The antiviral action of common household disinfectants and antiseptics against murine hepatitis virus, a potential surrogate for SARS coronavirus.
Identifieur interne : 001844 ( PubMed/Corpus ); précédent : 001843; suivant : 001845The antiviral action of common household disinfectants and antiseptics against murine hepatitis virus, a potential surrogate for SARS coronavirus.
Auteurs : Christine Dellanno ; Quinn Vega ; Diane BoesenbergSource :
- American journal of infection control [ 1527-3296 ] ; 2009.
English descriptors
- KwdEn :
- Cells, Cultured, Disinfectants (pharmacology), Disinfection (methods), Dose-Response Relationship, Drug, Environmental Microbiology, Humans, Microbial Sensitivity Tests, Murine hepatitis virus (drug effects), Pinus (chemistry), Plant Oils (pharmacology), Quaternary Ammonium Compounds (pharmacology), SARS Virus (drug effects), Severe Acute Respiratory Syndrome (prevention & control), Severe Acute Respiratory Syndrome (virology), Sodium Hypochlorite (pharmacology), Triclosan (pharmacology), Virus Inactivation (drug effects), Xylenes (pharmacology).
- MESH :
- chemical , pharmacology : Disinfectants, Plant Oils, Quaternary Ammonium Compounds, Sodium Hypochlorite, Triclosan, Xylenes.
- chemistry : Pinus.
- drug effects : Murine hepatitis virus, SARS Virus, Virus Inactivation.
- methods : Disinfection.
- prevention & control : Severe Acute Respiratory Syndrome.
- virology : Severe Acute Respiratory Syndrome.
- Cells, Cultured, Dose-Response Relationship, Drug, Environmental Microbiology, Humans, Microbial Sensitivity Tests.
Abstract
The 2003 outbreak of severe acute respiratory syndrome (SARS) infected over 8000 people and killed 774. Transmission of SARS occurred through direct and indirect contact and large droplet nuclei. The World Health Organization recommended the use of household disinfectants, which have not been previously tested against SARS coronavirus (SARS-CoV), to disinfect potentially contaminated environmental surfaces. There is a need for a surrogate test system given the limited availability of the SARS-CoV for testing and biosafety requirements necessary to safely handle it. In this study, the antiviral activity of standard household products was assayed against murine hepatitis virus (MHV), as a potential surrogate for SARS-CoV.
DOI: 10.1016/j.ajic.2009.03.012
PubMed: 19692148
Links to Exploration step
pubmed:19692148Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The antiviral action of common household disinfectants and antiseptics against murine hepatitis virus, a potential surrogate for SARS coronavirus.</title><author><name sortKey="Dellanno, Christine" sort="Dellanno, Christine" uniqKey="Dellanno C" first="Christine" last="Dellanno">Christine Dellanno</name><affiliation><nlm:affiliation>Reckitt Benckiser, Montvale, NJ 07645, USA. christine.dellanno@reckittbenckiser.com</nlm:affiliation></affiliation></author><author><name sortKey="Vega, Quinn" sort="Vega, Quinn" uniqKey="Vega Q" first="Quinn" last="Vega">Quinn Vega</name></author><author><name sortKey="Boesenberg, Diane" sort="Boesenberg, Diane" uniqKey="Boesenberg D" first="Diane" last="Boesenberg">Diane Boesenberg</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2009">2009</date><idno type="RBID">pubmed:19692148</idno><idno type="pmid">19692148</idno><idno type="doi">10.1016/j.ajic.2009.03.012</idno><idno type="wicri:Area/PubMed/Corpus">001844</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001844</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">The antiviral action of common household disinfectants and antiseptics against murine hepatitis virus, a potential surrogate for SARS coronavirus.</title><author><name sortKey="Dellanno, Christine" sort="Dellanno, Christine" uniqKey="Dellanno C" first="Christine" last="Dellanno">Christine Dellanno</name><affiliation><nlm:affiliation>Reckitt Benckiser, Montvale, NJ 07645, USA. christine.dellanno@reckittbenckiser.com</nlm:affiliation></affiliation></author><author><name sortKey="Vega, Quinn" sort="Vega, Quinn" uniqKey="Vega Q" first="Quinn" last="Vega">Quinn Vega</name></author><author><name sortKey="Boesenberg, Diane" sort="Boesenberg, Diane" uniqKey="Boesenberg D" first="Diane" last="Boesenberg">Diane Boesenberg</name></author></analytic><series><title level="j">American journal of infection control</title><idno type="eISSN">1527-3296</idno><imprint><date when="2009" type="published">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cells, Cultured</term><term>Disinfectants (pharmacology)</term><term>Disinfection (methods)</term><term>Dose-Response Relationship, Drug</term><term>Environmental Microbiology</term><term>Humans</term><term>Microbial Sensitivity Tests</term><term>Murine hepatitis virus (drug effects)</term><term>Pinus (chemistry)</term><term>Plant Oils (pharmacology)</term><term>Quaternary Ammonium Compounds (pharmacology)</term><term>SARS Virus (drug effects)</term><term>Severe Acute Respiratory Syndrome (prevention & control)</term><term>Severe Acute Respiratory Syndrome (virology)</term><term>Sodium Hypochlorite (pharmacology)</term><term>Triclosan (pharmacology)</term><term>Virus Inactivation (drug effects)</term><term>Xylenes (pharmacology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Disinfectants</term><term>Plant Oils</term><term>Quaternary Ammonium Compounds</term><term>Sodium Hypochlorite</term><term>Triclosan</term><term>Xylenes</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Pinus</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Murine hepatitis virus</term><term>SARS Virus</term><term>Virus Inactivation</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Disinfection</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Cells, Cultured</term><term>Dose-Response Relationship, Drug</term><term>Environmental Microbiology</term><term>Humans</term><term>Microbial Sensitivity Tests</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The 2003 outbreak of severe acute respiratory syndrome (SARS) infected over 8000 people and killed 774. Transmission of SARS occurred through direct and indirect contact and large droplet nuclei. The World Health Organization recommended the use of household disinfectants, which have not been previously tested against SARS coronavirus (SARS-CoV), to disinfect potentially contaminated environmental surfaces. There is a need for a surrogate test system given the limited availability of the SARS-CoV for testing and biosafety requirements necessary to safely handle it. In this study, the antiviral activity of standard household products was assayed against murine hepatitis virus (MHV), as a potential surrogate for SARS-CoV.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">19692148</PMID><DateCompleted><Year>2009</Year><Month>11</Month><Day>05</Day></DateCompleted><DateRevised><Year>2020</Year><Month>04</Month><Day>09</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1527-3296</ISSN><JournalIssue CitedMedium="Internet"><Volume>37</Volume><Issue>8</Issue><PubDate><Year>2009</Year><Month>Oct</Month></PubDate></JournalIssue><Title>American journal of infection control</Title><ISOAbbreviation>Am J Infect Control</ISOAbbreviation></Journal><ArticleTitle>The antiviral action of common household disinfectants and antiseptics against murine hepatitis virus, a potential surrogate for SARS coronavirus.</ArticleTitle><Pagination><MedlinePgn>649-52</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.ajic.2009.03.012</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">The 2003 outbreak of severe acute respiratory syndrome (SARS) infected over 8000 people and killed 774. Transmission of SARS occurred through direct and indirect contact and large droplet nuclei. The World Health Organization recommended the use of household disinfectants, which have not been previously tested against SARS coronavirus (SARS-CoV), to disinfect potentially contaminated environmental surfaces. There is a need for a surrogate test system given the limited availability of the SARS-CoV for testing and biosafety requirements necessary to safely handle it. In this study, the antiviral activity of standard household products was assayed against murine hepatitis virus (MHV), as a potential surrogate for SARS-CoV.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">A surface test method, which involves drying an amount of virus on a surface and then applying the product for a specific contact time, was used to determine the virucidal activity. The virus titers and log reductions were determined by the Reed and Muench tissue culture infective dose (TCID)50 end point method.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">When tested as directed, common household disinfectants or antiseptics, containing either 0.050% of triclosan, 0.12% of PCMX, 0.21% of sodium hypochlorite, 0.23% of pine oil, or 0.10% of a quaternary compound with 79% of ethanol, demonstrated a 3-log reduction or better against MHV without any virus recovered in a 30-second contact time.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Common household disinfectants and antiseptics were effective at inactivating MHV, a possible surrogate for SARS-CoV, from surfaces when used as directed. In an outbreak caused by novel agents, it is important to know the effectiveness of disinfectants and antiseptics to prevent or reduce the possibility of human-to-human transmission via surfaces.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Dellanno</LastName><ForeName>Christine</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Reckitt Benckiser, Montvale, NJ 07645, USA. christine.dellanno@reckittbenckiser.com</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vega</LastName><ForeName>Quinn</ForeName><Initials>Q</Initials></Author><Author ValidYN="Y"><LastName>Boesenberg</LastName><ForeName>Diane</ForeName><Initials>D</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2009</Year><Month>08</Month><Day>18</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Am J Infect Control</MedlineTA><NlmUniqueID>8004854</NlmUniqueID><ISSNLinking>0196-6553</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D004202">Disinfectants</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010938">Plant Oils</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000644">Quaternary Ammonium Compounds</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014992">Xylenes</NameOfSubstance></Chemical><Chemical><RegistryNumber>0F32U78V2Q</RegistryNumber><NameOfSubstance UI="C007027">chloroxylenol</NameOfSubstance></Chemical><Chemical><RegistryNumber>4NM5039Y5X</RegistryNumber><NameOfSubstance UI="D014260">Triclosan</NameOfSubstance></Chemical><Chemical><RegistryNumber>DY38VHM5OD</RegistryNumber><NameOfSubstance UI="D012973">Sodium Hypochlorite</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D002478" MajorTopicYN="N">Cells, Cultured</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004202" MajorTopicYN="N">Disinfectants</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004203" MajorTopicYN="N">Disinfection</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004305" MajorTopicYN="N">Dose-Response Relationship, Drug</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004783" MajorTopicYN="N">Environmental Microbiology</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008826" MajorTopicYN="N">Microbial Sensitivity Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006517" MajorTopicYN="N">Murine hepatitis virus</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D028223" MajorTopicYN="N">Pinus</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010938" MajorTopicYN="N">Plant Oils</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000644" MajorTopicYN="N">Quaternary Ammonium Compounds</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D045473" MajorTopicYN="N">SARS Virus</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D045169" MajorTopicYN="N">Severe Acute Respiratory Syndrome</DescriptorName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012973" MajorTopicYN="N">Sodium Hypochlorite</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014260" MajorTopicYN="N">Triclosan</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D038301" MajorTopicYN="N">Virus Inactivation</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014992" MajorTopicYN="N">Xylenes</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate 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IdType="pmc">PMC7132643</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Viral Immunol. 2003;16(4):461-74</Citation><ArticleIdList><ArticleId IdType="pubmed">14733734</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):6212-6</Citation><ArticleIdList><ArticleId IdType="pubmed">15073334</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Infect Genet Evol. 2003 Sep;3(3):219-25</Citation><ArticleIdList><ArticleId IdType="pubmed">14522185</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Hosp Infect. 2005 Oct;61(2):107-11</Citation><ArticleIdList><ArticleId IdType="pubmed">15923059</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12995-3000</Citation><ArticleIdList><ArticleId IdType="pubmed">14569023</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Virol. 2004 Jul;78(14):7523-7</Citation><ArticleIdList><ArticleId IdType="pubmed">15220426</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>J Hosp Infect. 2004 Apr;56 Suppl 2:S49-54</Citation><ArticleIdList><ArticleId IdType="pubmed">15110123</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>PLoS Biol. 2003 Nov;1(2):E2</Citation><ArticleIdList><ArticleId IdType="pubmed">14624234</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Emerg Infect Dis. 2004 Feb;10(2):167-70</Citation><ArticleIdList><ArticleId IdType="pubmed">15040341</ArticleId></ArticleIdList></Reference></ReferenceList><ReferenceList><Reference><Citation>Am J Infect Control. 2006 Jun;34(5):269-73</Citation><ArticleIdList><ArticleId 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