Exogenous ACE2 expression allows refractory cell lines to support severe acute respiratory syndrome coronavirus replication.
Identifieur interne : 002716 ( PubMed/Checkpoint ); précédent : 002715; suivant : 002717Exogenous ACE2 expression allows refractory cell lines to support severe acute respiratory syndrome coronavirus replication.
Auteurs : Eric C. Mossel [États-Unis] ; Cheng Huang ; Krishna Narayanan ; Shinji Makino ; Robert B. Tesh ; C J PetersSource :
- Journal of virology [ 0022-538X ] ; 2005.
Descripteurs français
- KwdFr :
- Animaux, Carboxypeptidases (génétique), Carboxypeptidases (physiologie), Cellules Caco-2, Cellules Vero, Chats, Cricetinae, Herpestidae, Humains, Lapins, Lignée cellulaire, Peptidyl-Dipeptidase A, Récepteurs viraux (génétique), Récepteurs viraux (physiologie), Réplication virale, Souris, Suidae, Tupaia, Virus du SRAS (croissance et développement), Virus du SRAS (physiologie), Visons.
- MESH :
- croissance et développement : Virus du SRAS.
- génétique : Carboxypeptidases, Récepteurs viraux.
- physiologie : Carboxypeptidases, Récepteurs viraux, Virus du SRAS.
- Animaux, Cellules Caco-2, Cellules Vero, Chats, Cricetinae, Herpestidae, Humains, Lapins, Lignée cellulaire, Peptidyl-Dipeptidase A, Réplication virale, Souris, Suidae, Tupaia, Visons.
English descriptors
- KwdEn :
- Animals, Caco-2 Cells, Carboxypeptidases (genetics), Carboxypeptidases (physiology), Cats, Cell Line, Chlorocebus aethiops, Cricetinae, Herpestidae, Humans, Mice, Mink, Peptidyl-Dipeptidase A, Rabbits, Receptors, Virus (genetics), Receptors, Virus (physiology), SARS Virus (growth & development), SARS Virus (physiology), Swine, Tupaia, Vero Cells, Virus Replication.
- MESH :
- chemical , genetics : Carboxypeptidases, Receptors, Virus.
- chemical , physiology : Carboxypeptidases, Receptors, Virus.
- growth & development : SARS Virus.
- physiology : SARS Virus.
- Animals, Caco-2 Cells, Cats, Cell Line, Chlorocebus aethiops, Cricetinae, Herpestidae, Humans, Mice, Mink, Peptidyl-Dipeptidase A, Rabbits, Swine, Tupaia, Vero Cells, Virus Replication.
Abstract
Of 30 cell lines and primary cells examined, productive severe acute respiratory syndrome coronavirus (Urbani strain) (SARS-CoV) infection after low-multiplicity inoculation was detected in only six: three African green monkey kidney epithelial cell lines (Vero, Vero E6, and MA104), a human colon epithelial line (CaCo-2), a porcine kidney epithelial line [PK(15)], and mink lung epithelial cells (Mv 1 Lu). SARS-CoV produced a lytic infection in Vero, Vero E6, and MA104 cells, but there was no visible cytopathic effect in Caco-2, Mv 1 Lu, or PK(15) cells. Multistep growth kinetics were identical in Vero E6 and MA104 cells, with maximum titer reached 24 h postinoculation (hpi). Virus titer was maximal 96 hpi in CaCo-2 cells, and virus was continually produced from infected CaCo-2 cells for at least 6 weeks after infection. CaCo-2 was the only human cell type of 13 tested that supported efficient SARS-CoV replication. Expression of the SARS-CoV receptor, angiotensin-converting enzyme 2 (ACE2), resulted in SARS-CoV replication in all refractory cell lines examined. Titers achieved were variable and dependent upon the method of ACE2 expression.
