SrasV1, PubMed, Corpus, bibRecord, 000302

Ocular manifestations of a hospitalised patient with confirmed 2019 novel coronavirus disease.

Identifieur interne : 000302 ( PubMed/Corpus ); précédent : 000301; suivant : 000303

Ocular manifestations of a hospitalised patient with confirmed 2019 novel coronavirus disease.

Auteurs : Lu Chen ; Meizhou Liu ; Zheng Zhang ; Kun Qiao ; Ting Huang ; Miaohong Chen ; Na Xin ; Zuliang Huang ; Lei Liu ; Guoming Zhang ; Jiantao Wang

Source :

The British journal of ophthalmology [ 1468-2079 ] ; 2020.

RBID : pubmed:32265202

Abstract

To report the ocular characteristics and the presence of viral RNA of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in conjunctival swab specimens in a patient with confirmed 2019 novel coronavirus disease (COVID-19).

DOI: 10.1136/bjophthalmol-2020-316304
PubMed: 32265202

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pubmed:32265202

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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Ocular manifestations of a hospitalised patient with confirmed 2019 novel coronavirus disease.</title>
<author><name sortKey="Chen, Lu" sort="Chen, Lu" uniqKey="Chen L" first="Lu" last="Chen">Lu Chen</name>
<affiliation><nlm:affiliation>Ophthalmology, Shenzhen Eye Hospital, Shenzhen, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Liu, Meizhou" sort="Liu, Meizhou" uniqKey="Liu M" first="Meizhou" last="Liu">Meizhou Liu</name>
<affiliation><nlm:affiliation>Ophthalmology, Shenzhen Eye Hospital, Shenzhen, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Zhang, Zheng" sort="Zhang, Zheng" uniqKey="Zhang Z" first="Zheng" last="Zhang">Zheng Zhang</name>
<affiliation><nlm:affiliation>The Third People's Hospital of Shenzhen, Shenzhen, Guangdong, China.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Qiao, Kun" sort="Qiao, Kun" uniqKey="Qiao K" first="Kun" last="Qiao">Kun Qiao</name>
<affiliation><nlm:affiliation>The Third People's Hospital of Shenzhen, Shenzhen, Guangdong, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Huang, Ting" sort="Huang, Ting" uniqKey="Huang T" first="Ting" last="Huang">Ting Huang</name>
<affiliation><nlm:affiliation>The Third People's Hospital of Shenzhen, Shenzhen, Guangdong, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chen, Miaohong" sort="Chen, Miaohong" uniqKey="Chen M" first="Miaohong" last="Chen">Miaohong Chen</name>
<affiliation><nlm:affiliation>Ophthalmology, Shenzhen Eye Hospital, Shenzhen, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Xin, Na" sort="Xin, Na" uniqKey="Xin N" first="Na" last="Xin">Na Xin</name>
<affiliation><nlm:affiliation>Ophthalmology, Shenzhen Eye Hospital, Shenzhen, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Huang, Zuliang" sort="Huang, Zuliang" uniqKey="Huang Z" first="Zuliang" last="Huang">Zuliang Huang</name>
<affiliation><nlm:affiliation>Ophthalmology, Shenzhen Eye Hospital, Shenzhen, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Liu, Lei" sort="Liu, Lei" uniqKey="Liu L" first="Lei" last="Liu">Lei Liu</name>
<affiliation><nlm:affiliation>The Third People's Hospital of Shenzhen, Shenzhen, Guangdong, China.</nlm:affiliation>
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</author>
<author><name sortKey="Zhang, Guoming" sort="Zhang, Guoming" uniqKey="Zhang G" first="Guoming" last="Zhang">Guoming Zhang</name>
<affiliation><nlm:affiliation>Ophthalmology, Shenzhen Eye Hospital, Shenzhen, China zhang-guoming@163.com.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Wang, Jiantao" sort="Wang, Jiantao" uniqKey="Wang J" first="Jiantao" last="Wang">Jiantao Wang</name>
<affiliation><nlm:affiliation>Ophthalmology, Shenzhen Eye Hospital, Shenzhen, China.</nlm:affiliation>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Ocular manifestations of a hospitalised patient with confirmed 2019 novel coronavirus disease.</title>
<author><name sortKey="Chen, Lu" sort="Chen, Lu" uniqKey="Chen L" first="Lu" last="Chen">Lu Chen</name>
<affiliation><nlm:affiliation>Ophthalmology, Shenzhen Eye Hospital, Shenzhen, China.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Liu, Meizhou" sort="Liu, Meizhou" uniqKey="Liu M" first="Meizhou" last="Liu">Meizhou Liu</name>
<affiliation><nlm:affiliation>Ophthalmology, Shenzhen Eye Hospital, Shenzhen, China.</nlm:affiliation>
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<author><name sortKey="Zhang, Zheng" sort="Zhang, Zheng" uniqKey="Zhang Z" first="Zheng" last="Zhang">Zheng Zhang</name>
