Clinical Course and Outcomes of Patients with Severe Acute Respiratory Syndrome Coronavirus 2 Infection: a Preliminary Report of the First 28 Patients from the Korean Cohort Study on COVID-19.
Identifieur interne : 000379 ( PubMed/Corpus ); précédent : 000378; suivant : 000380Clinical Course and Outcomes of Patients with Severe Acute Respiratory Syndrome Coronavirus 2 Infection: a Preliminary Report of the First 28 Patients from the Korean Cohort Study on COVID-19.
Auteurs : Eu Suk Kim ; Bum Sik Chin ; Chang Kyung Kang ; Nam Joong Kim ; Yu Min Kang ; Jae Phil Choi ; Dong Hyun Oh ; Jeong Han Kim ; Boram Koh ; Seong Eun Kim ; Na Ra Yun ; Jae Hoon Lee ; Jin Yong Kim ; Yeonjae Kim ; Ji Hwan Bang ; Kyoung Ho Song ; Hong Bin Kim ; Ki Hyun Chung ; Myoung Don OhSource :
- Journal of Korean medical science [ 1598-6357 ] ; 2020.
English descriptors
- KwdEn :
- Adult, Aged, Asymptomatic Diseases, Betacoronavirus, C-Reactive Protein (analysis), Cohort Studies, Coronavirus Infections (complications), Coronavirus Infections (diagnostic imaging), Cough (etiology), Diarrhea (etiology), Fever (etiology), Humans, Lymphopenia (etiology), Male, Middle Aged, Oxygen Inhalation Therapy, Pandemics, Pharyngitis (etiology), Pneumonia, Viral (complications), Pneumonia, Viral (diagnostic imaging), Prodromal Symptoms, Radiography, Thoracic, Real-Time Polymerase Chain Reaction, Republic of Korea, Retrospective Studies, Time Factors, Tomography, X-Ray Computed, Young Adult.
- MESH :
- chemical , analysis : C-Reactive Protein.
- geographic : Republic of Korea.
- complications : Coronavirus Infections, Pneumonia, Viral.
- diagnostic imaging : Coronavirus Infections, Pneumonia, Viral.
- etiology : Cough, Diarrhea, Fever, Lymphopenia, Pharyngitis.
- Adult, Aged, Asymptomatic Diseases, Betacoronavirus, Cohort Studies, Humans, Male, Middle Aged, Oxygen Inhalation Therapy, Pandemics, Prodromal Symptoms, Radiography, Thoracic, Real-Time Polymerase Chain Reaction, Retrospective Studies, Time Factors, Tomography, X-Ray Computed, Young Adult.
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected pneumonia emerged in Wuhan, China in December 2019. In this retrospective multicenter study, we investigated the clinical course and outcomes of novel coronavirus disease 2019 (COVID-19) from early cases in Republic of Korea.
DOI: 10.3346/jkms.2020.35.e142
PubMed: 32242348
Links to Exploration step
pubmed:32242348Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Clinical Course and Outcomes of Patients with Severe Acute Respiratory Syndrome Coronavirus 2 Infection: a Preliminary Report of the First 28 Patients from the Korean Cohort Study on COVID-19.</title><author><name sortKey="Kim, Eu Suk" sort="Kim, Eu Suk" uniqKey="Kim E" first="Eu Suk" last="Kim">Eu Suk Kim</name><affiliation><nlm:affiliation>Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Chin, Bum Sik" sort="Chin, Bum Sik" uniqKey="Chin B" first="Bum Sik" last="Chin">Bum Sik Chin</name><affiliation><nlm:affiliation>Division of Infectious Diseases, Department of Internal Medicine, National Medical Center, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kang, Chang Kyung" sort="Kang, Chang Kyung" uniqKey="Kang C" first="Chang Kyung" last="Kang">Chang Kyung Kang</name><affiliation><nlm:affiliation>Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Nam Joong" sort="Kim, Nam Joong" uniqKey="Kim N" first="Nam Joong" last="Kim">Nam Joong Kim</name><affiliation><nlm:affiliation>Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kang, Yu Min" sort="Kang, Yu Min" uniqKey="Kang Y" first="Yu Min" last="Kang">Yu Min Kang</name><affiliation><nlm:affiliation>Department of Infectious Diseases, Myongji Hospital, Goyang, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Choi, Jae Phil" sort="Choi, Jae Phil" uniqKey="Choi J" first="Jae Phil" last="Choi">Jae Phil Choi</name><affiliation><nlm:affiliation>Department of Internal Medicine, Seoul Medical Center, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Oh, Dong Hyun" sort="Oh, Dong Hyun" uniqKey="Oh D" first="Dong Hyun" last="Oh">Dong Hyun Oh</name><affiliation><nlm:affiliation>Department of Internal Medicine, Seoul Medical Center, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Jeong Han" sort="Kim, Jeong Han" uniqKey="Kim J" first="Jeong Han" last="Kim">Jeong Han Kim</name><affiliation><nlm:affiliation>Division of Infectious Diseases, Department of Internal Medicine, Armed Forces Capital Hospital, Seongnam, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Koh, Boram" sort="Koh, Boram" uniqKey="Koh B" first="Boram" last="Koh">Boram Koh</name><affiliation><nlm:affiliation>Department of Internal Medicine, Gyeonggi Provincial Medical Center Ansung Hospital, Anseong, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Seong Eun" sort="Kim, Seong Eun" uniqKey="Kim S" first="Seong Eun" last="Kim">Seong Eun Kim</name><affiliation><nlm:affiliation>Department of Infectious Diseases, Chonnam National University Medical School, Gwangju, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Yun, Na Ra" sort="Yun, Na Ra" uniqKey="Yun N" first="Na Ra" last="Yun">Na Ra Yun</name><affiliation><nlm:affiliation>Department of Internal Medicine, College of Medicine, Chosun University, Gwangju, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Lee, Jae Hoon" sort="Lee, Jae Hoon" uniqKey="Lee J" first="Jae Hoon" last="Lee">Jae Hoon Lee</name><affiliation><nlm:affiliation>Department of Internal Medicine, Wonkwang University School of Medicine, Iksan, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Jin Yong" sort="Kim, Jin Yong" uniqKey="Kim J" first="Jin Yong" last="Kim">Jin Yong Kim</name><affiliation><nlm:affiliation>Division of Infectious Diseases, Department of Internal Medicine, Incheon Medical Center, Incheon, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Yeonjae" sort="Kim, Yeonjae" uniqKey="Kim Y" first="Yeonjae" last="Kim">Yeonjae Kim</name><affiliation><nlm:affiliation>Division of Infectious Diseases, Department of Internal Medicine, National Medical Center, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Bang, Ji Hwan" sort="Bang, Ji Hwan" uniqKey="Bang J" first="Ji Hwan" last="Bang">Ji Hwan Bang</name><affiliation><nlm:affiliation>Division of Infectious Diseases, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Song, Kyoung Ho" sort="Song, Kyoung Ho" uniqKey="Song K" first="Kyoung Ho" last="Song">Kyoung Ho Song</name><affiliation><nlm:affiliation>Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Hong Bin" sort="Kim, Hong Bin" uniqKey="Kim H" first="Hong Bin" last="Kim">Hong Bin Kim</name><affiliation><nlm:affiliation>Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Chung, Ki Hyun" sort="Chung, Ki Hyun" uniqKey="Chung K" first="Ki Hyun" last="Chung">Ki Hyun Chung</name><affiliation><nlm:affiliation>Department of Pediatrics, National Medical Center, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Oh, Myoung Don" sort="Oh, Myoung Don" uniqKey="Oh M" first="Myoung Don" last="Oh">Myoung Don Oh</name><affiliation><nlm:affiliation>Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. mdohmd@snu.ac.kr.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32242348</idno><idno type="pmid">32242348</idno><idno type="doi">10.3346/jkms.2020.35.e142</idno><idno type="wicri:Area/PubMed/Corpus">000379</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000379</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Clinical Course and Outcomes of Patients with Severe Acute Respiratory Syndrome Coronavirus 2 Infection: a Preliminary Report of the First 28 Patients from the Korean Cohort Study on COVID-19.</title><author><name sortKey="Kim, Eu Suk" sort="Kim, Eu Suk" uniqKey="Kim E" first="Eu Suk" last="Kim">Eu Suk Kim</name><affiliation><nlm:affiliation>Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Chin, Bum Sik" sort="Chin, Bum Sik" uniqKey="Chin B" first="Bum Sik" last="Chin">Bum Sik Chin</name><affiliation><nlm:affiliation>Division of Infectious Diseases, Department of Internal Medicine, National Medical Center, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kang, Chang Kyung" sort="Kang, Chang Kyung" uniqKey="Kang C" first="Chang Kyung" last="Kang">Chang Kyung Kang</name><affiliation><nlm:affiliation>Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Nam Joong" sort="Kim, Nam Joong" uniqKey="Kim