Detection of viral acute lower respiratory tract infection in hospitalized infants using real-time PCR.
Identifieur interne : 000C71 ( PubMed/Checkpoint ); précédent : 000C70; suivant : 000C72Detection of viral acute lower respiratory tract infection in hospitalized infants using real-time PCR.
Auteurs : Bassant Meligy [Égypte] ; Amal Sayed [Égypte] ; Dalia Kadry Ismail [Égypte] ; Dina Kamal [Égypte] ; Walaa Abdel-Latif [Égypte] ; Dina M. Erfan [Égypte]Source :
- The Gazette of the Egyptian Paediatric Association [ 1110-6638 ] ; 2016.
Abstract
Acute lower respiratory tract infection in children causes significant morbidity in the developing countries. Documentation of virus infection using PCR and clinical characteristics of patients affected with viral pneumonia are reviewed in this study.
DOI: 10.1016/j.epag.2015.11.005
PubMed: 32288487
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Erfan</name><affiliation wicri:level="1"><nlm:affiliation>Medical Microbiology and Immunology Department, Faculty of Medicine, Ain Shams University, Egypt.</nlm:affiliation><country xml:lang="fr">Égypte</country><wicri:regionArea>Medical Microbiology and Immunology Department, Faculty of Medicine, Ain Shams University</wicri:regionArea><wicri:noRegion>Ain Shams University</wicri:noRegion></affiliation></author></analytic><series><title level="j">The Gazette of the Egyptian Paediatric Association</title><idno type="ISSN">1110-6638</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Acute lower respiratory tract infection in children causes significant morbidity in the developing countries. Documentation of virus infection using PCR and clinical characteristics of patients affected with viral pneumonia are reviewed in this study.</div></front></TEI><pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">32288487</PMID><DateRevised><Year>2020</Year><Month>04</Month><Day>18</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">1110-6638</ISSN><JournalIssue CitedMedium="Print"><Volume>64</Volume><Issue>1</Issue><PubDate><Year>2016</Year><Month>Mar</Month></PubDate></JournalIssue><Title>The Gazette of the Egyptian Paediatric Association</Title><ISOAbbreviation>Gaz Egypt Paediatr Assoc</ISOAbbreviation></Journal><ArticleTitle>Detection of viral acute lower respiratory tract infection in hospitalized infants using real-time PCR.</ArticleTitle><Pagination><MedlinePgn>13-19</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.epag.2015.11.005</ELocationID><Abstract><AbstractText Label="Introduction" NlmCategory="UNASSIGNED">Acute lower respiratory tract infection in children causes significant morbidity in the developing countries. Documentation of virus infection using PCR and clinical characteristics of patients affected with viral pneumonia are reviewed in this study.</AbstractText><AbstractText Label="Methods" NlmCategory="UNASSIGNED">51 children less than three years admitted to the Pediatric Hospital, Cairo University with viral pneumonia were included. All patients had undergone nasopharyngeal aspirate for PCR viral detection.</AbstractText><AbstractText Label="Results" NlmCategory="UNASSIGNED">A total of 51 cases were enrolled in the study, of which 7 cases were negative while 44 children were positive for viruses. The most common respiratory virus was Rhinovirus in 32 patients (72.2%), then parainfluenza virus (PIV) in 12 (27.3%), of which subtypes PIV1 were 2 (4.5%), PIV3 were 5 (11.4%) and PIV4 were 5 (11.4%) cases. The third common viruses were respiratory syncytial virus (RSV) in 9 (20.5%) cases of which 3 (6.8%) were RSVA and 6 (13.6%) were RSVB and adenovirus in 9 cases (20.5%). Boca virus was found in 8 (18.2%) patients, corona virus 2 (4.5%) patients, H1N1 2 (4.5%) patients, enterovirus 2 patients (4.5%) and human metapneumovirus in one case (2.3%). Influenza B and PIV2 were not detected. Coinfection was found in 28 (63.7%). Mortality occurred in 12 (23.5%). There was no significant relation between virus type or coinfection with disease severity.</AbstractText><AbstractText Label="Conclusions" NlmCategory="UNASSIGNED">RV was the most commonly detected virus in children under 3 years admitted with acute lower respiratory tract infections. Coinfection was present in the majority of our patients; however it was not related significantly to parameters of disease severity.</AbstractText><CopyrightInformation>© 2015 The Authors.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Meligy</LastName><ForeName>Bassant</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Pediatric Department, Faculty of Medicine, Cairo University, Egypt.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sayed</LastName><ForeName>Amal</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Clinical and Chemical Pathology Department, Faculty of Medicine, Cairo University, Egypt.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ismail</LastName><ForeName>Dalia Kadry</ForeName><Initials>DK</Initials><AffiliationInfo><Affiliation>Clinical and Chemical Pathology Department, Faculty of Medicine, Cairo University, Egypt.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kamal</LastName><ForeName>Dina</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Pediatric Department, Faculty of Medicine, Cairo University, Egypt.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Abdel-Latif</LastName><ForeName>Walaa</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Medical Microbiology and Immunology Department, Faculty of Medicine, Ain Shams University, Egypt.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Erfan</LastName><ForeName>Dina M</ForeName><Initials>DM</Initials><AffiliationInfo><Affiliation>Medical Microbiology and Immunology Department, Faculty of Medicine, Ain Shams University, Egypt.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>12</Month><Day>30</Day></ArticleDate></Article><MedlineJournalInfo><Country>Egypt</Country><MedlineTA>Gaz Egypt Paediatr Assoc</MedlineTA><NlmUniqueID>7509401</NlmUniqueID><ISSNLinking>1110-6638</ISSNLinking></MedlineJournalInfo><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">ALRTI, acute lower respiratory tract infection</Keyword><Keyword MajorTopicYN="N">Acute lower respiratory tract infection</Keyword><Keyword MajorTopicYN="N">Ad, adenovirus</Keyword><Keyword MajorTopicYN="N">CMTA, Catcher Melting Temperature Analysis</Keyword><Keyword MajorTopicYN="N">CRP, C reactive protein</Keyword><Keyword MajorTopicYN="N">CRX, chest X ray</Keyword><Keyword MajorTopicYN="N">Infants</Keyword><Keyword MajorTopicYN="N">PCR</Keyword><Keyword MajorTopicYN="N">PIV, parainfluenza virus</Keyword><Keyword MajorTopicYN="N">PaO2, partial pressure of oxygen</Keyword><Keyword MajorTopicYN="N">RSV, respiratory syncytial virus</Keyword><Keyword MajorTopicYN="N">RV, rhinovirus</Keyword><Keyword MajorTopicYN="N">SARS, severe acute respiratory syndrome</Keyword><Keyword MajorTopicYN="N">TLC, total leucocytic count</Keyword><Keyword MajorTopicYN="N">Viral</Keyword><Keyword MajorTopicYN="N">WHO, World Health Organization</Keyword><Keyword MajorTopicYN="N">hMPV, human metapneumovirus</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2015</Year><Month>08</Month><Day>19</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2015</Year><Month>11</Month><Day>28</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>4</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>3</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>3</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32288487</ArticleId><ArticleId IdType="doi">10.1016/j.epag.2015.11.005</ArticleId><ArticleId IdType="pii">S1110-6638(15)00062-2</ArticleId><ArticleId IdType="pmc">PMC7110902</ArticleId></ArticleIdList><pmc-dir>pmcsd</pmc-dir>
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IdType="pubmed">23169964</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>Égypte</li></country></list><tree><country name="Égypte"><noRegion><name sortKey="Meligy, Bassant" sort="Meligy, Bassant" uniqKey="Meligy B" first="Bassant" last="Meligy">Bassant Meligy</name></noRegion><name sortKey="Abdel Latif, Walaa" sort="Abdel Latif, Walaa" uniqKey="Abdel Latif W" first="Walaa" last="Abdel-Latif">Walaa Abdel-Latif</name><name sortKey="Erfan, Dina M" sort="Erfan, Dina M" uniqKey="Erfan D" first="Dina M" last="Erfan">Dina M. Erfan</name><name sortKey="Ismail, Dalia Kadry" sort="Ismail, Dalia Kadry" uniqKey="Ismail D" first="Dalia Kadry" last="Ismail">Dalia Kadry Ismail</name><name sortKey="Kamal, Dina" sort="Kamal, Dina" uniqKey="Kamal D" first="Dina" last="Kamal">Dina Kamal</name><name sortKey="Sayed, Amal" sort="Sayed, Amal" uniqKey="Sayed A" first="Amal" last="Sayed">Amal Sayed</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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