DOI: 10.1128/JVI.79.6.3846-3850.2005
PubMed: 15731278
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:15731278Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Exogenous ACE2 expression allows refractory cell lines to support severe acute respiratory syndrome coronavirus replication.</title>
<author><name sortKey="Mossel, Eric C" sort="Mossel, Eric C" uniqKey="Mossel E" first="Eric C" last="Mossel">Eric C. Mossel</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology, Immunology, and Pathology, Colorado State University, 1619 Campus Delivery, Fort Collins, CO 80523-1619, USA. ecmossel@colostate.edu</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Microbiology, Immunology, and Pathology, Colorado State University, 1619 Campus Delivery, Fort Collins, CO 80523-1619</wicri:regionArea>
<placeName><region type="state">Colorado</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Huang, Cheng" sort="Huang, Cheng" uniqKey="Huang C" first="Cheng" last="Huang">Cheng Huang</name>
</author>
<author><name sortKey="Narayanan, Krishna" sort="Narayanan, Krishna" uniqKey="Narayanan K" first="Krishna" last="Narayanan">Krishna Narayanan</name>
</author>
<author><name sortKey="Makino, Shinji" sort="Makino, Shinji" uniqKey="Makino S" first="Shinji" last="Makino">Shinji Makino</name>
</author>
<author><name sortKey="Tesh, Robert B" sort="Tesh, Robert B" uniqKey="Tesh R" first="Robert B" last="Tesh">Robert B. Tesh</name>
</author>
<author><name sortKey="Peters, C J" sort="Peters, C J" uniqKey="Peters C" first="C J" last="Peters">C J Peters</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2005">2005</date>
<idno type="RBID">pubmed:15731278</idno>
<idno type="pmid">15731278</idno>
<idno type="doi">10.1128/JVI.79.6.3846-3850.2005</idno>
<idno type="wicri:Area/PubMed/Corpus">002874</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002874</idno>
<idno type="wicri:Area/PubMed/Curation">002874</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002874</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002716</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002716</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Exogenous ACE2 expression allows refractory cell lines to support severe acute respiratory syndrome coronavirus replication.</title>
<author><name sortKey="Mossel, Eric C" sort="Mossel, Eric C" uniqKey="Mossel E" first="Eric C" last="Mossel">Eric C. Mossel</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Microbiology, Immunology, and Pathology, Colorado State University, 1619 Campus Delivery, Fort Collins, CO 80523-1619, USA. ecmossel@colostate.edu</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Microbiology, Immunology, and Pathology, Colorado State University, 1619 Campus Delivery, Fort Collins, CO 80523-1619</wicri:regionArea>
<placeName><region type="state">Colorado</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Huang, Cheng" sort="Huang, Cheng" uniqKey="Huang C" first="Cheng" last="Huang">Cheng Huang</name>
</author>
<author><name sortKey="Narayanan, Krishna" sort="Narayanan, Krishna" uniqKey="Narayanan K" first="Krishna" last="Narayanan">Krishna Narayanan</name>
</author>
<author><name sortKey="Makino, Shinji" sort="Makino, Shinji" uniqKey="Makino S" first="Shinji" last="Makino">Shinji Makino</name>
</author>
<author><name sortKey="Tesh, Robert B" sort="Tesh, Robert B" uniqKey="Tesh R" first="Robert B" last="Tesh">Robert B. Tesh</name>
</author>
<author><name sortKey="Peters, C J" sort="Peters, C J" uniqKey="Peters C" first="C J" last="Peters">C J Peters</name>
</author>
</analytic>
<series><title level="j">Journal of virology</title>
<idno type="ISSN">0022-538X</idno>
<imprint><date when="2005" type="published">2005</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Caco-2 Cells</term>
<term>Carboxypeptidases (genetics)</term>
<term>Carboxypeptidases (physiology)</term>
<term>Cats</term>
<term>Cell Line</term>
<term>Chlorocebus aethiops</term>
<term>Cricetinae</term>
<term>Herpestidae</term>
<term>Humans</term>
<term>Mice</term>
<term>Mink</term>
<term>Peptidyl-Dipeptidase A</term>
<term>Rabbits</term>
<term>Receptors, Virus (genetics)</term>
<term>Receptors, Virus (physiology)</term>
<term>SARS Virus (growth & development)</term>
<term>SARS Virus (physiology)</term>
<term>Swine</term>
<term>Tupaia</term>
<term>Vero Cells</term>
<term>Virus Replication</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Carboxypeptidases (génétique)</term>
<term>Carboxypeptidases (physiologie)</term>
<term>Cellules Caco-2</term>
<term>Cellules Vero</term>
<term>Chats</term>
<term>Cricetinae</term>
<term>Herpestidae</term>
<term>Humains</term>
<term>Lapins</term>
<term>Lignée cellulaire</term>
<term>Peptidyl-Dipeptidase A</term>
<term>Récepteurs viraux (génétique)</term>
<term>Récepteurs viraux (physiologie)</term>
<term>Réplication virale</term>
<term>Souris</term>
<term>Suidae</term>
<term>Tupaia</term>
<term>Virus du SRAS (croissance et développement)</term>
<term>Virus du SRAS (physiologie)</term>
<term>Visons</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Carboxypeptidases</term>
<term>Receptors, Virus</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="physiology" xml:lang="en"><term>Carboxypeptidases</term>
<term>Receptors, Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="croissance et développement" xml:lang="fr"><term>Virus du SRAS</term>
</keywords>
<keywords scheme="MESH" qualifier="growth & development" xml:lang="en"><term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Carboxypeptidases</term>
<term>Récepteurs viraux</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Carboxypeptidases</term>
<term>Récepteurs viraux</term>
<term>Virus du SRAS</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>SARS Virus</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Caco-2 Cells</term>
<term>Cats</term>
<term>Cell Line</term>
<term>Chlorocebus aethiops</term>
<term>Cricetinae</term>
<term>Herpestidae</term>
<term>Humans</term>
<term>Mice</term>
<term>Mink</term>
<term>Peptidyl-Dipeptidase A</term>
<term>Rabbits</term>
<term>Swine</term>
<term>Tupaia</term>
<term>Vero Cells</term>
<term>Virus Replication</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Cellules Caco-2</term>
<term>Cellules Vero</term>
<term>Chats</term>
<term>Cricetinae</term>
<term>Herpestidae</term>
<term>Humains</term>
<term>Lapins</term>
<term>Lignée cellulaire</term>
<term>Peptidyl-Dipeptidase A</term>
<term>Réplication virale</term>
<term>Souris</term>
<term>Suidae</term>
<term>Tupaia</term>
<term>Visons</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Of 30 cell lines and primary cells examined, productive severe acute respiratory syndrome coronavirus (Urbani strain) (SARS-CoV) infection after low-multiplicity inoculation was detected in only six: three African green monkey kidney epithelial cell lines (Vero, Vero E6, and MA104), a human colon epithelial line (CaCo-2), a porcine kidney epithelial line [PK(15)], and mink lung epithelial cells (Mv 1 Lu). SARS-CoV produced a lytic infection in Vero, Vero E6, and MA104 cells, but there was no visible cytopathic effect in Caco-2, Mv 1 Lu, or PK(15) cells. Multistep growth kinetics were identical in Vero E6 and MA104 cells, with maximum titer reached 24 h postinoculation (hpi). Virus titer was maximal 96 hpi in CaCo-2 cells, and virus was continually produced from infected CaCo-2 cells for at least 6 weeks after infection. CaCo-2 was the only human cell type of 13 tested that supported efficient SARS-CoV replication. Expression of the SARS-CoV receptor, angiotensin-converting enzyme 2 (ACE2), resulted in SARS-CoV replication in all refractory cell lines examined. Titers achieved were variable and dependent upon the method of ACE2 expression.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">15731278</PMID>
<DateCompleted><Year>2005</Year>
<Month>04</Month>
<Day>05</Day>
</DateCompleted>
<DateRevised><Year>2019</Year>
<Month>12</Month>
<Day>10</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0022-538X</ISSN>
<JournalIssue CitedMedium="Print"><Volume>79</Volume>
<Issue>6</Issue>
<PubDate><Year>2005</Year>
<Month>Mar</Month>
</PubDate>
</JournalIssue>
<Title>Journal of virology</Title>
<ISOAbbreviation>J. Virol.</ISOAbbreviation>
</Journal>
<ArticleTitle>Exogenous ACE2 expression allows refractory cell lines to support severe acute respiratory syndrome coronavirus replication.</ArticleTitle>
<Pagination><MedlinePgn>3846-50</MedlinePgn>
</Pagination>
<Abstract><AbstractText>Of 30 cell lines and primary cells examined, productive severe acute respiratory syndrome coronavirus (Urbani strain) (SARS-CoV) infection after low-multiplicity inoculation was detected in only six: three African green monkey kidney epithelial cell lines (Vero, Vero E6, and MA104), a human colon epithelial line (CaCo-2), a porcine kidney epithelial line [PK(15)], and mink lung epithelial cells (Mv 1 Lu). SARS-CoV produced a lytic infection in Vero, Vero E6, and MA104 cells, but there was no visible cytopathic effect in Caco-2, Mv 1 Lu, or PK(15) cells. Multistep growth kinetics were identical in Vero E6 and MA104 cells, with maximum titer reached 24 h postinoculation (hpi). Virus titer was maximal 96 hpi in CaCo-2 cells, and virus was continually produced from infected CaCo-2 cells for at least 6 weeks after infection. CaCo-2 was the only human cell type of 13 tested that supported efficient SARS-CoV replication. Expression of the SARS-CoV receptor, angiotensin-converting enzyme 2 (ACE2), resulted in SARS-CoV replication in all refractory cell lines examined. Titers achieved were variable and dependent upon the method of ACE2 expression.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Mossel</LastName>
<ForeName>Eric C</ForeName>
<Initials>EC</Initials>
<AffiliationInfo><Affiliation>Department of Microbiology, Immunology, and Pathology, Colorado State University, 1619 Campus Delivery, Fort Collins, CO 80523-1619, USA. ecmossel@colostate.edu</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Huang</LastName>
