The role of host genetic factors in respiratory tract infectious diseases: systematic review, meta-analyses and field synopsis.
Identifieur interne : 000D44 ( PubMed/Corpus ); précédent : 000D43; suivant : 000D45The role of host genetic factors in respiratory tract infectious diseases: systematic review, meta-analyses and field synopsis.
Auteurs : Inga Patar I ; Andrea Gelemanovi ; Mirna Kirin ; Ivana Kol I ; Evropi Theodoratou ; Kenneth J. Baillie ; Menno D. De Jong ; Igor Rudan ; Harry Campbell ; Ozren PolašekSource :
- Scientific reports [ 2045-2322 ] ; 2015.
English descriptors
- KwdEn :
- Chemokine CCL2 (genetics), Databases, Factual, Humans, Interleukin-4 (genetics), Polymorphism, Single Nucleotide, Respiratory Tract Infections (genetics), Respiratory Tract Infections (metabolism), Respiratory Tract Infections (pathology), Toll-Like Receptor 2 (genetics), Tuberculosis (genetics), Tuberculosis (mortality), Tuberculosis (pathology).
- MESH :
- chemical , genetics : Chemokine CCL2, Interleukin-4, Toll-Like Receptor 2.
- genetics : Respiratory Tract Infections, Tuberculosis.
- metabolism : Respiratory Tract Infections.
- mortality : Tuberculosis.
- pathology : Respiratory Tract Infections, Tuberculosis.
- Databases, Factual, Humans, Polymorphism, Single Nucleotide.
Abstract
Host genetic factors have frequently been implicated in respiratory infectious diseases, often with inconsistent results in replication studies. We identified 386 studies from the total of 24,823 studies identified in a systematic search of four bibliographic databases. We performed meta-analyses of studies on tuberculosis, influenza, respiratory syncytial virus, SARS-Coronavirus and pneumonia. One single-nucleotide polymorphism from IL4 gene was significant for pooled respiratory infections (rs2070874; 1.66 [1.29-2.14]). We also detected an association of TLR2 gene with tuberculosis (rs5743708; 3.19 [2.03-5.02]). Subset analyses identified CCL2 as an additional risk factor for tuberculosis (rs1024611; OR = 0.79 [0.72-0.88]). The IL4-TLR2-CCL2 axis could be a highly interesting target for translation towards clinical use. However, this conclusion is based on low credibility of evidence - almost 95% of all identified studies had strong risk of bias or confounding. Future studies must build upon larger-scale collaborations, but also strictly adhere to the highest evidence-based principles in study design, in order to reduce research waste and provide clinically translatable evidence.
DOI: 10.1038/srep16119
PubMed: 26524966
Links to Exploration step
pubmed:26524966Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The role of host genetic factors in respiratory tract infectious diseases: systematic review, meta-analyses and field synopsis.</title><author><name sortKey="Patar I, Inga" sort="Patar I, Inga" uniqKey="Patar I I" first="Inga" last="Patar I">Inga Patar I</name><affiliation><nlm:affiliation>Department of Public Health, University of Split School of Medicine, Split, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Gelemanovi, Andrea" sort="Gelemanovi, Andrea" uniqKey="Gelemanovi A" first="Andrea" last="Gelemanovi">Andrea Gelemanovi</name><affiliation><nlm:affiliation>Department of Public Health, University of Split School of Medicine, Split, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Kirin, Mirna" sort="Kirin, Mirna" uniqKey="Kirin M" first="Mirna" last="Kirin">Mirna Kirin</name><affiliation><nlm:affiliation>Department of Public Health, University of Split School of Medicine, Split, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Kol I, Ivana" sort="Kol I, Ivana" uniqKey="Kol I I" first="Ivana" last="Kol I">Ivana Kol I</name><affiliation><nlm:affiliation>Department of Public Health, University of Split School of Medicine, Split, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Theodoratou, Evropi" sort="Theodoratou, Evropi" uniqKey="Theodoratou E" first="Evropi" last="Theodoratou">Evropi Theodoratou</name><affiliation><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics , University of Edinburgh, Edinburgh, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Baillie, Kenneth J" sort="Baillie, Kenneth J" uniqKey="Baillie K" first="Kenneth J" last="Baillie">Kenneth J. Baillie</name><affiliation><nlm:affiliation>Roslin Institute, University of Edinburgh, Midlothian, UK.</nlm:affiliation></affiliation></author><author><name sortKey="De Jong, Menno D" sort="De Jong, Menno D" uniqKey="De Jong M" first="Menno D" last="De Jong">Menno D. De Jong</name><affiliation><nlm:affiliation>Department of Medical Microbiology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><affiliation><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics , University of Edinburgh, Edinburgh, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><affiliation><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics , University of Edinburgh, Edinburgh, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polašek">Ozren Polašek</name><affiliation><nlm:affiliation>Department of Public Health, University of Split School of Medicine, Split, Croatia.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:26524966</idno><idno type="pmid">26524966</idno><idno type="doi">10.1038/srep16119</idno><idno type="wicri:Area/PubMed/Corpus">000D44</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000D44</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">The role of host genetic factors in respiratory tract infectious diseases: systematic review, meta-analyses and field synopsis.</title><author><name sortKey="Patar I, Inga" sort="Patar I, Inga" uniqKey="Patar I I" first="Inga" last="Patar I">Inga Patar I</name><affiliation><nlm:affiliation>Department of Public Health, University of Split School of Medicine, Split, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Gelemanovi, Andrea" sort="Gelemanovi, Andrea" uniqKey="Gelemanovi A" first="Andrea" last="Gelemanovi">Andrea Gelemanovi</name><affiliation><nlm:affiliation>Department of Public Health, University of Split School of Medicine, Split, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Kirin, Mirna" sort="Kirin, Mirna" uniqKey="Kirin M" first="Mirna" last="Kirin">Mirna Kirin</name><affiliation><nlm:affiliation>Department of Public Health, University of Split School of Medicine, Split, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Kol I, Ivana" sort="Kol I, Ivana" uniqKey="Kol I I" first="Ivana" last="Kol I">Ivana Kol I</name><affiliation><nlm:affiliation>Department of Public Health, University of Split School of Medicine, Split, Croatia.</nlm:affiliation></affiliation></author><author><name sortKey="Theodoratou, Evropi" sort="Theodoratou, Evropi" uniqKey="Theodoratou E" first="Evropi" last="Theodoratou">Evropi Theodoratou</name><affiliation><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics , University of Edinburgh, Edinburgh, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Baillie, Kenneth J" sort="Baillie, Kenneth J" uniqKey="Baillie K" first="Kenneth J" last="Baillie">Kenneth J. Baillie</name><affiliation><nlm:affiliation>Roslin Institute, University of Edinburgh, Midlothian, UK.</nlm:affiliation></affiliation></author><author><name sortKey="De Jong, Menno D" sort="De Jong, Menno D" uniqKey="De Jong M" first="Menno D" last="De Jong">Menno D. De Jong</name><affiliation><nlm:affiliation>Department of Medical Microbiology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.</nlm:affiliation></affiliation></author><author><name sortKey="Rudan, Igor" sort="Rudan, Igor" uniqKey="Rudan I" first="Igor" last="Rudan">Igor Rudan</name><affiliation><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics , University of Edinburgh, Edinburgh, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Campbell, Harry" sort="Campbell, Harry" uniqKey="Campbell H" first="Harry" last="Campbell">Harry Campbell</name><affiliation><nlm:affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics , University of Edinburgh, Edinburgh, UK.</nlm:affiliation></affiliation></author><author><name sortKey="Polasek, Ozren" sort="Polasek, Ozren" uniqKey="Polasek O" first="Ozren" last="Polašek">Ozren Polašek</name><affiliation><nlm:affiliation>Department of Public Health, University of Split School of Medicine, Split, Croatia.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Scientific reports</title><idno type="eISSN">2045-2322</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Chemokine CCL2 (genetics)</term><term>Databases, Factual</term><term>Humans</term><term>Interleukin-4 (genetics)</term><term>Polymorphism, Single Nucleotide</term><term>Respiratory Tract Infections (genetics)</term><term>Respiratory Tract Infections (metabolism)</term><term>Respiratory Tract Infections (pathology)</term><term>Toll-Like Receptor 2 (genetics)</term><term>Tuberculosis (genetics)</term><term>Tuberculosis (mortality)</term><term>Tuberculosis (pathology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Chemokine CCL2</term><term>Interleukin-4</term><term>Toll-Like Receptor 2</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Respiratory Tract Infections</term><term>Tuberculosis</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Respiratory Tract Infections</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Tuberculosis</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Respiratory Tract Infections</term><term>Tuberculosis</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Databases, Factual</term><term>Humans</term><term>Polymorphism, Single Nucleotide</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Host genetic factors have frequently been implicated in respiratory infectious diseases, often with inconsistent results in replication studies. We identified 386 studies from the total of 24,823 studies identified in a systematic search of four bibliographic databases. We performed meta-analyses of studies on tuberculosis, influenza, respiratory syncytial virus, SARS-Coronavirus and pneumonia. One single-nucleotide polymorphism from IL4 gene was significant for pooled respiratory infections (rs2070874; 1.66 [1.29-2.14]). We also detected an association of TLR2 gene with tuberculosis (rs5743708; 3.19 [2.03-5.02]). Subset analyses identified CCL2 as an additional risk factor for tuberculosis (rs1024611; OR = 0.79 [0.72-0.88]). The IL4-TLR2-CCL2 axis could be a highly interesting target for translation towards clinical use. However, this conclusion is based on low credibility of evidence - almost 95% of all identified studies had strong risk of bias or confounding. Future studies must build upon larger-scale collaborations, but also strictly adhere to the highest evidence-based principles in study design, in order to reduce research waste and provide clinically translatable evidence. </div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26524966</PMID><DateCompleted><Year>2016</Year><Month>09</Month><Day>07</Day></DateCompleted><DateRevised><Year>2018</Year><Month>12</Month><Day>02</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">2045-2322</ISSN><JournalIssue CitedMedium="Internet"><Volume>5</Volume><PubDate><Year>2015</Year><Month>Nov</Month><Day>03</Day></PubDate></JournalIssue><Title>Scientific reports</Title><ISOAbbreviation>Sci Rep</ISOAbbreviation></Journal><ArticleTitle>The role of host genetic factors in respiratory tract infectious diseases: systematic review, meta-analyses and field synopsis.</ArticleTitle><Pagination><MedlinePgn>16119</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1038/srep16119</ELocationID><Abstract><AbstractText>Host genetic factors have frequently been implicated in respiratory infectious diseases, often with inconsistent results in replication studies. We identified 386 studies from the total of 24,823 studies identified in a systematic search of four bibliographic databases. We performed meta-analyses of studies on tuberculosis, influenza, respiratory syncytial virus, SARS-Coronavirus and pneumonia. One single-nucleotide polymorphism from IL4 gene was significant for pooled respiratory infections (rs2070874; 1.66 [1.29-2.14]). We also detected an association of TLR2 gene with tuberculosis (rs5743708; 3.19 [2.03-5.02]). Subset analyses identified CCL2 as an additional risk factor for tuberculosis (rs1024611; OR = 0.79 [0.72-0.88]). The IL4-TLR2-CCL2 axis could be a highly interesting target for translation towards clinical use. However, this conclusion is based on low credibility of evidence - almost 95% of all identified studies had strong risk of bias or confounding. Future studies must build upon larger-scale collaborations, but also strictly adhere to the highest evidence-based principles in study design, in order to reduce research waste and provide clinically translatable evidence. </AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Patarčić</LastName><ForeName>Inga</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Department of Public Health, University of Split School of Medicine, Split, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gelemanović</LastName><ForeName>Andrea</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Public Health, University of Split School of Medicine, Split, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kirin</LastName><ForeName>Mirna</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Public Health, University of Split School of Medicine, Split, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kolčić</LastName><ForeName>Ivana</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Department of Public Health, University of Split School of Medicine, Split, Croatia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Theodoratou</LastName><ForeName>Evropi</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics , University of Edinburgh, Edinburgh, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Baillie</LastName><ForeName>Kenneth J</ForeName><Initials>KJ</Initials><AffiliationInfo><Affiliation>Roslin Institute, University of Edinburgh, Midlothian, UK.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Intensive Care Unit, Royal Infirmary of Edinburgh, Edinburgh, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>de Jong</LastName><ForeName>Menno D</ForeName><Initials>MD</Initials><AffiliationInfo><Affiliation>Department of Medical Microbiology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rudan</LastName><ForeName>Igor</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics , University of Edinburgh, Edinburgh, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Campbell</LastName><ForeName>Harry</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics , University of Edinburgh, Edinburgh, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Polašek</LastName><ForeName>Ozren</ForeName><Initials>O</Initials><AffiliationInfo><Affiliation>Department of Public Health, University of Split School of Medicine, Split, Croatia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics , University of Edinburgh, Edinburgh, UK.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>095831</GrantID><Agency>Wellcome Trust</Agency><Country>United Kingdom</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D017418">Meta-Analysis</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D016454">Review</PublicationType><PublicationType UI="D000078182">Systematic Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>11</Month><Day>03</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Sci Rep</MedlineTA><NlmUniqueID>101563288</NlmUniqueID><ISSNLinking>2045-2322</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D018932">Chemokine CCL2</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D051195">Toll-Like Receptor 2</NameOfSubstance></Chemical><Chemical><RegistryNumber>207137-56-2</RegistryNumber><NameOfSubstance UI="D015847">Interleukin-4</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D018932" MajorTopicYN="N">Chemokine CCL2</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016208" MajorTopicYN="N">Databases, Factual</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015847" MajorTopicYN="N">Interleukin-4</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020641" MajorTopicYN="N">Polymorphism, Single Nucleotide</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012141" MajorTopicYN="N">Respiratory Tract Infections</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D051195" MajorTopicYN="N">Toll-Like Receptor 2</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014376" MajorTopicYN="N">Tuberculosis</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000401" MajorTopicYN="N">mortality</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2015</Year><Month>07</Month><Day>20</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2015</Year><Month>10</Month><Day>09</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>11</Month><Day>4</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2015</Year><Month>11</Month><Day>4</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>9</Month><Day>8</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">26524966</ArticleId><ArticleId IdType="pii">srep16119</ArticleId><ArticleId IdType="doi">10.1038/srep16119</ArticleId><ArticleId IdType="pmc">PMC4630784</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Annu Rev Genomics Hum Genet. 2013;14:215-43</Citation><ArticleIdList><ArticleId IdType="pubmed">23724903</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet Oncol. 2012 Jun;13(6):607-15</Citation><ArticleIdList><ArticleId IdType="pubmed">22575588</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Immunol. 2012 Apr;143(1):22-38</Citation><ArticleIdList><ArticleId IdType="pubmed">22377282</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 2009 Aug 1;183(3):1964-74</Citation><ArticleIdList><ArticleId IdType="pubmed">19587014</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet Infect Dis. 2004 Nov;4(11):663-71</Citation><ArticleIdList><ArticleId IdType="pubmed">15522678</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Genet. 2012 Mar;13(3):175-88</Citation><ArticleIdList><ArticleId IdType="pubmed">22310894</ArticleId></ArticleIdList></Reference><Reference><Citation>Ann N Y Acad Sci. 2010 Dec;1214:18-33</Citation><ArticleIdList><ArticleId IdType="pubmed">21091717</ArticleId></ArticleIdList></Reference><Reference><Citation>Bull Hist Med. 2002 Spring;76(1):105-15</Citation><ArticleIdList><ArticleId IdType="pubmed">11875246</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Genet. 2015 May;47(5):523-7</Citation><ArticleIdList><ArticleId IdType="pubmed">25774636</ArticleId></ArticleIdList></Reference><Reference><Citation>Am J Hum Genet. 2007 Aug;81(2):208-27</Citation><ArticleIdList><ArticleId IdType="pubmed">17668372</ArticleId></ArticleIdList></Reference><Reference><Citation>Croat Med J. 2013 Oct 28;54(5):496-500</Citation><ArticleIdList><ArticleId IdType="pubmed">24170729</ArticleId></ArticleIdList></Reference><Reference><Citation>JAMA. 1999 May 26;281(20):1919-26</Citation><ArticleIdList><ArticleId IdType="pubmed">10349896</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 2003 Mar 8;361(9360):865-72</Citation><ArticleIdList><ArticleId IdType="pubmed">12642066</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 1988 Mar 24;318(12):727-32</Citation><ArticleIdList><ArticleId IdType="pubmed">3347221</ArticleId></ArticleIdList></Reference><Reference><Citation>Future Microbiol. 2014;9(8):969-85</Citation><ArticleIdList><ArticleId IdType="pubmed">25302954</ArticleId></ArticleIdList></Reference><Reference><Citation>Cold Spring Harb Perspect Med. 2013 Jan;3(1):a012450</Citation><ArticleIdList><ArticleId IdType="pubmed">23284079</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 1999 Dec 7;96(25):14459-63</Citation><ArticleIdList><ArticleId IdType="pubmed">10588727</ArticleId></ArticleIdList></Reference><Reference><Citation>Atherosclerosis. 2006 Aug;187(2):285-91</Citation><ArticleIdList><ArticleId IdType="pubmed">16249002</ArticleId></ArticleIdList></Reference><Reference><Citation>Infect Immun. 2000 Sep;68(9):5234-40</Citation><ArticleIdList><ArticleId IdType="pubmed">10948149</ArticleId></ArticleIdList></Reference><Reference><Citation>J Epidemiol Community Health. 2012 Sep;66(9):844-54</Citation><ArticleIdList><ArticleId IdType="pubmed">22025194</ArticleId></ArticleIdList></Reference><Reference><Citation>J Infect. 2015 Mar;70(3):255-63</Citation><ArticleIdList><ArticleId IdType="pubmed">25445885</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2011;6(10):e25803</Citation><ArticleIdList><ArticleId IdType="pubmed">21991356</ArticleId></ArticleIdList></Reference><Reference><Citation>Infect Immun. 2011 Mar;79(3):1118-23</Citation><ArticleIdList><ArticleId IdType="pubmed">21173309</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Exp Immunol. 1998 Sep;113(3):317-9</Citation><ArticleIdList><ArticleId IdType="pubmed">9737656</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr HIV/AIDS Rep. 2011 Mar;8(1):38-44</Citation><ArticleIdList><ArticleId IdType="pubmed">21221856</ArticleId></ArticleIdList></Reference><Reference><Citation>J Leukoc Biol. 2009 Nov;86(5):1239-46</Citation><ArticleIdList><ArticleId IdType="pubmed">19641038</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Epidemiol. 2008 Feb;37(1):120-32</Citation><ArticleIdList><ArticleId IdType="pubmed">17898028</ArticleId></ArticleIdList></Reference><Reference><Citation>Bull Hist Med. 1991 Spring;65(1):4-21</Citation><ArticleIdList><ArticleId IdType="pubmed">2021692</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 2014 Jan 11;383(9912):166-75</Citation><ArticleIdList><ArticleId IdType="pubmed">24411645</ArticleId></ArticleIdList></Reference><Reference><Citation>Annu Rev Genet. 2006;40:469-86</Citation><ArticleIdList><ArticleId IdType="pubmed">17094741</ArticleId></ArticleIdList></Reference><Reference><Citation>J Exp Med. 2009 Jun 8;206(6):1395-408</Citation><ArticleIdList><ArticleId IdType="pubmed">19468064</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Genet. 2001 Dec;2(12):967-77</Citation><ArticleIdList><ArticleId IdType="pubmed">11733749</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Immunogenet. 2014 Apr;41(2):98-104</Citation><ArticleIdList><ArticleId IdType="pubmed">23998687</ArticleId></ArticleIdList></Reference><Reference><Citation>Int Immunopharmacol. 2003 May;3(5):627-42</Citation><ArticleIdList><ArticleId IdType="pubmed">12757733</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet Infect Dis. 2006 Oct;6(10):653-63</Citation><ArticleIdList><ArticleId IdType="pubmed">17008174</ArticleId></ArticleIdList></Reference><Reference><Citation>Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13790-4</Citation><ArticleIdList><ArticleId IdType="pubmed">25201988</ArticleId></ArticleIdList></Reference><Reference><Citation>Expert Opin Ther Pat. 2009 Mar;19(3):295-303</Citation><ArticleIdList><ArticleId IdType="pubmed">19441905</ArticleId></ArticleIdList></Reference><Reference><Citation>J Immunol. 1998 Jan 15;160(2):550-4</Citation><ArticleIdList><ArticleId IdType="pubmed">9551886</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2012 Feb 2;366(5):454-61</Citation><ArticleIdList><ArticleId IdType="pubmed">22296079</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Genet. 2014 Jun;15(6):379-93</Citation><ArticleIdList><ArticleId IdType="pubmed">24776769</ArticleId></ArticleIdList></Reference><Reference><Citation>Ther Adv Respir Dis. 2010 Jun;4(3):161-76</Citation><ArticleIdList><ArticleId IdType="pubmed">20530064</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Microbiol. 2009 Dec;7(12):845-55</Citation><ArticleIdList><ArticleId IdType="pubmed">19855401</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Allergy Asthma Rep. 2014 Feb;14(2):411</Citation><ArticleIdList><ArticleId IdType="pubmed">24415464</ArticleId></ArticleIdList></Reference><Reference><Citation>Front Genet. 2014 Aug 25;5:290</Citation><ArticleIdList><ArticleId IdType="pubmed">25202324</ArticleId></ArticleIdList></Reference><Reference><Citation>Transplantation. 2008 Apr 15;85(7):1030-8</Citation><ArticleIdList><ArticleId IdType="pubmed">18408585</ArticleId></ArticleIdList></Reference><Reference><Citation>Trends Genet. 2010 Mar;26(3):119-31</Citation><ArticleIdList><ArticleId IdType="pubmed">20149939</ArticleId></ArticleIdList></Reference><Reference><Citation>EMBO J. 2007 Feb 21;26(4):915-22</Citation><ArticleIdList><ArticleId IdType="pubmed">17255931</ArticleId></ArticleIdList></Reference><Reference><Citation>J Leukoc Biol. 2013 Nov;94(5):885-902</Citation><ArticleIdList><ArticleId IdType="pubmed">23990624</ArticleId></ArticleIdList></Reference><Reference><Citation>Ann Hum Genet. 2000 Nov;64(Pt 6):507-12</Citation><ArticleIdList><ArticleId IdType="pubmed">11281214</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Tuberc Lung Dis. 2012 Feb;16(2):150-6</Citation><ArticleIdList><ArticleId IdType="pubmed">22137597</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet Infect Dis. 2009 Jan;9(1):31-44</Citation><ArticleIdList><ArticleId IdType="pubmed">19036641</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Genet. 2012 Mar;44(3):257-9</Citation><ArticleIdList><ArticleId IdType="pubmed">22306650</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Biol. 2008 Dec 16;6(12):e311</Citation><ArticleIdList><ArticleId IdType="pubmed">19090620</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Biol. 2005 Jun 7;15(11):1022-7</Citation><ArticleIdList><ArticleId IdType="pubmed">15936272</ArticleId></ArticleIdList></Reference><Reference><Citation>Eur Respir J. 2004 Feb;23(2):219-23</Citation><ArticleIdList><ArticleId IdType="pubmed">14979495</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2012;7(2):e25431</Citation><ArticleIdList><ArticleId IdType="pubmed">22347358</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Genet. 2010 Feb;6(2):e1000849</Citation><ArticleIdList><ArticleId IdType="pubmed">20174570</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 2013 Apr 20;381(9875):1405-16</Citation><ArticleIdList><ArticleId IdType="pubmed">23582727</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Med. 2009 Feb 3;6(2):e22</Citation><ArticleIdList><ArticleId IdType="pubmed">19192942</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS Med. 2009 Mar 3;6(3):e28</Citation><ArticleIdList><ArticleId IdType="pubmed">19260758</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Tuberc Lung Dis. 2003 Jun;7(6):599-602</Citation><ArticleIdList><ArticleId IdType="pubmed">12797705</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2003 May 15;423(6937):240</Citation><ArticleIdList><ArticleId IdType="pubmed">12748632</ArticleId></ArticleIdList></Reference><Reference><Citation>Genet Epidemiol. 2009 Feb;33(2):145-50</Citation><ArticleIdList><ArticleId IdType="pubmed">18720477</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Opin Immunol. 2006 Aug;18(4):383-90</Citation><ArticleIdList><ArticleId IdType="pubmed">16765581</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet Infect Dis. 2008 Nov;8(11):710-9</Citation><ArticleIdList><ArticleId IdType="pubmed">18992407</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Immunol. 2014 Dec;14(12):827-35</Citation><ArticleIdList><ArticleId IdType="pubmed">25421702</ArticleId></ArticleIdList></Reference><Reference><Citation>Infect Genet Evol. 2012 Jul;12(5):1120-7</Citation><ArticleIdList><ArticleId IdType="pubmed">22554651</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2013;8(2):e56820</Citation><ArticleIdList><ArticleId IdType="pubmed">23441216</ArticleId></ArticleIdList></Reference><Reference><Citation>Hum Mol Genet. 2014 Feb 1;23(3):796-809</Citation><ArticleIdList><ArticleId IdType="pubmed">24057671</ArticleId></ArticleIdList></Reference><Reference><Citation>Philos Trans R Soc Lond B Biol Sci. 2012 Mar 19;367(1590):850-9</Citation><ArticleIdList><ArticleId IdType="pubmed">22312052</ArticleId></ArticleIdList></Reference><Reference><Citation>Database (Oxford). 2011;2011:bar030</Citation><ArticleIdList><ArticleId IdType="pubmed">21785142</ArticleId></ArticleIdList></Reference><Reference><Citation>Am J Hum Genet. 2000 Aug;67(2):405-16</Citation><ArticleIdList><ArticleId IdType="pubmed">10882571</ArticleId></ArticleIdList></Reference><Reference><Citation>Vet Res. 2014;45:113</Citation><ArticleIdList><ArticleId IdType="pubmed">25479904</ArticleId></ArticleIdList></Reference><Reference><Citation>Retrovirology. 2012;9:70</Citation><ArticleIdList><ArticleId IdType="pubmed">22920050</ArticleId></ArticleIdList></Reference><Reference><Citation>J Infect Dis. 2008 Jan 1;197(1):18-24</Citation><ArticleIdList><ArticleId IdType="pubmed">18171280</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Genet. 2006 Jan;38(1):38-46</Citation><ArticleIdList><ArticleId IdType="pubmed">16369534</ArticleId></ArticleIdList></Reference><Reference><Citation>CMAJ. 2007 Apr 10;176(8):1091-6</Citation><ArticleIdList><ArticleId IdType="pubmed">17420491</ArticleId></ArticleIdList></Reference><Reference><Citation>Philos Trans R Soc Lond B Biol Sci. 2014;369(1645):20130428</Citation><ArticleIdList><ArticleId IdType="pubmed">24821915</ArticleId></ArticleIdList></Reference><Reference><Citation>Front Immunol. 2012 Apr 18;3:79</Citation><ArticleIdList><ArticleId IdType="pubmed">22566960</ArticleId></ArticleIdList></Reference><Reference><Citation>Lancet. 2010 May 1;375(9725):1545-55</Citation><ArticleIdList><ArticleId IdType="pubmed">20399493</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 1997 Dec 11;337(24):1720-5</Citation><ArticleIdList><ArticleId IdType="pubmed">9392697</ArticleId></ArticleIdList></Reference><Reference><Citation>Immunol Cell Biol. 2014 Oct;92(9):741-6</Citation><ArticleIdList><ArticleId IdType="pubmed">24983458</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Invest. 2009 Sep;119(9):2506-14</Citation><ArticleIdList><ArticleId IdType="pubmed">19729848</ArticleId></ArticleIdList></Reference><Reference><Citation>J Interferon Cytokine Res. 2009 Jun;29(6):313-26</Citation><ArticleIdList><ArticleId IdType="pubmed">19441883</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Genet. 2010 Sep;42(9):739-41</Citation><ArticleIdList><ArticleId IdType="pubmed">20694014</ArticleId></ArticleIdList></Reference><Reference><Citation>Tissue Antigens. 2011 Nov;78(5):333-44</Citation><ArticleIdList><ArticleId IdType="pubmed">21988720</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Immunol. 2007 Nov;8(11):1165-71</Citation><ArticleIdList><ArticleId IdType="pubmed">17952041</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000D44 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000D44 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:26524966
|texte= The role of host genetic factors in respiratory tract infectious diseases: systematic review, meta-analyses and field synopsis.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:26524966" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a SrasV1
| This area was generated with Dilib version V0.6.33. |  |