SrasV1, PubMed, Checkpoint, bibRecord, 000F55

Phagocytic cells contribute to the antibody-mediated elimination of pulmonary-infected SARS coronavirus.

Identifieur interne : 000F55 ( PubMed/Checkpoint ); précédent : 000F54; suivant : 000F56

Phagocytic cells contribute to the antibody-mediated elimination of pulmonary-infected SARS coronavirus.

Auteurs : Fumihiko Yasui [Japon] ; Michinori Kohara [Japon] ; Masahiro Kitabatake [Japon] ; Tetsu Nishiwaki [Japon] ; Hideki Fujii [Japon] ; Chise Tateno [Japon] ; Misako Yoneda [Japon] ; Kouichi Morita [Japon] ; Kouji Matsushima [Japon] ; Shigeo Koyasu [Japon] ; Chieko Kai [Japon]

Source :

Virology [ 1096-0341 ] ; 2014.

RBID : pubmed:24725942

Descripteurs français

English descriptors

KwdEn :
- Adoptive Transfer, Animals, Antibodies, Neutralizing (immunology), Antibodies, Viral (immunology), B-Lymphocytes (immunology), CD4-Positive T-Lymphocytes (immunology), Disease Models, Animal, Female, Immunization, Passive, Lung (immunology), Mice, Mice, Inbred BALB C, Mice, SCID, Phagocytes (immunology), SARS Virus (immunology), Severe Acute Respiratory Syndrome (immunology).
MESH :
- chemical , immunology : Antibodies, Neutralizing, Antibodies, Viral.
- immunology : B-Lymphocytes, CD4-Positive T-Lymphocytes, Lung, Phagocytes, SARS Virus, Severe Acute Respiratory Syndrome.
- Adoptive Transfer, Animals, Disease Models, Animal, Female, Immunization, Passive, Mice, Mice, Inbred BALB C, Mice, SCID.

Abstract

While the 2002-2003 outbreak of severe acute respiratory syndrome (SARS) resulted in 774 deaths, patients who were affected with mild pulmonary symptoms successfully recovered. The objective of the present work was to identify, using SARS coronavirus (SARS-CoV) mouse infection models, immune factors responsible for clearing of the virus. The elimination of pulmonary SARS-CoV infection required the activation of B cells by CD4(+) T cells. Furthermore, passive immunization (post-infection) with homologous (murine) anti-SARS-CoV antiserum showed greater elimination efficacy against SARS-CoV than that with heterologous (rabbit) antiserum, despite the use of equivalent titers of neutralizing antibodies. This distinction was mediated by mouse phagocytic cells (monocyte-derived infiltrating macrophages and partially alveolar macrophages, but not neutrophils), as demonstrated both by adoptive transfer from donors and by immunological depletion of selected cell types. These results indicate that the cooperation of anti-SARS-CoV antibodies and phagocytic cells plays an important role in the elimination of SARS-CoV.

DOI: 10.1016/j.virol.2014.02.005
PubMed: 24725942

Affiliations:

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<term>Animals</term>
<term>Antibodies, Neutralizing (immunology)</term>
<term>Antibodies, Viral (immunology)</term>
<term>B-Lymphocytes (immunology)</term>
<term>CD4-Positive T-Lymphocytes (immunology)</term>
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<term>Immunization, Passive</term>
<term>Lung (immunology)</term>
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<term>Mice, SCID</term>
<term>Phagocytes (immunology)</term>
<term>SARS Virus (immunology)</term>
<term>Severe Acute Respiratory Syndrome (immunology)</term>
</keywords>
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<term>Immunisation passive</term>
<term>Lymphocytes B (immunologie)</term>
<term>Lymphocytes T CD4+ (immunologie)</term>
<term>Modèles animaux de maladie humaine</term>
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<term>Poumon (immunologie)</term>
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<term>Souris de lignée BALB C</term>
<term>Syndrome respiratoire aigu sévère (immunologie)</term>
<term>Transfert adoptif</term>
<term>Virus du SRAS (immunologie)</term>
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<term>Anticorps neutralisants</term>
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<term>Phagocytes</term>
<term>Poumon</term>
<term>Syndrome respiratoire aigu sévère</term>
<term>Virus du SRAS</term>
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<term>CD4-Positive T-Lymphocytes</term>
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<term>Phagocytes</term>
<term>SARS Virus</term>
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<front><div type="abstract" xml:lang="en">While the 2002-2003 outbreak of severe acute respiratory syndrome (SARS) resulted in 774 deaths, patients who were affected with mild pulmonary symptoms successfully recovered. The objective of the present work was to identify, using SARS coronavirus (SARS-CoV) mouse infection models, immune factors responsible for clearing of the virus. The elimination of pulmonary SARS-CoV infection required the activation of B cells by CD4(+) T cells. Furthermore, passive immunization (post-infection) with homologous (murine) anti-SARS-CoV antiserum showed greater elimination efficacy against SARS-CoV than that with heterologous (rabbit) antiserum, despite the use of equivalent titers of neutralizing antibodies. This distinction was mediated by mouse phagocytic cells (monocyte-derived infiltrating macrophages and partially alveolar macrophages, but not neutrophils), as demonstrated both by adoptive transfer from donors and by immunological depletion of selected cell types. These results indicate that the cooperation of anti-SARS-CoV antibodies and phagocytic cells plays an important role in the elimination of SARS-CoV.</div>
</front>
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<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24725942</PMID>
<DateCompleted><Year>2014</Year>
<Month>06</Month>
<Day>02</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>04</Month>
<Day>07</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1096-0341</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>454-455</Volume>
<PubDate><Year>2014</Year>
<Month>Apr</Month>
</PubDate>
</JournalIssue>
<Title>Virology</Title>
<ISOAbbreviation>Virology</ISOAbbreviation>
</Journal>
<ArticleTitle>Phagocytic cells contribute to the antibody-mediated elimination of pulmonary-infected SARS coronavirus.</ArticleTitle>
<Pagination><MedlinePgn>157-68</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.virol.2014.02.005</ELocationID>
<ELocationID EIdType="pii" ValidYN="Y">S0042-6822(14)00049-X</ELocationID>
<Abstract><AbstractText>While the 2002-2003 outbreak of severe acute respiratory syndrome (SARS) resulted in 774 deaths, patients who were affected with mild pulmonary symptoms successfully recovered. The objective of the present work was to identify, using SARS coronavirus (SARS-CoV) mouse infection models, immune factors responsible for clearing of the virus. The elimination of pulmonary SARS-CoV infection required the activation of B cells by CD4(+) T cells. Furthermore, passive immunization (post-infection) with homologous (murine) anti-SARS-CoV antiserum showed greater elimination efficacy against SARS-CoV than that with heterologous (rabbit) antiserum, despite the use of equivalent titers of neutralizing antibodies. This distinction was mediated by mouse phagocytic cells (monocyte-derived infiltrating macrophages and partially alveolar macrophages, but not neutrophils), as demonstrated both by adoptive transfer from donors and by immunological depletion of selected cell types. These results indicate that the cooperation of anti-SARS-CoV antibodies and phagocytic cells plays an important role in the elimination of SARS-CoV.</AbstractText>
<CopyrightInformation>Copyright © 2014 Elsevier Inc. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Yasui</LastName>
<ForeName>Fumihiko</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kohara</LastName>
<ForeName>Michinori</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan. Electronic address: kohara-mc@igakuken.or.jp.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kitabatake</LastName>
<ForeName>Masahiro</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Immunology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-8556, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Nishiwaki</LastName>
<ForeName>Tetsu</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Department of Molecular Preventive Medicine, School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fujii</LastName>
<ForeName>Hideki</ForeName>
<Initials>H</Initials>
<AffiliationInfo><Affiliation>Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan; Department of Immunology, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara-cho, Okinawa 903-0213, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Tateno</LastName>
<ForeName>Chise</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>PhoenixBio Co., Ltd., 3-4-1 Kagamiyama, Higashihiroshima 739-0046, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Yoneda</LastName>
<ForeName>Misako</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Laboratory Animal Research Center, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Morita</LastName>
