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<title xml:lang="en">Coronavirus disease 2019 (COVID-19): A literature review</title>
<author>
<name sortKey="Harapan, Harapan" sort="Harapan, Harapan" uniqKey="Harapan H" first="Harapan" last="Harapan">Harapan Harapan</name>
<affiliation>
<nlm:aff id="aff0005">Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff0010">Tropical Disease Centre, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff0015">Department of Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Itoh, Naoya" sort="Itoh, Naoya" uniqKey="Itoh N" first="Naoya" last="Itoh">Naoya Itoh</name>
<affiliation>
<nlm:aff id="aff0020">Division of Infectious Diseases, Shizuoka Cancer Center Hospital, Sunto-gun, Japan</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Yufika, Amanda" sort="Yufika, Amanda" uniqKey="Yufika A" first="Amanda" last="Yufika">Amanda Yufika</name>
<affiliation>
<nlm:aff id="aff0025">Department of Family Medicine, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Winardi, Wira" sort="Winardi, Wira" uniqKey="Winardi W" first="Wira" last="Winardi">Wira Winardi</name>
<affiliation>
<nlm:aff id="aff0030">Department of Pulmonology and Respiratory Medicine, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Keam, Synat" sort="Keam, Synat" uniqKey="Keam S" first="Synat" last="Keam">Synat Keam</name>
<affiliation>
<nlm:aff id="aff0035">School of Medicine, The University of Western Australia, Perth, Australia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Te, Heyhpeng" sort="Te, Heyhpeng" uniqKey="Te H" first="Heyhpeng" last="Te">Heyhpeng Te</name>
<affiliation>
<nlm:aff id="aff0040">Siem Reap Provincial Health Department, Ministry of Health, Siem Reap, Cambodia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Megawati, Dewi" sort="Megawati, Dewi" uniqKey="Megawati D" first="Dewi" last="Megawati">Dewi Megawati</name>
<affiliation>
<nlm:aff id="aff0045">Department of Microbiology, Faculty of Medicine and Health Sciences, Warmadewa University, Denpasar, Indonesia</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff0050">Department of Medical Microbiology and Immunology, University of California, Davis, California, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Hayati, Zinatul" sort="Hayati, Zinatul" uniqKey="Hayati Z" first="Zinatul" last="Hayati">Zinatul Hayati</name>
<affiliation>
<nlm:aff id="aff0005">Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff0010">Tropical Disease Centre, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff0015">Department of Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff0055">Department of Clinical Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Wagner, Abram L" sort="Wagner, Abram L" uniqKey="Wagner A" first="Abram L." last="Wagner">Abram L. Wagner</name>
<affiliation>
<nlm:aff id="aff0060">Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, MI 48109, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Mudatsir, Mudatsir" sort="Mudatsir, Mudatsir" uniqKey="Mudatsir M" first="Mudatsir" last="Mudatsir">Mudatsir Mudatsir</name>
<affiliation>
<nlm:aff id="aff0005">Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff0010">Tropical Disease Centre, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff0015">Department of Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
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<idno type="pmc">7142680</idno>
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<idno type="RBID">PMC:7142680</idno>
<idno type="doi">10.1016/j.jiph.2020.03.019</idno>
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<date when="2020">2020</date>
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<title xml:lang="en" level="a" type="main">Coronavirus disease 2019 (COVID-19): A literature review</title>
<author>
<name sortKey="Harapan, Harapan" sort="Harapan, Harapan" uniqKey="Harapan H" first="Harapan" last="Harapan">Harapan Harapan</name>
<affiliation>
<nlm:aff id="aff0005">Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff0010">Tropical Disease Centre, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff0015">Department of Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Itoh, Naoya" sort="Itoh, Naoya" uniqKey="Itoh N" first="Naoya" last="Itoh">Naoya Itoh</name>
<affiliation>
<nlm:aff id="aff0020">Division of Infectious Diseases, Shizuoka Cancer Center Hospital, Sunto-gun, Japan</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Yufika, Amanda" sort="Yufika, Amanda" uniqKey="Yufika A" first="Amanda" last="Yufika">Amanda Yufika</name>
<affiliation>
<nlm:aff id="aff0025">Department of Family Medicine, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Winardi, Wira" sort="Winardi, Wira" uniqKey="Winardi W" first="Wira" last="Winardi">Wira Winardi</name>
<affiliation>
<nlm:aff id="aff0030">Department of Pulmonology and Respiratory Medicine, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Keam, Synat" sort="Keam, Synat" uniqKey="Keam S" first="Synat" last="Keam">Synat Keam</name>
<affiliation>
<nlm:aff id="aff0035">School of Medicine, The University of Western Australia, Perth, Australia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Te, Heyhpeng" sort="Te, Heyhpeng" uniqKey="Te H" first="Heyhpeng" last="Te">Heyhpeng Te</name>
<affiliation>
<nlm:aff id="aff0040">Siem Reap Provincial Health Department, Ministry of Health, Siem Reap, Cambodia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Megawati, Dewi" sort="Megawati, Dewi" uniqKey="Megawati D" first="Dewi" last="Megawati">Dewi Megawati</name>
<affiliation>
<nlm:aff id="aff0045">Department of Microbiology, Faculty of Medicine and Health Sciences, Warmadewa University, Denpasar, Indonesia</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff0050">Department of Medical Microbiology and Immunology, University of California, Davis, California, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Hayati, Zinatul" sort="Hayati, Zinatul" uniqKey="Hayati Z" first="Zinatul" last="Hayati">Zinatul Hayati</name>
<affiliation>
<nlm:aff id="aff0005">Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff0010">Tropical Disease Centre, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff0015">Department of Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff0055">Department of Clinical Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Wagner, Abram L" sort="Wagner, Abram L" uniqKey="Wagner A" first="Abram L." last="Wagner">Abram L. Wagner</name>
<affiliation>
<nlm:aff id="aff0060">Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, MI 48109, USA</nlm:aff>
</affiliation>
</author>
<author>
<name sortKey="Mudatsir, Mudatsir" sort="Mudatsir, Mudatsir" uniqKey="Mudatsir M" first="Mudatsir" last="Mudatsir">Mudatsir Mudatsir</name>
<affiliation>
<nlm:aff id="aff0005">Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff0010">Tropical Disease Centre, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
<affiliation>
<nlm:aff id="aff0015">Department of Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</nlm:aff>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Journal of Infection and Public Health</title>
<idno type="ISSN">1876-0341</idno>
<idno type="eISSN">1876-035X</idno>
<imprint>
<date when="2020">2020</date>
</imprint>
</series>
</biblStruct>
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<textClass></textClass>
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</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<p>In early December 2019, an outbreak of coronavirus disease 2019 (COVID-19), caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), occurred in Wuhan City, Hubei Province, China. On January 30, 2020 the World Health Organization declared the outbreak as a Public Health Emergency of International Concern. As of February 14, 2020, 49,053 laboratory-confirmed and 1,381 deaths have been reported globally. Perceived risk of acquiring disease has led many governments to institute a variety of control measures. We conducted a literature review of publicly available information to summarize knowledge about the pathogen and the current epidemic. In this literature review, the causative agent, pathogenesis and immune responses, epidemiology, diagnosis, treatment and management of the disease, control and preventions strategies are all reviewed.</p>
