COVID-19 pneumonia manifestations at the admission on chest ultrasound, radiographs, and CT: single-center study and comprehensive radiologic literature review
Identifieur interne : 000F93 ( Pmc/Curation ); précédent : 000F92; suivant : 000F94COVID-19 pneumonia manifestations at the admission on chest ultrasound, radiographs, and CT: single-center study and comprehensive radiologic literature review
Auteurs : Pascal Lomoro [Italie] ; Francesco Verde [Italie] ; Filippo Zerboni [Italie] ; Igino Simonetti [Italie] ; Claudia Borghi [Italie] ; Camilla Fachinetti [Italie] ; Anna Natalizi [Italie] ; Alberto Martegani [Italie]Source :
- European Journal of Radiology Open [ 2352-0477 ] ; 2020.
Abstract
To investigate the imaging features of emerging COVID-19 pneumonia on chest ultrasound (US), radiographs (CXR) and computed tomography (CT) examinations performed at admission and to provide a comprehensive radiological literature review on ongoing radiological data from recent publications.
In this retrospective single-center study, we enrolled consecutive patients from February 15, 2020, to March 15, 2020, with laboratory-confirmed SARS-CoV-2 hospitalized in Valduce Hospital (Como, Italy). Multi-modality imaging findings were evaluated and compared. Literature research was conducted through a methodical search on Pubmed and Embase databases.
Fifty-eight patients (36 men, 22 women; age range, 18–98 years) were included in the study. Among these, chest US, CXR, and CT were performed respectively in twenty-two, thirty-two and forty-two patients. Lung US findings were consistent with diffuse B lines (100%) and subpleural consolidations (27.3%). CXR showed prevalent manifestations of consolidations (46.9%) and hazy increased opacities (37.5%). Typical CT features included bilateral and multilobar ground-glass opacities (GGO) with (59.5%) and without (35.7%) consolidations having a predominantly peripheral distribution (64.3%). Other imaging features included crazy paving pattern (57.1%), fibrous stripes (50%), subpleural lines (35.7%), architectural distortion (28.6%), air bronchogram sign (26.2%), vascular thickening (23.8%) and nodules (2.4%). Also, enlarged lymph nodes (14.3 %) and pleural effusion (7.1%) were observed. The literature review identified twenty-six original studies supporting our imaging chest findings.
The spectrum of chest imaging manifestations of COVID-19 pneumonia upon admission includes B-lines and consolidations on US, consolidations and hazy increased opacities on CXR, and multifocal GGO with consolidations on CT.
Url:
DOI: 10.1016/j.ejro.2020.100231
PubMed: 32289051
PubMed Central: 7129441
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of Advanced Biomedical Sciences</wicri:regionArea></affiliation></author><author><name sortKey="Zerboni, Filippo" sort="Zerboni, Filippo" uniqKey="Zerboni F" first="Filippo" last="Zerboni">Filippo Zerboni</name><affiliation wicri:level="1"><nlm:aff id="aff0005">Radiology Department, Valduce Hospital, Como, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Radiology Department, Valduce Hospital, Como</wicri:regionArea></affiliation></author><author><name sortKey="Simonetti, Igino" sort="Simonetti, Igino" uniqKey="Simonetti I" first="Igino" last="Simonetti">Igino Simonetti</name><affiliation wicri:level="1"><nlm:aff id="aff0010">University of Naples Federico II, Department of Advanced Biomedical Sciences, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>University of Naples Federico II, Department of Advanced Biomedical Sciences</wicri:regionArea></affiliation></author><author><name sortKey="Borghi, Claudia" sort="Borghi, Claudia" uniqKey="Borghi C" first="Claudia" last="Borghi">Claudia Borghi</name><affiliation wicri:level="1"><nlm:aff id="aff0005">Radiology Department, Valduce Hospital, Como, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Radiology Department, Valduce Hospital, Como</wicri:regionArea></affiliation></author><author><name