A decade after SARS: strategies for controlling emerging coronaviruses.
Identifieur interne : 001242 ( PubMed/Checkpoint ); précédent : 001241; suivant : 001243A decade after SARS: strategies for controlling emerging coronaviruses.
Auteurs : Rachel L. Graham [États-Unis] ; Eric F. Donaldson ; Ralph S. BaricSource :
- Nature reviews. Microbiology [ 1740-1534 ] ; 2013.
Descripteurs français
- KwdFr :
- Coronavirus (génétique), Coronavirus (isolement et purification), Coronavirus (pathogénicité), Coronavirus (physiologie), Découverte de médicament (tendances), Humains, Infections à coronavirus (), Infections à coronavirus (épidémiologie), Maladies transmissibles émergentes (), Maladies transmissibles émergentes (épidémiologie), Récepteurs viraux (métabolisme), Tropisme viral, Vaccins antiviraux (immunologie), Vaccins antiviraux (isolement et purification).
- MESH :
- génétique : Coronavirus.
- immunologie : Vaccins antiviraux.
- isolement et purification : Coronavirus, Vaccins antiviraux.
- métabolisme : Récepteurs viraux.
- pathogénicité : Coronavirus.
- physiologie : Coronavirus.
- tendances : Découverte de médicament.
- épidémiologie : Infections à coronavirus, Maladies transmissibles émergentes.
- Humains, Infections à coronavirus, Maladies transmissibles émergentes, Tropisme viral.
English descriptors
- KwdEn :
- Communicable Diseases, Emerging (epidemiology), Communicable Diseases, Emerging (prevention & control), Coronavirus (genetics), Coronavirus (isolation & purification), Coronavirus (pathogenicity), Coronavirus (physiology), Coronavirus Infections (epidemiology), Coronavirus Infections (prevention & control), Drug Discovery (trends), Humans, Receptors, Virus (metabolism), Viral Tropism, Viral Vaccines (immunology), Viral Vaccines (isolation & purification).
- MESH :
- chemical , immunology : Viral Vaccines.
- chemical , isolation & purification : Viral Vaccines.
- chemical , metabolism : Receptors, Virus.
- epidemiology : Communicable Diseases, Emerging, Coronavirus Infections.
- genetics : Coronavirus.
- isolation & purification : Coronavirus.
- pathogenicity : Coronavirus.
- physiology : Coronavirus.
- prevention & control : Communicable Diseases, Emerging, Coronavirus Infections.
- trends : Drug Discovery.
- Humans, Viral Tropism.
Abstract
Two novel coronaviruses have emerged in humans in the twenty-first century: severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV), both of which cause acute respiratory distress syndrome (ARDS) and are associated with high mortality rates. There are no clinically approved vaccines or antiviral drugs available for either of these infections; thus, the development of effective therapeutic and preventive strategies that can be readily applied to new emergent strains is a research priority. In this Review, we describe the emergence and identification of novel human coronaviruses over the past 10 years, discuss their key biological features, including tropism and receptor use, and summarize approaches for developing broadly effective vaccines.
DOI: 10.1038/nrmicro3143
PubMed: 24217413
Affiliations:
- États-Unis
- Caroline du Nord
- Chapel Hill (Caroline du Nord)
- Université de Caroline du Nord à Chapel Hill
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:24217413Le document en format XML
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There are no clinically approved vaccines or antiviral drugs available for either of these infections; thus, the development of effective therapeutic and preventive strategies that can be readily applied to new emergent strains is a research priority. In this Review, we describe the emergence and identification of novel human coronaviruses over the past 10 years, discuss their key biological features, including tropism and receptor use, and summarize approaches for developing broadly effective vaccines. </div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24217413</PMID><DateCompleted><Year>2014</Year><Month>01</Month><Day>06</Day></DateCompleted><DateRevised><Year>2020</Year><Month>03</Month><Day>27</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1740-1534</ISSN><JournalIssue CitedMedium="Internet"><Volume>11</Volume><Issue>12</Issue><PubDate><Year>2013</Year><Month>Dec</Month></PubDate></JournalIssue><Title>Nature reviews. Microbiology</Title><ISOAbbreviation>Nat. Rev. Microbiol.</ISOAbbreviation></Journal><ArticleTitle>A decade after SARS: strategies for controlling emerging coronaviruses.</ArticleTitle><Pagination><MedlinePgn>836-48</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1038/nrmicro3143</ELocationID><Abstract><AbstractText>Two novel coronaviruses have emerged in humans in the twenty-first century: severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV), both of which cause acute respiratory distress syndrome (ARDS) and are associated with high mortality rates. There are no clinically approved vaccines or antiviral drugs available for either of these infections; thus, the development of effective therapeutic and preventive strategies that can be readily applied to new emergent strains is a research priority. 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