[Expression of severe acute respiratory syndrome coronavirus receptors, ACE2 and CD209L in different organ derived microvascular endothelial cells].
Identifieur interne : 001C24 ( PubMed/Checkpoint ); précédent : 001C23; suivant : 001C25[Expression of severe acute respiratory syndrome coronavirus receptors, ACE2 and CD209L in different organ derived microvascular endothelial cells].
Auteurs : Jing Li [République populaire de Chine] ; Jie Gao ; Ya-Ping Xu ; Tong-Liang Zhou ; Yao-Ying Jin ; Jin-Ning LouSource :
- Zhonghua yi xue za zhi [ 0376-2491 ] ; 2007.
Descripteurs français
- KwdFr :
- Cellules cultivées, Cellules endothéliales (cytologie), Cellules endothéliales (métabolisme), Humains, Immunohistochimie, Lectines de type C (génétique), Lectines de type C (métabolisme), Molécules d'adhérence cellulaire (génétique), Molécules d'adhérence cellulaire (métabolisme), Peptidyl-Dipeptidase A (génétique), Peptidyl-Dipeptidase A (métabolisme), Poumon (), RT-PCR, Récepteurs de surface cellulaire (génétique), Récepteurs de surface cellulaire (métabolisme), Récepteurs viraux (génétique), Récepteurs viraux (métabolisme), Spécificité d'organe, Technique de Western, Vaisseaux sanguins (cytologie), Vaisseaux sanguins (métabolisme), Virus du SRAS (métabolisme).
- MESH :
- cytologie : Cellules endothéliales, Vaisseaux sanguins.
- génétique : Lectines de type C, Molécules d'adhérence cellulaire, Peptidyl-Dipeptidase A, Récepteurs de surface cellulaire, Récepteurs viraux.
- métabolisme : Cellules endothéliales, Lectines de type C, Molécules d'adhérence cellulaire, Peptidyl-Dipeptidase A, Récepteurs de surface cellulaire, Récepteurs viraux, Vaisseaux sanguins, Virus du SRAS.
- Cellules cultivées, Humains, Immunohistochimie, Poumon, RT-PCR, Spécificité d'organe, Technique de Western.
English descriptors
- KwdEn :
- Blood Vessels (cytology), Blood Vessels (metabolism), Blotting, Western, Cell Adhesion Molecules (genetics), Cell Adhesion Molecules (metabolism), Cells, Cultured, Endothelial Cells (cytology), Endothelial Cells (metabolism), Humans, Immunohistochemistry, Lectins, C-Type (genetics), Lectins, C-Type (metabolism), Lung (blood supply), Organ Specificity, Peptidyl-Dipeptidase A (genetics), Peptidyl-Dipeptidase A (metabolism), Receptors, Cell Surface (genetics), Receptors, Cell Surface (metabolism), Receptors, Virus (genetics), Receptors, Virus (metabolism), Reverse Transcriptase Polymerase Chain Reaction, SARS Virus (metabolism).
- MESH :
- chemical , genetics : Cell Adhesion Molecules, Lectins, C-Type, Peptidyl-Dipeptidase A, Receptors, Cell Surface, Receptors, Virus.
- blood supply : Lung.
- cytology : Blood Vessels, Endothelial Cells.
- metabolism : Blood Vessels, Cell Adhesion Molecules, Endothelial Cells, Lectins, C-Type, Peptidyl-Dipeptidase A, Receptors, Cell Surface, Receptors, Virus, SARS Virus.
- Blotting, Western, Cells, Cultured, Humans, Immunohistochemistry, Organ Specificity, Reverse Transcriptase Polymerase Chain Reaction.
Abstract
To investigate the expression of the 2 severe acute respiratory syndrome coronavirus (SARS-CoV) receptors, angiotensin-converting enzyme 2 (ACE2) and CD209L in different human organ/tissue derived microvascular endothelial cells.
