Serveur d'exploration SRAS

Attention, ce site est en cours de développement !
Attention, site généré par des moyens informatiques à partir de corpus bruts.
Les informations ne sont donc pas validées.

Viral lung infections and the potential for a human pandemic

Identifieur interne : 001863 ( Pmc/Curation ); précédent : 001862; suivant : 001864

Viral lung infections and the potential for a human pandemic

Auteurs : Helen Roberts ; Wei Shen Lim

Source :

RBID : PMC:7108287

Abstract

Some newly emerging viral lung infections have the potential to cause large outbreaks of severe respiratory disease amongst humans. In this contribution we discuss infections by influenza A (H5N1), SARS and Hanta virus. The H5N1 subtype of avian influenza (bird flu) has crossed the species barrier and causes severe illness in humans. So far, 328 humans in twelve countries have contracted the disease and 200 have died. The young are particularly affected. Oseltamivir is the antiviral drug of choice and should be given as early as possible. Patients require supportive care, often including invasive ventilation. If H5N1 develops the ability to transmit efficiently between humans, an influenza pandemic is likely. Severe acute respiratory syndrome (SARS) was first seen in China in 2002. The outbreak was finally contained in 2003, by which time 8098 probable SARS cases had been identified with at least 774 deaths. The virus was identified in 2003 as belonging to the coronaviridae family. SARS is transmitted between humans and clusters have been seen. The mainstay of treatment is supportive. Various antiviral agents and adjunctive therapies were tried but none were conclusively effective. Hanta virus is an emerging cause of viral lung disease. In 1993, a new species of Hanta virus was recognized, after an outbreak of a new rapidly progressive pulmonary syndrome in the US, 465 cases of ‘Sin Nombre’ virus have now been seen in the US with a mortality rate of 35%. Many of the confirmed cases had contact with rodents (the major host of hanta viruses). Treatment is supportive, as there is no specific therapy.


Url:
DOI: 10.1016/j.mpmed.2008.03.009
PubMed: NONE
PubMed Central: 7108287

Links toward previous steps (curation, corpus...)


Links to Exploration step

PMC:7108287

Le document en format XML

<record>
<TEI>
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">Viral lung infections and the potential for a human pandemic</title>
<author>
<name sortKey="Roberts, Helen" sort="Roberts, Helen" uniqKey="Roberts H" first="Helen" last="Roberts">Helen Roberts</name>
</author>
<author>
<name sortKey="Lim, Wei Shen" sort="Lim, Wei Shen" uniqKey="Lim W" first="Wei Shen" last="Lim">Wei Shen Lim</name>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">PMC</idno>
<idno type="pmc">7108287</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108287</idno>
<idno type="RBID">PMC:7108287</idno>
<idno type="doi">10.1016/j.mpmed.2008.03.009</idno>
<idno type="pmid">NONE</idno>
<date when="2008">2008</date>
<idno type="wicri:Area/Pmc/Corpus">001863</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001863</idno>
<idno type="wicri:Area/Pmc/Curation">001863</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001863</idno>
</publicationStmt>
<sourceDesc>
<biblStruct>
<analytic>
<title xml:lang="en" level="a" type="main">Viral lung infections and the potential for a human pandemic</title>
<author>
<name sortKey="Roberts, Helen" sort="Roberts, Helen" uniqKey="Roberts H" first="Helen" last="Roberts">Helen Roberts</name>
</author>
<author>
<name sortKey="Lim, Wei Shen" sort="Lim, Wei Shen" uniqKey="Lim W" first="Wei Shen" last="Lim">Wei Shen Lim</name>
</author>
</analytic>
<series>
<title level="j">Medicine (Abingdon, England : UK Ed.)</title>
<idno type="ISSN">1357-3039</idno>
<idno type="eISSN">1878-9390</idno>
<imprint>
<date when="2008">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass></textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<p>Some newly emerging viral lung infections have the potential to cause large outbreaks of severe respiratory disease amongst humans. In this contribution we discuss infections by influenza A (H5N1), SARS and Hanta virus. The H5N1 subtype of avian influenza (bird flu) has crossed the species barrier and causes severe illness in humans. So far, 328 humans in twelve countries have contracted the disease and 200 have died. The young are particularly affected. Oseltamivir is the antiviral drug of choice and should be given as early as possible. Patients require supportive care, often including invasive ventilation. If H5N1 develops the ability to transmit efficiently between humans, an influenza pandemic is likely. Severe acute respiratory syndrome (SARS) was first seen in China in 2002. The outbreak was finally contained in 2003, by which time 8098 probable SARS cases had been identified with at least 774 deaths. The virus was identified in 2003 as belonging to the coronaviridae family. SARS is transmitted between humans and clusters have been seen. The mainstay of treatment is supportive. Various antiviral agents and adjunctive therapies were tried but none were conclusively effective. Hanta virus is an emerging cause of viral lung disease. In 1993, a new species of Hanta virus was recognized, after an outbreak of a new rapidly progressive pulmonary syndrome in the US, 465 cases of ‘Sin Nombre’ virus have now been seen in the US with a mortality rate of 35%. Many of the confirmed cases had contact with rodents (the major host of hanta viruses). Treatment is supportive, as there is no specific therapy.</p>
</div>
</front>
<back>
<div1 type="bibliography">
<listBibl>
<biblStruct>
<analytic>
<author>
<name sortKey="Department For Environment Food And Rural Affairs" uniqKey="Department For Environment Food And Rural Affairs">Department for Environment, Food and Rural Affairs</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="World Health Organization" uniqKey="World Health Organization">World Health Organization</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Department Of Health" uniqKey="Department Of Health">Department of health</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="World Health Organization" uniqKey="World Health Organization">World Health Organization</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="World Health Organization" uniqKey="World Health Organization">World Health Organization</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="The Writing Committee Of The World Health Organization Consultation On Human Influenza Ah" uniqKey="The Writing Committee Of The World Health Organization Consultation On Human Influenza Ah">The Writing Committee of the World Health Organization Consultation on Human Influenza AH</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name>
</author>
<author>
<name sortKey="Wong, S S" uniqKey="Wong S">S.S. Wong</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Health Protection Agency" uniqKey="Health Protection Agency">Health Protection Agency</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="World Health Organization" uniqKey="World Health Organization">World Health Organization</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Centre For Disease Control" uniqKey="Centre For Disease Control">Centre for Disease Control</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="World Health Organization" uniqKey="World Health Organization">World Health Organization</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Health Protection Agency" uniqKey="Health Protection Agency">Health Protection Agency</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Kamps, B S" uniqKey="Kamps B">B.S. Kamps</name>
</author>
<author>
<name sortKey="Hoffmann, S" uniqKey="Hoffmann S">S. Hoffmann</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name>
</author>
<author>
<name sortKey="Lai, S T" uniqKey="Lai S">S.T. Lai</name>
</author>
<author>
<name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Ksiazek, T G" uniqKey="Ksiazek T">T.G. Ksiazek</name>
