Effect of integrated traditional Chinese and Western medicine on SARS: A review of clinical evidence
Identifieur interne : 000008 ( Pmc/Curation ); précédent : 000007; suivant : 000009Effect of integrated traditional Chinese and Western medicine on SARS: A review of clinical evidence
Auteurs : Ming-Ming Zhang ; Xue-Mei Liu ; Lin HeSource :
- World Journal of Gastroenterology : WJG [ 1007-9327 ] ; 2004.
Abstract
AIM: To assess the possible effect of integrated traditional Chinese and Western medicine on severe acute respiratory syndromes.
METHODS: The current available randomized controlled trials of integrated traditional Chinese and Western medicine on SARS were identified through systematically searching literature in any languages or any types of publications. Additional studies of gray literature were also collected. The quality of studies was evaluated by two investigators independently based largely on the quality criteria specified CONSORT. Statistical analysis of the results was performed using RevMan 4.2.0 software developed by the Cochrane Collaboration.
RESULTS: Six studies (
CONCLUSION: Integrated traditional Chinese and Western medicines has some positive effects on lung infiltrate absorption in SARS patients, and is recommended as an adjunct treatment for SARS. However, its effect on SARS requires further careful study due to limited available randomized control trials.
Url:
DOI: 10.3748/wjg.v10.i23.3500
PubMed: 15526373
PubMed Central: 4576235
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<author><name sortKey="Zhang, Ming Ming" sort="Zhang, Ming Ming" uniqKey="Zhang M" first="Ming-Ming" last="Zhang">Ming-Ming Zhang</name>
</author>
<author><name sortKey="Liu, Xue Mei" sort="Liu, Xue Mei" uniqKey="Liu X" first="Xue-Mei" last="Liu">Xue-Mei Liu</name>
</author>
<author><name sortKey="He, Lin" sort="He, Lin" uniqKey="He L" first="Lin" last="He">Lin He</name>
</author>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Effect of integrated traditional Chinese and Western medicine on SARS: A review of clinical evidence</title>
<author><name sortKey="Zhang, Ming Ming" sort="Zhang, Ming Ming" uniqKey="Zhang M" first="Ming-Ming" last="Zhang">Ming-Ming Zhang</name>
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<author><name sortKey="Liu, Xue Mei" sort="Liu, Xue Mei" uniqKey="Liu X" first="Xue-Mei" last="Liu">Xue-Mei Liu</name>
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<author><name sortKey="He, Lin" sort="He, Lin" uniqKey="He L" first="Lin" last="He">Lin He</name>
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<series><title level="j">World Journal of Gastroenterology : WJG</title>
<idno type="ISSN">1007-9327</idno>
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<imprint><date when="2004">2004</date>
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<front><div type="abstract" xml:lang="en"><p>AIM: To assess the possible effect of integrated traditional Chinese and Western medicine on severe acute respiratory syndromes.</p>
<p>METHODS: The current available randomized controlled trials of integrated traditional Chinese and Western medicine on SARS were identified through systematically searching literature in any languages or any types of publications. Additional studies of gray literature were also collected. The quality of studies was evaluated by two investigators independently based largely on the quality criteria specified CONSORT. Statistical analysis of the results was performed using RevMan 4.2.0 software developed by the Cochrane Collaboration.</p>
<p>RESULTS: Six studies (<italic>n</italic>
= 366) fulfilling the inclusion criteria were found, of which the quality of one study was graded as B, the remaining five were graded as C. Two studies were performed with meta-analysis, the other four studies existed some heterogeneity for which meta-analysis could not be performed, a significant effect on lung infiltrate absorption was found in the treatment groups of these two studies [RR 6.68, 95%CI (2.93, 15.24), <italic>P</italic>
< 0.01], there was no significant differences between the mortality [RR 0.86, 95%CI (0.22, 3.29), <italic>P</italic>
= 0.82] and the average dosage of corticosteroid [WMD -39.65, 95%CI (-116.84, 37.54), <italic>P</italic>
= 0.31]. The other three studies also showed significant differences in infiltrate absorption, including national drug No. 2. 3. 4 in combination with Western medicine [RR 5.45, 95%CI (1.54, 19.26)], compound formulas NO. 1 combined with Western medicine [WMD 0.24, 95%CI (0.02, 0.46)], compound formulas combined with Western medicine [RR 8.06, 95%CI (0.40, 163.21)]. Kangfeidian No.4 in combination with Western medicine had no significant effect on symptom improvement such as loss of dyspnea and cough [RR 1.50, 95%CI (0.41, 5.43)] and [RR 1.29, 95%CI (0.30, 5.43)].</p>
<p>CONCLUSION: Integrated traditional Chinese and Western medicines has some positive effects on lung infiltrate absorption in SARS patients, and is recommended as an adjunct treatment for SARS. However, its effect on SARS requires further careful study due to limited available randomized control trials.</p>
</div>
</front>
