Expression of Lymphocytes and Lymphocyte Subsets in Patients with Severe Acute Respiratory Syndrome
Identifieur interne : 000839 ( Pmc/Curation ); précédent : 000838; suivant : 000840Expression of Lymphocytes and Lymphocyte Subsets in Patients with Severe Acute Respiratory Syndrome
Auteurs : Wei Cui ; Ying Fan ; Wei Wu ; Feng Zhang ; Jun-Ying Wang ; An-Ping NiSource :
- Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America [ 1058-4838 ] ; 2003.
Abstract
In a cohort of 38 patients with severe acute respiratory syndrome (SARS), we observed leukopenia in 47% of patients, lymphopenia in 84%, and T lymphopenia in 95%. CD4+ T lymphocyte levels were reduced in 100% of patients, CD8+ T lymphocyte levels were reduced in 87%, B lymphocyte levels were reduced in 76%, and natural killer cell levels were reduced in 55%. Our data suggested that these patients' immune systems were impaired during the course of SARS. The absolute counts of lymphocyte subsets demonstrated a clinical significance for patients with SARS.
Url:
DOI: 10.1086/378587
PubMed: 12955652
PubMed Central: 7110124
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000839
Links to Exploration step
PMC:7110124Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Expression of Lymphocytes and Lymphocyte Subsets in Patients with Severe Acute Respiratory Syndrome</title><author><name sortKey="Cui, Wei" sort="Cui, Wei" uniqKey="Cui W" first="Wei" last="Cui">Wei Cui</name><affiliation><nlm:aff id="d352119e128"></nlm:aff></affiliation></author><author><name sortKey="Fan, Ying" sort="Fan, Ying" uniqKey="Fan Y" first="Ying" last="Fan">Ying Fan</name><affiliation><nlm:aff id="d352119e128"></nlm:aff></affiliation></author><author><name sortKey="Wu, Wei" sort="Wu, Wei" uniqKey="Wu W" first="Wei" last="Wu">Wei Wu</name><affiliation><nlm:aff id="d352119e128"></nlm:aff></affiliation></author><author><name sortKey="Zhang, Feng" sort="Zhang, Feng" uniqKey="Zhang F" first="Feng" last="Zhang">Feng Zhang</name><affiliation><nlm:aff id="d352119e128"></nlm:aff></affiliation></author><author><name sortKey="Wang, Jun Ying" sort="Wang, Jun Ying" uniqKey="Wang J" first="Jun-Ying" last="Wang">Jun-Ying Wang</name><affiliation><nlm:aff id="d352119e128"></nlm:aff></affiliation></author><author><name sortKey="Ni, An Ping" sort="Ni, An Ping" uniqKey="Ni A" first="An-Ping" last="Ni">An-Ping Ni</name><affiliation><nlm:aff id="d352119e128"></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">12955652</idno><idno type="pmc">7110124</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110124</idno><idno type="RBID">PMC:7110124</idno><idno type="doi">10.1086/378587</idno><date when="2003">2003</date><idno type="wicri:Area/Pmc/Corpus">000839</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000839</idno><idno type="wicri:Area/Pmc/Curation">000839</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000839</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Expression of Lymphocytes and Lymphocyte Subsets in Patients with Severe Acute Respiratory Syndrome</title><author><name sortKey="Cui, Wei" sort="Cui, Wei" uniqKey="Cui W" first="Wei" last="Cui">Wei Cui</name><affiliation><nlm:aff id="d352119e128"></nlm:aff></affiliation></author><author><name sortKey="Fan, Ying" sort="Fan, Ying" uniqKey="Fan Y" first="Ying" last="Fan">Ying Fan</name><affiliation><nlm:aff id="d352119e128"></nlm:aff></affiliation></author><author><name sortKey="Wu, Wei" sort="Wu, Wei" uniqKey="Wu W" first="Wei" last="Wu">Wei Wu</name><affiliation><nlm:aff id="d352119e128"></nlm:aff></affiliation></author><author><name sortKey="Zhang, Feng" sort="Zhang, Feng" uniqKey="Zhang F" first="Feng" last="Zhang">Feng Zhang</name><affiliation><nlm:aff id="d352119e128"></nlm:aff></affiliation></author><author><name sortKey="Wang, Jun Ying" sort="Wang, Jun Ying" uniqKey="Wang J" first="Jun-Ying" last="Wang">Jun-Ying Wang</name><affiliation><nlm:aff