<ForeName>Cheng</ForeName>
<Initials>C</Initials>
</Author>
<Author ValidYN="Y"><LastName>Narayanan</LastName>
<ForeName>Krishna</ForeName>
<Initials>K</Initials>
</Author>
<Author ValidYN="Y"><LastName>Makino</LastName>
<ForeName>Shinji</ForeName>
<Initials>S</Initials>
</Author>
<Author ValidYN="Y"><LastName>Tesh</LastName>
<ForeName>Robert B</ForeName>
<Initials>RB</Initials>
</Author>
<Author ValidYN="Y"><LastName>Peters</LastName>
<ForeName>C J</ForeName>
<Initials>CJ</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><GrantID>T32 AI007536</GrantID>
<Acronym>AI</Acronym>
<Agency>NIAID NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>AI007536</GrantID>
<Acronym>AI</Acronym>
<Agency>NIAID NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>AI29984</GrantID>
<Acronym>AI</Acronym>
<Agency>NIAID NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>R21 AI029984</GrantID>
<Acronym>AI</Acronym>
<Agency>NIAID NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>R01 AI029984</GrantID>
<Acronym>AI</Acronym>
<Agency>NIAID NIH HHS</Agency>
<Country>United States</Country>
</Grant>
<Grant><GrantID>N01 AI025489</GrantID>
<Acronym>AI</Acronym>
<Agency>NIAID NIH HHS</Agency>
<Country>United States</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
<PublicationType UI="D013487">Research Support, U.S. Gov't, P.H.S.</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>J Virol</MedlineTA>
<NlmUniqueID>0113724</NlmUniqueID>
<ISSNLinking>0022-538X</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D011991">Receptors, Virus</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 3.4.-</RegistryNumber>
<NameOfSubstance UI="D002268">Carboxypeptidases</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 3.4.15.1</RegistryNumber>
<NameOfSubstance UI="D007703">Peptidyl-Dipeptidase A</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 3.4.17.-</RegistryNumber>
<NameOfSubstance UI="C413524">angiotensin converting enzyme 2</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018938" MajorTopicYN="N">Caco-2 Cells</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002268" MajorTopicYN="N">Carboxypeptidases</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
<QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002415" MajorTopicYN="N">Cats</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002460" MajorTopicYN="N">Cell Line</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002522" MajorTopicYN="N">Chlorocebus aethiops</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006224" MajorTopicYN="N">Cricetinae</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008988" MajorTopicYN="N">Herpestidae</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D051379" MajorTopicYN="N">Mice</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008907" MajorTopicYN="N">Mink</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007703" MajorTopicYN="N">Peptidyl-Dipeptidase A</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011817" MajorTopicYN="N">Rabbits</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011991" MajorTopicYN="N">Receptors, Virus</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D045473" MajorTopicYN="N">SARS Virus</DescriptorName>
<QualifierName UI="Q000254" MajorTopicYN="N">growth & development</QualifierName>
<QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013552" MajorTopicYN="N">Swine</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014417" MajorTopicYN="N">Tupaia</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014709" MajorTopicYN="N">Vero Cells</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014779" MajorTopicYN="Y">Virus Replication</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2005</Year>
<Month>2</Month>
<Day>26</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2005</Year>
<Month>4</Month>
<Day>6</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2005</Year>
<Month>2</Month>
<Day>26</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">15731278</ArticleId>
<ArticleId IdType="pii">79/6/3846</ArticleId>
<ArticleId IdType="doi">10.1128/JVI.79.6.3846-3850.2005</ArticleId>
<ArticleId IdType="pmc">PMC1075706</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>Science. 2003 Oct 10;302(5643):276-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12958366</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2003 Jul 26;362(9380):293-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12892961</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2003 Nov 27;426(6965):450-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14647384</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2003 Dec 18;349(25):2431-41</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14681510</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Med. 2004 Mar;10(3):290-3</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14981511</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Pathol. 