N" first="Nam Joong" last="Kim">Nam Joong Kim</name><affiliation><nlm:affiliation>Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kang, Yu Min" sort="Kang, Yu Min" uniqKey="Kang Y" first="Yu Min" last="Kang">Yu Min Kang</name><affiliation><nlm:affiliation>Department of Infectious Diseases, Myongji Hospital, Goyang, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Choi, Jae Phil" sort="Choi, Jae Phil" uniqKey="Choi J" first="Jae Phil" last="Choi">Jae Phil Choi</name><affiliation><nlm:affiliation>Department of Internal Medicine, Seoul Medical Center, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Oh, Dong Hyun" sort="Oh, Dong Hyun" uniqKey="Oh D" first="Dong Hyun" last="Oh">Dong Hyun Oh</name><affiliation><nlm:affiliation>Department of Internal Medicine, Seoul Medical Center, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Jeong Han" sort="Kim, Jeong Han" uniqKey="Kim J" first="Jeong Han" last="Kim">Jeong Han Kim</name><affiliation><nlm:affiliation>Division of Infectious Diseases, Department of Internal Medicine, Armed Forces Capital Hospital, Seongnam, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Koh, Boram" sort="Koh, Boram" uniqKey="Koh B" first="Boram" last="Koh">Boram Koh</name><affiliation><nlm:affiliation>Department of Internal Medicine, Gyeonggi Provincial Medical Center Ansung Hospital, Anseong, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Seong Eun" sort="Kim, Seong Eun" uniqKey="Kim S" first="Seong Eun" last="Kim">Seong Eun Kim</name><affiliation><nlm:affiliation>Department of Infectious Diseases, Chonnam National University Medical School, Gwangju, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Yun, Na Ra" sort="Yun, Na Ra" uniqKey="Yun N" first="Na Ra" last="Yun">Na Ra Yun</name><affiliation><nlm:affiliation>Department of Internal Medicine, College of Medicine, Chosun University, Gwangju, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Lee, Jae Hoon" sort="Lee, Jae Hoon" uniqKey="Lee J" first="Jae Hoon" last="Lee">Jae Hoon Lee</name><affiliation><nlm:affiliation>Department of Internal Medicine, Wonkwang University School of Medicine, Iksan, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Jin Yong" sort="Kim, Jin Yong" uniqKey="Kim J" first="Jin Yong" last="Kim">Jin Yong Kim</name><affiliation><nlm:affiliation>Division of Infectious Diseases, Department of Internal Medicine, Incheon Medical Center, Incheon, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Yeonjae" sort="Kim, Yeonjae" uniqKey="Kim Y" first="Yeonjae" last="Kim">Yeonjae Kim</name><affiliation><nlm:affiliation>Division of Infectious Diseases, Department of Internal Medicine, National Medical Center, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Bang, Ji Hwan" sort="Bang, Ji Hwan" uniqKey="Bang J" first="Ji Hwan" last="Bang">Ji Hwan Bang</name><affiliation><nlm:affiliation>Division of Infectious Diseases, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Song, Kyoung Ho" sort="Song, Kyoung Ho" uniqKey="Song K" first="Kyoung Ho" last="Song">Kyoung Ho Song</name><affiliation><nlm:affiliation>Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Hong Bin" sort="Kim, Hong Bin" uniqKey="Kim H" first="Hong Bin" last="Kim">Hong Bin Kim</name><affiliation><nlm:affiliation>Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Chung, Ki Hyun" sort="Chung, Ki Hyun" uniqKey="Chung K" first="Ki Hyun" last="Chung">Ki Hyun Chung</name><affiliation><nlm:affiliation>Department of Pediatrics, National Medical Center, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Oh, Myoung Don" sort="Oh, Myoung Don" uniqKey="Oh M" first="Myoung Don" last="Oh">Myoung Don Oh</name><affiliation><nlm:affiliation>Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. mdohmd@snu.ac.kr.