id="d352119e128"></nlm:aff></affiliation></author><author><name sortKey="Ni, An Ping" sort="Ni, An Ping" uniqKey="Ni A" first="An-Ping" last="Ni">An-Ping Ni</name><affiliation><nlm:aff id="d352119e128"></nlm:aff></affiliation></author></analytic><series><title level="j">Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America</title><idno type="ISSN">1058-4838</idno><idno type="eISSN">1537-6591</idno><imprint><date when="2003">2003</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Abstract</title><p>In a cohort of 38 patients with severe acute respiratory syndrome (SARS), we observed leukopenia in 47% of patients, lymphopenia in 84%, and T lymphopenia in 95%. CD4<sup>+</sup> T lymphocyte levels were reduced in 100% of patients, CD8<sup>+</sup> T lymphocyte levels were reduced in 87%, B lymphocyte levels were reduced in 76%, and natural killer cell levels were reduced in 55%. Our data suggested that these patients' immune systems were impaired during the course of SARS. The absolute counts of lymphocyte subsets demonstrated a clinical significance for patients with SARS.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Benitez, Mn" uniqKey="Benitez M">MN Benitez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gerberding, Jl" uniqKey="Gerberding J">JL Gerberding</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Ksiazek, Tg" uniqKey="Ksiazek T">TG Ksiazek</name></author><author><name sortKey="Erdman, D" uniqKey="Erdman D">D Erdman</name></author><author><name sortKey="Goldsmith, Cs" uniqKey="Goldsmith C">CS Goldsmith</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Peiris, Jsm" uniqKey="Peiris J">JSM Peiris</name></author><author><name sortKey="Lai, St" uniqKey="Lai S">ST Lai</name></author><author><name sortKey="Poon, Llm" uniqKey="Poon L">LLM Poon</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Tsang, Kw" uniqKey="Tsang K">KW Tsang</name></author><author><name sortKey="Ho, Pk" uniqKey="Ho P">PK Ho</name></author><author><name sortKey="Ooi, Gc" uniqKey="Ooi G">GC Ooi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, N" uniqKey="Lee N">N Lee</name></author><author><name sortKey="Hui, D" uniqKey="Hui D">D Hui</name></author><author><name sortKey="Wu, A" uniqKey="Wu A">A Wu</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Veazey, R" uniqKey="Veazey R">R Veazey</name></author><author><name sortKey="Ling, B" uniqKey="Ling B">B Ling</name></author><author><name sortKey="Pandrea, I" uniqKey="Pandrea I">I Pandrea</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Dam, Jg" uniqKey="Van Dam J">JG Van Dam</name></author><author><name sortKey="Damoiseaux, Jg" uniqKey="Damoiseaux J">JG Damoiseaux</name></author><author><name sortKey="Christiaans, Mh" uniqKey="Christiaans M">MH Christiaans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dunne, Pj" uniqKey="Dunne P">PJ Dunne</name></author><author><name sortKey="Faint, Jm" uniqKey="Faint J">JM Faint</name></author><author><name sortKey="Gudgeon, Nh" uniqKey="Gudgeon N">NH Gudgeon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Welliver, Rc" uniqKey="Welliver R">RC Welliver</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="brief-report"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Clin Infect Dis</journal-id><journal-id journal-id-type="iso-abbrev">Clin. Infect. Dis</journal-id><journal-id journal-id-type="hwp">cid</journal-id><journal-id journal-id-type="publisher-id">cid</journal-id><journal-title-group><journal-title>Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America</journal-title></journal-title-group><issn pub-type="ppub">1058-4838</issn><issn pub-type="epub">1537-6591</issn><publisher><publisher-name>The University of Chicago Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">12955652</article-id><article-id pub-id-type="pmc">7110124</article-id><article-id pub-id-type="doi">10.1086/378587</article-id><article-categories><subj-group subj-group-type="heading"><subject>Brief Reports</subject></subj-group></article-categories><title-group><article-title>Expression of Lymphocytes and Lymphocyte Subsets in Patients with Severe Acute Respiratory Syndrome</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Cui</surname><given-names>Wei</given-names></name><xref ref-type="corresp" rid="cor1"></xref><xref ref-type="aff" rid="d352119e128"></xref><pmc-comment>mawx@csc.pumch.ac.cn </pmc-comment>
