CT features of SARS-CoV-2 pneumonia according to clinical presentation: a retrospective analysis of 120 consecutive patients from Wuhan city
Identifieur interne : 000375 ( Pmc/Curation ); précédent : 000374; suivant : 000376CT features of SARS-CoV-2 pneumonia according to clinical presentation: a retrospective analysis of 120 consecutive patients from Wuhan city
Auteurs : Rui Zhang [République populaire de Chine] ; Huangqing Ouyang [République populaire de Chine] ; Lingli Fu [République populaire de Chine] ; Shijie Wang [République populaire de Chine] ; Jianglong Han [République populaire de Chine] ; Kejie Huang [République populaire de Chine] ; Mingfang Jia [République populaire de Chine] ; Qibin Song [République populaire de Chine] ; Zhenming Fu [République populaire de Chine]Source :
- European Radiology [ 0938-7994 ] ; 2020.
Abstract
To characterize the chest computed tomography (CT) findings of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) according to clinical severity. We compared the CT features of common cases and severe cases, symptomatic patients and asymptomatic patients, and febrile and afebrile patients.
This was a retrospective analysis of the clinical and thoracic CT features of 120 consecutive patients with confirmed SARS-CoV-2 pneumonia admitted to a tertiary university hospital between January 10 and February 10, 2020, in Wuhan city, China.
On admission, the patients generally complained of fever, cough, shortness of breath, and myalgia or fatigue, with diarrhea often present in severe cases. Severe patients were 20 years older on average and had comorbidities and an elevated lactate dehydrogenase (LDH) level. There were no differences in the CT findings between asymptomatic and symptomatic common type patients or between afebrile and febrile patients, defined according to Chinese National Health Commission guidelines.
The clinical and CT features at admission may enable clinicians to promptly evaluate the prognosis of patients with SARS-CoV-2 pneumonia. Clinicians should be aware that clinically silent cases may present with CT features similar to those of symptomatic common patients.
The online version of this article (10.1007/s00330-020-06854-1) contains supplementary material, which is available to authorized users.
Url:
DOI: 10.1007/s00330-020-06854-1
PubMed: NONE
PubMed Central: 7150608
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University,</institution></institution-wrap>Wuhan, 430060 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Wuhan</wicri:regionArea></affiliation></author><author><name sortKey="Song, Qibin" sort="Song, Qibin" uniqKey="Song Q" first="Qibin" last="Song">Qibin Song</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.412632.0</institution-id><institution-id institution-id-type="ISNI">0000 0004 1758 2270</institution-id><institution>Cancer Center,</institution><institution>Renmin Hospital of Wuhan University,</institution></institution-wrap>Wuhan, 430060 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Wuhan</wicri:regionArea></affiliation></author><author><name sortKey="Fu, Zhenming" sort="Fu, Zhenming" uniqKey="Fu Z" first="Zhenming" last="Fu">Zhenming Fu</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="GRID">grid.412632.0</institution-id><institution-id institution-id-type="ISNI">0000 0004 1758 2270</institution-id><institution>Cancer Center,</institution><institution>Renmin Hospital of Wuhan University,</institution></institution-wrap>Wuhan, 430060 China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Wuhan</wicri:regionArea></affiliation></author></analytic><series><title level="j">European Radiology</title><idno type="ISSN">0938-7994</idno><idno type="eISSN">1432-1084</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Objectives</title><p id="Par1">To characterize the chest computed tomography (CT) findings of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) according to clinical severity. We compared the CT features of common cases and severe cases, symptomatic patients and asymptomatic patients, and febrile and afebrile patients.</p></sec><sec><title>Methods</title><p id="Par2">This was a retrospective analysis of the clinical and thoracic CT features of 120 consecutive patients with confirmed SARS-CoV-2 pneumonia admitted to a tertiary university hospital between January 10 and February 10, 2020, in Wuhan city, China.</p></sec><sec><title>Results</title><p id="Par3">On admission, the patients generally complained of fever, cough, shortness of breath, and myalgia or fatigue, with diarrhea often present in severe cases. Severe patients were 20 years older on average and had comorbidities and an elevated lactate dehydrogenase (LDH) level. There were no differences in the CT findings between asymptomatic and symptomatic common type patients or between afebrile and febrile patients, defined according to Chinese National Health Commission guidelines.