</author>
<author>
<name sortKey="Erdman, D" uniqKey="Erdman D">D. Erdman</name>
</author>
<author>
<name sortKey="Goldsmith, C S" uniqKey="Goldsmith C">C.S. Goldsmith</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name>
</author>
<author>
<name sortKey="Gunther, S" uniqKey="Gunther S">S. Gunther</name>
</author>
<author>
<name sortKey="Preiser, W" uniqKey="Preiser W">W. Preiser</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="World Health Organization" uniqKey="World Health Organization">World Health Organization</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Peiris, J S M" uniqKey="Peiris J">J.S.M. Peiris</name>
</author>
<author>
<name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name>
</author>
<author>
<name sortKey="Osterhaus, A D M E" uniqKey="Osterhaus A">A.D.M.E. Osterhaus</name>
</author>
</analytic>
</biblStruct>
<biblStruct>
<analytic>
<author>
<name sortKey="Centre For Disease Control" uniqKey="Centre For Disease Control">Centre for Disease Control</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<pmc article-type="review-article">
<pmc-dir>properties open_access</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Medicine (Abingdon)</journal-id>
<journal-id journal-id-type="iso-abbrev">Medicine (Abingdon)</journal-id>
<journal-title-group>
<journal-title>Medicine (Abingdon, England : UK Ed.)</journal-title>
</journal-title-group>
<issn pub-type="ppub">1357-3039</issn>
<issn pub-type="epub">1878-9390</issn>
<publisher>
<publisher-name>Elsevier Ltd.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmc">7108287</article-id>
<article-id pub-id-type="publisher-id">S1357-3039(08)00102-3</article-id>
<article-id pub-id-type="doi">10.1016/j.mpmed.2008.03.009</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Viral lung infections and the potential for a human pandemic</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" id="au2">
<name>
<surname>Roberts</surname>
<given-names>Helen</given-names>
</name>
</contrib>
<contrib contrib-type="author" id="au1">
<name>
<surname>Lim</surname>
<given-names>Wei Shen</given-names>
</name>
</contrib>
</contrib-group>
<aff>
<bold>Helen Roberts MRCP</bold>
is a Specialist Registrar in Respiratory Medicine at Kingsmill Hospital, Mansfield, UK. Competing interests: none declared</aff>
<aff>
<bold>Wei Shen Lim DM FRCP</bold>
is Consultant Respiratory Physician, Nottingham University Hospitals, Nottingham, UK. Competing interests: none declared</aff>
<pub-date pub-type="pmc-release">
<day>24</day>
<month>5</month>
<year>2008</year>
</pub-date>
<pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub">
<month>6</month>
<year>2008</year>
</pub-date>
<pub-date pub-type="epub">
<day>24</day>
<month>5</month>
<year>2008</year>
</pub-date>
<volume>36</volume>
<issue>6</issue>
<fpage>291</fpage>
<lpage>294</lpage>
<permissions>
<copyright-statement>Copyright © 2008 Elsevier Ltd. All rights reserved.</copyright-statement>
<copyright-year>2008</copyright-year>
<copyright-holder>Elsevier Ltd</copyright-holder>
<license>
<license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p>
</license>
</permissions>
<abstract>
<p>Some newly emerging viral lung infections have the potential to cause large outbreaks of severe respiratory disease amongst humans. In this contribution we discuss infections by influenza A (H5N1), SARS and Hanta virus. The H5N1 subtype of avian influenza (bird flu) has crossed the species barrier and causes severe illness in humans. So far, 328 humans in twelve countries have contracted the disease and 200 have died. The young are particularly affected. Oseltamivir is the antiviral drug of choice and should be given as early as possible. Patients require supportive care, often including invasive ventilation. If H5N1 develops the ability to transmit efficiently between humans, an influenza pandemic is likely. Severe acute respiratory syndrome (SARS) was first seen in China in 2002. The outbreak was finally contained in 2003, by which time 8098 probable SARS cases had been identified with at least 774 deaths. The virus was identified in 2003 as belonging to the coronaviridae family. SARS is transmitted between humans and clusters have been seen. The mainstay of treatment is supportive. Various antiviral agents and adjunctive therapies were tried but none were conclusively effective. Hanta virus is an emerging cause of viral lung disease. In 1993, a new species of Hanta virus was recognized, after an outbreak of a new rapidly progressive pulmonary syndrome in the US, 465 cases of ‘Sin Nombre’ virus have now been seen in the US with a mortality rate of 35%. Many of the confirmed cases had contact with rodents (the major host of hanta viruses). Treatment is supportive, as there is no specific therapy.</p>
</abstract>
<kwd-group>
<title>Keywords</title>
<kwd>avian influenza</kwd>
<kwd>Hanta virus</kwd>
<kwd>human pandemic</kwd>
<kwd>H5N1</kwd>
<kwd>outbreak</kwd>
<kwd>SARS – CoV</kwd>
<kwd>severe acute respiratory syndrome</kwd>
<kwd>Sin Nombre virus</kwd>
<kwd>viral lung infections</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Pmc/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001863 | SxmlIndent | more

Ou

HfdSelect -h $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd -nk 001863 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    SrasV1
   |flux=    Pmc
   |étape=   Curation
   |type=    RBID
   |clé=     PMC:7108287
   |texte=   Viral lung infections and the potential for a human pandemic
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Curation/RBID.i   -Sk "pubmed:NONE" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd   \
       | NlmPubMed2Wicri -a SrasV1 

Wicri

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 28 14:49:16 2020. Site generation: Sat Mar 27 22:06:49 2021