PubMed: 17565868
Affiliations:
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pubmed:17565868Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">[Expression of severe acute respiratory syndrome coronavirus receptors, ACE2 and CD209L in different organ derived microvascular endothelial cells].</title><author><name sortKey="Li, Jing" sort="Li, Jing" uniqKey="Li J" first="Jing" last="Li">Jing Li</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Gao, Jie" sort="Gao, Jie" uniqKey="Gao J" first="Jie" last="Gao">Jie Gao</name></author><author><name sortKey="Xu, Ya Ping" sort="Xu, Ya Ping" uniqKey="Xu Y" first="Ya-Ping" last="Xu">Ya-Ping Xu</name></author><author><name sortKey="Zhou, Tong Liang" sort="Zhou, Tong Liang" uniqKey="Zhou T" first="Tong-Liang" last="Zhou">Tong-Liang Zhou</name></author><author><name sortKey="Jin, Yao Ying" sort="Jin, Yao Ying" uniqKey="Jin Y" first="Yao-Ying" last="Jin">Yao-Ying Jin</name></author><author><name sortKey="Lou, Jin Ning" sort="Lou, Jin Ning" uniqKey="Lou J" first="Jin-Ning" last="Lou">Jin-Ning Lou</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2007">2007</date><idno type="RBID">pubmed:17565868</idno><idno type="pmid">17565868</idno><idno type="wicri:Area/PubMed/Corpus">001D89</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001D89</idno><idno type="wicri:Area/PubMed/Curation">001D89</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001D89</idno><idno type="wicri:Area/PubMed/Checkpoint">001C24</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001C24</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[Expression of severe acute respiratory syndrome coronavirus receptors, ACE2 and CD209L in different organ derived microvascular endothelial cells].</title><author><name sortKey="Li, Jing" sort="Li, Jing" uniqKey="Li J" first="Jing" last="Li">Jing Li</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Gao, Jie" sort="Gao, Jie" uniqKey="Gao J" first="Jie" last="Gao">Jie Gao</name></author><author><name sortKey="Xu, Ya Ping" sort="Xu, Ya Ping" uniqKey="Xu Y" first="Ya-Ping" last="Xu">Ya-Ping Xu</name></author><author><name sortKey="Zhou, Tong Liang" sort="Zhou, Tong Liang" uniqKey="Zhou T" first="Tong-Liang" last="Zhou">Tong-Liang Zhou</name></author><author><name sortKey="Jin, Yao Ying" sort="Jin, Yao Ying" uniqKey="Jin Y" first="Yao-Ying" last="Jin">Yao-Ying Jin</name></author><author><name sortKey="Lou, Jin Ning" sort="Lou, Jin Ning" uniqKey="Lou J" first="Jin-Ning" last="Lou">Jin-Ning Lou</name></author></analytic><series><title level="j">Zhonghua yi xue za zhi</title><idno type="ISSN">0376-2491</idno><imprint><date when="2007" type="published">2007</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Blood Vessels (cytology)</term><term>Blood Vessels (metabolism)</term><term>Blotting, Western</term><term>Cell Adhesion Molecules (genetics)</term><term>Cell Adhesion Molecules (metabolism)</term><term>Cells, Cultured</term><term>Endothelial Cells (cytology)</term><term>Endothelial Cells (metabolism)</term><term>Humans</term><term>Immunohistochemistry</term><term>Lectins, C-Type (genetics)</term><term>Lectins, C-Type (metabolism)</term><term>Lung (blood supply)</term><term>Organ Specificity</term><term>Peptidyl-Dipeptidase A (genetics)</term><term>Peptidyl-Dipeptidase A (metabolism)</term><term>Receptors, Cell Surface (genetics)</term><term>Receptors, Cell Surface (metabolism)</term><term>Receptors, Virus (genetics)</term><term>Receptors, Virus (metabolism)</term><term>Reverse Transcriptase Polymerase Chain Reaction</term><term>SARS Virus (metabolism)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Cellules cultivées</term><term>Cellules endothéliales (cytologie)</term><term>Cellules endothéliales (métabolisme)</term><term>Humains</term><term>Immunohistochimie</term><term>Lectines de type C (génétique)</term><term>Lectines de type C (métabolisme)</term><term>Molécules d'adhérence cellulaire (génétique)</term><term>Molécules d'adhérence cellulaire (métabolisme)</term><term>Peptidyl-Dipeptidase A (génétique)</term><term>Peptidyl-Dipeptidase A (métabolisme)</term><term>Poumon ()</term><term>RT-PCR</term><term>Récepteurs de surface cellulaire (génétique)</term><term>Récepteurs de surface cellulaire (métabolisme)</term><term>Récepteurs viraux (génétique)</term><term>Récepteurs viraux (métabolisme)</term><term>Spécificité d'organe</term><term>Technique de