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Journal of Korean medical science</title><idno type="eISSN">1598-6357</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Asymptomatic Diseases</term><term>Betacoronavirus</term><term>C-Reactive Protein (analysis)</term><term>Cohort Studies</term><term>Coronavirus Infections (complications)</term><term>Coronavirus Infections (diagnostic imaging)</term><term>Cough (etiology)</term><term>Diarrhea (etiology)</term><term>Fever (etiology)</term><term>Humans</term><term>Lymphopenia (etiology)</term><term>Male</term><term>Middle Aged</term><term>Oxygen Inhalation Therapy</term><term>Pandemics</term><term>Pharyngitis (etiology)</term><term>Pneumonia, Viral (complications)</term><term>Pneumonia, Viral (diagnostic imaging)</term><term>Prodromal Symptoms</term><term>Radiography, Thoracic</term><term>Real-Time Polymerase Chain Reaction</term><term>Republic of Korea</term><term>Retrospective Studies</term><term>Time Factors</term><term>Tomography, X-Ray Computed</term><term>Young Adult</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>C-Reactive Protein</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Republic of Korea</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Cough</term><term>Diarrhea</term><term>Fever</term><term>Lymphopenia</term><term>Pharyngitis</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Asymptomatic Diseases</term><term>Betacoronavirus</term><term>Cohort Studies</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Oxygen Inhalation Therapy</term><term>Pandemics</term><term>Prodromal Symptoms</term><term>Radiography, Thoracic</term><term>Real-Time Polymerase Chain Reaction</term><term>Retrospective Studies</term><term>Time Factors</term><term>Tomography, X-Ray Computed</term><term>Young Adult</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected pneumonia emerged in Wuhan, China in December 2019. In this retrospective multicenter study, we investigated the clinical course and outcomes of novel coronavirus disease 2019 (COVID-19) from early cases in Republic of Korea.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32242348</PMID><DateCompleted><Year>2020</Year><Month>04</Month><Day>06</Day></DateCompleted><DateRevised><Year>2020</Year><Month>04</Month><Day>09</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1598-6357</ISSN><JournalIssue CitedMedium="Internet"><Volume>35</Volume><Issue>13</Issue><PubDate><Year>2020</Year><Month>Apr</Month><Day>06</Day></PubDate></JournalIssue><Title>Journal of Korean medical science</Title><ISOAbbreviation>J. Korean Med. Sci.</ISOAbbreviation></Journal><ArticleTitle>Clinical Course and Outcomes of Patients with Severe Acute Respiratory Syndrome Coronavirus 2 Infection: a Preliminary Report of the First 28 Patients from the Korean Cohort Study on COVID-19.</ArticleTitle><Pagination><MedlinePgn>e142</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.3346/jkms.2020.35.e142</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected pneumonia emerged in Wuhan, China in December 2019. In this retrospective multicenter study, we investigated the clinical course and outcomes of novel coronavirus disease 2019 (COVID-19) from early cases in Republic of Korea.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">All of the cases confirmed by real time polymerase chain reaction were enrolled from the 1st to the 28th patient nationwide. Clinical data were collected and analyzed for changes in clinical severity including laboratory, radiological, and virologic dynamics during the progression of illness.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">The median age was 40 years (range, 20-73 years) and 15 (53.6%) patients were male. The most common symptoms were cough (28.6%) and sore throat (28.6%), followed by fever (25.0%). Diarrhea was not common (10.7%). Two patients had no symptoms. Initial chest X-ray (CXR) showed infiltration in 46.4% of the patients, but computed tomography scan confirmed pneumonia in 88.9% (16/18) of the patients. Six patients (21.4%) required supplemental oxygen therapy, but no one needed mechanical ventilation. Lymphopenia was more common in severe cases. Higher level of C-reactive protein and worsening of chest radiographic score was observed during the 5-7 day period after symptom onset. Viral shedding was high from day 1 of illness, especially from the upper respiratory tract (URT).