</p></sec><sec><title>Conclusions</title><p id="Par4">The clinical and CT features at admission may enable clinicians to promptly evaluate the prognosis of patients with SARS-CoV-2 pneumonia. Clinicians should be aware that clinically silent cases may present with CT features similar to those of symptomatic common patients.</p></sec><sec><title>Key Points</title><p id="Par5"><italic>• The clinical features and predominant patterns of abnormalities on CT for asymptomatic, typic common, and severe cases were summarized. These findings may help clinicians to identify severe patients quickly at admission.</italic></p><p id="Par6"><italic>• Clinicians should be cautious that CT findings of afebrile/asymptomatic patients are not better than the findings of other types of patients. These patients should also be quarantined.</italic></p><p id="Par7"><italic>• The use of chest CT as the main screening method in epidemic areas is recommended.</italic></p></sec><sec><title>Electronic supplementary material</title><p>The online version of this article (10.1007/s00330-020-06854-1) contains supplementary material, which is available to authorized users.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Zhou, P" uniqKey="Zhou P">P Zhou</name></author><author><name sortKey="Yang, Xl" uniqKey="Yang X">XL Yang</name></author><author><name sortKey="Wang, Xg" uniqKey="Wang X">XG Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wong, Kt" uniqKey="Wong K">KT Wong</name></author><author><name sortKey="Antonio, Ge" uniqKey="Antonio G">GE Antonio</name></author><author><name sortKey="Hui, Ds" uniqKey="Hui D">DS Hui</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Paul, Ns" uniqKey="Paul N">NS Paul</name></author><author><name sortKey="Roberts, H" uniqKey="Roberts H">H Roberts</name></author><author><name sortKey="Butany, J" uniqKey="Butany J">J Butany</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Assiri, A" uniqKey="Assiri A">A Assiri</name></author><author><name sortKey="Al Tawfiq, Ja" uniqKey="Al Tawfiq J">JA Al-Tawfiq</name></author><author><name sortKey="Al Rabeeah, Aa" uniqKey="Al Rabeeah A">AA Al-Rabeeah</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Chen, N" uniqKey="Chen N">N Chen</name></author><author><name sortKey="Zhou, M" uniqKey="Zhou M">M Zhou</name></author><author><name sortKey="Dong, X" uniqKey="Dong X">X Dong</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Franquet, T" uniqKey="Franquet T">T Franquet</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Koo, Hj" uniqKey="Koo H">HJ Koo</name></author><author><name sortKey="Lim, S" uniqKey="Lim S">S Lim</name></author><author><name sortKey="Choe, J" uniqKey="Choe J">J Choe</name></author><author><name sortKey="Choi, Sh" uniqKey="Choi S">SH Choi</name></author><author><name sortKey="Sung, H" uniqKey="Sung H">H Sung</name></author><author><name sortKey="Do, Kh" uniqKey="Do K">KH Do</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Eur Radiol</journal-id><journal-id journal-id-type="iso-abbrev">Eur Radiol</journal-id><journal-title-group><journal-title>European Radiology</journal-title></journal-title-group><issn pub-type="ppub">0938-7994</issn><issn pub-type="epub">1432-1084</issn><publisher><publisher-name>Springer Berlin Heidelberg</publisher-name><publisher-loc>Berlin/Heidelberg</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmc">7150608</article-id><article-id pub-id-type="publisher-id">6854</article-id><article-id pub-id-type="doi">10.1007/s00330-020-06854-1</article-id><article-categories><subj-group subj-group-type="heading"><subject>Chest</subject></subj-group></article-categories><title-group><article-title>CT features of SARS-CoV-2 pneumonia according to clinical presentation: a retrospective analysis of 120 consecutive patients from Wuhan city</article-title></title-group><contrib-group><contrib contrib-type="author" equal-contrib="yes"><name><surname>Zhang</surname><given-names>Rui</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author" equal-contrib="yes"><name><surname>Ouyang</surname><given-names>Huangqing</given-names></name><xref ref-type="aff" rid="Aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Fu</surname><given-names>Lingli</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Wang</surname><given-names>Shijie</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Han</surname><given-names>Jianglong</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Huang</surname><given-names>Kejie</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Jia</surname><given-names>Mingfang</given-names></name><xref