sortKey="Fachinetti, Camilla" sort="Fachinetti, Camilla" uniqKey="Fachinetti C" first="Camilla" last="Fachinetti">Camilla Fachinetti</name><affiliation wicri:level="1"><nlm:aff id="aff0005">Radiology Department, Valduce Hospital, Como, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Radiology Department, Valduce Hospital, Como</wicri:regionArea></affiliation></author><author><name sortKey="Natalizi, Anna" sort="Natalizi, Anna" uniqKey="Natalizi A" first="Anna" last="Natalizi">Anna Natalizi</name><affiliation wicri:level="1"><nlm:aff id="aff0015">Emergency Department, Valduce Hospital, Como, Italy</nlm:aff><country 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id="aff0010">University of Naples Federico II, Department of Advanced Biomedical Sciences, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>University of Naples Federico II, Department of Advanced Biomedical Sciences</wicri:regionArea></affiliation></author><author><name sortKey="Zerboni, Filippo" sort="Zerboni, Filippo" uniqKey="Zerboni F" first="Filippo" last="Zerboni">Filippo Zerboni</name><affiliation wicri:level="1"><nlm:aff id="aff0005">Radiology Department, Valduce Hospital, Como, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Radiology Department, Valduce Hospital, Como</wicri:regionArea></affiliation></author><author><name sortKey="Simonetti, Igino" sort="Simonetti, Igino" uniqKey="Simonetti I" first="Igino" last="Simonetti">Igino Simonetti</name><affiliation wicri:level="1"><nlm:aff id="aff0010">University of Naples Federico II, Department of Advanced Biomedical Sciences, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>University of Naples Federico II, Department of Advanced Biomedical Sciences</wicri:regionArea></affiliation></author><author><name sortKey="Borghi, Claudia" sort="Borghi, Claudia" uniqKey="Borghi C" first="Claudia" last="Borghi">Claudia Borghi</name><affiliation wicri:level="1"><nlm:aff id="aff0005">Radiology Department, Valduce Hospital, Como, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Radiology Department, Valduce Hospital, Como</wicri:regionArea></affiliation></author><author><name sortKey="Fachinetti, Camilla" sort="Fachinetti, Camilla" uniqKey="Fachinetti C" first="Camilla" last="Fachinetti">Camilla Fachinetti</name><affiliation wicri:level="1"><nlm:aff id="aff0005">Radiology Department, Valduce Hospital, Como, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Radiology Department, Valduce Hospital, Como</wicri:regionArea></affiliation></author><author><name sortKey="Natalizi, Anna" sort="Natalizi, Anna" uniqKey="Natalizi A" first="Anna" last="Natalizi">Anna Natalizi</name><affiliation wicri:level="1"><nlm:aff id="aff0015">Emergency Department, Valduce Hospital, Como, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Emergency Department, Valduce Hospital, Como</wicri:regionArea></affiliation></author><author><name sortKey="Martegani, Alberto" sort="Martegani, Alberto" uniqKey="Martegani A" first="Alberto" last="Martegani">Alberto Martegani</name><affiliation wicri:level="1"><nlm:aff id="aff0005">Radiology Department, Valduce Hospital, Como, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Radiology Department, Valduce Hospital, Como</wicri:regionArea></affiliation></author></analytic><series><title level="j">European Journal of Radiology Open</title><idno type="eISSN">2352-0477</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Purpose</title><p>To investigate the imaging features of emerging COVID-19 pneumonia on chest ultrasound (US), radiographs (CXR) and computed tomography (CT) examinations performed at admission and to provide a comprehensive radiological literature review on ongoing radiological data from recent publications.</p></sec><sec><title>Materials and methods</title><p>In this retrospective single-center study, we enrolled consecutive patients from February 15, 2020, to March 15, 2020, with laboratory-confirmed SARS-CoV-2 hospitalized in Valduce Hospital (Como, Italy). Multi-modality imaging findings were evaluated and compared. Literature research was conducted through a methodical search on Pubmed and Embase databases.