SrasV1, PubMed, Corpus, bibRecord, 001834

[Study on interaction between SARS-CoV N and MAP19].

Identifieur interne : 001834 ( PubMed/Corpus ); précédent : 001833; suivant : 001835

[Study on interaction between SARS-CoV N and MAP19].

Auteurs : Jun-Li Liu ; Cheng Cao ; Qing-Jun Ma

Source :

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology [ 1007-8738 ] ; 2009.

RBID : pubmed:19737459

English descriptors

KwdEn :
- Cell Line, Humans, Mannose-Binding Protein-Associated Serine Proteases (genetics), Mannose-Binding Protein-Associated Serine Proteases (metabolism), Nucleocapsid Proteins (genetics), Nucleocapsid Proteins (metabolism), Protein Binding, SARS Virus (genetics), SARS Virus (metabolism), Severe Acute Respiratory Syndrome (enzymology), Severe Acute Respiratory Syndrome (metabolism), Severe Acute Respiratory Syndrome (virology).
MESH :
- chemical , genetics : Mannose-Binding Protein-Associated Serine Proteases, Nucleocapsid Proteins.
- chemical , metabolism : Mannose-Binding Protein-Associated Serine Proteases, Nucleocapsid Proteins.
- enzymology : Severe Acute Respiratory Syndrome.
- genetics : SARS Virus.
- metabolism : SARS Virus, Severe Acute Respiratory Syndrome.
- virology : Severe Acute Respiratory Syndrome.
- Cell Line, Humans, Protein Binding.

Abstract

Severe acute respiratory syndrome coronavirus (SARS-CoV) is the etiological agent of SARS, an emerging disease characterized by atypical pneumonia. Using a yeast two-hybrid screen with the nucleocapsid (N)protein of SARS-CoV as a bait, the N protein was found to interact with MAP19, a non-enzymatic protein of MASP(mannan-associated serine protease). The interaction between SARS-CoV N and MAP19 would be further tested in cells in this article.

PubMed: 19737459

Links to Exploration step

pubmed:19737459

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">[Study on interaction between SARS-CoV N and MAP19].</title>
<author><name sortKey="Liu, Jun Li" sort="Liu, Jun Li" uniqKey="Liu J" first="Jun-Li" last="Liu">Jun-Li Liu</name>
<affiliation><nlm:affiliation>Institute of Biotechnology, Academy of Military Medical Sciences, Beijing 100850, China. liujunli306@sohu.com</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Cao, Cheng" sort="Cao, Cheng" uniqKey="Cao C" first="Cheng" last="Cao">Cheng Cao</name>
</author>
<author><name sortKey="Ma, Qing Jun" sort="Ma, Qing Jun" uniqKey="Ma Q" first="Qing-Jun" last="Ma">Qing-Jun Ma</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2009">2009</date>
<idno type="RBID">pubmed:19737459</idno>
<idno type="pmid">19737459</idno>
<idno type="wicri:Area/PubMed/Corpus">001834</idno>
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</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">[Study on interaction between SARS-CoV N and MAP19].</title>
<author><name sortKey="Liu, Jun Li" sort="Liu, Jun Li" uniqKey="Liu J" first="Jun-Li" last="Liu">Jun-Li Liu</name>
<affiliation><nlm:affiliation>Institute of Biotechnology, Academy of Military Medical Sciences, Beijing 100850, China. liujunli306@sohu.com</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Cao, Cheng" sort="Cao, Cheng" uniqKey="Cao C" first="Cheng" last="Cao">Cheng Cao</name>
</author>
<author><name sortKey="Ma, Qing Jun" sort="Ma, Qing Jun" uniqKey="Ma Q" first="Qing-Jun" last="Ma">Qing-Jun Ma</name>
</author>
</analytic>
<series><title level="j">Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology</title>
<idno type="ISSN">1007-8738</idno>
<imprint><date when="2009" type="published">2009</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cell Line</term>
<term>Humans</term>
<term>Mannose-Binding Protein-Associated Serine Proteases (genetics)</term>
<term>Mannose-Binding Protein-Associated Serine Proteases (metabolism)</term>
<term>Nucleocapsid Proteins (genetics)</term>
<term>Nucleocapsid Proteins (metabolism)</term>
<term>Protein Binding</term>
<term>SARS Virus (genetics)</term>
<term>SARS Virus (metabolism)</term>
<term>Severe Acute Respiratory Syndrome (enzymology)</term>
<term>Severe Acute Respiratory Syndrome (metabolism)</term>
<term>Severe Acute Respiratory Syndrome (virology)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Mannose-Binding Protein-Associated Serine Proteases</term>
<term>Nucleocapsid Proteins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Mannose-Binding Protein-Associated Serine Proteases</term>
<term>Nucleocapsid Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="enzymology" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>SARS Virus</term>
<term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Cell Line</term>
<term>Humans</term>
<term>Protein Binding</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Severe acute respiratory syndrome coronavirus (SARS-CoV) is the etiological agent of SARS, an emerging disease characterized by atypical pneumonia. Using a yeast two-hybrid screen with the nucleocapsid (N)protein of SARS-CoV as a bait, the N protein was found to interact with MAP19, a non-enzymatic protein of MASP(mannan-associated serine protease). The interaction between SARS-CoV N and MAP19 would be further tested in cells in this article.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">19737459</PMID>
<DateCompleted><Year>2010</Year>
<Month>03</Month>
<Day>04</Day>
</DateCompleted>
<DateRevised><Year>2009</Year>
<Month>09</Month>
<Day>09</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">1007-8738</ISSN>
<JournalIssue CitedMedium="Print"><Volume>25</Volume>
<Issue>9</Issue>
<PubDate><Year>2009</Year>
<Month>Sep</Month>
</PubDate>
</JournalIssue>
<Title>Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology</Title>
<ISOAbbreviation>Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi</ISOAbbreviation>
</Journal>
<ArticleTitle>[Study on interaction between SARS-CoV N and MAP19].</ArticleTitle>
<Pagination><MedlinePgn>777-9</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="AIM" NlmCategory="OBJECTIVE">Severe acute respiratory syndrome coronavirus (SARS-CoV) is the etiological agent of SARS, an emerging disease characterized by atypical pneumonia. Using a yeast two-hybrid screen with the nucleocapsid (N)protein of SARS-CoV as a bait, the N protein was found to interact with MAP19, a non-enzymatic protein of MASP(mannan-associated serine protease). The interaction between SARS-CoV N and MAP19 would be further tested in cells in this article.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">The interaction between SARS-CoV N and MAP19 was demonstrated by immuno- coprecipitation, and the amount of MAP19 influenced by SARS-CoV N was investgated by Western blot.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The interaction between SARS-CoV N and MAP19 was already demonstrated by immuno-coprecipitation. SARS-CoV N greatly increased the amount of MAP19.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">SARS-CoV N can bind with MAP19 in cells. Our study may be conductive to further research into the molecular mechanism of action between SARS-CoV N and MAP19.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Liu</LastName>
<ForeName>Jun-li</ForeName>
<Initials>JL</Initials>
<AffiliationInfo><Affiliation>Institute of Biotechnology, Academy of Military Medical Sciences, Beijing 100850, China. liujunli306@sohu.com</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Cao</LastName>
<ForeName>Cheng</ForeName>
<Initials>C</Initials>
</Author>
<Author ValidYN="Y"><LastName>Ma</LastName>
<ForeName>Qing-jun</ForeName>
<Initials>QJ</Initials>
</Author>
</AuthorList>
<Language>chi</Language>
<PublicationTypeList><PublicationType UI="D004740">English Abstract</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>China</Country>
<MedlineTA>Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi</MedlineTA>
<NlmUniqueID>101139110</NlmUniqueID>
<ISSNLinking>1007-8738</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D019590">Nucleocapsid Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C099602">nucleocapsid protein, Coronavirus</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 3.4.21.-</RegistryNumber>
<NameOfSubstance UI="C105296">MASP2 protein, human</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 3.4.21.-</RegistryNumber>
<NameOfSubstance UI="D050606">Mannose-Binding Protein-Associated Serine Proteases</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D002460" MajorTopicYN="N">Cell Line</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D050606" MajorTopicYN="N">Mannose-Binding Protein-Associated Serine Proteases</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D019590" MajorTopicYN="N">Nucleocapsid Proteins</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011485" MajorTopicYN="N">Protein Binding</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D045473" MajorTopicYN="N">SARS Virus</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D045169" MajorTopicYN="N">Severe Acute Respiratory Syndrome</DescriptorName>
<QualifierName UI="Q000201" MajorTopicYN="N">enzymology</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
<QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2009</Year>
<Month>9</Month>
<Day>10</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2009</Year>
<Month>9</Month>
<Day>10</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2010</Year>
<Month>3</Month>
<Day>5</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">19737459</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>

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[Study on interaction between SARS-CoV N and MAP19].

[Study on interaction between SARS-CoV N and MAP19].

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki