The novel zoonotic COVID-19 pandemic: An expected global health concern.
Identifieur interne : 000417 ( PubMed/Corpus ); précédent : 000416; suivant : 000418The novel zoonotic COVID-19 pandemic: An expected global health concern.
Auteurs : Carlo Contini ; Mariachiara Di Nuzzo ; Nicole Barp ; Aurora Bonazza ; Roberto De Giorgio ; Mauro Tognon ; Salvatore RubinoSource :
- Journal of infection in developing countries [ 1972-2680 ] ; 2020.
English descriptors
- KwdEn :
- Animals, Betacoronavirus, Biological Evolution, Camelus, China (epidemiology), Chiroptera, Civil Defense, Communicable Diseases, Emerging, Coronavirus (genetics), Coronavirus Infections (drug therapy), Coronavirus Infections (epidemiology), Coronavirus Infections (prevention & control), Coronavirus Infections (therapy), Coronavirus Infections (transmission), Disease Outbreaks, Disease Reservoirs, Epidemiological Monitoring, Global Health, Human Activities, Italy, Middle East Respiratory Syndrome Coronavirus, Pandemics (prevention & control), Pneumonia, Viral (epidemiology), Pneumonia, Viral (prevention & control), Pneumonia, Viral (therapy), Pneumonia, Viral (transmission), SARS Virus, Severe Acute Respiratory Syndrome (epidemiology), Viral Vaccines, Zoonoses (epidemiology).
- MESH :
- chemical : Viral Vaccines.
- geographic , epidemiology : China.
- drug therapy : Coronavirus Infections.
- epidemiology : Coronavirus Infections, Pneumonia, Viral, Severe Acute Respiratory Syndrome, Zoonoses.
- genetics : Coronavirus.
- prevention & control : Coronavirus Infections, Pandemics, Pneumonia, Viral.
- therapy : Coronavirus Infections, Pneumonia, Viral.
- transmission : Coronavirus Infections, Pneumonia, Viral.
- Animals, Betacoronavirus, Biological Evolution, Camelus, Chiroptera, Civil Defense, Communicable Diseases, Emerging, Disease Outbreaks, Disease Reservoirs, Epidemiological Monitoring, Global Health, Human Activities, Italy, Middle East Respiratory Syndrome Coronavirus, SARS Virus.
Abstract
18 years ago, in 2002, the world was astonished by the appearance of Severe Acute Respiratory Syndrome (SARS), supported by a zoonotic coronavirus, called SARS-CoV, from the Guangdong Province of southern China. After about 10 years, in 2012, another similar coronavirus triggered the Middle East Respiratory Syndrome (MERS-CoV) in Saudi Arabia. Both caused severe pneumonia killing 774 and 858 people with 8700 cases of confirmed infection for the former, and 2494 for the latter, causing significant economic losses. 8 years later, despite the MERS outbreak remaining in certain parts of the world, at the end of 2019, a new zoonotic coronavirus (SARS-CoV-2) and responsible of coronavirus Disease (COVID-19), arose from Wuhan, Hubei Province, China. It spread rapidly and to date has killed 3,242 persons with more than 81,000 cases of infection in China and causing over 126,000 global cases and 5,414 deaths in 166 other countries around the world, especially Italy. SARS-CoV-2 would seem to have come from a bat, but the intermediate reservoir continues to be unknown. Nonetheless, as for SARS-CoV and MERS CoV, the Spillover effect linked to animal-human promiscuity, human activities including deforestation, illegal bush-trafficking and bushmeat, cannot be excluded. Recently, however, evidence of inter-human only transmission of SARS-CoV-2 has been accumulated and thus, the outbreak seems to be spreading by human-to-human transmission throughout a large part of the world. Herein we will provide with an update on the main features of COVID-19 and suggest possible solutions how to halt the expansion of this novel pandemic.
DOI: 10.3855/jidc.12671
PubMed: 32235085
Links to Exploration step
pubmed:32235085Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The novel zoonotic COVID-19 pandemic: An expected global health concern.</title><author><name sortKey="Contini, Carlo" sort="Contini, Carlo" uniqKey="Contini C" first="Carlo" last="Contini">Carlo Contini</name><affiliation><nlm:affiliation>Infectious Diseases and Dermatology Section, Department of Medical Sciences, University of Ferrara, Ferrara, Italy. cnc@unife.it.</nlm:affiliation></affiliation></author><author><name sortKey="Di Nuzzo, Mariachiara" sort="Di Nuzzo, Mariachiara" uniqKey="Di Nuzzo M" first="Mariachiara" last="Di Nuzzo">Mariachiara Di Nuzzo</name><affiliation><nlm:affiliation>Infectious Diseases and Dermatology Section, Department of Medical Sciences, University of Ferrara, Ferrara, Italy. mariachiara.dinuzzo@student.unife.it.</nlm:affiliation></affiliation></author><author><name sortKey="Barp, Nicole" sort="Barp, Nicole" uniqKey="Barp N" first="Nicole" last="Barp">Nicole Barp</name><affiliation><nlm:affiliation>Infectious Diseases and Dermatology Section, Department of Medical Sciences, University of Ferrara, Ferrara, Italy. nicole.barp@student.unife.it.</nlm:affiliation></affiliation></author><author><name sortKey="Bonazza, Aurora" sort="Bonazza, Aurora" uniqKey="Bonazza A" first="Aurora" last="Bonazza">Aurora Bonazza</name><affiliation><nlm:affiliation>Infectious Diseases and Dermatology Section, Department of Medical Sciences, University of Ferrara, Ferrara, Italy. aurora.bonazza@student.unife.it.</nlm:affiliation></affiliation></author><author><name sortKey="De Giorgio, Roberto" sort="De Giorgio, Roberto" uniqKey="De Giorgio R" first="Roberto" last="De Giorgio">Roberto De Giorgio</name><affiliation><nlm:affiliation>Internal Medicine Unit, Department of Morphology, Surgery and Experimental Medicine; University of Ferrara, Ferrara, Italy. dgrrrt@unife.it.</nlm:affiliation></affiliation></author><author><name sortKey="Tognon, Mauro" sort="Tognon, Mauro" uniqKey="Tognon M" first="Mauro" last="Tognon">Mauro Tognon</name><affiliation><nlm:affiliation>Pathology, Oncology and Experimental Biology Section, Department of Medical Sciences, University of Ferrara, Ferrara, Italy. tgm@unife.it.</nlm:affiliation></affiliation></author><author><name sortKey="Rubino, Salvatore" sort="Rubino, Salvatore" uniqKey="Rubino S" first="Salvatore" last="Rubino">Salvatore Rubino</name><affiliation><nlm:affiliation>Department of Biomedical Sciences, Microbiology, University of Sassari, Sassari, Italy. srubino@jidc.org.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32235085</idno><idno type="pmid">32235085</idno><idno type="doi">10.3855/jidc.12671</idno><idno type="wicri:Area/PubMed/Corpus">000417</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000417</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">The novel zoonotic COVID-19 pandemic: An expected global health concern.</title><author><name sortKey="Contini, Carlo" sort="Contini, Carlo" uniqKey="Contini C" first="Carlo" last="Contini">Carlo Contini</name><affiliation><nlm:affiliation>Infectious Diseases and Dermatology Section, Department of Medical Sciences, University of Ferrara, Ferrara, Italy. cnc@unife.it.</nlm:affiliation></affiliation></author><author><name sortKey="Di Nuzzo, Mariachiara" sort="Di Nuzzo, Mariachiara" uniqKey="Di Nuzzo M" first="Mariachiara" last="Di Nuzzo">Mariachiara Di Nuzzo</name><affiliation><nlm:affiliation>Infectious Diseases and Dermatology Section, Department of Medical Sciences, University of Ferrara, Ferrara, Italy. mariachiara.dinuzzo@student.unife.it.</nlm:affiliation></affiliation></author><author><name sortKey="Barp, Nicole" sort="Barp, Nicole" uniqKey="Barp N" first="Nicole" last="Barp">Nicole Barp</name><affiliation><nlm:affiliation>Infectious Diseases and Dermatology Section, Department of Medical Sciences, University of Ferrara, Ferrara, Italy. nicole.barp@student.unife.it.</nlm:affiliation></affiliation></author><author><name sortKey="Bonazza, Aurora" sort="Bonazza, Aurora" uniqKey="Bonazza A" first="Aurora" last="Bonazza">Aurora Bonazza</name><affiliation><nlm:affiliation>Infectious Diseases and Dermatology Section, Department of Medical Sciences, University of Ferrara, Ferrara, Italy. aurora.bonazza@student.unife.it.</nlm:affiliation></affiliation></author><author><name sortKey="De Giorgio, Roberto" sort="De Giorgio, Roberto" uniqKey="De Giorgio R" first="Roberto" last="De Giorgio">Roberto De Giorgio</name><affiliation><nlm:affiliation>Internal Medicine Unit, Department of Morphology, Surgery and Experimental Medicine; University of Ferrara, Ferrara, Italy. dgrrrt@unife.it.</nlm:affiliation></affiliation></author><author><name sortKey="Tognon, Mauro" sort="Tognon, Mauro" uniqKey="Tognon M" first="Mauro" last="Tognon">Mauro Tognon</name><affiliation><nlm:affiliation>Pathology, Oncology and Experimental Biology Section, Department of Medical Sciences, University of Ferrara, Ferrara, Italy. tgm@unife.it.</nlm:affiliation></affiliation></author><author><name sortKey="Rubino, Salvatore" sort="Rubino, Salvatore" uniqKey="Rubino S" first="Salvatore" last="Rubino">Salvatore Rubino</name><affiliation><nlm:affiliation>Department of Biomedical Sciences, Microbiology, University of Sassari, Sassari, Italy. srubino@jidc.org.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Journal of infection in developing countries</title><idno type="eISSN">1972-2680</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Betacoronavirus</term><term>Biological Evolution</term><term>Camelus</term><term>China (epidemiology)</term><term>Chiroptera</term><term>Civil Defense</term><term>Communicable Diseases, Emerging</term><term>Coronavirus (genetics)</term><term>Coronavirus Infections (drug therapy)</term><term>Coronavirus Infections (epidemiology)</term><term>Coronavirus Infections (prevention & control)</term><term>Coronavirus Infections (therapy)</term><term>Coronavirus Infections (transmission)</term><term>Disease Outbreaks</term><term>Disease Reservoirs</term><term>Epidemiological Monitoring</term><term>Global Health</term><term>Human Activities</term><term>Italy</term><term>Middle East Respiratory Syndrome Coronavirus</term><term>Pandemics (prevention & control)</term><term>Pneumonia, Viral (epidemiology)</term><term>Pneumonia, Viral (prevention & control)</term><term>Pneumonia, Viral (therapy)</term><term>Pneumonia, Viral (transmission)</term><term>SARS Virus</term><term>Severe Acute Respiratory Syndrome (epidemiology)</term><term>Viral Vaccines</term><term>Zoonoses (epidemiology)</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Viral Vaccines</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>China</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term><term>Severe Acute Respiratory Syndrome</term><term>Zoonoses</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Coronavirus Infections</term><term>Pandemics</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Betacoronavirus</term><term>Biological Evolution</term><term>Camelus</term><term>Chiroptera</term><term>Civil Defense</term><term>Communicable Diseases, Emerging</term><term>Disease Outbreaks</term><term>Disease Reservoirs</term><term>Epidemiological Monitoring</term><term>Global Health</term><term>Human Activities</term><term>Italy</term><term>Middle East Respiratory Syndrome Coronavirus</term><term>SARS Virus</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">18 years ago, in 2002, the world was astonished by the appearance of Severe Acute Respiratory Syndrome (SARS), supported by a zoonotic coronavirus, called SARS-CoV, from the Guangdong Province of southern China. After about 10 years, in 2012, another similar coronavirus triggered the Middle East Respiratory Syndrome (MERS-CoV) in Saudi Arabia. Both caused severe pneumonia killing 774 and 858 people with 8700 cases of confirmed infection for the former, and 2494 for the latter, causing significant economic losses. 8 years later, despite the MERS outbreak remaining in certain parts of the world, at the end of 2019, a new zoonotic coronavirus (SARS-CoV-2) and responsible of coronavirus Disease (COVID-19), arose from Wuhan, Hubei Province, China. It spread rapidly and to date has killed 3,242 persons with more than 81,000 cases of infection in China and causing over 126,000 global cases and 5,414 deaths in 166 other countries around the world, especially Italy. SARS-CoV-2 would seem to have come from a bat, but the intermediate reservoir continues to be unknown. Nonetheless, as for SARS-CoV and MERS CoV, the Spillover effect linked to animal-human promiscuity, human activities including deforestation, illegal bush-trafficking and bushmeat, cannot be excluded. Recently, however, evidence of inter-human only transmission of SARS-CoV-2 has been accumulated and thus, the outbreak seems to be spreading by human-to-human transmission throughout a large part of the world. Herein we will provide with an update on the main features of COVID-19 and suggest possible solutions how to halt the expansion of this novel pandemic.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32235085</PMID><DateCompleted><Year>2020</Year><Month>04</Month><Day>09</Day></DateCompleted><DateRevised><Year>2020</Year><Month>04</Month><Day>09</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1972-2680</ISSN><JournalIssue CitedMedium="Internet"><Volume>14</Volume><Issue>3</Issue><PubDate><Year>2020</Year><Month>03</Month><Day>31</Day></PubDate></JournalIssue><Title>Journal of infection in developing countries</Title><ISOAbbreviation>J Infect Dev Ctries</ISOAbbreviation></Journal><ArticleTitle>The novel zoonotic COVID-19 pandemic: An expected global health concern.</ArticleTitle><Pagination><MedlinePgn>254-264</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.3855/jidc.12671</ELocationID><Abstract><AbstractText>18 years ago, in 2002, the world was astonished by the appearance of Severe Acute Respiratory Syndrome (SARS), supported by a zoonotic coronavirus, called SARS-CoV, from the Guangdong Province of southern China. After about 10 years, in 2012, another similar coronavirus triggered the Middle East Respiratory Syndrome (MERS-CoV) in Saudi Arabia. Both caused severe pneumonia killing 774 and 858 people with 8700 cases of confirmed infection for the former, and 2494 for the latter, causing significant economic losses. 8 years later, despite the MERS outbreak remaining in certain parts of the world, at the end of 2019, a new zoonotic coronavirus (SARS-CoV-2) and responsible of coronavirus Disease (COVID-19), arose from Wuhan, Hubei Province, China. It spread rapidly and to date has killed 3,242 persons with more than 81,000 cases of infection in China and causing over 126,000 global cases and 5,414 deaths in 166 other countries around the world, especially Italy. SARS-CoV-2 would seem to have come from a bat, but the intermediate reservoir continues to be unknown. Nonetheless, as for SARS-CoV and MERS CoV, the Spillover effect linked to animal-human promiscuity, human activities including deforestation, illegal bush-trafficking and bushmeat, cannot be excluded. Recently, however, evidence of inter-human only transmission of SARS-CoV-2 has been accumulated and thus, the outbreak seems to be spreading by human-to-human transmission throughout a large part of the world. Herein we will provide with an update on the main features of COVID-19 and suggest possible solutions how to halt the expansion of this novel pandemic.</AbstractText><CopyrightInformation>Copyright (c) 2020 Carlo Contini, Mariachiara Di Nuzzo, Nicole Barp, Aurora Bonazza, Roberto De Giorgio, Mauro Tognon, Salvatore Rubino.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Contini</LastName><ForeName>Carlo</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Infectious Diseases and Dermatology Section, Department of Medical Sciences, University of Ferrara, Ferrara, Italy. cnc@unife.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Di Nuzzo</LastName><ForeName>Mariachiara</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Infectious Diseases and Dermatology Section, Department of Medical Sciences, University of Ferrara, Ferrara, Italy. mariachiara.dinuzzo@student.unife.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Barp</LastName><ForeName>Nicole</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Infectious Diseases and Dermatology Section, Department of Medical Sciences, University of Ferrara, Ferrara, Italy. nicole.barp@student.unife.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bonazza</LastName><ForeName>Aurora</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Infectious Diseases and Dermatology Section, Department of Medical Sciences, University of Ferrara, Ferrara, Italy. aurora.bonazza@student.unife.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>De Giorgio</LastName><ForeName>Roberto</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Internal Medicine Unit, Department of Morphology, Surgery and Experimental Medicine; University of Ferrara, Ferrara, Italy. dgrrrt@unife.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tognon</LastName><ForeName>Mauro</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Pathology, Oncology and Experimental Biology Section, Department of Medical Sciences, University of Ferrara, Ferrara, Italy. tgm@unife.it.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Rubino</LastName><ForeName>Salvatore</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Biomedical Sciences, Microbiology, University of Sassari, Sassari, Italy. srubino@jidc.org.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>03</Month><Day>31</Day></ArticleDate></Article><MedlineJournalInfo><Country>Italy</Country><MedlineTA>J Infect Dev Ctries</MedlineTA><NlmUniqueID>101305410</NlmUniqueID><ISSNLinking>1972-2680</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C000669933">COVID-19 vaccine</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014765">Viral Vaccines</NameOfSubstance></Chemical></ChemicalList><SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName><SupplMeshName Type="Protocol" UI="C000705127">COVID-19 drug treatment</SupplMeshName><SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName></SupplMeshList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="N">Betacoronavirus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005075" MajorTopicYN="N">Biological Evolution</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002162" MajorTopicYN="N">Camelus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002681" MajorTopicYN="N" Type="Geographic">China</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002685" MajorTopicYN="N">Chiroptera</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002959" MajorTopicYN="N">Civil Defense</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D021821" MajorTopicYN="N">Communicable Diseases, Emerging</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017934" MajorTopicYN="Y">Coronavirus</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="Y">Coronavirus Infections</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName><QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName><QualifierName UI="Q000635" MajorTopicYN="N">transmission</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004196" MajorTopicYN="Y">Disease Outbreaks</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004197" MajorTopicYN="N">Disease Reservoirs</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D062665" MajorTopicYN="Y">Epidemiological Monitoring</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014943" MajorTopicYN="Y">Global Health</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006802" MajorTopicYN="N">Human Activities</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007558" MajorTopicYN="N" Type="Geographic">Italy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D065207" MajorTopicYN="N">Middle East Respiratory Syndrome Coronavirus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058873" MajorTopicYN="Y">Pandemics</DescriptorName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011024" MajorTopicYN="Y">Pneumonia, Viral</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName><QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName><QualifierName UI="Q000635" MajorTopicYN="N">transmission</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D045473" MajorTopicYN="N">SARS Virus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D045169" MajorTopicYN="N">Severe Acute Respiratory Syndrome</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014765" MajorTopicYN="N">Viral Vaccines</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015047" MajorTopicYN="Y">Zoonoses</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">COVID-19</Keyword><Keyword MajorTopicYN="Y">MERS CoV</Keyword><Keyword MajorTopicYN="Y">SARS CoV</Keyword><Keyword MajorTopicYN="Y">SARS-CoV-2</Keyword><Keyword MajorTopicYN="Y">drugs</Keyword><Keyword MajorTopicYN="Y">spillover</Keyword></KeywordList><CoiStatement>No Conflict of Interest is declared</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>03</Month><Day>15</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>03</Month><Day>17</Day></PubMedPubDate><PubMedPubDate 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