<ForeName>Kouichi</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Department of Virology, Institute of Tropical Medicine, Nagasaki University, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Matsushima</LastName>
<ForeName>Kouji</ForeName>
<Initials>K</Initials>
<AffiliationInfo><Affiliation>Department of Molecular Preventive Medicine, School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Koyasu</LastName>
<ForeName>Shigeo</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan; Laboratory for Immune Cell System, RCAI, RIKEN Research Center for Integrative Medical Sciences (IMS-RCAI), 1-7-22 Suehiro-cho, Yokohama 230-0045, Japan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kai</LastName>
<ForeName>Chieko</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Laboratory Animal Research Center, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2014</Year>
<Month>03</Month>
<Day>04</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Virology</MedlineTA>
<NlmUniqueID>0110674</NlmUniqueID>
<ISSNLinking>0042-6822</ISSNLinking>
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<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D057134">Antibodies, Neutralizing</NameOfSubstance>
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<NameOfSubstance UI="D000914">Antibodies, Viral</NameOfSubstance>
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<CommentsCorrectionsList><CommentsCorrections RefType="ErratumIn"><RefSource>Virology. 2016 Dec;499:397-398</RefSource>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D019264" MajorTopicYN="N">Adoptive Transfer</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D057134" MajorTopicYN="N">Antibodies, Neutralizing</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000914" MajorTopicYN="N">Antibodies, Viral</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
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<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015496" MajorTopicYN="N">CD4-Positive T-Lymphocytes</DescriptorName>
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</MeshHeading>
<MeshHeading><DescriptorName UI="D004195" MajorTopicYN="N">Disease Models, Animal</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007116" MajorTopicYN="N">Immunization, Passive</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008168" MajorTopicYN="N">Lung</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D051379" MajorTopicYN="N">Mice</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008807" MajorTopicYN="N">Mice, Inbred BALB C</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016513" MajorTopicYN="N">Mice, SCID</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010586" MajorTopicYN="N">Phagocytes</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D045473" MajorTopicYN="N">SARS Virus</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
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<MeshHeading><DescriptorName UI="D045169" MajorTopicYN="N">Severe Acute Respiratory Syndrome</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
</MeshHeading>
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<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Antibody</Keyword>
<Keyword MajorTopicYN="N">B cells</Keyword>
<Keyword MajorTopicYN="N">CD4(+) T cells</Keyword>
<Keyword MajorTopicYN="N">Elimination</Keyword>
<Keyword MajorTopicYN="N">Phagocytic cells</Keyword>
<Keyword MajorTopicYN="N">SARS-CoV</Keyword>
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<Month>01</Month>
<Day>10</Day>
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<ArticleIdList><ArticleId IdType="pubmed">24725942</ArticleId>
<ArticleId IdType="pii">S0042-6822(14)00049-X</ArticleId>
<ArticleId IdType="doi">10.1016/j.virol.2014.02.005</ArticleId>
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</ArticleIdList>
<ReferenceList><Reference><Citation>J Med Virol. 2005 Feb;75(2):185-94</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15602737</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Gen Virol. 2007 Oct;88(Pt 10):2740-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17872527</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Clin Immunol. 2006 Aug;120(2):171-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16781892</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Immunol. 2008 Oct 15;181(8):5490-500</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18832706</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Pediatr Infect Dis J. 2007 Jan;26(1):68-74</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17195709</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2010 Feb;84(3):1289-301</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19906920</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Nature. 2004 Apr 1;428(6982):561-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15024391</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Immunol. 2001 Jun 15;166(12):7381-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11390489</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2010 Sep;84(18):9318-25</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20610717</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2007 Aug;81(16):8692-706</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17537853</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Immunol Cell Biol. 2009 Jan;87(1):30-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19048016</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):284-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21173243</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):5135-40</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10220431</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Vaccine. 2007 Jan 8;25(4):729-40</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17049691</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2008 May;82(9):4441-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18287232</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Infect Dis. 2010 Mar 15;201(6):946-55</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20144042</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>N Engl J Med. 2003 May 15;348(20):1986-94</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12682352</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Lancet. 