The spectrum of pathological changes in severe acute respiratory syndrome (SARS).
Identifieur interne : 002975 ( PubMed/Checkpoint ); précédent : 002974; suivant : 002976The spectrum of pathological changes in severe acute respiratory syndrome (SARS).
Auteurs : O Y Cheung [Hong Kong] ; J W M. Chan ; C K Ng ; C K KooSource :
- Histopathology [ 0309-0167 ] ; 2004.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Alvéoles pulmonaires (anatomopathologie), Bronchopneumonie (), Bronchopneumonie (anatomopathologie), Coronavirus (isolement et purification), Coronavirus (ultrastructure), Facteurs temps, Femelle, Humains, Microscopie électronique à transmission, Mâle, Sujet âgé, Syndrome respiratoire aigu sévère (), Syndrome respiratoire aigu sévère (anatomopathologie), Syndrome respiratoire aigu sévère (virologie).
- MESH :
- anatomopathologie : Alvéoles pulmonaires, Bronchopneumonie, Syndrome respiratoire aigu sévère.
- isolement et purification : Coronavirus.
- virologie : Syndrome respiratoire aigu sévère.
- Adulte, Adulte d'âge moyen, Bronchopneumonie, Coronavirus, Facteurs temps, Femelle, Humains, Microscopie électronique à transmission, Mâle, Sujet âgé, Syndrome respiratoire aigu sévère.
English descriptors
- KwdEn :
- Adult, Aged, Bronchopneumonia (complications), Bronchopneumonia (pathology), Coronavirus (isolation & purification), Coronavirus (ultrastructure), Female, Humans, Male, Microscopy, Electron, Transmission, Middle Aged, Pulmonary Alveoli (pathology), Severe Acute Respiratory Syndrome (complications), Severe Acute Respiratory Syndrome (pathology), Severe Acute Respiratory Syndrome (virology), Time Factors.
- MESH :
- complications : Bronchopneumonia, Severe Acute Respiratory Syndrome.
- isolation & purification : Coronavirus.
- pathology : Bronchopneumonia, Pulmonary Alveoli, Severe Acute Respiratory Syndrome.
- ultrastructure : Coronavirus.
- virology : Severe Acute Respiratory Syndrome.
- Adult, Aged, Female, Humans, Male, Microscopy, Electron, Transmission, Middle Aged, Time Factors.
Abstract
To analyse the lung pathology of severe acute respiratory syndrome (SARS) and correlate the findings with the time sequence of the disease.
DOI: 10.1111/j.1365-2559.2004.01926.x
PubMed: 15279629
Affiliations:
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pubmed:15279629Le document en format XML
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Chan</name></author><author><name sortKey="Ng, C K" sort="Ng, C K" uniqKey="Ng C" first="C K" last="Ng">C K Ng</name></author><author><name sortKey="Koo, C K" sort="Koo, C K" uniqKey="Koo C" first="C K" last="Koo">C K Koo</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2004">2004</date><idno type="RBID">pubmed:15279629</idno><idno type="pmid">15279629</idno><idno type="doi">10.1111/j.1365-2559.2004.01926.x</idno><idno type="wicri:Area/PubMed/Corpus">002C43</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002C43</idno><idno type="wicri:Area/PubMed/Curation">002C43</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002C43</idno><idno type="wicri:Area/PubMed/Checkpoint">002975</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002975</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">The spectrum of pathological changes in severe acute respiratory syndrome (SARS).</title><author><name sortKey="Cheung, O Y" sort="Cheung, O Y" uniqKey="Cheung O" first="O Y" last="Cheung">O Y Cheung</name><affiliation wicri:level="1"><nlm:affiliation>Department of Pathology, Queen Elizabeth Hospital, Hong Kong. oycheung@yahoo.com</nlm:affiliation><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Department of Pathology, Queen Elizabeth Hospital</wicri:regionArea><wicri:noRegion>Queen Elizabeth Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Chan, J W M" sort="Chan, J W M" uniqKey="Chan J" first="J W M" last="Chan">J W M. Chan</name></author><author><name sortKey="Ng, C K" sort="Ng, C K" uniqKey="Ng C" first="C K" last="Ng">C K Ng</name></author><author><name sortKey="Koo, C K" sort="Koo, C K" uniqKey="Koo C" first="C K" last="Koo">C K Koo</name></author></analytic><series><title level="j">Histopathology</title><idno type="ISSN">0309-0167</idno><imprint><date when="2004" type="published">2004</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Bronchopneumonia (complications)</term><term>Bronchopneumonia (pathology)</term><term>Coronavirus (isolation & purification)</term><term>Coronavirus (ultrastructure)</term><term>Female</term><term>Humans</term><term>Male</term><term>Microscopy, Electron, Transmission</term><term>Middle Aged</term><term>Pulmonary Alveoli (pathology)</term><term>Severe Acute Respiratory Syndrome (complications)</term><term>Severe Acute Respiratory Syndrome (pathology)</term><term>Severe Acute Respiratory Syndrome (virology)</term><term>Time Factors</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Alvéoles pulmonaires (anatomopathologie)</term><term>Bronchopneumonie ()</term><term>Bronchopneumonie (anatomopathologie)</term><term>Coronavirus (isolement et purification)</term><term>Coronavirus (ultrastructure)</term><term>Facteurs temps</term><term>Femelle</term><term>Humains</term><term>Microscopie électronique à transmission</term><term>Mâle</term><term>Sujet âgé</term><term>Syndrome respiratoire aigu sévère ()</term><term>Syndrome respiratoire aigu sévère (anatomopathologie)</term><term>Syndrome respiratoire aigu sévère (virologie)</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Alvéoles pulmonaires</term><term>Bronchopneumonie</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Bronchopneumonia</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Bronchopneumonia</term><term>Pulmonary Alveoli</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="ultrastructure" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Female</term><term>Humans</term><term>Male</term><term>Microscopy, Electron, Transmission</term><term>Middle Aged</term><term>Time Factors</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Bronchopneumonie</term><term>Coronavirus</term><term>Facteurs temps</term><term>Femelle</term><term>Humains</term><term>Microscopie électronique à transmission</term><term>Mâle</term><term>Sujet âgé</term><term>Syndrome respiratoire aigu sévère</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To analyse the lung pathology of severe acute respiratory syndrome (SARS) and correlate the findings with the time sequence of the disease.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">15279629</PMID><DateCompleted><Year>2005</Year><Month>01</Month><Day>25</Day></DateCompleted><DateRevised><Year>2004</Year><Month>07</Month><Day>28</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0309-0167</ISSN><JournalIssue CitedMedium="Print"><Volume>45</Volume><Issue>2</Issue><PubDate><Year>2004</Year><Month>Aug</Month></PubDate></JournalIssue><Title>Histopathology</Title><ISOAbbreviation>Histopathology</ISOAbbreviation></Journal><ArticleTitle>The spectrum of pathological changes in severe acute respiratory syndrome (SARS).</ArticleTitle><Pagination><MedlinePgn>119-24</MedlinePgn></Pagination><Abstract><AbstractText Label="AIMS" NlmCategory="OBJECTIVE">To analyse the lung pathology of severe acute respiratory syndrome (SARS) and correlate the findings with the time sequence of the disease.</AbstractText><AbstractText Label="METHODS AND RESULTS" NlmCategory="RESULTS">Ten patients with a clinical diagnosis of SARS, and virological confirmation of SARS coronavirus infection were identified. Histology in most cases showed diffuse alveolar damage, from early to late phases, and the changes corresponded to the time sequence. Other variable features include multinucleated giant cells, pneumocytes with cytomegaly and variable amounts of inflammatory cells and foamy macrophages. One case showed superimposed bronchopneumonia. No viral inclusions were found. Coronavirus particles were identified in pneumocytes by electron microscopy.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The predominant pathological process of SARS is diffuse alveolar damage and, in patients who die from the disease, there is evidence of organization and fibrosis. There are apparently no histological features specific for this disease, and the aetiological diagnosis depends on virological and ultrastructural studies.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Cheung</LastName><ForeName>O Y</ForeName><Initials>OY</Initials><AffiliationInfo><Affiliation>Department of Pathology, Queen Elizabeth Hospital, Hong Kong. oycheung@yahoo.com</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chan</LastName><ForeName>J W M</ForeName><Initials>JW</Initials></Author><Author ValidYN="Y"><LastName>Ng</LastName><ForeName>C K</ForeName><Initials>CK</Initials></Author><Author ValidYN="Y"><LastName>Koo</LastName><ForeName>C K</ForeName><Initials>CK</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Histopathology</MedlineTA><NlmUniqueID>7704136</NlmUniqueID><ISSNLinking>0309-0167</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001996" MajorTopicYN="N">Bronchopneumonia</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017934" MajorTopicYN="N">Coronavirus</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName><QualifierName UI="Q000648" MajorTopicYN="N">ultrastructure</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D046529" MajorTopicYN="N">Microscopy, Electron, Transmission</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011650" MajorTopicYN="N">Pulmonary Alveoli</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D045169" MajorTopicYN="N">Severe Acute Respiratory Syndrome</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName><QualifierName UI="Q000821" MajorTopicYN="N">virology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2004</Year><Month>7</Month><Day>29</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2005</Year><Month>1</Month><Day>26</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2004</Year><Month>7</Month><Day>29</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">15279629</ArticleId><ArticleId IdType="doi">10.1111/j.1365-2559.2004.01926.x</ArticleId><ArticleId IdType="pii">HIS1926</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Hong Kong</li></country></list><tree><noCountry><name sortKey="Chan, J W M" sort="Chan, J W M" uniqKey="Chan J" first="J W M" last="Chan">J W M. Chan</name><name sortKey="Koo, C K" sort="Koo, C K" uniqKey="Koo C" first="C K" last="Koo">C K Koo</name><name sortKey="Ng, C K" sort="Ng, C K" uniqKey="Ng C" first="C K" last="Ng">C K Ng</name></noCountry><country name="Hong Kong"><noRegion><name sortKey="Cheung, O Y" sort="Cheung, O Y" uniqKey="Cheung O" first="O Y" last="Cheung">O Y Cheung</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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