Extensive diversity of coronaviruses in bats from China
Identifieur interne : 001575 ( Pmc/Curation ); précédent : 001574; suivant : 001576Extensive diversity of coronaviruses in bats from China
Auteurs : Xian-Dan Lin [République populaire de Chine] ; Wen Wang [République populaire de Chine] ; Zong-Yu Hao [République populaire de Chine] ; Zhao-Xiao Wang [République populaire de Chine] ; Wen-Ping Guo [République populaire de Chine] ; Xiao-Qing Guan [République populaire de Chine] ; Miao-Ruo Wang [République populaire de Chine] ; Hong-Wei Wang [République populaire de Chine] ; Run-Hong Zhou [République populaire de Chine] ; Ming-Hui Li [République populaire de Chine] ; Guang-Peng Tang [République populaire de Chine] ; Jun Wu [République populaire de Chine] ; Edward C. Holmes [Australie] ; Yong-Zhen Zhang [République populaire de Chine]Source :
- Virology [ 0042-6822 ] ; 2017.
Abstract
To help reveal the diversity and evolution of bat coronaviruses we collected 1067 bats from 21 species in China. A total of 73 coronaviruses (32 alphacoronaviruses and 41 betacoronaviruses) were identified in these bats, with an overall prevalence of 6.84%. All newly-identified betacoronaviruses were SARS-related Rhinolophus bat coronaviruses (SARSr-Rh-BatCoV). Importantly, with the exception of the S gene, the genome sequences of the SARSr-Rh-BatCoVs sampled in Guizhou province were closely related to SARS-related human coronavirus. Additionally, the newly-identified alphacoronaviruses exhibited high genetic diversity and some may represent novel species. Our phylogenetic analyses also provided insights into the transmission of these viruses among bat species, revealing a general clustering by geographic location rather than by bat species. Inter-species transmission among bats from the same genus was also commonplace in both the alphacoronaviruses and betacoronaviruses. Overall, these data suggest that high contact rates among specific bat species enable the acquisition and spread of coronaviruses.
Url:
DOI: 10.1016/j.virol.2017.03.019
PubMed: 28384506
PubMed Central: 7111643
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for Disease Control and Prevention, Neixiang, Henan Province</wicri:regionArea></affiliation></author><author><name sortKey="Zhou, Run Hong" sort="Zhou, Run Hong" uniqKey="Zhou R" first="Run-Hong" last="Zhou">Run-Hong Zhou</name><affiliation wicri:level="1"><nlm:aff id="aff0005">State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Li, Ming Hui" sort="Li, Ming Hui" uniqKey="Li M" first="Ming-Hui" last="Li">Ming-Hui Li</name><affiliation wicri:level="1"><nlm:aff id="aff0005">State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing</wicri:regionArea></affiliation></author><author><name 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and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">28384506</idno><idno type="pmc">7111643</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111643</idno><idno type="RBID">PMC:7111643</idno><idno type="doi">10.1016/j.virol.2017.03.019</idno><date when="2017">2017</date><idno type="wicri:Area/Pmc/Corpus">001575</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" 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Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff0010">Wenzhou Center for Disease Control and Prevention, Wenzhou, Zhejiang Province, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Wenzhou Center for Disease Control and Prevention, Wenzhou, Zhejiang Province</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Wen" sort="Wang, Wen" uniqKey="Wang W" first="Wen" last="Wang">Wen Wang</name><affiliation wicri:level="1"><nlm:aff id="aff0005">State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Hao, Zong Yu" sort="Hao, Zong Yu" uniqKey="Hao Z" first="Zong-Yu" last="Hao">Zong-Yu Hao</name><affiliation wicri:level="1"><nlm:aff id="aff0015">Henan Center for Disease Control and Prevention, Zhengzhou, Henan Province, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Henan Center for Disease Control and Prevention, Zhengzhou, Henan Province</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Zhao Xiao" sort="Wang, Zhao Xiao" uniqKey="Wang Z" first="Zhao-Xiao" last="Wang">Zhao-Xiao Wang</name><affiliation wicri:level="1"><nlm:aff id="aff0020">Guizhou Center for Disease Control and Prevention, Guiyang, Guizhou Province, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Guizhou Center for Disease Control and Prevention, Guiyang, Guizhou Province</wicri:regionArea></affiliation></author><author><name sortKey="Guo, Wen Ping" sort="Guo, Wen Ping" uniqKey="Guo W" first="Wen-Ping" last="Guo">Wen-Ping Guo</name><affiliation wicri:level="1"><nlm:aff id="aff0005">State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Guan, Xiao Qing" sort="Guan, Xiao Qing" uniqKey="Guan X" first="Xiao-Qing" last="Guan">Xiao-Qing Guan</name><affiliation wicri:level="1"><nlm:aff id="aff0005">State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Miao Ruo" sort="Wang, Miao Ruo" uniqKey="Wang M" first="Miao-Ruo" last="Wang">Miao-Ruo Wang</name><affiliation wicri:level="1"><nlm:aff id="aff0025">Longquan Center for Disease Control and Prevention, Longquan, Zhejiang Province, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Longquan Center for Disease Control and Prevention, Longquan, Zhejiang Province</wicri:regionArea></affiliation></author><author><name sortKey="Wang, Hong Wei" sort="Wang, Hong Wei" uniqKey="Wang H" first="Hong-Wei" last="Wang">Hong-Wei Wang</name><affiliation wicri:level="1"><nlm:aff id="aff0030">Neixiang Center for Disease Control and Prevention, Neixiang, Henan Province, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Neixiang Center for Disease Control and Prevention, Neixiang, Henan Province</wicri:regionArea></affiliation></author><author><name sortKey="Zhou, Run Hong" sort="Zhou, Run Hong" uniqKey="Zhou R" first="Run-Hong" last="Zhou">Run-Hong Zhou</name><affiliation wicri:level="1"><nlm:aff id="aff0005">State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Li, Ming Hui" sort="Li, Ming Hui" uniqKey="Li M" first="Ming-Hui" last="Li">Ming-Hui Li</name><affiliation wicri:level="1"><nlm:aff id="aff0005">State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing</wicri:regionArea></affiliation></author><author><name sortKey="Tang, Guang Peng" sort="Tang, Guang Peng" uniqKey="Tang G" first="Guang-Peng" last="Tang">Guang-Peng Tang</name><affiliation wicri:level="1"><nlm:aff id="aff0020">Guizhou Center for Disease Control and Prevention, Guiyang, Guizhou Province, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Guizhou Center for Disease Control and Prevention, Guiyang, Guizhou Province</wicri:regionArea></affiliation></author><author><name sortKey="Wu, Jun" sort="Wu, Jun" uniqKey="Wu J" first="Jun" last="Wu">Jun Wu</name><affiliation wicri:level="1"><nlm:aff id="aff0035">Jiyuan Center for Disease Control and Prevention, Jiyuan, Henan Province, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Jiyuan Center for Disease Control and Prevention, Jiyuan, Henan Province</wicri:regionArea></affiliation></author><author><name sortKey="Holmes, Edward C" sort="Holmes, Edward C" uniqKey="Holmes E" first="Edward C." last="Holmes">Edward C. Holmes</name><affiliation wicri:level="1"><nlm:aff id="aff0040">Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, School of Life and Environmental Sciences and Sydney Medical School, The University of Sydney, Sydney, NSW 2006, Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, School of Life and Environmental Sciences and Sydney Medical School, The University of Sydney, Sydney, NSW 2006</wicri:regionArea></affiliation></author><author><name sortKey="Zhang, Yong Zhen" sort="Zhang, Yong Zhen" uniqKey="Zhang Y" first="Yong-Zhen" last="Zhang">Yong-Zhen Zhang</name><affiliation wicri:level="1"><nlm:aff id="aff0005">State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing</wicri:regionArea></affiliation></author></analytic><series><title level="j">Virology</title><idno type="ISSN">0042-6822</idno><idno type="eISSN">1096-0341</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>To help reveal the diversity and evolution of bat coronaviruses we collected 1067 bats from 21 species in China. A total of 73 coronaviruses (32 alphacoronaviruses and 41 betacoronaviruses) were identified in these bats, with an overall prevalence of 6.84%. All newly-identified betacoronaviruses were SARS-related Rhinolophus bat coronaviruses (SARSr-Rh-BatCoV). Importantly, with the exception of the S gene, the genome sequences of the SARSr-Rh-BatCoVs sampled in Guizhou province were closely related to SARS-related human coronavirus. Additionally, the newly-identified alphacoronaviruses exhibited high genetic diversity and some may represent novel species. Our phylogenetic analyses also provided insights into the transmission of these viruses among bat species, revealing a general clustering by geographic location rather than by bat species. Inter-species transmission among bats from the same genus was also commonplace in both the alphacoronaviruses and betacoronaviruses. Overall, these data suggest that high contact rates among specific bat species enable the acquisition and spread of coronaviruses.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Annan, A" uniqKey="Annan A">A. Annan</name></author><author><name sortKey="Baldwin, H J" uniqKey="Baldwin H">H.J. Baldwin</name></author><author><name sortKey="Corman, V M" uniqKey="Corman V">V.M. Corman</name></author><author><name sortKey="Klose, S M" uniqKey="Klose S">S.M. Klose</name></author><author><name sortKey="Owusu, M" uniqKey="Owusu M">M. Owusu</name></author><author><name sortKey="Nkrumah, E E" uniqKey="Nkrumah E">E.E. Nkrumah</name></author><author><name sortKey="Badu, E K" uniqKey="Badu E">E.K. Badu</name></author><author><name sortKey="Anti, P" uniqKey="Anti P">P. Anti</name></author><author><name sortKey="Agbenyega, O" uniqKey="Agbenyega O">O. Agbenyega</name></author><author><name sortKey="Meyer, B" uniqKey="Meyer B">B. Meyer</name></author><author><name sortKey="Oppong, S" uniqKey="Oppong S">S. Oppong</name></author><author><name sortKey="Sarkodie, Y A" uniqKey="Sarkodie Y">Y.A. Sarkodie</name></author><author><name sortKey="Kalko, E K" uniqKey="Kalko E">E.K. Kalko</name></author><author><name sortKey="Lina, P H" uniqKey="Lina P">P.H. Lina</name></author><author><name sortKey="Godlevska, E V" uniqKey="Godlevska E">E.V. Godlevska</name></author><author><name sortKey="Reusken, C" uniqKey="Reusken C">C. Reusken</name></author><author><name sortKey="Seebens, A" uniqKey="Seebens A">A. Seebens</name></author><author><name sortKey="Gloza Rausch, F" uniqKey="Gloza Rausch F">F. Gloza-Rausch</name></author><author><name sortKey="Vallo, P" uniqKey="Vallo P">P. Vallo</name></author><author><name sortKey="Tschapka, M" uniqKey="Tschapka M">M. Tschapka</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author><author><name sortKey="Drexler, J F" uniqKey="Drexler J">J.F. Drexler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Balboni, A" uniqKey="Balboni A">A. Balboni</name></author><author><name sortKey="Battilani, M" uniqKey="Battilani M">M. Battilani</name></author><author><name sortKey="Prosperi, S" uniqKey="Prosperi S">S. Prosperi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bermingham, A" uniqKey="Bermingham A">A. Bermingham</name></author><author><name sortKey="Chand, M A" uniqKey="Chand M">M.A. Chand</name></author><author><name sortKey="Brown, C S" uniqKey="Brown C">C.S. Brown</name></author><author><name sortKey="Aarons, E" uniqKey="Aarons E">E. Aarons</name></author><author><name sortKey="Tong, C" uniqKey="Tong C">C. Tong</name></author><author><name sortKey="Langrish, C" uniqKey="Langrish C">C. Langrish</name></author><author><name sortKey="Hoschler, K" uniqKey="Hoschler K">K. Hoschler</name></author><author><name sortKey="Brown, K" uniqKey="Brown K">K. Brown</name></author><author><name sortKey="Galiano, M" uniqKey="Galiano M">M. Galiano</name></author><author><name sortKey="Myers, R" uniqKey="Myers R">R. Myers</name></author><author><name sortKey="Pebody, R G" uniqKey="Pebody R">R.G. Pebody</name></author><author><name sortKey="Green, H K" uniqKey="Green H">H.K. Green</name></author><author><name sortKey="Boddington, N L" uniqKey="Boddington N">N.L. Boddington</name></author><author><name sortKey="Gopal, R" uniqKey="Gopal R">R. Gopal</name></author><author><name sortKey="Price, N" uniqKey="Price N">N. Price</name></author><author><name sortKey="Newsholme, W" uniqKey="Newsholme W">W. Newsholme</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author><author><name sortKey="Fouchier, R A" uniqKey="Fouchier R">R.A. Fouchier</name></author><author><name sortKey="Zambon, M" uniqKey="Zambon M">M. Zambon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chu, D K" uniqKey="Chu D">D.K. Chu</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Chen, H" uniqKey="Chen H">H. Chen</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Conow, C" uniqKey="Conow C">C. Conow</name></author><author><name sortKey="Fielder, D" uniqKey="Fielder D">D. Fielder</name></author><author><name sortKey="Ovadia, Y" uniqKey="Ovadia Y">Y. Ovadia</name></author><author><name sortKey="Libeskind Hadas, R" uniqKey="Libeskind Hadas R">R. Libeskind-Hadas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Corman, V M" uniqKey="Corman V">V.M. Corman</name></author><author><name sortKey="Ithete, N L" uniqKey="Ithete N">N.L. Ithete</name></author><author><name sortKey="Richards, L R" uniqKey="Richards L">L.R. Richards</name></author><author><name sortKey="Schoeman, M C" uniqKey="Schoeman M">M.C. Schoeman</name></author><author><name sortKey="Preiser, W" uniqKey="Preiser W">W. Preiser</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author><author><name sortKey="Drexler, J F" uniqKey="Drexler J">J.F. Drexler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Corman, V M" uniqKey="Corman V">V.M. Corman</name></author><author><name sortKey="Baldwin, H J" uniqKey="Baldwin H">H.J. Baldwin</name></author><author><name sortKey="Tateno, A F" uniqKey="Tateno A">A.F. Tateno</name></author><author><name sortKey="Zerbinati, R M" uniqKey="Zerbinati R">R.M. Zerbinati</name></author><author><name sortKey="Annan, A" uniqKey="Annan A">A. Annan</name></author><author><name sortKey="Owusu, M" uniqKey="Owusu M">M. Owusu</name></author><author><name sortKey="Nkrumah, E E" uniqKey="Nkrumah E">E.E. Nkrumah</name></author><author><name sortKey="Maganga, G D" uniqKey="Maganga G">G.D. Maganga</name></author><author><name sortKey="Oppong, S" uniqKey="Oppong S">S. Oppong</name></author><author><name sortKey="Adu Sarkodie, Y" uniqKey="Adu Sarkodie Y">Y. Adu-Sarkodie</name></author><author><name sortKey="Vallo, P" uniqKey="Vallo P">P. Vallo</name></author><author><name sortKey="Da Silva Filho, L V" uniqKey="Da Silva Filho L">L.V. da Silva Filho</name></author><author><name sortKey="Leroy, E M" uniqKey="Leroy E">E.M. Leroy</name></author><author><name sortKey="Thiel, V" uniqKey="Thiel V">V. Thiel</name></author><author><name sortKey="Van Der Hoek, L" uniqKey="Van Der Hoek L">L. van der Hoek</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author><author><name sortKey="Tschapka, M" uniqKey="Tschapka M">M. Tschapka</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author><author><name sortKey="Drexler, J F" uniqKey="Drexler J">J.F. Drexler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Corman, V M" uniqKey="Corman V">V.M. Corman</name></author><author><name sortKey="Rasche, A" uniqKey="Rasche A">A. Rasche</name></author><author><name sortKey="Diallo, T D" uniqKey="Diallo T">T.D. Diallo</name></author><author><name sortKey="Cottontail, V M" uniqKey="Cottontail V">V.M. Cottontail</name></author><author><name sortKey="Stocker, A" uniqKey="Stocker A">A. Stöcker</name></author><author><name sortKey="Souza, B F" uniqKey="Souza B">B.F. Souza</name></author><author><name sortKey="Correa, J I" uniqKey="Correa J">J.I. Corrêa</name></author><author><name sortKey="Carneiro, A J" uniqKey="Carneiro A">A.J. Carneiro</name></author><author><name sortKey="Franke, C R" uniqKey="Franke C">C.R. Franke</name></author><author><name sortKey="Nagy, M" uniqKey="Nagy M">M. Nagy</name></author><author><name sortKey="Metz, M" uniqKey="Metz M">M. Metz</name></author><author><name sortKey="Knornschild, M" uniqKey="Knornschild M">M. Knörnschild</name></author><author><name sortKey="Kalko, E K" uniqKey="Kalko E">E.K. Kalko</name></author><author><name sortKey="Ghanem, S J" uniqKey="Ghanem S">S.J. Ghanem</name></author><author><name sortKey="Morales, K D" uniqKey="Morales K">K.D. Morales</name></author><author><name sortKey="Salsamendi, E" uniqKey="Salsamendi E">E. Salsamendi</name></author><author><name sortKey="Spinola, M" uniqKey="Spinola M">M. Spínola</name></author><author><name sortKey="Herrler, G" uniqKey="Herrler G">G. Herrler</name></author><author><name sortKey="Voigt, C C" uniqKey="Voigt C">C.C. Voigt</name></author><author><name sortKey="Tschapka, M" uniqKey="Tschapka M">M. Tschapka</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author><author><name sortKey="Drexler, J F" uniqKey="Drexler J">J.F. Drexler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cui, J" uniqKey="Cui J">J. Cui</name></author><author><name sortKey="Han, N" uniqKey="Han N">N. Han</name></author><author><name sortKey="Streicker, D" uniqKey="Streicker D">D. Streicker</name></author><author><name sortKey="Li, G" uniqKey="Li G">G. Li</name></author><author><name sortKey="Tang, X" uniqKey="Tang X">X. Tang</name></author><author><name sortKey="Shi, Z" uniqKey="Shi Z">Z. Shi</name></author><author><name sortKey="Hu, Z" uniqKey="Hu Z">Z. Hu</name></author><author><name sortKey="Zhao, G" uniqKey="Zhao G">G. Zhao</name></author><author><name sortKey="Fontanet, A" uniqKey="Fontanet A">A. Fontanet</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Wang, L" uniqKey="Wang L">L. Wang</name></author><author><name sortKey="Jones, G" uniqKey="Jones G">G. Jones</name></author><author><name sortKey="Field, H E" uniqKey="Field H">H.E. Field</name></author><author><name sortKey="Daszak, P" uniqKey="Daszak P">P. Daszak</name></author><author><name sortKey="Zhang, S" uniqKey="Zhang S">S. Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Drexler, J F" uniqKey="Drexler J">J.F. Drexler</name></author><author><name sortKey="Corman, V M" uniqKey="Corman V">V.M. Corman</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Drexler, J F" uniqKey="Drexler J">J.F. Drexler</name></author><author><name sortKey="Gloza Rausch, F" uniqKey="Gloza Rausch F">F. Gloza-Rausch</name></author><author><name sortKey="Glende, J" uniqKey="Glende J">J. Glende</name></author><author><name sortKey="Corman, V M" uniqKey="Corman V">V.M. Corman</name></author><author><name sortKey="Muth, D" uniqKey="Muth D">D. Muth</name></author><author><name sortKey="Goettsche, M" uniqKey="Goettsche M">M. Goettsche</name></author><author><name sortKey="Seebens, A" uniqKey="Seebens A">A. Seebens</name></author><author><name sortKey="Niedrig, M" uniqKey="Niedrig M">M. Niedrig</name></author><author><name sortKey="Pfefferle, S" uniqKey="Pfefferle S">S. Pfefferle</name></author><author><name sortKey="Yordanov, S" uniqKey="Yordanov S">S. Yordanov</name></author><author><name sortKey="Zhelyazkov, L" uniqKey="Zhelyazkov L">L. Zhelyazkov</name></author><author><name sortKey="Hermanns, U" uniqKey="Hermanns U">U. Hermanns</name></author><author><name sortKey="Vallo, P" uniqKey="Vallo P">P. Vallo</name></author><author><name sortKey="Lukashev, A" uniqKey="Lukashev A">A. Lukashev</name></author><author><name sortKey="Muller, M A" uniqKey="Muller M">M.A. Muller</name></author><author><name sortKey="Deng, H" uniqKey="Deng H">H. Deng</name></author><author><name sortKey="Herrler, G" uniqKey="Herrler G">G. Herrler</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ge, X Y" uniqKey="Ge X">X.Y. Ge</name></author><author><name sortKey="Li, J L" uniqKey="Li J">J.L. Li</name></author><author><name sortKey="Yang, X L" uniqKey="Yang X">X.L. Yang</name></author><author><name sortKey="Chmura, A A" uniqKey="Chmura A">A.A. Chmura</name></author><author><name sortKey="Zhu, G" uniqKey="Zhu G">G. Zhu</name></author><author><name sortKey="Epstein, J H" uniqKey="Epstein J">J.H. Epstein</name></author><author><name sortKey="Mazet, J K" uniqKey="Mazet J">J.K. Mazet</name></author><author><name sortKey="Hu, B" uniqKey="Hu B">B. Hu</name></author><author><name sortKey="Zhang, W" uniqKey="Zhang W">W. Zhang</name></author><author><name sortKey="Peng, C" uniqKey="Peng C">C. Peng</name></author><author><name sortKey="Zhang, Y J" uniqKey="Zhang Y">Y.J. Zhang</name></author><author><name sortKey="Luo, C M" uniqKey="Luo C">C.M. Luo</name></author><author><name sortKey="Tan, B" uniqKey="Tan B">B. Tan</name></author><author><name sortKey="Wang, N" uniqKey="Wang N">N. Wang</name></author><author><name sortKey="Zhu, Y" uniqKey="Zhu Y">Y. Zhu</name></author><author><name sortKey="Crameri, G" uniqKey="Crameri G">G. Crameri</name></author><author><name sortKey="Zhang, S Y" uniqKey="Zhang S">S.Y. Zhang</name></author><author><name sortKey="Wang, L F" uniqKey="Wang L">L.F. Wang</name></author><author><name sortKey="Daszak, P" uniqKey="Daszak P">P. Daszak</name></author><author><name sortKey="Shi, Z L" uniqKey="Shi Z">Z.L. Shi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Groot, R J" uniqKey="De Groot R">R.J. de Groot</name></author><author><name sortKey="Baker, S C" uniqKey="Baker S">S.C. Baker</name></author><author><name sortKey="Baric, R" uniqKey="Baric R">R. Baric</name></author><author><name sortKey="Enjuanes, L" uniqKey="Enjuanes L">L. Enjuanes</name></author><author><name sortKey="Gorbalenya, A E" uniqKey="Gorbalenya A">A.E. Gorbalenya</name></author><author><name sortKey="Holmes, K V" uniqKey="Holmes K">K.V. Holmes</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name></author><author><name sortKey="Poon, L" uniqKey="Poon L">L. Poon</name></author><author><name sortKey="Rottier, P J M" uniqKey="Rottier P">P.J.M. Rottier</name></author><author><name sortKey="Talbot, P J" uniqKey="Talbot P">P.J. Talbot</name></author><author><name sortKey="Woo, P C Y" uniqKey="Woo P">P.C.Y. Woo</name></author><author><name sortKey="Ziebuhr, J" uniqKey="Ziebuhr J">J. Ziebuhr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Zheng, B J" uniqKey="Zheng B">B.J. Zheng</name></author><author><name sortKey="He, Y Q" uniqKey="He Y">Y.Q. He</name></author><author><name sortKey="Liu, X L" uniqKey="Liu X">X.L. Liu</name></author><author><name sortKey="Zhuang, Z X" uniqKey="Zhuang Z">Z.X. Zhuang</name></author><author><name sortKey="Cheung, C L" uniqKey="Cheung C">C.L. Cheung</name></author><author><name sortKey="Luo, S W" uniqKey="Luo S">S.W. Luo</name></author><author><name sortKey="Li, P H" uniqKey="Li P">P.H. Li</name></author><author><name sortKey="Zhang, L J" uniqKey="Zhang L">L.J. Zhang</name></author><author><name sortKey="Guan, Y J" uniqKey="Guan Y">Y.J. Guan</name></author><author><name sortKey="Butt, K M" uniqKey="Butt K">K.M. Butt</name></author><author><name sortKey="Wong, K L" uniqKey="Wong K">K.L. Wong</name></author><author><name sortKey="Chan, K W" uniqKey="Chan K">K.W. Chan</name></author><author><name sortKey="Lim, W" uniqKey="Lim W">W. Lim</name></author><author><name sortKey="Shortridge, K F" uniqKey="Shortridge K">K.F. Shortridge</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guindon, S" uniqKey="Guindon S">S. Guindon</name></author><author><name sortKey="Dufayard, J F" uniqKey="Dufayard J">J.F. Dufayard</name></author><author><name sortKey="Lefort, V" uniqKey="Lefort V">V. Lefort</name></author><author><name sortKey="Anisimova, M" uniqKey="Anisimova M">M. Anisimova</name></author><author><name sortKey="Hordijk, W" uniqKey="Hordijk W">W. Hordijk</name></author><author><name sortKey="Gascuel, O" uniqKey="Gascuel O">O. Gascuel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guo, W P" uniqKey="Guo W">W.P. Guo</name></author><author><name sortKey="Lin, X D" uniqKey="Lin X">X.D. Lin</name></author><author><name sortKey="Wang, W" uniqKey="Wang W">W. Wang</name></author><author><name sortKey="Tian, J H" uniqKey="Tian J">J.H. Tian</name></author><author><name sortKey="Cong, M L" uniqKey="Cong M">M.L. Cong</name></author><author><name sortKey="Zhang, H L" uniqKey="Zhang H">H.L. Zhang</name></author><author><name sortKey="Wang, M R" uniqKey="Wang M">M.R. Wang</name></author><author><name sortKey="Zhou, R H" uniqKey="Zhou R">R.H. Zhou</name></author><author><name sortKey="Wang, J B" uniqKey="Wang J">J.B. Wang</name></author><author><name sortKey="Li, M H" uniqKey="Li M">M.H. Li</name></author><author><name sortKey="Xu, J" uniqKey="Xu J">J. Xu</name></author><author><name sortKey="Holmes, E C" uniqKey="Holmes E">E.C. Holmes</name></author><author><name sortKey="Zhang, Y Z" uniqKey="Zhang Y">Y.Z. Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="He, B" uniqKey="He B">B. He</name></author><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y. Zhang</name></author><author><name sortKey="Xu, L" uniqKey="Xu L">L. Xu</name></author><author><name sortKey="Yang, W" uniqKey="Yang W">W. Yang</name></author><author><name sortKey="Yang, F" uniqKey="Yang F">F. Yang</name></author><author><name sortKey="Feng, Y" uniqKey="Feng Y">Y. Feng</name></author><author><name sortKey="Xia, L" uniqKey="Xia L">L. Xia</name></author><author><name sortKey="Zhou, J" uniqKey="Zhou J">J. Zhou</name></author><author><name sortKey="Zhen, W" uniqKey="Zhen W">W. Zhen</name></author><author><name sortKey="Feng, Y" uniqKey="Feng Y">Y. Feng</name></author><author><name sortKey="Guo, H" uniqKey="Guo H">H. Guo</name></author><author><name sortKey="Zhang, H" uniqKey="Zhang H">H. Zhang</name></author><author><name sortKey="Tu, C" uniqKey="Tu C">C. Tu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Der Hoek, L" uniqKey="Van Der Hoek L">L. van der Hoek</name></author><author><name sortKey="Pyrc, K" uniqKey="Pyrc K">K. Pyrc</name></author><author><name sortKey="Jebbink, M F" uniqKey="Jebbink M">M.F. Jebbink</name></author><author><name sortKey="Vermeulen Oost, W" uniqKey="Vermeulen Oost W">W. Vermeulen-Oost</name></author><author><name sortKey="Berkhout, R J" uniqKey="Berkhout R">R.J. Berkhout</name></author><author><name sortKey="Wolthers, K C" uniqKey="Wolthers K">K.C. Wolthers</name></author><author><name sortKey="Wertheim Van" uniqKey="Wertheim Van">Wertheim-van</name></author><author><name sortKey="Dillen, P M" uniqKey="Dillen P">P.,M. Dillen</name></author><author><name sortKey="Kaandorp, J" uniqKey="Kaandorp J">J. Kaandorp</name></author><author><name sortKey="Spaargaren, J" uniqKey="Spaargaren J">J. Spaargaren</name></author><author><name sortKey="Berkhout, B" uniqKey="Berkhout B">B. Berkhout</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hu, B" uniqKey="Hu B">B. Hu</name></author><author><name sortKey="Ge, X" uniqKey="Ge X">X. Ge</name></author><author><name sortKey="Wang, L F" uniqKey="Wang L">L.F. Wang</name></author><author><name sortKey="Shi, Z" uniqKey="Shi Z">Z. Shi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, C" uniqKey="Huang C">C. Huang</name></author><author><name sortKey="Liu, W J" uniqKey="Liu W">W.J. Liu</name></author><author><name sortKey="Xu, W" uniqKey="Xu W">W. Xu</name></author><author><name sortKey="Jin, T" uniqKey="Jin T">T. Jin</name></author><author><name sortKey="Zhao, Y" uniqKey="Zhao Y">Y. Zhao</name></author><author><name sortKey="Song, J" uniqKey="Song J">J. Song</name></author><author><name sortKey="Shi, Y" uniqKey="Shi Y">Y. Shi</name></author><author><name sortKey="Ji, W" uniqKey="Ji W">W. Ji</name></author><author><name sortKey="Jia, H" uniqKey="Jia H">H. Jia</name></author><author><name sortKey="Zhou, Y" uniqKey="Zhou Y">Y. Zhou</name></author><author><name sortKey="Wen, H" uniqKey="Wen H">H. Wen</name></author><author><name sortKey="Zhao, H" uniqKey="Zhao H">H. Zhao</name></author><author><name sortKey="Liu, H" uniqKey="Liu H">H. Liu</name></author><author><name sortKey="Li, H" uniqKey="Li H">H. Li</name></author><author><name sortKey="Wang, Q" uniqKey="Wang Q">Q. Wang</name></author><author><name sortKey="Wu, Y" uniqKey="Wu Y">Y. Wu</name></author><author><name sortKey="Wang, L" uniqKey="Wang L">L. Wang</name></author><author><name sortKey="Liu, D" uniqKey="Liu D">D. Liu</name></author><author><name sortKey="Liu, G" uniqKey="Liu G">G. Liu</name></author><author><name sortKey="Yu, H" uniqKey="Yu H">H. Yu</name></author><author><name sortKey="Holmes, E C" uniqKey="Holmes E">E.C. Holmes</name></author><author><name sortKey="Lu, L" uniqKey="Lu L">L. Lu</name></author><author><name sortKey="Gao, G F" uniqKey="Gao G">G.F. Gao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, Y W" uniqKey="Huang Y">Y.W. Huang</name></author><author><name sortKey="Dickerman, A W" uniqKey="Dickerman A">A.W. Dickerman</name></author><author><name sortKey="Pi Eyro, P" uniqKey="Pi Eyro P">P. Piñeyro</name></author><author><name sortKey="Li, L" uniqKey="Li L">L. Li</name></author><author><name sortKey="Fang, L" uniqKey="Fang L">L. Fang</name></author><author><name sortKey="Kiehne, R" uniqKey="Kiehne R">R. Kiehne</name></author><author><name sortKey="Opriessnig, T" uniqKey="Opriessnig T">T. Opriessnig</name></author><author><name sortKey="Meng, X J" uniqKey="Meng X">X.J. Meng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huynh, J" uniqKey="Huynh J">J. Huynh</name></author><author><name sortKey="Li, S" uniqKey="Li S">S. Li</name></author><author><name sortKey="Yount, B" uniqKey="Yount B">B. Yount</name></author><author><name sortKey="Smith, A" uniqKey="Smith A">A. Smith</name></author><author><name sortKey="Sturges, L" uniqKey="Sturges L">L. Sturges</name></author><author><name sortKey="Olsen, J C" uniqKey="Olsen J">J.C. Olsen</name></author><author><name sortKey="Nagel, J" uniqKey="Nagel J">J. Nagel</name></author><author><name sortKey="Johnson, J B" uniqKey="Johnson J">J.B. Johnson</name></author><author><name sortKey="Agnihothram, S" uniqKey="Agnihothram S">S. Agnihothram</name></author><author><name sortKey="Gates, J E" uniqKey="Gates J">J.E. Gates</name></author><author><name sortKey="Frieman, M B" uniqKey="Frieman M">M.B. Frieman</name></author><author><name sortKey="Baric, R S" uniqKey="Baric R">R.S. Baric</name></author><author><name sortKey="Donaldson, E F" uniqKey="Donaldson E">E.F. Donaldson</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Ithete, N L" uniqKey="Ithete N">N.L. Ithete</name></author><author><name sortKey="Stoffberg, S" uniqKey="Stoffberg S">S. Stoffberg</name></author><author><name sortKey="Corman, V M" uniqKey="Corman V">V.M. Corman</name></author><author><name sortKey="Cottontail, V M" uniqKey="Cottontail V">V.M. Cottontail</name></author><author><name sortKey="Richards, L R" uniqKey="Richards L">L.R. Richards</name></author><author><name sortKey="Schoeman, M C" uniqKey="Schoeman M">M.C. Schoeman</name></author><author><name sortKey="Drosten, C" uniqKey="Drosten C">C. Drosten</name></author><author><name sortKey="Drexler, J F" uniqKey="Drexler J">J.F. Drexler</name></author><author><name sortKey="Preiser, W" uniqKey="Preiser W">W. Preiser</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Katoh, K" uniqKey="Katoh K">K. Katoh</name></author><author><name sortKey="Standley, D M" uniqKey="Standley D">D.M. Standley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ksiazek, T G" uniqKey="Ksiazek T">T.G. Ksiazek</name></author><author><name sortKey="Erdman, D" uniqKey="Erdman D">D. Erdman</name></author><author><name sortKey="Goldsmith, C S" uniqKey="Goldsmith C">C.S. Goldsmith</name></author><author><name sortKey="Zaki, S R" uniqKey="Zaki S">S.R. Zaki</name></author><author><name sortKey="Peret, T" uniqKey="Peret T">T. Peret</name></author><author><name sortKey="Emery, S" uniqKey="Emery S">S. Emery</name></author><author><name sortKey="Tong, S" uniqKey="Tong S">S. Tong</name></author><author><name sortKey="Urbani, C" uniqKey="Urbani C">C. Urbani</name></author><author><name sortKey="Comer, J A" uniqKey="Comer J">J.A. Comer</name></author><author><name sortKey="Lim, W" uniqKey="Lim W">W. Lim</name></author><author><name sortKey="Rollin, P E" uniqKey="Rollin P">P.E. Rollin</name></author><author><name sortKey="Dowell, S F" uniqKey="Dowell S">S.F. Dowell</name></author><author><name sortKey="Ling, A E" uniqKey="Ling A">A.E. Ling</name></author><author><name sortKey="Humphrey, C D" uniqKey="Humphrey C">C.D. Humphrey</name></author><author><name sortKey="Shieh, W J" uniqKey="Shieh W">W.J. Shieh</name></author><author><name sortKey="Guarner, J" uniqKey="Guarner J">J. Guarner</name></author><author><name sortKey="Paddock, C D" uniqKey="Paddock C">C.D. Paddock</name></author><author><name sortKey="Rota, P" uniqKey="Rota P">P. Rota</name></author><author><name sortKey="Fields, B" uniqKey="Fields B">B. Fields</name></author><author><name sortKey="Derisi, J" uniqKey="Derisi J">J. DeRisi</name></author><author><name sortKey="Yang, J Y" uniqKey="Yang J">J.Y. Yang</name></author><author><name sortKey="Cox, N" uniqKey="Cox N">N. Cox</name></author><author><name sortKey="Hughes, J M" uniqKey="Hughes J">J.M. Hughes</name></author><author><name sortKey="Leduc, J W" uniqKey="Leduc J">J.W. LeDuc</name></author><author><name sortKey="Bellini, W J" uniqKey="Bellini W">W.J. Bellini</name></author><author><name sortKey="Anderson, L J" uniqKey="Anderson L">L.J. Anderson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Li, K S" uniqKey="Li K">K.S. Li</name></author><author><name sortKey="Tsang, A K" uniqKey="Tsang A">A.K. Tsang</name></author><author><name sortKey="Lam, C S" uniqKey="Lam C">C.S. Lam</name></author><author><name sortKey="Ahmed, S" uniqKey="Ahmed S">S. Ahmed</name></author><author><name sortKey="Chen, H" uniqKey="Chen H">H. Chen</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Li, K S" uniqKey="Li K">K.S. Li</name></author><author><name sortKey="Huang, Y" uniqKey="Huang Y">Y. Huang</name></author><author><name sortKey="Tsoi, H W" uniqKey="Tsoi H">H.W. Tsoi</name></author><author><name sortKey="Wong, B H" uniqKey="Wong B">B.H. Wong</name></author><author><name sortKey="Wong, S S" uniqKey="Wong S">S.S. Wong</name></author><author><name sortKey="Leung, S Y" uniqKey="Leung S">S.Y. Leung</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Poon, R W" uniqKey="Poon R">R.W. Poon</name></author><author><name sortKey="Wong, B H" uniqKey="Wong B">B.H. Wong</name></author><author><name sortKey="Wang, M" uniqKey="Wang M">M. Wang</name></author><author><name sortKey="Huang, Y" uniqKey="Huang Y">Y. Huang</name></author><author><name sortKey="Xu, H" uniqKey="Xu H">H. Xu</name></author><author><name sortKey="Guo, R" uniqKey="Guo R">R. Guo</name></author><author><name sortKey="Li, K S" uniqKey="Li K">K.S. Li</name></author><author><name sortKey="Gao, K" uniqKey="Gao K">K. Gao</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Zheng, B J" uniqKey="Zheng B">B.J. Zheng</name></author><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Li, K S" uniqKey="Li K">K.S. Li</name></author><author><name sortKey="Tsang, A K" uniqKey="Tsang A">A.K. Tsang</name></author><author><name sortKey="Shek, C T" uniqKey="Shek C">C.T. Shek</name></author><author><name sortKey="Wang, M" uniqKey="Wang M">M. Wang</name></author><author><name sortKey="Choi, G K" uniqKey="Choi G">G.K. Choi</name></author><author><name sortKey="Guo, R" uniqKey="Guo R">R. Guo</name></author><author><name sortKey="Wong, B H" uniqKey="Wong B">B.H. Wong</name></author><author><name sortKey="Poon, R W" uniqKey="Poon R">R.W. Poon</name></author><author><name sortKey="Lam, C S" uniqKey="Lam C">C.S. Lam</name></author><author><name sortKey="Wang, S Y" uniqKey="Wang S">S.Y. Wang</name></author><author><name sortKey="Fan, R Y" uniqKey="Fan R">R.Y. Fan</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Zheng, B J" uniqKey="Zheng B">B.J. Zheng</name></author><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Feng, Y" uniqKey="Feng Y">Y. Feng</name></author><author><name sortKey="Chen, H" uniqKey="Chen H">H. Chen</name></author><author><name sortKey="Luk, H K" uniqKey="Luk H">H.K. Luk</name></author><author><name sortKey="Yang, W H" uniqKey="Yang W">W.H. Yang</name></author><author><name sortKey="Li, K S" uniqKey="Li K">K.S. Li</name></author><author><name sortKey="Zhang, Y Z" uniqKey="Zhang Y">Y.Z. Zhang</name></author><author><name sortKey="Huang, Y" uniqKey="Huang Y">Y. Huang</name></author><author><name sortKey="Song, Z Z" uniqKey="Song Z">Z.Z. Song</name></author><author><name sortKey="Chow, W N" uniqKey="Chow W">W.N. Chow</name></author><author><name sortKey="Fan, R Y" uniqKey="Fan R">R.Y. Fan</name></author><author><name sortKey="Ahmed, S S" uniqKey="Ahmed S">S.S. Ahmed</name></author><author><name sortKey="Yeung, H C" uniqKey="Yeung H">H.C. Yeung</name></author><author><name sortKey="Lam, C S" uniqKey="Lam C">C.S. Lam</name></author><author><name sortKey="Cai, J P" uniqKey="Cai J">J.P. Cai</name></author><author><name sortKey="Wong, S S" uniqKey="Wong S">S.S. Wong</name></author><author><name sortKey="Chan, J F" uniqKey="Chan J">J.F. Chan</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author><author><name sortKey="Zhang, H L" uniqKey="Zhang H">H.L. Zhang</name></author><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, W" uniqKey="Li W">W. Li</name></author><author><name sortKey="Shi, Z" uniqKey="Shi Z">Z. Shi</name></author><author><name sortKey="Yu, M" uniqKey="Yu M">M. Yu</name></author><author><name sortKey="Ren, W" uniqKey="Ren W">W. Ren</name></author><author><name sortKey="Smith, C" uniqKey="Smith C">C. Smith</name></author><author><name sortKey="Epstein, J H" uniqKey="Epstein J">J.H. Epstein</name></author><author><name sortKey="Wang, H" uniqKey="Wang H">H. Wang</name></author><author><name sortKey="Crameri, G" uniqKey="Crameri G">G. Crameri</name></author><author><name sortKey="Hu, Z" uniqKey="Hu Z">Z. Hu</name></author><author><name sortKey="Zhang, H" uniqKey="Zhang H">H. Zhang</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J. Zhang</name></author><author><name sortKey="Mceachern, J" uniqKey="Mceachern J">J. McEachern</name></author><author><name sortKey="Field, H" uniqKey="Field H">H. Field</name></author><author><name sortKey="Daszak, P" uniqKey="Daszak P">P. Daszak</name></author><author><name sortKey="Eaton, B T" uniqKey="Eaton B">B.T. Eaton</name></author><author><name sortKey="Zhang, S" uniqKey="Zhang S">S. Zhang</name></author><author><name sortKey="Wang, L F" uniqKey="Wang L">L.F. Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lole, K S" uniqKey="Lole K">K.S. Lole</name></author><author><name sortKey="Bollinger, R C" uniqKey="Bollinger R">R.C. Bollinger</name></author><author><name sortKey="Paranjape, R S" uniqKey="Paranjape R">R.S. Paranjape</name></author><author><name sortKey="Gadkari, D" uniqKey="Gadkari D">D. Gadkari</name></author><author><name sortKey="Kulkarni, S S" uniqKey="Kulkarni S">S.S. Kulkarni</name></author><author><name sortKey="Novak, N G" uniqKey="Novak N">N.G. Novak</name></author><author><name sortKey="Ingersoll, R" uniqKey="Ingersoll R">R. Ingersoll</name></author><author><name sortKey="Sheppard, H W" uniqKey="Sheppard H">H.W. Sheppard</name></author><author><name sortKey="Ray, S C" uniqKey="Ray S">S.C. Ray</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Martin, D P" uniqKey="Martin D">D.P. Martin</name></author><author><name sortKey="Murrell, B" uniqKey="Murrell B">B. Murrell</name></author><author><name sortKey="Golden, M" uniqKey="Golden M">M. Golden</name></author><author><name sortKey="Khoosal, A" uniqKey="Khoosal A">A. Khoosal</name></author><author><name sortKey="Muhire, B" uniqKey="Muhire B">B. Muhire</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Masters, P S" uniqKey="Masters P">P.S. Masters</name></author><author><name sortKey="Perlman, S" uniqKey="Perlman S">S. Perlman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nowak, R M" uniqKey="Nowak R">R.M. Nowak</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Lai, S T" uniqKey="Lai S">S.T. Lai</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Yam, L Y" uniqKey="Yam L">L.Y. Yam</name></author><author><name sortKey="Lim, W" uniqKey="Lim W">W. Lim</name></author><author><name sortKey="Nicholls, J" uniqKey="Nicholls J">J. Nicholls</name></author><author><name sortKey="Yee, W K" uniqKey="Yee W">W.K. Yee</name></author><author><name sortKey="Yan, W W" uniqKey="Yan W">W.W. Yan</name></author><author><name sortKey="Cheung, M T" uniqKey="Cheung M">M.T. Cheung</name></author><author><name sortKey="Cheng, V C" uniqKey="Cheng V">V.C. Cheng</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Tsang, D N" uniqKey="Tsang D">D.N. Tsang</name></author><author><name sortKey="Yung, R W" uniqKey="Yung R">R.W. Yung</name></author><author><name sortKey="Ng, T K" uniqKey="Ng T">T.K. Ng</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author><author><name sortKey="Chu, D K" uniqKey="Chu D">D.K. Chu</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Wong, O K" uniqKey="Wong O">O.K. Wong</name></author><author><name sortKey="Ellis, T M" uniqKey="Ellis T">T.M. Ellis</name></author><author><name sortKey="Leung, Y H" uniqKey="Leung Y">Y.H. Leung</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Suen, K Y" uniqKey="Suen K">K.Y. Suen</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shi, M" uniqKey="Shi M">M. Shi</name></author><author><name sortKey="Lin, X D" uniqKey="Lin X">X.D. Lin</name></author><author><name sortKey="Tian, J H" uniqKey="Tian J">J.H. Tian</name></author><author><name sortKey="Chen, L J" uniqKey="Chen L">L.J. Chen</name></author><author><name sortKey="Chen, X" uniqKey="Chen X">X. Chen</name></author><author><name sortKey="Li, C X" uniqKey="Li C">C.X. Li</name></author><author><name sortKey="Qin, X C" uniqKey="Qin X">X.C. Qin</name></author><author><name sortKey="Li, J" uniqKey="Li J">J. Li</name></author><author><name sortKey="Cao, J P" uniqKey="Cao J">J.P. Cao</name></author><author><name sortKey="Eden, J S" uniqKey="Eden J">J.S. Eden</name></author><author><name sortKey="Buchmann, J" uniqKey="Buchmann J">J. Buchmann</name></author><author><name sortKey="Wang, W" uniqKey="Wang W">W. Wang</name></author><author><name sortKey="Xu, J" uniqKey="Xu J">J. Xu</name></author><author><name sortKey="Holmes, E C" uniqKey="Holmes E">E.C. Holmes</name></author><author><name sortKey="Zhang, Y Z" uniqKey="Zhang Y">Y.Z. Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Smith, C S" uniqKey="Smith C">C.S. Smith</name></author><author><name sortKey="De Jong, C E" uniqKey="De Jong C">C.E. de Jong</name></author><author><name sortKey="Meers, J" uniqKey="Meers J">J. Meers</name></author><author><name sortKey="Henning, J" uniqKey="Henning J">J. Henning</name></author><author><name sortKey="Wang, L" uniqKey="Wang L">L. Wang</name></author><author><name sortKey="Field, H E" uniqKey="Field H">H.E. Field</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Talavera, G" uniqKey="Talavera G">G. Talavera</name></author><author><name sortKey="Castresana, J" uniqKey="Castresana J">J. Castresana</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tamura, K" uniqKey="Tamura K">K. Tamura</name></author><author><name sortKey="Peterson, D" uniqKey="Peterson D">D. Peterson</name></author><author><name sortKey="Peterson, N" uniqKey="Peterson N">N. Peterson</name></author><author><name sortKey="Stecher, G" uniqKey="Stecher G">G. Stecher</name></author><author><name sortKey="Nei, M" uniqKey="Nei M">M. Nei</name></author><author><name sortKey="Kumar, S" uniqKey="Kumar S">S. Kumar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tang, X C" uniqKey="Tang X">X.C. Tang</name></author><author><name sortKey="Zhang, J X" uniqKey="Zhang J">J.X. Zhang</name></author><author><name sortKey="Zhang, S Y" uniqKey="Zhang S">S.Y. Zhang</name></author><author><name sortKey="Wang, P" uniqKey="Wang P">P. Wang</name></author><author><name sortKey="Fan, X H" uniqKey="Fan X">X.H. Fan</name></author><author><name sortKey="Li, L F" uniqKey="Li L">L.F. Li</name></author><author><name sortKey="Li, G" uniqKey="Li G">G. Li</name></author><author><name sortKey="Dong, B Q" uniqKey="Dong B">B.Q. Dong</name></author><author><name sortKey="Liu, W" uniqKey="Liu W">W. Liu</name></author><author><name sortKey="Cheung, C L" uniqKey="Cheung C">C.L. Cheung</name></author><author><name sortKey="Xu, K M" uniqKey="Xu K">K.M. Xu</name></author><author><name sortKey="Song, W J" uniqKey="Song W">W.J. Song</name></author><author><name sortKey="Vijaykrishna, D" uniqKey="Vijaykrishna D">D. Vijaykrishna</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Smith, G J" uniqKey="Smith G">G.J. Smith</name></author><author><name sortKey="Chen, H" uniqKey="Chen H">H. Chen</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tao, Y" uniqKey="Tao Y">Y. Tao</name></author><author><name sortKey="Shi, M" uniqKey="Shi M">M. Shi</name></author><author><name sortKey="Chommanard, C" uniqKey="Chommanard C">C. Chommanard</name></author><author><name sortKey="Queen, K" uniqKey="Queen K">K. Queen</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J. Zhang</name></author><author><name sortKey="Markotter, W" uniqKey="Markotter W">W. Markotter</name></author><author><name sortKey="Kuzmin, I V" uniqKey="Kuzmin I">I.V. Kuzmin</name></author><author><name sortKey="Holmes, E C" uniqKey="Holmes E">E.C. Holmes</name></author><author><name sortKey="Tong, S" uniqKey="Tong S">S. Tong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vijaykrishna, D" uniqKey="Vijaykrishna D">D. Vijaykrishna</name></author><author><name sortKey="Smith, G J" uniqKey="Smith G">G.J. Smith</name></author><author><name sortKey="Zhang, J X" uniqKey="Zhang J">J.X. Zhang</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Chen, H" uniqKey="Chen H">H. Chen</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, W" uniqKey="Wang W">W. Wang</name></author><author><name sortKey="Lin, X D" uniqKey="Lin X">X.D. Lin</name></author><author><name sortKey="Guo, W P" uniqKey="Guo W">W.P. Guo</name></author><author><name sortKey="Zhou, R H" uniqKey="Zhou R">R.H. Zhou</name></author><author><name sortKey="Wang, M R" uniqKey="Wang M">M.R. Wang</name></author><author><name sortKey="Wang, C Q" uniqKey="Wang C">C.Q. Wang</name></author><author><name sortKey="Ge, S" uniqKey="Ge S">S. Ge</name></author><author><name sortKey="Mei, S H" uniqKey="Mei S">S.H. Mei</name></author><author><name sortKey="Li, M H" uniqKey="Li M">M.H. Li</name></author><author><name sortKey="Shi, M" uniqKey="Shi M">M. Shi</name></author><author><name sortKey="Holmes, E C" uniqKey="Holmes E">E.C. Holmes</name></author><author><name sortKey="Zhang, Y Z" uniqKey="Zhang Y">Y.Z. Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wertheim, J O" uniqKey="Wertheim J">J.O. Wertheim</name></author><author><name sortKey="Chu, D K" uniqKey="Chu D">D.K. Chu</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Kosakovsky Pond, S L" uniqKey="Kosakovsky Pond S">S.L. Kosakovsky Pond</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Huang, Y" uniqKey="Huang Y">Y. Huang</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Li, K S" uniqKey="Li K">K.S. Li</name></author><author><name sortKey="Poon, R W" uniqKey="Poon R">R.W. Poon</name></author><author><name sortKey="Wong, B H" uniqKey="Wong B">B.H. Wong</name></author><author><name sortKey="Tsoi, H W" uniqKey="Tsoi H">H.W. Tsoi</name></author><author><name sortKey="Yip, B C" uniqKey="Yip B">B.C. Yip</name></author><author><name sortKey="Huang, Y" uniqKey="Huang Y">Y. Huang</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Lam, C S" uniqKey="Lam C">C.S. Lam</name></author><author><name sortKey="Lau, C C" uniqKey="Lau C">C.C. Lau</name></author><author><name sortKey="Tsang, A K" uniqKey="Tsang A">A.K. Tsang</name></author><author><name sortKey="Lau, J H" uniqKey="Lau J">J.H. Lau</name></author><author><name sortKey="Bai, R" uniqKey="Bai R">R. Bai</name></author><author><name sortKey="Teng, J L" uniqKey="Teng J">J.L. Teng</name></author><author><name sortKey="Tsang, C C" uniqKey="Tsang C">C.C. Tsang</name></author><author><name sortKey="Wang, M" uniqKey="Wang M">M. Wang</name></author><author><name sortKey="Zheng, B J" uniqKey="Zheng B">B.J. Zheng</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Chu, C M" uniqKey="Chu C">C.M. Chu</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Tsoi, H W" uniqKey="Tsoi H">H.W. Tsoi</name></author><author><name sortKey="Huang, Y" uniqKey="Huang Y">Y. Huang</name></author><author><name sortKey="Wong, B H" uniqKey="Wong B">B.H. Wong</name></author><author><name sortKey="Poon, R W" uniqKey="Poon R">R.W. Poon</name></author><author><name sortKey="Cai, J J" uniqKey="Cai J">J.J. Cai</name></author><author><name sortKey="Luk, W K" uniqKey="Luk W">W.K. Luk</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author><author><name sortKey="Wong, S S" uniqKey="Wong S">S.S. Wong</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, Z" uniqKey="Wu Z">Z. Wu</name></author><author><name sortKey="Yang, L" uniqKey="Yang L">L. Yang</name></author><author><name sortKey="Ren, X" uniqKey="Ren X">X. Ren</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J. Zhang</name></author><author><name sortKey="Yang, F" uniqKey="Yang F">F. Yang</name></author><author><name sortKey="Zhang, S" uniqKey="Zhang S">S. Zhang</name></author><author><name sortKey="Jin, Q" uniqKey="Jin Q">Q. Jin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, L" uniqKey="Yang L">L. Yang</name></author><author><name sortKey="Wu, Z" uniqKey="Wu Z">Z. Wu</name></author><author><name sortKey="Ren, X" uniqKey="Ren X">X. Ren</name></author><author><name sortKey="Yang, F" uniqKey="Yang F">F. Yang</name></author><author><name sortKey="He, G" uniqKey="He G">G. He</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J. Zhang</name></author><author><name sortKey="Dong, J" uniqKey="Dong J">J. Dong</name></author><author><name sortKey="Sun, L" uniqKey="Sun L">L. Sun</name></author><author><name sortKey="Zhu, Y" uniqKey="Zhu Y">Y. Zhu</name></author><author><name sortKey="Du, J" uniqKey="Du J">J. Du</name></author><author><name sortKey="Zhang, S" uniqKey="Zhang S">S. Zhang</name></author><author><name sortKey="Jin, Q" uniqKey="Jin Q">Q. Jin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, X L" uniqKey="Yang X">X.L. Yang</name></author><author><name sortKey="Hu, B" uniqKey="Hu B">B. Hu</name></author><author><name sortKey="Wang, B" uniqKey="Wang B">B. Wang</name></author><author><name sortKey="Wang, M N" uniqKey="Wang M">M.N. Wang</name></author><author><name sortKey="Zhang, Q" uniqKey="Zhang Q">Q. Zhang</name></author><author><name sortKey="Zhang, W" uniqKey="Zhang W">W. Zhang</name></author><author><name sortKey="Wu, L J" uniqKey="Wu L">L.J. Wu</name></author><author><name sortKey="Ge, X Y" uniqKey="Ge X">X.Y. Ge</name></author><author><name sortKey="Zhang, Y Z" uniqKey="Zhang Y">Y.Z. Zhang</name></author><author><name sortKey="Daszak, P" uniqKey="Daszak P">P. Daszak</name></author><author><name sortKey="Wang, L F" uniqKey="Wang L">L.F. Wang</name></author><author><name sortKey="Shi, Z L" uniqKey="Shi Z">Z.L. Shi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zaki, A M" uniqKey="Zaki A">A.M. Zaki</name></author><author><name sortKey="Van Boheemen, S" uniqKey="Van Boheemen S">S. van Boheemen</name></author><author><name sortKey="Bestebroer, T M" uniqKey="Bestebroer T">T.M. Bestebroer</name></author><author><name sortKey="Osterhaus, A D" uniqKey="Osterhaus A">A.D. Osterhaus</name></author><author><name sortKey="Fouchier, R A" uniqKey="Fouchier R">R.A. Fouchier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, R Z" uniqKey="Zhang R">R.Z. Zhang</name></author><author><name sortKey="Jing, S K" uniqKey="Jing S">S.K. Jing</name></author><author><name sortKey="Quan, G Q" uniqKey="Quan G">G.Q. Quan</name></author><author><name sortKey="Li, S H" uniqKey="Li S">S.H. Li</name></author><author><name sortKey="Ye, Z Y" uniqKey="Ye Z">Z.Y. Ye</name></author><author><name sortKey="Wang, F G" uniqKey="Wang F">F.G. Wang</name></author><author><name sortKey="Zhang, M L" uniqKey="Zhang M">M.L. Zhang</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Virology</journal-id><journal-id journal-id-type="iso-abbrev">Virology</journal-id><journal-title-group><journal-title>Virology</journal-title></journal-title-group><issn pub-type="ppub">0042-6822</issn><issn pub-type="epub">1096-0341</issn><publisher><publisher-name>Elsevier Inc.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">28384506</article-id><article-id pub-id-type="pmc">7111643</article-id><article-id pub-id-type="publisher-id">S0042-6822(17)30100-9</article-id><article-id pub-id-type="doi">10.1016/j.virol.2017.03.019</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Extensive diversity of coronaviruses in bats from China</article-title></title-group><contrib-group><contrib contrib-type="author" id="au0005"><name><surname>Lin</surname><given-names>Xian-Dan</given-names></name><xref rid="aff0005" ref-type="aff">a</xref><xref rid="aff0010" ref-type="aff">b</xref><xref rid="fn1" ref-type="fn">1</xref></contrib><contrib contrib-type="author" id="au0010"><name><surname>Wang</surname><given-names>Wen</given-names></name><xref rid="aff0005" ref-type="aff">a</xref><xref rid="fn1" ref-type="fn">1</xref></contrib><contrib contrib-type="author" id="au0015"><name><surname>Hao</surname><given-names>Zong-Yu</given-names></name><xref rid="aff0015" ref-type="aff">c</xref><xref rid="fn1" ref-type="fn">1</xref></contrib><contrib contrib-type="author" id="au0020"><name><surname>Wang</surname><given-names>Zhao-Xiao</given-names></name><xref rid="aff0020" ref-type="aff">d</xref><xref rid="fn1" ref-type="fn">1</xref></contrib><contrib contrib-type="author" id="au0025"><name><surname>Guo</surname><given-names>Wen-Ping</given-names></name><xref rid="aff0005" ref-type="aff">a</xref></contrib><contrib contrib-type="author" id="au0030"><name><surname>Guan</surname><given-names>Xiao-Qing</given-names></name><xref rid="aff0005" ref-type="aff">a</xref></contrib><contrib contrib-type="author" id="au0035"><name><surname>Wang</surname><given-names>Miao-Ruo</given-names></name><xref rid="aff0025" ref-type="aff">e</xref></contrib><contrib contrib-type="author" id="au0040"><name><surname>Wang</surname><given-names>Hong-Wei</given-names></name><xref rid="aff0030" ref-type="aff">f</xref></contrib><contrib contrib-type="author" id="au0045"><name><surname>Zhou</surname><given-names>Run-Hong</given-names></name><xref rid="aff0005" ref-type="aff">a</xref></contrib><contrib contrib-type="author" id="au0050"><name><surname>Li</surname><given-names>Ming-Hui</given-names></name><xref rid="aff0005" ref-type="aff">a</xref></contrib><contrib contrib-type="author" id="au0055"><name><surname>Tang</surname><given-names>Guang-Peng</given-names></name><xref rid="aff0020" ref-type="aff">d</xref></contrib><contrib contrib-type="author" id="au0060"><name><surname>Wu</surname><given-names>Jun</given-names></name><xref rid="aff0035" ref-type="aff">g</xref></contrib><contrib contrib-type="author" id="au0065"><name><surname>Holmes</surname><given-names>Edward C.</given-names></name><xref rid="aff0040" ref-type="aff">h</xref></contrib><contrib contrib-type="author" id="au0070"><name><surname>Zhang</surname><given-names>Yong-Zhen</given-names></name><email>zhangyongzhen@icdc.cn</email><xref rid="aff0005" ref-type="aff">a</xref><xref rid="cor1" ref-type="corresp">⁎</xref></contrib></contrib-group><aff id="aff0005"><label>a</label>State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Zoonoses, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing, China</aff><aff id="aff0010"><label>b</label>Wenzhou Center for Disease Control and Prevention, Wenzhou, Zhejiang Province, China</aff><aff id="aff0015"><label>c</label>Henan Center for Disease Control and Prevention, Zhengzhou, Henan Province, China</aff><aff id="aff0020"><label>d</label>Guizhou Center for Disease Control and Prevention, Guiyang, Guizhou Province, China</aff><aff id="aff0025"><label>e</label>Longquan Center for Disease Control and Prevention, Longquan, Zhejiang Province, China</aff><aff id="aff0030"><label>f</label>Neixiang Center for Disease Control and Prevention, Neixiang, Henan Province, China</aff><aff id="aff0035"><label>g</label>Jiyuan Center for Disease Control and Prevention, Jiyuan, Henan Province, China</aff><aff id="aff0040"><label>h</label>Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, School of Life and Environmental Sciences and Sydney Medical School, The University of Sydney, Sydney, NSW 2006, Australia</aff><author-notes><corresp id="cor1"><label>⁎</label>Correspondence to: State Key Laboratory for Infectious Disease Prevention and Control, National Institute of Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping Liuzi 5, Beijing 102206, China. <email>zhangyongzhen@icdc.cn</email></corresp><fn id="fn1"><label>1</label><p id="ntp0005">Contributed to this work equally.</p></fn></author-notes><pub-date pub-type="pmc-release"><day>3</day><month>4</month><year>2017</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><month>7</month><year>2017</year></pub-date><pub-date pub-type="epub"><day>3</day><month>4</month><year>2017</year></pub-date><volume>507</volume><fpage>1</fpage><lpage>10</lpage><history><date date-type="received"><day>12</day><month>2</month><year>2017</year></date><date date-type="rev-recd"><day>27</day><month>3</month><year>2017</year></date><date date-type="accepted"><day>28</day><month>3</month><year>2017</year></date></history><permissions><copyright-statement>© 2017 Elsevier Inc.</copyright-statement><copyright-year>2017</copyright-year><copyright-holder>Elsevier Inc.</copyright-holder><license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p></license></permissions><abstract id="ab0010"><p>To help reveal the diversity and evolution of bat coronaviruses we collected 1067 bats from 21 species in China. A total of 73 coronaviruses (32 alphacoronaviruses and 41 betacoronaviruses) were identified in these bats, with an overall prevalence of 6.84%. All newly-identified betacoronaviruses were SARS-related Rhinolophus bat coronaviruses (SARSr-Rh-BatCoV). Importantly, with the exception of the S gene, the genome sequences of the SARSr-Rh-BatCoVs sampled in Guizhou province were closely related to SARS-related human coronavirus. Additionally, the newly-identified alphacoronaviruses exhibited high genetic diversity and some may represent novel species. Our phylogenetic analyses also provided insights into the transmission of these viruses among bat species, revealing a general clustering by geographic location rather than by bat species. Inter-species transmission among bats from the same genus was also commonplace in both the alphacoronaviruses and betacoronaviruses. Overall, these data suggest that high contact rates among specific bat species enable the acquisition and spread of coronaviruses.</p></abstract><abstract abstract-type="author-highlights" id="ab0015"><title>Highlights</title><p><list list-type="simple" id="li0005"><list-item id="u0005"><label>•</label><p id="p0005">32 alpha-CoVs and 41 beta-CoVs were identified in bats sampled from China.</p></list-item><list-item id="u0010"><label>•</label><p id="p0010">SARSr-Rh-BatCoVs from Guizhou province were closely related to SARS-CoV.</p></list-item><list-item id="u0015"><label>•</label><p id="p0015">Some of the newly identified CoVs may be novel species in the genus <italic>Alphacoronavirus</italic>.</p></list-item><list-item id="u0020"><label>•</label><p id="p0020">High contact rates among some bat species enable the acquisition and spread of CoVs.</p></list-item></list></p></abstract><kwd-group id="keys0005"><title>Keywords</title><kwd>Bats</kwd><kwd>Coronavirus</kwd><kwd>Evolution</kwd><kwd>Phylogeny</kwd><kwd>Transmission</kwd><kwd>SARS</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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