2003 May 24;361(9371):1767-72</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12781535</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Arch Virol. 2009;154(7):1093-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19526193</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Immunol. 2002 Jun 1;168(11):5954-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12023402</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Emerg Infect Dis. 2005 Mar;11(3):411-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15757556</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Leukoc Biol. 2008 Jan;83(1):64-70</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17884993</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Clin Invest. 2011 Dec;121(12):4921-30</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22105170</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Viral Immunol. 2007 Sep;20(3):495-502</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17931120</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Immunity. 2003 Jul;19(1):71-82</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12871640</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Immunol. 2008 Feb 15;180(4):2562-72</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18250467</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Blood. 2004 Feb 15;103(4):1408-16</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14563644</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Hum Pathol. 2003 Aug;34(8):743-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14506633</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Am J Pathol. 2008 Jun;172(6):1625-37</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18467696</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>PLoS Pathog. 2009 Oct;5(10):e1000636</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19851468</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12123-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17620608</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2004 Apr;78(7):3572-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15016880</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>JAMA. 2003 Jul 16;290(3):367-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12865378</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Exp Med. 1993 Sep 1;178(3):1103-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8350049</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2012 Nov;86(21):11416-24</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22915814</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Vaccine. 2007 Jan 8;25(4):630-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17011679</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Emerg Infect Dis. 2005 Nov;11(11):1730-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16318725</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Exp Med. 2006 Dec 25;203(13):2865-77</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17158960</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>PLoS Pathog. 2007 Jan;3(1):e5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17222058</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2005 May;79(9):5833-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15827197</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Clin Microbiol. 2004 May;42(5):1956-61</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15131154</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2008 Mar;82(6):2772-83</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18184718</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2008 Apr;82(7):3220-35</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18199635</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Curr Opin Infect Dis. 2004 Apr;17(2):143-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15021055</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>N Engl J Med. 2003 Dec 18;349(25):2431-41</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14681510</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Invest Ophthalmol Vis Sci. 1992 Jun;33(7):2212-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1607231</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Virol. 2005 Dec;79(23):14933-44</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16282492</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Nat Med. 2004 Dec;10(12 Suppl):S88-97</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15577937</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Lancet. 2003 May 24;361(9371):1773-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12781536</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>Clin Exp Immunol. 2004 Apr;136(1):95-103</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15030519</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
<ReferenceList><Reference><Citation>J Immunol. 2008 Nov 1;181(9):6337-48</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18941225</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
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</region>
<settlement><li>Tokyo</li>
</settlement>
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</orgName>
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Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/PubMed/Checkpoint

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000F55 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 000F55 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    SrasV1
   |flux=    PubMed
   |étape=   Checkpoint
   |type=    RBID
   |clé=     pubmed:24725942
   |texte=   Phagocytic cells contribute to the antibody-mediated elimination of pulmonary-infected SARS coronavirus.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i   -Sk "pubmed:24725942" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd   \
       | NlmPubMed2Wicri -a SrasV1

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 28 14:49:16 2020. Site generation: Sat Mar 27 22:06:49 2021

	Serveur d'exploration SRAS
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Serveur d'exploration SRAS

Phagocytic cells contribute to the antibody-mediated elimination of pulmonary-infected SARS coronavirus.

Phagocytic cells contribute to the antibody-mediated elimination of pulmonary-infected SARS coronavirus.

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Pour générer des pages wiki