ref-type="aff" rid="Aff3">3</xref></contrib><contrib contrib-type="author"><name><surname>Song</surname><given-names>Qibin</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Fu</surname><given-names>Zhenming</given-names></name><address><email>davidfuzming@whu.edu.cn</email></address><xref ref-type="aff" rid="Aff1">1</xref></contrib><aff id="Aff1"><label>1</label><institution-wrap><institution-id institution-id-type="GRID">grid.412632.0</institution-id><institution-id institution-id-type="ISNI">0000 0004 1758 2270</institution-id><institution>Cancer Center,</institution><institution>Renmin Hospital of Wuhan University,</institution></institution-wrap>Wuhan, 430060 China</aff><aff id="Aff2"><label>2</label><institution-wrap><institution-id institution-id-type="GRID">grid.412632.0</institution-id><institution-id institution-id-type="ISNI">0000 0004 1758 2270</institution-id><institution>Department of Radiology,</institution><institution>Renmin Hospital of Wuhan University,</institution></institution-wrap>Wuhan, 430060 China</aff><aff id="Aff3"><label>3</label><institution-wrap><institution-id institution-id-type="GRID">grid.412632.0</institution-id><institution-id institution-id-type="ISNI">0000 0004 1758 2270</institution-id><institution>Department of Health Management,</institution><institution>Renmin Hospital of Wuhan University,</institution></institution-wrap>Wuhan, 430060 China</aff></contrib-group><pub-date pub-type="epub"><day>11</day><month>4</month><year>2020</year></pub-date><fpage>1</fpage><lpage>10</lpage><history><date date-type="received"><day>19</day><month>2</month><year>2020</year></date><date date-type="rev-recd"><day>19</day><month>3</month><year>2020</year></date><date date-type="accepted"><day>1</day><month>4</month><year>2020</year></date></history><permissions><copyright-statement>© European Society of Radiology 2020</copyright-statement><license><license-p>This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.</license-p></license></permissions><abstract id="Abs1"><sec><title>Objectives</title><p id="Par1">To characterize the chest computed tomography (CT) findings of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) according to clinical severity. We compared the CT features of common cases and severe cases, symptomatic patients and asymptomatic patients, and febrile and afebrile patients.</p></sec><sec><title>Methods</title><p id="Par2">This was a retrospective analysis of the clinical and thoracic CT features of 120 consecutive patients with confirmed SARS-CoV-2 pneumonia admitted to a tertiary university hospital between January 10 and February 10, 2020, in Wuhan city, China.</p></sec><sec><title>Results</title><p id="Par3">On admission, the patients generally complained of fever, cough, shortness of breath, and myalgia or fatigue, with diarrhea often present in severe cases. Severe patients were 20 years older on average and had comorbidities and an elevated lactate dehydrogenase (LDH) level. There were no differences in the CT findings between asymptomatic and symptomatic common type patients or between afebrile and febrile patients, defined according to Chinese National Health Commission guidelines.</p></sec><sec><title>Conclusions</title><p id="Par4">The clinical and CT features at admission may enable clinicians to promptly evaluate the prognosis of patients with SARS-CoV-2 pneumonia. Clinicians should be aware that clinically silent cases may present with CT features similar to those of symptomatic common patients.</p></sec><sec><title>Key Points</title><p id="Par5"><italic>• The clinical features and predominant patterns of abnormalities on CT for asymptomatic, typic common, and severe cases were summarized. These findings may help clinicians to identify severe patients quickly at admission.</italic></p><p id="Par6"><italic>• Clinicians should be cautious that CT findings of afebrile/asymptomatic patients are not better than the findings of other types of patients. These patients should also be quarantined.</italic></p><p id="Par7"><italic>• The use of chest CT as the main screening method in epidemic areas is recommended.</italic></p></sec><sec><title>Electronic supplementary material</title><p>The online version of this article (10.1007/s00330-020-06854-1) contains supplementary material, which is available to authorized users.</p></sec></abstract><kwd-group xml:lang="en"><title>Keywords</title><kwd>SARS-CoV-2</kwd><kwd>Tomography</kwd><kwd>Chest</kwd><kwd>Fever</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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