Western</term><term>Vaisseaux sanguins (cytologie)</term><term>Vaisseaux sanguins (métabolisme)</term><term>Virus du SRAS (métabolisme)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Cell Adhesion Molecules</term><term>Lectins, C-Type</term><term>Peptidyl-Dipeptidase A</term><term>Receptors, Cell Surface</term><term>Receptors, Virus</term></keywords><keywords scheme="MESH" qualifier="blood supply" xml:lang="en"><term>Lung</term></keywords><keywords scheme="MESH" qualifier="cytologie" xml:lang="fr"><term>Cellules endothéliales</term><term>Vaisseaux sanguins</term></keywords><keywords scheme="MESH" qualifier="cytology" xml:lang="en"><term>Blood Vessels</term><term>Endothelial Cells</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Lectines de type C</term><term>Molécules d'adhérence cellulaire</term><term>Peptidyl-Dipeptidase A</term><term>Récepteurs de surface cellulaire</term><term>Récepteurs viraux</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Blood Vessels</term><term>Cell Adhesion Molecules</term><term>Endothelial Cells</term><term>Lectins, C-Type</term><term>Peptidyl-Dipeptidase A</term><term>Receptors, Cell Surface</term><term>Receptors, Virus</term><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Cellules endothéliales</term><term>Lectines de type C</term><term>Molécules d'adhérence cellulaire</term><term>Peptidyl-Dipeptidase A</term><term>Récepteurs de surface cellulaire</term><term>Récepteurs viraux</term><term>Vaisseaux sanguins</term><term>Virus du SRAS</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Blotting, Western</term><term>Cells, Cultured</term><term>Humans</term><term>Immunohistochemistry</term><term>Organ Specificity</term><term>Reverse Transcriptase Polymerase Chain Reaction</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Cellules cultivées</term><term>Humains</term><term>Immunohistochimie</term><term>Poumon</term><term>RT-PCR</term><term>Spécificité d'organe</term><term>Technique de Western</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To investigate the expression of the 2 severe acute respiratory syndrome coronavirus (SARS-CoV) receptors, angiotensin-converting enzyme 2 (ACE2) and CD209L in different human organ/tissue derived microvascular endothelial cells.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">17565868</PMID><DateCompleted><Year>2008</Year><Month>10</Month><Day>21</Day></DateCompleted><DateRevised><Year>2020</Year><Month>03</Month><Day>20</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0376-2491</ISSN><JournalIssue CitedMedium="Print"><Volume>87</Volume><Issue>12</Issue><PubDate><Year>2007</Year><Month>Mar</Month><Day>27</Day></PubDate></JournalIssue><Title>Zhonghua yi xue za zhi</Title><ISOAbbreviation>Zhonghua Yi Xue Za Zhi</ISOAbbreviation></Journal><ArticleTitle>[Expression of severe acute respiratory syndrome coronavirus receptors, ACE2 and CD209L in different organ derived microvascular endothelial cells].</ArticleTitle><Pagination><MedlinePgn>833-7</MedlinePgn></Pagination><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To investigate the expression of the 2 severe acute respiratory syndrome coronavirus (SARS-CoV) receptors, angiotensin-converting enzyme 2 (ACE2) and CD209L in different human organ/tissue derived microvascular endothelial cells.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Endothelial cells from the microvessels in human brain, lung, hepatic sennoside, fat adipose tissue, adrenal gland, esophagus, lymph nodes, and bone were culture. RT-PCR, Western blotting and immunocytochemistry were used to detect the expression of ACE2 and CD209L receptors.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Both SARS-CoV receptors of ACE2 and CD209L were expressed in the 8 organ/tissue-derived endothelial cells. The expression of ACE2 receptor was the highest in the human lung microvascular endothelial cells, and lowest in the lymphatic endothelial cells. The expression of CD209L was relatively higher in the human lymphatic endothelial cells.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The organ derived microvascular endothelial cells are the important target of SARS-CoV. The pathological injury of lung and lymph system induced by SARS-CoV may be mediated respectively by different receptors of SARS-CoV.