SARS: future research and vaccine
Identifieur interne : 001418 ( Pmc/Curation ); précédent : 001417; suivant : 001419SARS: future research and vaccine
Auteurs : Yu-Lung LauSource :
- Paediatric Respiratory Reviews [ 1526-0542 ] ; 2004.
Abstract
Severe acute respiratory syndrome (SARS) is a new infectious disease of the 21st century that has pandemic potential. A novel coronavirus (CoV) was identified as its aetiological agent and its genome was sequenced within months of the World Health Organisation issuing a global threat on SARS. The high morbidity and mortality of this potentially pandemic infection demands a rapid research response to develop effective antiviral treatment and vaccine. This will depend on understanding the pathogenesis and immune response to SARS CoV. Further understanding of the ecology of SARS CoV in human and animals will help prevent future cross species transmission. Likewise for the super-spreading events, clarification of the underlying reasons will be important to prevent a large scale outbreak of SARS. Lastly it is of utmost importance that international research collaboration should be strengthened to deal with SARS and any other emerging infectious disease that can seriously threaten our future.
Url:
DOI: 10.1016/j.prrv.2004.07.005
PubMed: 15531254
PubMed Central: 7106257
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">SARS: future research and vaccine</title><author><name sortKey="Lau, Yu Lung" sort="Lau, Yu Lung" uniqKey="Lau Y" first="Yu-Lung" last="Lau">Yu-Lung Lau</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">15531254</idno><idno type="pmc">7106257</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106257</idno><idno type="RBID">PMC:7106257</idno><idno type="doi">10.1016/j.prrv.2004.07.005</idno><date when="2004">2004</date><idno type="wicri:Area/Pmc/Corpus">001418</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001418</idno><idno type="wicri:Area/Pmc/Curation">001418</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001418</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">SARS: future research and vaccine</title><author><name sortKey="Lau, Yu Lung" sort="Lau, Yu Lung" uniqKey="Lau Y" first="Yu-Lung" last="Lau">Yu-Lung Lau</name></author></analytic><series><title level="j">Paediatric Respiratory Reviews</title><idno type="ISSN">1526-0542</idno><idno type="eISSN">1526-0550</idno><imprint><date when="2004">2004</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Summary</title><p>Severe acute respiratory syndrome (SARS) is a new infectious disease of the 21st century that has pandemic potential. A novel coronavirus (CoV) was identified as its aetiological agent and its genome was sequenced within months of the World Health Organisation issuing a global threat on SARS. The high morbidity and mortality of this potentially pandemic infection demands a rapid research response to develop effective antiviral treatment and vaccine. This will depend on understanding the pathogenesis and immune response to SARS CoV. Further understanding of the ecology of SARS CoV in human and animals will help prevent future cross species transmission. Likewise for the super-spreading events, clarification of the underlying reasons will be important to prevent a large scale outbreak of SARS. Lastly it is of utmost importance that international research collaboration should be strengthened to deal with SARS and any other emerging infectious disease that can seriously threaten our future.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Peiris, J S M" uniqKey="Peiris J">J.S.M. Peiris</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author><author><name sortKey="Osterhaus, A D M E" uniqKey="Osterhaus A">A.D.M.E. Osterhaus</name></author><author><name sortKey="Stohr, K" uniqKey="Stohr K">K. Stohr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Peiris, J S M" uniqKey="Peiris J">J.S.M. Peiris</name></author><author><name sortKey="Lai, S T" uniqKey="Lai S">S.T. Lai</name></author><author><name sortKey="Poon, L L M" uniqKey="Poon L">L.L.M. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Paediatr Respir Rev</journal-id><journal-id journal-id-type="iso-abbrev">Paediatr Respir Rev</journal-id><journal-title-group><journal-title>Paediatric Respiratory Reviews</journal-title></journal-title-group><issn pub-type="ppub">1526-0542</issn><issn pub-type="epub">1526-0550</issn><publisher><publisher-name>Elsevier Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">15531254</article-id><article-id pub-id-type="pmc">7106257</article-id><article-id pub-id-type="publisher-id">S1526-0542(04)00074-0</article-id><article-id pub-id-type="doi">10.1016/j.prrv.2004.07.005</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>SARS: future research and vaccine</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Lau</surname><given-names>Yu-Lung</given-names></name><email>lauylung@hkucc.hku.hk</email><xref rid="cor1" ref-type="corresp">*</xref></contrib></contrib-group><aff>Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong</aff><author-notes><corresp id="cor1"><label>*</label>Correspondence to: Y.-L. Lau. Tel.: +852 2855 4481; Fax: +852 2855 1523 <email>lauylung@hkucc.hku.hk</email></corresp></author-notes><pub-date pub-type="pmc-release"><day>5</day><month>11</month><year>2004</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><month>12</month><year>2004</year></pub-date><pub-date pub-type="epub"><day>5</day><month>11</month><year>2004</year></pub-date><volume>5</volume><issue>4</issue><fpage>300</fpage><lpage>303</lpage><permissions><copyright-statement>Copyright © 2004 Elsevier Ltd. All rights reserved.</copyright-statement><copyright-year>2004</copyright-year><copyright-holder>Elsevier Ltd</copyright-holder><license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p></license></permissions><abstract><title>Summary</title><p>Severe acute respiratory syndrome (SARS) is a new infectious disease of the 21st century that has pandemic potential. A novel coronavirus (CoV) was identified as its aetiological agent and its genome was sequenced within months of the World Health Organisation issuing a global threat on SARS. The high morbidity and mortality of this potentially pandemic infection demands a rapid research response to develop effective antiviral treatment and vaccine. This will depend on understanding the pathogenesis and immune response to SARS CoV. Further understanding of the ecology of SARS CoV in human and animals will help prevent future cross species transmission. Likewise for the super-spreading events, clarification of the underlying reasons will be important to prevent a large scale outbreak of SARS. Lastly it is of utmost importance that international research collaboration should be strengthened to deal with SARS and any other emerging infectious disease that can seriously threaten our future.</p></abstract><kwd-group><title>KEYWORDS</title><kwd>SARS</kwd><kwd>coronavirus</kwd><kwd>antiviral</kwd><kwd>vaccine</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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