<affiliation><nlm:affiliation>The Third People's Hospital of Shenzhen, Shenzhen, Guangdong, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Qiao, Kun" sort="Qiao, Kun" uniqKey="Qiao K" first="Kun" last="Qiao">Kun Qiao</name>
<affiliation><nlm:affiliation>The Third People's Hospital of Shenzhen, Shenzhen, Guangdong, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Huang, Ting" sort="Huang, Ting" uniqKey="Huang T" first="Ting" last="Huang">Ting Huang</name>
<affiliation><nlm:affiliation>The Third People's Hospital of Shenzhen, Shenzhen, Guangdong, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chen, Miaohong" sort="Chen, Miaohong" uniqKey="Chen M" first="Miaohong" last="Chen">Miaohong Chen</name>
<affiliation><nlm:affiliation>Ophthalmology, Shenzhen Eye Hospital, Shenzhen, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Xin, Na" sort="Xin, Na" uniqKey="Xin N" first="Na" last="Xin">Na Xin</name>
<affiliation><nlm:affiliation>Ophthalmology, Shenzhen Eye Hospital, Shenzhen, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Huang, Zuliang" sort="Huang, Zuliang" uniqKey="Huang Z" first="Zuliang" last="Huang">Zuliang Huang</name>
<affiliation><nlm:affiliation>Ophthalmology, Shenzhen Eye Hospital, Shenzhen, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Liu, Lei" sort="Liu, Lei" uniqKey="Liu L" first="Lei" last="Liu">Lei Liu</name>
<affiliation><nlm:affiliation>The Third People's Hospital of Shenzhen, Shenzhen, Guangdong, China.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Zhang, Guoming" sort="Zhang, Guoming" uniqKey="Zhang G" first="Guoming" last="Zhang">Guoming Zhang</name>
<affiliation><nlm:affiliation>Ophthalmology, Shenzhen Eye Hospital, Shenzhen, China zhang-guoming@163.com.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Wang, Jiantao" sort="Wang, Jiantao" uniqKey="Wang J" first="Jiantao" last="Wang">Jiantao Wang</name>
<affiliation><nlm:affiliation>Ophthalmology, Shenzhen Eye Hospital, Shenzhen, China.</nlm:affiliation>
</affiliation>
</author>
</analytic>
<series><title level="j">The British journal of ophthalmology</title>
<idno type="eISSN">1468-2079</idno>
<imprint><date when="2020" type="published">2020</date>
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<front><div type="abstract" xml:lang="en">To report the ocular characteristics and the presence of viral RNA of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in conjunctival swab specimens in a patient with confirmed 2019 novel coronavirus disease (COVID-19).</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32265202</PMID>
<DateRevised><Year>2020</Year>
<Month>04</Month>
<Day>08</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1468-2079</ISSN>
<JournalIssue CitedMedium="Internet"><PubDate><Year>2020</Year>
<Month>Apr</Month>
<Day>07</Day>
</PubDate>
</JournalIssue>
<Title>The British journal of ophthalmology</Title>
<ISOAbbreviation>Br J Ophthalmol</ISOAbbreviation>
</Journal>
<ArticleTitle>Ocular manifestations of a hospitalised patient with confirmed 2019 novel coronavirus disease.</ArticleTitle>
<ELocationID EIdType="pii" ValidYN="Y">bjophthalmol-2020-316304</ELocationID>
<ELocationID EIdType="doi" ValidYN="Y">10.1136/bjophthalmol-2020-316304</ELocationID>
<Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">To report the ocular characteristics and the presence of viral RNA of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in conjunctival swab specimens in a patient with confirmed 2019 novel coronavirus disease (COVID-19).</AbstractText>
<AbstractText Label="PARTICIPANT AND METHODS" NlmCategory="UNASSIGNED">A 30-year-old man with confirmed COVID-19 and bilateral acute conjunctivitis which occurred 13 days after illness onset. Based on detailed ophthalmic examination, reverse transcription PCR (RT-PCR) was performed to detect SARS-CoV-2 virus in conjunctival swabs. The ocular characteristics, presence of viral RNA and viral dynamics of SARS-CoV-2 in the conjunctival specimens were evaluated.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Slit lamp examination showed bilateral acute follicular conjunctivitis. RT-PCR assay demonstrated the presence of viral RNA in conjunctival specimen 13 days after onset (cycle threshold value: 31). The conjunctival swab specimens remained positive for SARS-CoV-2 on 14 and 17 days after onset. On day 19, RT-PCR result was negative for SARS-CoV-2.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">SARS-CoV-2 is capable of causing ocular complications such as viral conjunctivitis in the middle phase of illness. Precautionary measures are recommended when examining infected patients throughout the clinical course of the infection. However, conjunctival sampling might not be useful for early diagnosis because the virus may not appear initially in the conjunctiva.</AbstractText>