</p></sec><sec><title>Results</title><p>Fifty-eight patients (36 men, 22 women; age range, 18–98 years) were included in the study. Among these, chest US, CXR, and CT were performed respectively in twenty-two, thirty-two and forty-two patients. Lung US findings were consistent with diffuse B lines (100%) and subpleural consolidations (27.3%). CXR showed prevalent manifestations of consolidations (46.9%) and hazy increased opacities (37.5%). Typical CT features included bilateral and multilobar ground-glass opacities (GGO) with (59.5%) and without (35.7%) consolidations having a predominantly peripheral distribution (64.3%). Other imaging features included crazy paving pattern (57.1%), fibrous stripes (50%), subpleural lines (35.7%), architectural distortion (28.6%), air bronchogram sign (26.2%), vascular thickening (23.8%) and nodules (2.4%). Also, enlarged lymph nodes (14.3 %) and pleural effusion (7.1%) were observed. The literature review identified twenty-six original studies supporting our imaging chest findings.</p></sec><sec><title>Conclusion</title><p>The spectrum of chest imaging manifestations of COVID-19 pneumonia upon admission includes B-lines and consolidations on US, consolidations and hazy increased opacities on CXR, and multifocal GGO with consolidations on CT.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Rothan, H A" uniqKey="Rothan H">H.A. Rothan</name></author><author><name sortKey="Byrareddy, S N" uniqKey="Byrareddy S">S.N. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Eur J Radiol Open</journal-id><journal-id journal-id-type="iso-abbrev">Eur J Radiol Open</journal-id><journal-title-group><journal-title>European Journal of Radiology Open</journal-title></journal-title-group><issn pub-type="epub">2352-0477</issn><publisher><publisher-name>The Author(s). Published by Elsevier Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">32289051</article-id><article-id pub-id-type="pmc">7129441</article-id><article-id pub-id-type="publisher-id">S2352-0477(20)30020-4</article-id><article-id pub-id-type="doi">10.1016/j.ejro.2020.100231</article-id><article-id pub-id-type="publisher-id">100231</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>COVID-19 pneumonia manifestations at the admission on chest ultrasound, radiographs, and CT: single-center study and comprehensive radiologic literature review</article-title></title-group><contrib-group><contrib contrib-type="author" id="aut0005"><name><surname>Lomoro</surname><given-names>Pascal</given-names></name><email>lmr.pcl89@gmail.com</email><xref rid="aff0005" ref-type="aff">a</xref></contrib><contrib contrib-type="author" id="aut0010"><name><surname>Verde</surname><given-names>Francesco</given-names></name><email>francescoverde87@gmail.com</email><xref rid="aff0010" ref-type="aff">b</xref></contrib><contrib contrib-type="author" id="aut0015"><name><surname>Zerboni</surname><given-names>Filippo</given-names></name><email>fzerboni@valduce.it</email><xref rid="aff0005" ref-type="aff">a</xref></contrib><contrib contrib-type="author" id="aut0020"><name><surname>Simonetti</surname><given-names>Igino</given-names></name><email>igino.simonetti@gmail.com</email><xref rid="aff0010" ref-type="aff">b</xref><xref rid="cor0005" ref-type="corresp">*</xref></contrib><contrib contrib-type="author" id="aut0025"><name><surname>Borghi</surname><given-names>Claudia</given-names></name><email>clborghi@libero.it</email><xref rid="aff0005" ref-type="aff">a</xref></contrib><contrib contrib-type="author" id="aut0030"><name><surname>Fachinetti</surname><given-names>Camilla</given-names></name><email>camifachinetti@gmail.com</email><xref rid="aff0005" ref-type="aff">a</xref></contrib><contrib contrib-type="author" id="aut0035"><name><surname>Natalizi</surname><given-names>Anna</given-names></name><email>an.natalizi@gmail.com</email><xref