</contrib><contrib contrib-type="author"><name><surname>Fan</surname><given-names>Ying</given-names></name><xref ref-type="aff" rid="d352119e128"></xref></contrib><contrib contrib-type="author"><name><surname>Wu</surname><given-names>Wei</given-names></name><xref ref-type="aff" rid="d352119e128"></xref></contrib><contrib contrib-type="author"><name><surname>Zhang</surname><given-names>Feng</given-names></name><xref ref-type="aff" rid="d352119e128"></xref></contrib><contrib contrib-type="author"><name><surname>Wang</surname><given-names>Jun-ying</given-names></name><xref ref-type="aff" rid="d352119e128"></xref></contrib><contrib contrib-type="author"><name><surname>Ni</surname><given-names>An-ping</given-names></name><xref ref-type="aff" rid="d352119e128"></xref></contrib></contrib-group><aff id="d352119e128"><institution>Department of Clinical Laboratory, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences</institution>,<addr-line>Beijing, People's Republic of China</addr-line></aff><author-notes><corresp id="cor1">Reprints or correspondence: Dr. Wei Cui, Dept. of Clinical Laboratory, Peking Union Medical College Hospital, 1 Shuaifuyuan Wangfujing, Beijing, 100730, People's Republic of China (<email>mawx@csc.pumch.ac.cn</email>).</corresp></author-notes><pub-date pub-type="ppub"><day>15</day><month>9</month><year>2003</year></pub-date><pub-date pub-type="epub" iso-8601-date="2003-09-15"><day>15</day><month>9</month><year>2003</year></pub-date><pub-date pub-type="pmc-release"><day>15</day><month>9</month><year>2003</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on the
<volume>37</volume><issue>6</issue><fpage>857</fpage><lpage>859</lpage><history><date date-type="received"><day>1</day><month>6</month><year>2003</year></date><date date-type="accepted"><day>16</day><month>7</month><year>2003</year></date></history><permissions><copyright-statement>© 2003 by the Infectious Diseases Society of America</copyright-statement><copyright-year>2003</copyright-year><license><license-p>This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.</license-p></license></permissions><self-uri xlink:href="37-6-857.pdf"></self-uri><abstract><title>Abstract</title><p>In a cohort of 38 patients with severe acute respiratory syndrome (SARS), we observed leukopenia in 47% of patients, lymphopenia in 84%, and T lymphopenia in 95%. CD4<sup>+</sup> T lymphocyte levels were reduced in 100% of patients, CD8<sup>+</sup> T lymphocyte levels were reduced in 87%, B lymphocyte levels were reduced in 76%, and natural killer cell levels were reduced in 55%. Our data suggested that these patients' immune systems were impaired during the course of SARS. The absolute counts of lymphocyte subsets demonstrated a clinical significance for patients with SARS.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Pmc/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000839 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd -nk 000839 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= Pmc
|étape= Curation
|type= RBID
|clé= PMC:7110124
|texte= Expression of Lymphocytes and Lymphocyte Subsets in Patients with Severe Acute Respiratory Syndrome
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Curation/RBID.i -Sk "pubmed:12955652" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Curation/biblio.hfd \
| NlmPubMed2Wicri -a SrasV1
| This area was generated with Dilib version V0.6.33. |  |