</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The prodromal symptoms of COVID-19 were mild and most patients did not have limitations of daily activity. Viral shedding from URT was high from the prodromal phase. Radiological pneumonia was common from the early days of illness, but it was frequently not evident in simple CXR. These findings could be plausible explanations for the easy and rapid spread of SARS-CoV-2 in the community.</AbstractText><CopyrightInformation>© 2020 The Korean Academy of Medical Sciences.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y" EqualContrib="Y"><LastName>Kim</LastName><ForeName>Eu Suk</ForeName><Initials>ES</Initials><Identifier Source="ORCID">https://orcid.org/0000-0001-7132-0157</Identifier><AffiliationInfo><Affiliation>Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y" EqualContrib="Y"><LastName>Chin</LastName><ForeName>Bum Sik</ForeName><Initials>BS</Initials><Identifier Source="ORCID">https://orcid.org/0000-0003-3021-1434</Identifier><AffiliationInfo><Affiliation>Division of Infectious Diseases, Department of Internal Medicine, National Medical Center, Seoul, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kang</LastName><ForeName>Chang Kyung</ForeName><Initials>CK</Initials><Identifier Source="ORCID">https://orcid.org/0000-0003-1952-072X</Identifier><AffiliationInfo><Affiliation>Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Nam Joong</ForeName><Initials>NJ</Initials><Identifier Source="ORCID">https://orcid.org/0000-0001-6793-9467</Identifier><AffiliationInfo><Affiliation>Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kang</LastName><ForeName>Yu Min</ForeName><Initials>YM</Initials><Identifier Source="ORCID">https://orcid.org/0000-0002-4368-9878</Identifier><AffiliationInfo><Affiliation>Department of Infectious Diseases, Myongji Hospital, Goyang, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Choi</LastName><ForeName>Jae Phil</ForeName><Initials>JP</Initials><Identifier Source="ORCID">https://orcid.org/0000-0003-4805-7930</Identifier><AffiliationInfo><Affiliation>Department of Internal Medicine, Seoul Medical Center, Seoul, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Oh</LastName><ForeName>Dong Hyun</ForeName><Initials>DH</Initials><Identifier Source="ORCID">https://orcid.org/0000-0002-9990-6042</Identifier><AffiliationInfo><Affiliation>Department of Internal Medicine, Seoul Medical Center, Seoul, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Jeong Han</ForeName><Initials>JH</Initials><Identifier Source="ORCID">https://orcid.org/0000-0001-5117-4893</Identifier><AffiliationInfo><Affiliation>Division of Infectious Diseases, Department of Internal Medicine, Armed Forces Capital Hospital, Seongnam, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Koh</LastName><ForeName>Boram</ForeName><Initials>B</Initials><Identifier Source="ORCID">https://orcid.org/0000-0002-8810-1417</Identifier><AffiliationInfo><Affiliation>Department of Internal Medicine, Gyeonggi Provincial Medical Center Ansung Hospital, Anseong, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Seong Eun</ForeName><Initials>SE</Initials><Identifier Source="ORCID">https://orcid.org/0000-0003-0162-6155</Identifier><AffiliationInfo><Affiliation>Department of Infectious Diseases, Chonnam National University Medical School, Gwangju, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yun</LastName><ForeName>Na Ra</ForeName><Initials>NR</Initials><Identifier Source="ORCID">https://orcid.org/0000-0002-4219-0127</Identifier><AffiliationInfo><Affiliation>Department of Internal Medicine, College of Medicine, Chosun University, Gwangju, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lee</LastName><ForeName>Jae Hoon</ForeName><Initials>JH</Initials><Identifier Source="ORCID">https://orcid.org/0000-0002-0897-2838</Identifier><AffiliationInfo><Affiliation>Department of Internal Medicine, Wonkwang University School of Medicine, Iksan, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Jin Yong</ForeName><Initials>JY</Initials><Identifier Source="ORCID">https://orcid.org/0000-0002-4306-1597</Identifier><AffiliationInfo><Affiliation>Division of Infectious Diseases, Department of Internal Medicine, Incheon Medical Center, Incheon, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Yeonjae</ForeName><Initials>Y</Initials><Identifier Source="ORCID">https://orcid.org/0000-0003-4144-9077</Identifier><AffiliationInfo><Affiliation>Division of Infectious Diseases, Department of Internal Medicine, National Medical Center, Seoul, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bang</LastName><ForeName>Ji Hwan</ForeName><Initials>JH</Initials><Identifier Source="ORCID">https://orcid.org/0000-0002-7628-1182</Identifier><AffiliationInfo><Affiliation>Division of Infectious Diseases, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Song</LastName><ForeName>Kyoung Ho</ForeName><Initials>KH</Initials><Identifier Source="ORCID">https://orcid.org/0000-0002-4517-3840</Identifier><AffiliationInfo><Affiliation>Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Hong Bin</ForeName><Initials>HB</Initials><Identifier Source="ORCID">https://orcid.org/0000-0001-6262-372X</Identifier><AffiliationInfo><Affiliation>Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chung</LastName><ForeName>Ki Hyun</ForeName><Initials>KH</Initials><Identifier Source="ORCID">https://orcid.org/0000-0002-7100-2519</Identifier><AffiliationInfo><Affiliation>Department of Pediatrics, National Medical Center, Seoul, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Oh</LastName><ForeName>Myoung Don</ForeName><Initials>MD</Initials><Identifier Source="ORCID">https://orcid.org/0000-0002-2344-7695</Identifier><AffiliationInfo><Affiliation>Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. mdohmd@snu.ac.kr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><CollectiveName>Korea National Committee for Clinical Management of COVID-19</CollectiveName></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>2740-309-320-01</GrantID><Acronym>MHW</Acronym><Agency>Ministry of Health and Welfare</Agency><Country>Korea</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016448">Multicenter Study</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>04</Month><Day>06</Day></ArticleDate></Article><MedlineJournalInfo><Country>Korea (South)</Country><MedlineTA>J Korean Med Sci</MedlineTA><NlmUniqueID>8703518</NlmUniqueID><ISSNLinking>1011-8934</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>9007-41-4</RegistryNumber><NameOfSubstance UI="D002097">C-Reactive Protein</NameOfSubstance></Chemical></ChemicalList><SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName><SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName></SupplMeshList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058070" MajorTopicYN="N">Asymptomatic Diseases</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="Y">Betacoronavirus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002097" MajorTopicYN="N">C-Reactive Protein</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015331" MajorTopicYN="N">Cohort Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="Y">Coronavirus 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MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010102" MajorTopicYN="N">Oxygen Inhalation Therapy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058873" MajorTopicYN="Y">Pandemics</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010612" MajorTopicYN="N">Pharyngitis</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011024" MajorTopicYN="Y">Pneumonia, Viral</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000000981" MajorTopicYN="N">diagnostic imaging</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D062706" MajorTopicYN="N">Prodromal Symptoms</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013902" MajorTopicYN="N">Radiography, Thoracic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D060888" MajorTopicYN="N">Real-Time Polymerase Chain Reaction</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D056910" MajorTopicYN="N" Type="Geographic">Republic of Korea</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014057" MajorTopicYN="N">Tomography, X-Ray Computed</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">COVID-19</Keyword><Keyword MajorTopicYN="N">Cohort Study</Keyword><Keyword MajorTopicYN="N">Prognosis</Keyword><Keyword MajorTopicYN="N">Republic of Korea</Keyword><Keyword 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