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Jing</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing 100029, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gao</LastName><ForeName>Jie</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Xu</LastName><ForeName>Ya-ping</ForeName><Initials>YP</Initials></Author><Author ValidYN="Y"><LastName>Zhou</LastName><ForeName>Tong-liang</ForeName><Initials>TL</Initials></Author><Author ValidYN="Y"><LastName>Jin</LastName><ForeName>Yao-ying</ForeName><Initials>YY</Initials></Author><Author ValidYN="Y"><LastName>Lou</LastName><ForeName>Jin-ning</ForeName><Initials>JN</Initials></Author></AuthorList><Language>chi</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>China</Country><MedlineTA>Zhonghua Yi Xue Za Zhi</MedlineTA><NlmUniqueID>7511141</NlmUniqueID><ISSNLinking>0376-2491</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C433029">CLEC4M protein, human</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D015815">Cell Adhesion Molecules</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D037181">Lectins, C-Type</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D011956">Receptors, Cell Surface</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D011991">Receptors, Virus</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="C078034">coronavirus receptors</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 3.4.15.1</RegistryNumber><NameOfSubstance UI="D007703">Peptidyl-Dipeptidase A</NameOfSubstance></Chemical><Chemical><RegistryNumber>EC 3.4.17.-</RegistryNumber><NameOfSubstance UI="C413524">angiotensin converting enzyme 2</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D001808" MajorTopicYN="N">Blood Vessels</DescriptorName><QualifierName UI="Q000166" MajorTopicYN="N">cytology</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015153" MajorTopicYN="N">Blotting, Western</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015815" MajorTopicYN="N">Cell Adhesion Molecules</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002478" MajorTopicYN="N">Cells, Cultured</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D042783" MajorTopicYN="N">Endothelial Cells</DescriptorName><QualifierName UI="Q000166" MajorTopicYN="N">cytology</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007150" MajorTopicYN="N">Immunohistochemistry</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D037181" MajorTopicYN="N">Lectins, C-Type</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008168" MajorTopicYN="N">Lung</DescriptorName><QualifierName UI="Q000098" MajorTopicYN="N">blood supply</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009928" MajorTopicYN="N">Organ Specificity</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007703" MajorTopicYN="N">Peptidyl-Dipeptidase A</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011956" MajorTopicYN="N">Receptors, Cell Surface</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011991" MajorTopicYN="N">Receptors, Virus</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020133" MajorTopicYN="N">Reverse Transcriptase Polymerase Chain Reaction</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D045473" MajorTopicYN="N">SARS Virus</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2007</Year><Month>6</Month><Day>15</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2008</Year><Month>10</Month><Day>22</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2007</Year><Month>6</Month><Day>15</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">17565868</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li></country><settlement><li>Pékin</li></settlement></list><tree><noCountry><name sortKey="Gao, Jie" sort="Gao, Jie" uniqKey="Gao J" first="Jie" last="Gao">Jie Gao</name><name sortKey="Jin, Yao Ying" sort="Jin, Yao Ying" uniqKey="Jin Y" first="Yao-Ying" last="Jin">Yao-Ying Jin</name><name sortKey="Lou, Jin Ning" sort="Lou, Jin Ning" uniqKey="Lou J" first="Jin-Ning" last="Lou">Jin-Ning Lou</name><name sortKey="Xu, Ya Ping" sort="Xu, Ya Ping" uniqKey="Xu Y" first="Ya-Ping" last="Xu">Ya-Ping Xu</name><name sortKey="Zhou, Tong Liang" sort="Zhou, Tong Liang" uniqKey="Zhou T" first="Tong-Liang" last="Zhou">Tong-Liang Zhou</name></noCountry><country name="République populaire de Chine"><noRegion><name sortKey="Li, Jing" sort="Li, Jing" uniqKey="Li J" first="Jing" last="Li">Jing Li</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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