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Serological tests facilitate identification of asymptomatic SARS-CoV-2 infection in Wuhan, China.

Identifieur interne : 000005 ( PubMed/Corpus ); précédent : 000004; suivant : 000006

Serological tests facilitate identification of asymptomatic SARS-CoV-2 infection in Wuhan, China.

Auteurs : Xiaodong Wu ; Bo Fu ; Lang Chen ; Yong Feng

Source :

Journal of medical virology [ 1096-9071 ] ; 2020.

RBID : pubmed:32311142

Abstract

The Wuhan City has ended the lockdown and people have been allowed to resume working since April 8 if meeting a set of COVID-19-associated tests including SARS-CoV-2 nucleic acid test (NAT) of nasopharyngeal swabs, chest CT scan or a SARS-CoV-2-specific serological test. Here, we reported the positive rate of COVID-19 tests based on NAT, chest CT scan and a serological SARS-CoV-2 test, from April 3 to 15 in one hospital in Qingshan Destrict, Wuhan. We observed a ~10% SARS-CoV-2-specific IgG positive rate from 1,402 tests. Combination of SARS-CoV-2 NAT and a specific serological test might facilitate the detection of COVID-19 infection, or the asymptomatic SARS-CoV-2-infected subjects. Large-scale investigation is required to evaluate the herd immunity of the city, for the resuming people and for the re-opened city. This article is protected by copyright. All rights reserved.

DOI: 10.1002/jmv.25904
PubMed: 32311142

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Le document en format XML

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<author><name sortKey="Wu, Xiaodong" sort="Wu, Xiaodong" uniqKey="Wu X" first="Xiaodong" last="Wu">Xiaodong Wu</name>
<affiliation><nlm:affiliation>Department of Respiratory and Critical Care Medicine, CR & WISCO General Hospital, Wuhan, 430080, Hubei, China.</nlm:affiliation>
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<author><name sortKey="Fu, Bo" sort="Fu, Bo" uniqKey="Fu B" first="Bo" last="Fu">Bo Fu</name>
<affiliation><nlm:affiliation>Dept. of Clinical Laboratory, CR & WISCO General Hospital, Wuhan, 430080, Hubei, China.</nlm:affiliation>
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<author><name sortKey="Chen, Lang" sort="Chen, Lang" uniqKey="Chen L" first="Lang" last="Chen">Lang Chen</name>
<affiliation><nlm:affiliation>Department of Immunology, School of Basic Medical Sciences, Wuhan University, Wuhan, 430071, Hubei, China.</nlm:affiliation>
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<author><name sortKey="Feng, Yong" sort="Feng, Yong" uniqKey="Feng Y" first="Yong" last="Feng">Yong Feng</name>
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<front><div type="abstract" xml:lang="en">The Wuhan City has ended the lockdown and people have been allowed to resume working since April 8 if meeting a set of COVID-19-associated tests including SARS-CoV-2 nucleic acid test (NAT) of nasopharyngeal swabs, chest CT scan or a SARS-CoV-2-specific serological test. Here, we reported the positive rate of COVID-19 tests based on NAT, chest CT scan and a serological SARS-CoV-2 test, from April 3 to 15 in one hospital in Qingshan Destrict, Wuhan. We observed a ~10% SARS-CoV-2-specific IgG positive rate from 1,402 tests. Combination of SARS-CoV-2 NAT and a specific serological test might facilitate the detection of COVID-19 infection, or the asymptomatic SARS-CoV-2-infected subjects. Large-scale investigation is required to evaluate the herd immunity of the city, for the resuming people and for the re-opened city. This article is protected by copyright. All rights reserved.</div>
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<Abstract><AbstractText>The Wuhan City has ended the lockdown and people have been allowed to resume working since April 8 if meeting a set of COVID-19-associated tests including SARS-CoV-2 nucleic acid test (NAT) of nasopharyngeal swabs, chest CT scan or a SARS-CoV-2-specific serological test. Here, we reported the positive rate of COVID-19 tests based on NAT, chest CT scan and a serological SARS-CoV-2 test, from April 3 to 15 in one hospital in Qingshan Destrict, Wuhan. We observed a ~10% SARS-CoV-2-specific IgG positive rate from 1,402 tests. Combination of SARS-CoV-2 NAT and a specific serological test might facilitate the detection of COVID-19 infection, or the asymptomatic SARS-CoV-2-infected subjects. Large-scale investigation is required to evaluate the herd immunity of the city, for the resuming people and for the re-opened city. This article is protected by copyright. All rights reserved.</AbstractText>
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Serological tests facilitate identification of asymptomatic SARS-CoV-2 infection in Wuhan, China.

Serological tests facilitate identification of asymptomatic SARS-CoV-2 infection in Wuhan, China.

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