SrasV1, PubMed, Checkpoint, bibRecord, 002C08

Macaque model for severe acute respiratory syndrome.

Identifieur interne : 002C08 ( PubMed/Checkpoint ); précédent : 002C07; suivant : 002C09

Macaque model for severe acute respiratory syndrome.

Auteurs : Thomas Rowe [États-Unis] ; Guangping Gao ; Robert J. Hogan ; Ronald G. Crystal ; Thomas G. Voss ; Rebecca L. Grant ; Peter Bell ; Gary P. Kobinger ; Nelson A. Wivel ; James M. Wilson

Source :

Journal of virology [ 0022-538X ] ; 2004.

RBID : pubmed:15452262

Descripteurs français

KwdFr :
- Animaux, Humains, Macaca, Modèles animaux de maladie humaine, Poumon (anatomopathologie), Poumon (virologie), Syndrome respiratoire aigu sévère (anatomopathologie), Syndrome respiratoire aigu sévère (physiopathologie), Syndrome respiratoire aigu sévère (virologie), Virus du SRAS (isolement et purification), Virus du SRAS (pathogénicité).
MESH :
- anatomopathologie : Poumon, Syndrome respiratoire aigu sévère.
- isolement et purification : Virus du SRAS.
- pathogénicité : Virus du SRAS.
- physiopathologie : Syndrome respiratoire aigu sévère.
- virologie : Poumon, Syndrome respiratoire aigu sévère.
- Animaux, Humains, Macaca, Modèles animaux de maladie humaine.

English descriptors

KwdEn :
- Animals, Disease Models, Animal, Humans, Lung (pathology), Lung (virology), Macaca, SARS Virus (isolation & purification), SARS Virus (pathogenicity), Severe Acute Respiratory Syndrome (pathology), Severe Acute Respiratory Syndrome (physiopathology), Severe Acute Respiratory Syndrome (virology).
MESH :
- isolation & purification : SARS Virus.
- pathogenicity : SARS Virus.
- pathology : Lung, Severe Acute Respiratory Syndrome.
- physiopathology : Severe Acute Respiratory Syndrome.
- virology : Lung, Severe Acute Respiratory Syndrome.
- Animals, Disease Models, Animal, Humans, Macaca.

Abstract

Rhesus and cynomolgus macaques were challenged with 10(7) PFU of a clinical isolate of the severe acute respiratory syndrome (SARS) coronavirus. Some of the animals developed a mild self-limited respiratory infection very different from that observed in humans with SARS. The macaque model as it currently exists will have limited utility in the study of SARS and the evaluation of therapies.

DOI: 10.1128/JVI.78.20.11401-11404.2004
PubMed: 15452262

Affiliations:

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pubmed:15452262

Le document en format XML

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<author><name sortKey="Rowe, Thomas" sort="Rowe, Thomas" uniqKey="Rowe T" first="Thomas" last="Rowe">Thomas Rowe</name>
<affiliation wicri:level="2"><nlm:affiliation>204 Wistar, 3601 Spruce St., Philadelphia, PA 19104. wilsonjm@mail.med.upenn.edu</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<placeName><region type="state">Pennsylvanie</region>
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<wicri:cityArea>204 Wistar, 3601 Spruce St., Philadelphia</wicri:cityArea>
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<author><name sortKey="Gao, Guangping" sort="Gao, Guangping" uniqKey="Gao G" first="Guangping" last="Gao">Guangping Gao</name>
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<author><name sortKey="Hogan, Robert J" sort="Hogan, Robert J" uniqKey="Hogan R" first="Robert J" last="Hogan">Robert J. Hogan</name>
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<author><name sortKey="Crystal, Ronald G" sort="Crystal, Ronald G" uniqKey="Crystal R" first="Ronald G" last="Crystal">Ronald G. Crystal</name>
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<author><name sortKey="Voss, Thomas G" sort="Voss, Thomas G" uniqKey="Voss T" first="Thomas G" last="Voss">Thomas G. Voss</name>
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<author><name sortKey="Grant, Rebecca L" sort="Grant, Rebecca L" uniqKey="Grant R" first="Rebecca L" last="Grant">Rebecca L. Grant</name>
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<author><name sortKey="Bell, Peter" sort="Bell, Peter" uniqKey="Bell P" first="Peter" last="Bell">Peter Bell</name>
</author>
<author><name sortKey="Kobinger, Gary P" sort="Kobinger, Gary P" uniqKey="Kobinger G" first="Gary P" last="Kobinger">Gary P. Kobinger</name>
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<author><name sortKey="Wivel, Nelson A" sort="Wivel, Nelson A" uniqKey="Wivel N" first="Nelson A" last="Wivel">Nelson A. Wivel</name>
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<author><name sortKey="Wilson, James M" sort="Wilson, James M" uniqKey="Wilson J" first="James M" last="Wilson">James M. Wilson</name>
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<author><name sortKey="Kobinger, Gary P" sort="Kobinger, Gary P" uniqKey="Kobinger G" first="Gary P" last="Kobinger">Gary P. Kobinger</name>
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<author><name sortKey="Wivel, Nelson A" sort="Wivel, Nelson A" uniqKey="Wivel N" first="Nelson A" last="Wivel">Nelson A. Wivel</name>
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<author><name sortKey="Wilson, James M" sort="Wilson, James M" uniqKey="Wilson J" first="James M" last="Wilson">James M. Wilson</name>
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<term>Lung (virology)</term>
<term>Macaca</term>
<term>SARS Virus (isolation & purification)</term>
<term>SARS Virus (pathogenicity)</term>
<term>Severe Acute Respiratory Syndrome (pathology)</term>
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<term>Poumon (virologie)</term>
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<term>Syndrome respiratoire aigu sévère (physiopathologie)</term>
<term>Syndrome respiratoire aigu sévère (virologie)</term>
<term>Virus du SRAS (isolement et purification)</term>
<term>Virus du SRAS (pathogénicité)</term>
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<term>Syndrome respiratoire aigu sévère</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Lung</term>
<term>Severe Acute Respiratory Syndrome</term>
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</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Poumon</term>
<term>Syndrome respiratoire aigu sévère</term>
</keywords>
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<term>Severe Acute Respiratory Syndrome</term>
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<front><div type="abstract" xml:lang="en">Rhesus and cynomolgus macaques were challenged with 10(7) PFU of a clinical isolate of the severe acute respiratory syndrome (SARS) coronavirus. Some of the animals developed a mild self-limited respiratory infection very different from that observed in humans with SARS. The macaque model as it currently exists will have limited utility in the study of SARS and the evaluation of therapies.</div>
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<AffiliationInfo><Affiliation>204 Wistar, 3601 Spruce St., Philadelphia, PA 19104. wilsonjm@mail.med.upenn.edu</Affiliation>
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<Reference><Citation>Nature. 2003 May 15;423(6937):240</Citation>
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<Reference><Citation>Science. 2003 May 30;300(5624):1399-404</Citation>
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<Reference><Citation>Nat Med. 2004 Mar;10(3):290-3</Citation>
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<Reference><Citation>Lancet. 2003 May 24;361(9371):1773-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12781536</ArticleId>
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<Reference><Citation>Lancet. 2003 Jul 26;362(9380):263-70</Citation>
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<Reference><Citation>Lancet. 2003 May 24;361(9371):1767-72</Citation>
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<name sortKey="Gao, Guangping" sort="Gao, Guangping" uniqKey="Gao G" first="Guangping" last="Gao">Guangping Gao</name>
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<name sortKey="Hogan, Robert J" sort="Hogan, Robert J" uniqKey="Hogan R" first="Robert J" last="Hogan">Robert J. Hogan</name>
<name sortKey="Kobinger, Gary P" sort="Kobinger, Gary P" uniqKey="Kobinger G" first="Gary P" last="Kobinger">Gary P. Kobinger</name>
<name sortKey="Voss, Thomas G" sort="Voss, Thomas G" uniqKey="Voss T" first="Thomas G" last="Voss">Thomas G. Voss</name>
<name sortKey="Wilson, James M" sort="Wilson, James M" uniqKey="Wilson J" first="James M" last="Wilson">James M. Wilson</name>
<name sortKey="Wivel, Nelson A" sort="Wivel, Nelson A" uniqKey="Wivel N" first="Nelson A" last="Wivel">Nelson A. Wivel</name>
</noCountry>
<country name="États-Unis"><region name="Pennsylvanie"><name sortKey="Rowe, Thomas" sort="Rowe, Thomas" uniqKey="Rowe T" first="Thomas" last="Rowe">Thomas Rowe</name>
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Macaque model for severe acute respiratory syndrome.

Macaque model for severe acute respiratory syndrome.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki