). One of the lessons learned from the 2003 severe acute respiratory syndrome (SARS) outbreak is that multiple phases of outbreak were observed in some affected countries when efforts to intensify intervention or to sustain vigilance were compromised. Intensive and continuing efforts in the implementation of control measures are essential in reducing further dengue occurrences during any resurgence of dengue.</AbstractText>
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<MeshHeading><DescriptorName UI="D012846" MajorTopicYN="N" Type="Geographic">Singapore</DescriptorName>
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