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<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">World J Gastroenterol</journal-id>
<journal-id journal-id-type="iso-abbrev">World J. Gastroenterol</journal-id>
<journal-id journal-id-type="publisher-id">WJG</journal-id>
<journal-title-group><journal-title>World Journal of Gastroenterology : WJG</journal-title>
</journal-title-group>
<issn pub-type="ppub">1007-9327</issn>
<issn pub-type="epub">2219-2840</issn>
<publisher><publisher-name>Baishideng Publishing Group Inc</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">15526373</article-id>
<article-id pub-id-type="pmc">4576235</article-id>
<article-id pub-id-type="other">jWJG.v10.i23.pg3500</article-id>
<article-id pub-id-type="doi">10.3748/wjg.v10.i23.3500</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Clinical Research</subject>
</subj-group>
</article-categories>
<title-group><article-title>Effect of integrated traditional Chinese and Western medicine on SARS: A review of clinical evidence</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Zhang</surname>
<given-names>Ming-Ming</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Liu</surname>
<given-names>Xue-Mei</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>He</surname>
<given-names>Lin</given-names>
</name>
</contrib>
<aff>Ming-Ming Zhang, Chinese Evidence-Based Medicine Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China</aff>
<aff>Xue-Mei Liu, Editorial Department, Chinese Journal of Evidence-Based Medicine, Chinese Evidence-Based Medicine Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China</aff>
<aff>Lin He, Library of West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China</aff>
</contrib-group>
<author-notes><fn><p>Author contributions: All authors contributed equally to the work.</p>
<p>Correspondence to: Mrs. Xue-Mei Liu, Editorial Department, Chinese Journal of Evidence-Based Medicine, Chinese Evidence-Based Medicine Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China. <email>cochrane@mail.sc.cninfo.net</email>
</p>
<p>Telephone: +86-28-85422079 Fax: +86-28-85422253</p>
</fn>
</author-notes>
<pub-date pub-type="ppub"><day>1</day>
<month>12</month>
<year>2004</year>
</pub-date>
<pub-date pub-type="epub"><day>1</day>
<month>12</month>
<year>2004</year>
</pub-date>
<volume>10</volume>
<issue>23</issue>
<fpage>3500</fpage>
<lpage>3505</lpage>
<history><date date-type="received"><day>23</day>
<month>12</month>
<year>2003</year>
</date>
<date date-type="rev-recd"><day>22</day>
<month>1</month>
<year>2004</year>
</date>
<date date-type="accepted"><day>8</day>
<month>2</month>
<year>2004</year>
</date>
</history>
<permissions><copyright-statement>©The Author(s) 2004. Published by Baishideng Publishing Group Inc. All rights reserved.</copyright-statement>
<copyright-year>2004</copyright-year>
</permissions>
<abstract><p>AIM: To assess the possible effect of integrated traditional Chinese and Western medicine on severe acute respiratory syndromes.</p>
<p>METHODS: The current available randomized controlled trials of integrated traditional Chinese and Western medicine on SARS were identified through systematically searching literature in any languages or any types of publications. Additional studies of gray literature were also collected. The quality of studies was evaluated by two investigators independently based largely on the quality criteria specified CONSORT. Statistical analysis of the results was performed using RevMan 4.2.0 software developed by the Cochrane Collaboration.</p>
<p>RESULTS: Six studies (<italic>n</italic>
= 366) fulfilling the inclusion criteria were found, of which the quality of one study was graded as B, the remaining five were graded as C. Two studies were performed with meta-analysis, the other four studies existed some heterogeneity for which meta-analysis could not be performed, a significant effect on lung infiltrate absorption was found in the treatment groups of these two studies [RR 6.68, 95%CI (2.93, 15.24), <italic>P</italic>
< 0.01], there was no significant differences between the mortality [RR 0.86, 95%CI (0.22, 3.29), <italic>P</italic>
= 0.82] and the average dosage of corticosteroid [WMD -39.65, 95%CI (-116.84, 37.54), <italic>P</italic>
= 0.31]. The other three studies also showed significant differences in infiltrate absorption, including national drug No. 2. 3. 4 in combination with Western medicine [RR 5.45, 95%CI (1.54, 19.26)], compound formulas NO. 1 combined with Western medicine [WMD 0.24, 95%CI (0.02, 0.46)], compound formulas combined with Western medicine [RR 8.06, 95%CI (0.40, 163.21)]. Kangfeidian No.4 in combination with Western medicine had no significant effect on symptom improvement such as loss of dyspnea and cough [RR 1.50, 95%CI (0.41, 5.43)] and [RR 1.29, 95%CI (0.30, 5.43)].</p>
<p>CONCLUSION: Integrated traditional Chinese and Western medicines has some positive effects on lung infiltrate absorption in SARS patients, and is recommended as an adjunct treatment for SARS. However, its effect on SARS requires further careful study due to limited available randomized control trials.</p>
</abstract>
</article-meta>
</front>
</pmc>
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