Epidemiologic and clinical characteristics of 10 children with coronavirus disease 2019 in Changsha, China.
Identifieur interne : 000049 ( PubMed/Corpus ); précédent : 000048; suivant : 000050Epidemiologic and clinical characteristics of 10 children with coronavirus disease 2019 in Changsha, China.
Auteurs : Yu-Pin Tan ; Bo-Yu Tan ; Jia Pan ; Jing Wu ; Sai-Zhen Zeng ; Hong-Yan WeiSource :
- Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology [ 1873-5967 ] ; 2020.
Abstract
The outbreak of a new coronavirus, first reported in Wuhan, China, is spreading around the world. Information on the characteristics of children with Coronavirus Disease 2019 (COVID-19) is limited.
DOI: 10.1016/j.jcv.2020.104353
PubMed: 32302953
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Epidemiologic and clinical characteristics of 10 children with coronavirus disease 2019 in Changsha, China.</title><author><name sortKey="Tan, Yu Pin" sort="Tan, Yu Pin" uniqKey="Tan Y" first="Yu-Pin" last="Tan">Yu-Pin Tan</name><affiliation><nlm:affiliation>Division of Pediatrics, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, 410005, PR China. Electronic address: tan_yupin@163.com.</nlm:affiliation></affiliation></author><author><name sortKey="Tan, Bo Yu" sort="Tan, Bo Yu" uniqKey="Tan B" first="Bo-Yu" last="Tan">Bo-Yu Tan</name><affiliation><nlm:affiliation>Division of Clinical Pharmacy, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan, 410005, PR China. Electronic address: tanboyu@hunnu.edu.cn.</nlm:affiliation></affiliation></author><author><name sortKey="Pan, Jia" sort="Pan, Jia" uniqKey="Pan J" first="Jia" last="Pan">Jia Pan</name><affiliation><nlm:affiliation>Division of Gastroenterology, Changsha Public Health Rescue Center, North Hospital of Changsha First Hospital, Changsha, 410005, PR China. Electronic address: 344845032@qq.com.</nlm:affiliation></affiliation></author><author><name sortKey="Wu, Jing" sort="Wu, Jing" uniqKey="Wu J" first="Jing" last="Wu">Jing Wu</name><affiliation><nlm:affiliation>Division of Pharmacy, College of Medicine, Hunan Normal University, Changsha, 410005, PR China; Division of Clinical Pharmacy, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan, 410005, PR China. Electronic address: 474921585@qq.com.</nlm:affiliation></affiliation></author><author><name sortKey="Zeng, Sai Zhen" sort="Zeng, Sai Zhen" uniqKey="Zeng S" first="Sai-Zhen" last="Zeng">Sai-Zhen Zeng</name><affiliation><nlm:affiliation>Division of Pediatrics, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, 410005, PR China. Electronic address: 55445321@qq.com.</nlm:affiliation></affiliation></author><author><name sortKey="Wei, Hong Yan" sort="Wei, Hong Yan" uniqKey="Wei H" first="Hong-Yan" last="Wei">Hong-Yan Wei</name><affiliation><nlm:affiliation>Division of Clinical Pharmacy, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan, 410005, PR China. Electronic address: weihongyan@hunnu.edu.cn.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32302953</idno><idno type="pmid">32302953</idno><idno type="doi">10.1016/j.jcv.2020.104353</idno><idno type="wicri:Area/PubMed/Corpus">000049</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000049</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Epidemiologic and clinical characteristics of 10 children with coronavirus disease 2019 in Changsha, China.</title><author><name sortKey="Tan, Yu Pin" sort="Tan, Yu Pin" uniqKey="Tan Y" first="Yu-Pin" last="Tan">Yu-Pin Tan</name><affiliation><nlm:affiliation>Division of Pediatrics, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, 410005, PR China. Electronic address: tan_yupin@163.com.</nlm:affiliation></affiliation></author><author><name sortKey="Tan, Bo Yu" sort="Tan, Bo Yu" uniqKey="Tan B" first="Bo-Yu" last="Tan">Bo-Yu Tan</name><affiliation><nlm:affiliation>Division of Clinical Pharmacy, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan, 410005, PR China. Electronic address: tanboyu@hunnu.edu.cn.</nlm:affiliation></affiliation></author><author><name sortKey="Pan, Jia" sort="Pan, Jia" uniqKey="Pan J" first="Jia" last="Pan">Jia Pan</name><affiliation><nlm:affiliation>Division of Gastroenterology, Changsha Public Health Rescue Center, North Hospital of Changsha First Hospital, Changsha, 410005, PR China. Electronic address: 344845032@qq.com.</nlm:affiliation></affiliation></author><author><name sortKey="Wu, Jing" sort="Wu, Jing" uniqKey="Wu J" first="Jing" last="Wu">Jing Wu</name><affiliation><nlm:affiliation>Division of Pharmacy, College of Medicine, Hunan Normal University, Changsha, 410005, PR China; Division of Clinical Pharmacy, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan, 410005, PR China. Electronic address: 474921585@qq.com.</nlm:affiliation></affiliation></author><author><name sortKey="Zeng, Sai Zhen" sort="Zeng, Sai Zhen" uniqKey="Zeng S" first="Sai-Zhen" last="Zeng">Sai-Zhen Zeng</name><affiliation><nlm:affiliation>Division of Pediatrics, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, 410005, PR China. Electronic address: 55445321@qq.com.</nlm:affiliation></affiliation></author><author><name sortKey="Wei, Hong Yan" sort="Wei, Hong Yan" uniqKey="Wei H" first="Hong-Yan" last="Wei">Hong-Yan Wei</name><affiliation><nlm:affiliation>Division of Clinical Pharmacy, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan, 410005, PR China. Electronic address: weihongyan@hunnu.edu.cn.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology</title><idno type="eISSN">1873-5967</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The outbreak of a new coronavirus, first reported in Wuhan, China, is spreading around the world. Information on the characteristics of children with Coronavirus Disease 2019 (COVID-19) is limited.</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">32302953</PMID><DateRevised><Year>2020</Year><Month>04</Month><Day>20</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1873-5967</ISSN><JournalIssue CitedMedium="Internet"><Volume>127</Volume><PubDate><Year>2020</Year><Month>Apr</Month><Day>10</Day></PubDate></JournalIssue><Title>Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology</Title><ISOAbbreviation>J. Clin. Virol.</ISOAbbreviation></Journal><ArticleTitle>Epidemiologic and clinical characteristics of 10 children with coronavirus disease 2019 in Changsha, China.</ArticleTitle><Pagination><MedlinePgn>104353</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S1386-6532(20)30095-0</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jcv.2020.104353</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">The outbreak of a new coronavirus, first reported in Wuhan, China, is spreading around the world. Information on the characteristics of children with Coronavirus Disease 2019 (COVID-19) is limited.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">In this retrospective study, we recruited 10 children infected with SARS-COV-2 from January 27 to March 10, 2020, in Changsha, China. We report the epidemiological, clinical, laboratory, and high-resolution CT findings for these children. Qualitative descriptive analysis was used to describe the key results.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Ten children were included. Three were male and seven were female. Three were from Wuhan, Hubei Province, and seven were from Changsha. All had a history of close contact with adults with COVID-19 before the onset of disease. Clinical manifestations included fever in four cases, respiratory symptoms in three cases, febrile convulsions in one case, vomiting in one case, abdominal pain in one case, and asymptomatic infection in two cases. All the children tested positive for nucleic acid in throat swabs at admission. Stool swabs of three cases were positive for nucleic acid after several days of fever. In nine children, blood routine results were normal, whereas in one case the white blood cell count was elevated. In four cases, CT findings of the lungs showed light ground-glass opacities, one case showed changes similar to bronchopneumonia, and the remaining cases were normal. All were treated with symptomatic support without complications.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Our findings indicate that intrafamily transmission may be the main form of transmission of COVID-19 in children, and persistent intestinal excretion of virus is another characteristic among children. The results of stool swab tests should be considered for discharge and release from isolation.</AbstractText><CopyrightInformation>Copyright © 2020 The Author(s). Published by Elsevier B.V. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Tan</LastName><ForeName>Yu-Pin</ForeName><Initials>YP</Initials><AffiliationInfo><Affiliation>Division of Pediatrics, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, 410005, PR China. Electronic address: tan_yupin@163.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tan</LastName><ForeName>Bo-Yu</ForeName><Initials>BY</Initials><AffiliationInfo><Affiliation>Division of Clinical Pharmacy, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan, 410005, PR China. Electronic address: tanboyu@hunnu.edu.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pan</LastName><ForeName>Jia</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Division of Gastroenterology, Changsha Public Health Rescue Center, North Hospital of Changsha First Hospital, Changsha, 410005, PR China. Electronic address: 344845032@qq.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wu</LastName><ForeName>Jing</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Division of Pharmacy, College of Medicine, Hunan Normal University, Changsha, 410005, PR China; Division of Clinical Pharmacy, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan, 410005, PR China. Electronic address: 474921585@qq.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zeng</LastName><ForeName>Sai-Zhen</ForeName><Initials>SZ</Initials><AffiliationInfo><Affiliation>Division of Pediatrics, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, 410005, PR China. Electronic address: 55445321@qq.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wei</LastName><ForeName>Hong-Yan</ForeName><Initials>HY</Initials><AffiliationInfo><Affiliation>Division of Clinical Pharmacy, The First Affiliated Hospital of Hunan Normal University (Hunan Provincial People's Hospital), Changsha, Hunan, 410005, PR China. Electronic address: weihongyan@hunnu.edu.cn.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>04</Month><Day>10</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>J Clin Virol</MedlineTA><NlmUniqueID>9815671</NlmUniqueID><ISSNLinking>1386-6532</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Clinical characteristics</Keyword><Keyword MajorTopicYN="N">Coronavirus disease 2019</Keyword><Keyword MajorTopicYN="N">Epidemiologic</Keyword><Keyword MajorTopicYN="N">SARS-COV-2</Keyword></KeywordList><CoiStatement>Declaration of Competing Interest None declared.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>03</Month><Day>19</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>04</Month><Day>03</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>4</Month><Day>18</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>4</Month><Day>18</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>4</Month><Day>18</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32302953</ArticleId><ArticleId IdType="pii">S1386-6532(20)30095-0</ArticleId><ArticleId IdType="doi">10.1016/j.jcv.2020.104353</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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