Viral Load Distribution in SARS Outbreak
Identifieur interne : 000F73 ( Pmc/Curation ); précédent : 000F72; suivant : 000F74Viral Load Distribution in SARS Outbreak
Auteurs : Chung-Ming Chu [République populaire de Chine] ; Vincent C. C. Cheng [République populaire de Chine] ; Ivan F. N. Hung [République populaire de Chine] ; Kin-Sang Chan [République populaire de Chine] ; Bone S. F. Tang [République populaire de Chine] ; Thomas H. F. Tsang [République populaire de Chine] ; Kwok-Hung Chan [République populaire de Chine] ; Kwok-Yung Yuen [République populaire de Chine]Source :
- Emerging Infectious Diseases [ 1080-6040 ] ; 2005.
Abstract
Airborne transmission may have resulted in an outbreak of SARS in Hong Kong.
Url:
DOI: 10.3201/eid1112.040949
PubMed: 16485474
PubMed Central: 3367618
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<front><journal-meta><journal-id journal-id-type="nlm-ta">Emerg Infect Dis</journal-id><journal-id journal-id-type="iso-abbrev">Emerging Infect. Dis</journal-id><journal-id journal-id-type="publisher-id">EID</journal-id><journal-title-group><journal-title>Emerging Infectious Diseases</journal-title></journal-title-group><issn pub-type="ppub">1080-6040</issn><issn pub-type="epub">1080-6059</issn><publisher><publisher-name>Centers for Disease Control and Prevention</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">16485474</article-id><article-id pub-id-type="pmc">3367618</article-id><article-id pub-id-type="publisher-id">04-0949</article-id><article-id pub-id-type="doi">10.3201/eid1112.040949</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research</subject></subj-group></article-categories><title-group><article-title>Viral Load Distribution in SARS Outbreak</article-title><alt-title alt-title-type="running-head">Viral Load Distribution in SARS Outbreak</alt-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Chu</surname><given-names>Chung-Ming</given-names></name><xref ref-type="aff" rid="aff1">*</xref></contrib><contrib contrib-type="author"><name><surname>Cheng</surname><given-names>Vincent C.C.</given-names></name><xref ref-type="aff" rid="aff2">†</xref></contrib><contrib contrib-type="author"><name><surname>Hung</surname><given-names>Ivan F.N.</given-names></name><xref ref-type="aff" rid="aff2">†</xref></contrib><contrib contrib-type="author"><name><surname>Chan</surname><given-names>Kin-Sang</given-names></name><xref ref-type="aff" rid="aff1">*</xref></contrib><contrib contrib-type="author"><name><surname>Tang</surname><given-names>Bone S.F.</given-names></name><xref ref-type="aff" rid="aff2">†</xref></contrib><contrib contrib-type="author"><name><surname>Tsang</surname><given-names>Thomas H.F.</given-names></name><xref ref-type="aff" rid="aff3">‡</xref></contrib><contrib contrib-type="author"><name><surname>Chan</surname><given-names>Kwok-Hung</given-names></name><xref ref-type="aff" rid="aff2">†</xref></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Yuen</surname><given-names>Kwok-Yung</given-names></name><xref ref-type="aff" rid="aff2">†</xref></contrib><aff id="aff1"><label>*</label>United Christian Hospital, Hong Kong Special Administrative Region, People's Republic of China</aff><aff id="aff2"><label>†</label>University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China</aff><aff id="aff3"><label>‡</label>Department of Health, Hong Kong Special Administrative Region, People's Republic of China</aff></contrib-group><author-notes><corresp id="cor1">Address for correspondence: K.-Y. Yuen, Department of Microbiology, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong Special Administrative Region, People’s Republic of China; fax: 852-2855-1241; email: <email xlink:href="kyyuen@hkucc.hku.hk">kyyuen@hkucc.hku.hk</email></corresp></author-notes><pub-date pub-type="ppub"><month>12</month><year>2005</year></pub-date><volume>11</volume><issue>12</issue><fpage>1882</fpage><lpage>1886</lpage><abstract abstract-type="toc"><p>Airborne transmission may have resulted in an outbreak of SARS in Hong Kong.</p></abstract><abstract><p>An unprecedented community outbreak of severe acute respiratory syndrome (SARS) occurred in the Amoy Gardens, a high-rise residential complex in Hong Kong. Droplet, air, contaminated fomites, and rodent pests have been proposed to be mechanisms for transmitting SARS in a short period. We studied nasopharyngeal viral load of SARS patients on admission and their geographic distribution. Higher nasopharyngeal viral load was found in patients living in adjacent units of the same block inhabited by the index patient, while a lower but detectable nasopharyngeal viral load was found in patients living further away from the index patient. This pattern of nasopharyngeal viral load suggested that airborne transmission played an important part in this outbreak in Hong Kong. Contaminated fomites and rodent pests may have also played a role.</p></abstract><kwd-group kwd-group-type="author"><title>Keywords: </title><kwd>SARS</kwd><kwd>transmission</kwd><kwd>viral load</kwd><kwd>Amoy Gardens</kwd><kwd>research</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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