<CopyrightInformation>© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y" EqualContrib="Y"><LastName>Chen</LastName>
<ForeName>Lu</ForeName>
<Initials>L</Initials>
<Identifier Source="ORCID">http://orcid.org/0000-0003-1141-8288</Identifier>
<AffiliationInfo><Affiliation>Ophthalmology, Shenzhen Eye Hospital, Shenzhen, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y" EqualContrib="Y"><LastName>Liu</LastName>
<ForeName>Meizhou</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Ophthalmology, Shenzhen Eye Hospital, Shenzhen, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zhang</LastName>
<ForeName>Zheng</ForeName>
<Initials>Z</Initials>
<AffiliationInfo><Affiliation>The Third People's Hospital of Shenzhen, Shenzhen, Guangdong, China.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Qiao</LastName>
<ForeName>Kun</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>The Third People's Hospital of Shenzhen, Shenzhen, Guangdong, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Huang</LastName>
<ForeName>Ting</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>The Third People's Hospital of Shenzhen, Shenzhen, Guangdong, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chen</LastName>
<ForeName>Miaohong</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Ophthalmology, Shenzhen Eye Hospital, Shenzhen, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Xin</LastName>
<ForeName>Na</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>Ophthalmology, Shenzhen Eye Hospital, Shenzhen, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Huang</LastName>
<ForeName>Zuliang</ForeName>
<Initials>Z</Initials>
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</AffiliationInfo>
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<Author ValidYN="Y" EqualContrib="Y"><LastName>Liu</LastName>
<ForeName>Lei</ForeName>
<Initials>L</Initials>
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</AffiliationInfo>
</Author>
<Author ValidYN="Y" EqualContrib="Y"><LastName>Zhang</LastName>
<ForeName>Guoming</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Ophthalmology, Shenzhen Eye Hospital, Shenzhen, China zhang-guoming@163.com.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y" EqualContrib="Y"><LastName>Wang</LastName>
<ForeName>Jiantao</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Ophthalmology, Shenzhen Eye Hospital, Shenzhen, China.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2020</Year>
<Month>04</Month>
<Day>07</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>Br J Ophthalmol</MedlineTA>
<NlmUniqueID>0421041</NlmUniqueID>
<ISSNLinking>0007-1161</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">conjunctiva</Keyword>
<Keyword MajorTopicYN="N">infection</Keyword>
</KeywordList>
<CoiStatement>Competing interests: None declared.</CoiStatement>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year>
<Month>03</Month>
<Day>16</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2020</Year>
<Month>03</Month>
<Day>25</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2020</Year>
<Month>03</Month>
<Day>26</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2020</Year>
<Month>4</Month>
<Day>9</Day>
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<Minute>0</Minute>
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<Day>9</Day>
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<PubMedPubDate PubStatus="medline"><Year>2020</Year>
<Month>4</Month>
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<Minute>0</Minute>
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<PublicationStatus>aheadofprint</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">32265202</ArticleId>
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<ArticleId IdType="doi">10.1136/bjophthalmol-2020-316304</ArticleId>
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Ocular manifestations of a hospitalised patient with confirmed 2019 novel coronavirus disease.

Ocular manifestations of a hospitalised patient with confirmed 2019 novel coronavirus disease.

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Abstract

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