AVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses.
Identifieur interne : 001052 ( PubMed/Checkpoint ); précédent : 001051; suivant : 001053AVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses.
Auteurs : Abid Qureshi [Inde] ; Nishant Thakur ; Himani Tandon ; Manoj KumarSource :
- Nucleic acids research [ 1362-4962 ] ; 2014.
Descripteurs français
- KwdFr :
- MESH :
- pharmacologie : Antiviraux, Peptides.
- Antiviraux, Bases de données chimiques, Internet, Logiciel, Peptides.
English descriptors
- KwdEn :
- MESH :
- chemical , chemistry : Antiviral Agents, Peptides.
- chemical , pharmacology : Antiviral Agents, Peptides.
- Databases, Chemical, Internet, Software.
Abstract
Antiviral peptides (AVPs) have exhibited huge potential in inhibiting viruses by targeting various stages of their life cycle. Therefore, we have developed AVPdb, available online at http://crdd.osdd.net/servers/avpdb, to provide a dedicated resource of experimentally verified AVPs targeting over 60 medically important viruses including Influenza, HCV, HSV, RSV, HBV, DENV, SARS, etc. However, we have separately provided HIV inhibiting peptides in 'HIPdb'. AVPdb contains detailed information of 2683 peptides, including 624 modified peptides experimentally tested for antiviral activity. In modified peptides a chemical moiety is attached for increasing their efficacy and stability. Detailed information include: peptide sequence, length, source, virus targeted, virus family, cell line used, efficacy (qualitative/quantitative), target step/protein, assay used in determining the efficacy and PubMed reference. The database also furnishes physicochemical properties and predicted structure for each peptide. We have provided user-friendly browsing and search facility along with other analysis tools to help the users. Entering of many synthetic peptide-based drugs in various stages of clinical trials reiterate the importance for the AVP resources. AVPdb is anticipated to cater to the needs of scientific community working for the development of antiviral therapeutics.
DOI: 10.1093/nar/gkt1191
PubMed: 24285301
Affiliations:
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Therefore, we have developed AVPdb, available online at http://crdd.osdd.net/servers/avpdb, to provide a dedicated resource of experimentally verified AVPs targeting over 60 medically important viruses including Influenza, HCV, HSV, RSV, HBV, DENV, SARS, etc. However, we have separately provided HIV inhibiting peptides in 'HIPdb'. AVPdb contains detailed information of 2683 peptides, including 624 modified peptides experimentally tested for antiviral activity. In modified peptides a chemical moiety is attached for increasing their efficacy and stability. Detailed information include: peptide sequence, length, source, virus targeted, virus family, cell line used, efficacy (qualitative/quantitative), target step/protein, assay used in determining the efficacy and PubMed reference. The database also furnishes physicochemical properties and predicted structure for each peptide. We have provided user-friendly browsing and search facility along with other analysis tools to help the users. Entering of many synthetic peptide-based drugs in various stages of clinical trials reiterate the importance for the AVP resources. AVPdb is anticipated to cater to the needs of scientific community working for the development of antiviral therapeutics. </div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24285301</PMID><DateCompleted><Year>2014</Year><Month>03</Month><Day>17</Day></DateCompleted><DateRevised><Year>2018</Year><Month>11</Month><Day>13</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1362-4962</ISSN><JournalIssue CitedMedium="Internet"><Volume>42</Volume><Issue>Database issue</Issue><PubDate><Year>2014</Year><Month>Jan</Month></PubDate></JournalIssue><Title>Nucleic acids research</Title><ISOAbbreviation>Nucleic Acids Res.</ISOAbbreviation></Journal><ArticleTitle>AVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses.</ArticleTitle><Pagination><MedlinePgn>D1147-53</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1093/nar/gkt1191</ELocationID><Abstract><AbstractText>Antiviral peptides (AVPs) have exhibited huge potential in inhibiting viruses by targeting various stages of their life cycle. Therefore, we have developed AVPdb, available online at http://crdd.osdd.net/servers/avpdb, to provide a dedicated resource of experimentally verified AVPs targeting over 60 medically important viruses including Influenza, HCV, HSV, RSV, HBV, DENV, SARS, etc. However, we have separately provided HIV inhibiting peptides in 'HIPdb'. AVPdb contains detailed information of 2683 peptides, including 624 modified peptides experimentally tested for antiviral activity. In modified peptides a chemical moiety is attached for increasing their efficacy and stability. Detailed information include: peptide sequence, length, source, virus targeted, virus family, cell line used, efficacy (qualitative/quantitative), target step/protein, assay used in determining the efficacy and PubMed reference. The database also furnishes physicochemical properties and predicted structure for each peptide. We have provided user-friendly browsing and search facility along with other analysis tools to help the users. Entering of many synthetic peptide-based drugs in various stages of clinical trials reiterate the importance for the AVP resources. 