2004 Jun;203(2):631-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15141377</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virology. 2004 Jul 1;324(2):510-24</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15207636</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2004 Jun 26;363(9427):2139-41</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15220038</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Microbiol. 2004 Jul;42(7):3196-206</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15243082</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Med Virol. 2004 Sep;74(1):1-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15258961</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Emerg Infect Dis. 2004 Jul;10(7):1293-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15324552</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2004 Oct;78(19):10410-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15367607</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2004 Oct;78(20):11429-33</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15452268</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1968 Oct;2(10):955-61</Citation>
<ArticleIdList><ArticleId IdType="pubmed">4302013</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Gen Virol. 1979 Apr;43(1):247-52</Citation>
<ArticleIdList><ArticleId IdType="pubmed">113494</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Infect Immun. 1982 Jun;36(3):857-63</Citation>
<ArticleIdList><ArticleId IdType="pubmed">6178689</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 1992 Jun 4;357(6377):417-20</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1350661</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 1992 Jun 4;357(6377):420-2</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1350662</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1996 Aug;70(8):5701-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8764092</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 1996 Dec;70(12):8669-74</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8970993</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2004 Nov 2;101(44):15748-53</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15496474</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Virol. 2000 Feb;74(3):1393-406</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10627550</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7290-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10852971</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Circ Res. 2000 Sep 1;87(5):E1-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10969042</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2003 Apr 19;361(9366):1319-25</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12711465</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2003 May 15;348(20):1967-76</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12690091</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>N Engl J Med. 2003 May 15;348(20):1953-66</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12690092</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2003 May 15;423(6937):240</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12748632</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2003 Oct 30;425(6961):915</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14586458</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Colorado</li>
</region>
</list>
<tree><noCountry><name sortKey="Huang, Cheng" sort="Huang, Cheng" uniqKey="Huang C" first="Cheng" last="Huang">Cheng Huang</name>
<name sortKey="Makino, Shinji" sort="Makino, Shinji" uniqKey="Makino S" first="Shinji" last="Makino">Shinji Makino</name>
<name sortKey="Narayanan, Krishna" sort="Narayanan, Krishna" uniqKey="Narayanan K" first="Krishna" last="Narayanan">Krishna Narayanan</name>
<name sortKey="Peters, C J" sort="Peters, C J" uniqKey="Peters C" first="C J" last="Peters">C J Peters</name>
<name sortKey="Tesh, Robert B" sort="Tesh, Robert B" uniqKey="Tesh R" first="Robert B" last="Tesh">Robert B. Tesh</name>
</noCountry>
<country name="États-Unis"><region name="Colorado"><name sortKey="Mossel, Eric C" sort="Mossel, Eric C" uniqKey="Mossel E" first="Eric C" last="Mossel">Eric C. Mossel</name>
</region>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/PubMed/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002716 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 002716 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= SrasV1 |flux= PubMed |étape= Checkpoint |type= RBID |clé= pubmed:15731278 |texte= Exogenous ACE2 expression allows refractory cell lines to support severe acute respiratory syndrome coronavirus replication. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i -Sk "pubmed:15731278" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd \ | NlmPubMed2Wicri -a SrasV1
![]() | This area was generated with Dilib version V0.6.33. | ![]() |