rid="aff0015" ref-type="aff">c</xref></contrib><contrib contrib-type="author" id="aut0040"><name><surname>Martegani</surname><given-names>Alberto</given-names></name><email>amartegani@valduce.it</email><xref rid="aff0005" ref-type="aff">a</xref></contrib></contrib-group><aff id="aff0005"><label>a</label>Radiology Department, Valduce Hospital, Como, Italy</aff><aff id="aff0010"><label>b</label>University of Naples Federico II, Department of Advanced Biomedical Sciences, Italy</aff><aff id="aff0015"><label>c</label>Emergency Department, Valduce Hospital, Como, Italy</aff><author-notes><corresp id="cor0005"><label>⁎</label>Corresponding author at: Department of Advanced Biomedical Sciences, University of Naples Federico II, Via Sergio Pansini, 5, 80131, Napoli, Italy. <email>igino.simonetti@gmail.com</email></corresp></author-notes><pub-date pub-type="pmc-release"><day>4</day><month>4</month><year>2020</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><year>2020</year></pub-date><pub-date pub-type="epub"><day>4</day><month>4</month><year>2020</year></pub-date><volume>7</volume><fpage>100231</fpage><lpage>100231</lpage><history><date date-type="received"><day>20</day><month>3</month><year>2020</year></date><date date-type="rev-recd"><day>31</day><month>3</month><year>2020</year></date><date date-type="accepted"><day>1</day><month>4</month><year>2020</year></date></history><permissions><copyright-statement>© 2020 The Author(s)</copyright-statement><copyright-year>2020</copyright-year><license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p></license></permissions><abstract id="abs0005"><sec><title>Purpose</title><p>To investigate the imaging features of emerging COVID-19 pneumonia on chest ultrasound (US), radiographs (CXR) and computed tomography (CT) examinations performed at admission and to provide a comprehensive radiological literature review on ongoing radiological data from recent publications.</p></sec><sec><title>Materials and methods</title><p>In this retrospective single-center study, we enrolled consecutive patients from February 15, 2020, to March 15, 2020, with laboratory-confirmed SARS-CoV-2 hospitalized in Valduce Hospital (Como, Italy). Multi-modality imaging findings were evaluated and compared. Literature research was conducted through a methodical search on Pubmed and Embase databases.</p></sec><sec><title>Results</title><p>Fifty-eight patients (36 men, 22 women; age range, 18–98 years) were included in the study. Among these, chest US, CXR, and CT were performed respectively in twenty-two, thirty-two and forty-two patients. Lung US findings were consistent with diffuse B lines (100%) and subpleural consolidations (27.3%). CXR showed prevalent manifestations of consolidations (46.9%) and hazy increased opacities (37.5%). Typical CT features included bilateral and multilobar ground-glass opacities (GGO) with (59.5%) and without (35.7%) consolidations having a predominantly peripheral distribution (64.3%). Other imaging features included crazy paving pattern (57.1%), fibrous stripes (50%), subpleural lines (35.7%), architectural distortion (28.6%), air bronchogram sign (26.2%), vascular thickening (23.8%) and nodules (2.4%). Also, enlarged lymph nodes (14.3 %) and pleural effusion (7.1%) were observed. The literature review identified twenty-six original studies supporting our imaging chest findings.</p></sec><sec><title>Conclusion</title><p>The spectrum of chest imaging manifestations of COVID-19 pneumonia upon admission includes B-lines and consolidations on US, consolidations and hazy increased opacities on CXR, and multifocal GGO with consolidations on CT.</p></sec></abstract><kwd-group id="kwd0005"><title>Keywords</title><kwd>coronavirus disease</kwd><kwd>COVID-19</kwd><kwd>Computed Tomography (CT)</kwd><kwd>pneumonia</kwd><kwd>SARS-CoV-2</kwd><kwd>ultrasound (US)</kwd><kwd>radiographic chest examination (CXR)</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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