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7;97(23):12411-2</Citation><ArticleIdList><ArticleId IdType="pubmed">11035785</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2012 Jul;40(Web Server issue):W288-93</Citation><ArticleIdList><ArticleId IdType="pubmed">22581768</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2013 Jun 18;8(6):e66557</Citation><ArticleIdList><ArticleId IdType="pubmed">23825543</ArticleId></ArticleIdList></Reference><Reference><Citation>J Mol Biol. 2009 Dec 11;394(4):600-5</Citation><ArticleIdList><ArticleId IdType="pubmed">19853613</ArticleId></ArticleIdList></Reference><Reference><Citation>J Antimicrob Chemother. 2004 Aug;54(2):299-302</Citation><ArticleIdList><ArticleId IdType="pubmed">15254023</ArticleId></ArticleIdList></Reference><Reference><Citation>Molecules. 2011;16(5):3499-518</Citation><ArticleIdList><ArticleId IdType="pubmed">21522083</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Clin Pract. 2003 Dec;57(10):890-7</Citation><ArticleIdList><ArticleId IdType="pubmed">14712892</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2011;6(10):e25917</Citation><ArticleIdList><ArticleId IdType="pubmed">22022467</ArticleId></ArticleIdList></Reference><Reference><Citation>Vet Res. 2010 Nov-Dec;41(6):38</Citation><ArticleIdList><ArticleId IdType="pubmed">20167200</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Drug Discov. 2012 Jan;11(1):37-51</Citation><ArticleIdList><ArticleId IdType="pubmed">22173434</ArticleId></ArticleIdList></Reference><Reference><Citation>Cell Mol Life Sci. 2005 Dec;62(24):3002-13</Citation><ArticleIdList><ArticleId IdType="pubmed">16261265</ArticleId></ArticleIdList></Reference><Reference><Citation>Nature. 2002 Jan 24;415(6870):389-95</Citation><ArticleIdList><ArticleId IdType="pubmed">11807545</ArticleId></ArticleIdList></Reference><Reference><Citation>Curr Pharm Des. 2010;16(28):3185-203</Citation><ArticleIdList><ArticleId IdType="pubmed">20687878</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2009 Jan;37(Database issue):D933-7</Citation><ArticleIdList><ArticleId IdType="pubmed">18957441</ArticleId></ArticleIdList></Reference><Reference><Citation>Protein Pept Lett. 2007;14(7):626-31</Citation><ArticleIdList><ArticleId IdType="pubmed">17897087</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Antimicrob Agents. 2012 Apr;39(4):346-51</Citation><ArticleIdList><ArticleId IdType="pubmed">22325123</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2012 Jan;40(Database issue):D230-6</Citation><ArticleIdList><ArticleId IdType="pubmed">22139916</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2010 Jan;38(Database issue):D774-80</Citation><ArticleIdList><ArticleId IdType="pubmed">19923233</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2008 Jan;36(Database issue):D202-5</Citation><ArticleIdList><ArticleId IdType="pubmed">17998252</ArticleId></ArticleIdList></Reference><Reference><Citation>J Virol. 2001 Mar;75(6):2634-45</Citation><ArticleIdList><ArticleId IdType="pubmed">11222686</ArticleId></ArticleIdList></Reference><Reference><Citation>Biomaterials. 2013 Apr;34(13):3511-22</Citation><ArticleIdList><ArticleId IdType="pubmed">23415044</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Microbiol Rev. 2003 Jan;16(1):114-28</Citation><ArticleIdList><ArticleId IdType="pubmed">12525428</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2013;8(1):e54908</Citation><ArticleIdList><ArticleId IdType="pubmed">23359817</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Biotechnol. 2006 Dec;24(12):1551-7</Citation><ArticleIdList><ArticleId IdType="pubmed">17160061</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Rev Genet. 2008 Apr;9(4):267-76</Citation><ArticleIdList><ArticleId IdType="pubmed">18319742</ArticleId></ArticleIdList></Reference><Reference><Citation>J Med Chem. 2012 Aug 9;55(15):6881-7</Citation><ArticleIdList><ArticleId IdType="pubmed">22780881</ArticleId></ArticleIdList></Reference><Reference><Citation>Nucleic Acids Res. 2012 Jul;40(Web Server issue):W199-204</Citation><ArticleIdList><ArticleId IdType="pubmed">22638580</ArticleId></ArticleIdList></Reference><Reference><Citation>Clin Vaccine Immunol. 2006 Aug;13(8):944-52</Citation><ArticleIdList><ArticleId IdType="pubmed">16893996</ArticleId></ArticleIdList></Reference><Reference><Citation>C R Seances Soc Biol Fil. 1985;179(3):414-9</Citation><ArticleIdList><ArticleId IdType="pubmed">3002570</ArticleId></ArticleIdList></Reference><Reference><Citation>J Gen Virol. 2012 May;93(Pt 5):980-6</Citation><ArticleIdList><ArticleId 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