</div>
</front>
</TEI>
<pmc article-type="review-article">
<pmc-dir>properties open_access</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">J Infect Public Health</journal-id>
<journal-id journal-id-type="iso-abbrev">J Infect Public Health</journal-id>
<journal-title-group>
<journal-title>Journal of Infection and Public Health</journal-title>
</journal-title-group>
<issn pub-type="ppub">1876-0341</issn>
<issn pub-type="epub">1876-035X</issn>
<publisher>
<publisher-name>The Authors. Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences.</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmc">7142680</article-id>
<article-id pub-id-type="publisher-id">S1876-0341(20)30432-9</article-id>
<article-id pub-id-type="doi">10.1016/j.jiph.2020.03.019</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Coronavirus disease 2019 (COVID-19): A literature review</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" id="aut0005">
<name>
<surname>Harapan</surname>
<given-names>Harapan</given-names>
</name>
<email>harapan@unsyiah.ac.id</email>
<xref rid="aff0005" ref-type="aff">a</xref>
<xref rid="aff0010" ref-type="aff">b</xref>
<xref rid="aff0015" ref-type="aff">c</xref>
<xref rid="cor0005" ref-type="corresp"></xref>
</contrib>
<contrib contrib-type="author" id="aut0010">
<name>
<surname>Itoh</surname>
<given-names>Naoya</given-names>
</name>
<email>itohnaoya0925@ybb.ne.jp</email>
<xref rid="aff0020" ref-type="aff">d</xref>
</contrib>
<contrib contrib-type="author" id="aut0015">
<name>
<surname>Yufika</surname>
<given-names>Amanda</given-names>
</name>
<email>amandayufika@gmail.com</email>
<xref rid="aff0025" ref-type="aff">e</xref>
</contrib>
<contrib contrib-type="author" id="aut0020">
<name>
<surname>Winardi</surname>
<given-names>Wira</given-names>
</name>
<email>winardi.wira@gmail.com</email>
<xref rid="aff0030" ref-type="aff">f</xref>
</contrib>
<contrib contrib-type="author" id="aut0025">
<name>
<surname>Keam</surname>
<given-names>Synat</given-names>
</name>
<email>synat.keam@research.uwa.edu.au</email>
<xref rid="aff0035" ref-type="aff">g</xref>
</contrib>
<contrib contrib-type="author" id="aut0030">
<name>
<surname>Te</surname>
<given-names>Heyhpeng</given-names>
</name>
<email>hayphengte@gmail.com</email>
<xref rid="aff0040" ref-type="aff">h</xref>
</contrib>
<contrib contrib-type="author" id="aut0035">
<name>
<surname>Megawati</surname>
<given-names>Dewi</given-names>
</name>
<email>amegawati@ucdavis.edu</email>
<xref rid="aff0045" ref-type="aff">i</xref>
<xref rid="aff0050" ref-type="aff">j</xref>
</contrib>
<contrib contrib-type="author" id="aut0040">
<name>
<surname>Hayati</surname>
<given-names>Zinatul</given-names>
</name>
<email>hayatikarmil@gmail.com</email>
<xref rid="aff0005" ref-type="aff">a</xref>
<xref rid="aff0010" ref-type="aff">b</xref>
<xref rid="aff0015" ref-type="aff">c</xref>
<xref rid="aff0055" ref-type="aff">k</xref>
</contrib>
<contrib contrib-type="author" id="aut0045">
<name>
<surname>Wagner</surname>
<given-names>Abram L.</given-names>
</name>
<email>awag@umich.edu</email>
<xref rid="aff0060" ref-type="aff">l</xref>
</contrib>
<contrib contrib-type="author" id="aut0050">
<name>
<surname>Mudatsir</surname>
<given-names>Mudatsir</given-names>
</name>
<email>mudatsir@unsyiah.ac.id</email>
<xref rid="aff0005" ref-type="aff">a</xref>
<xref rid="aff0010" ref-type="aff">b</xref>
<xref rid="aff0015" ref-type="aff">c</xref>
</contrib>
</contrib-group>
<aff id="aff0005">
<label>a</label>
Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</aff>
<aff id="aff0010">
<label>b</label>
Tropical Disease Centre, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</aff>
<aff id="aff0015">
<label>c</label>
Department of Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</aff>
<aff id="aff0020">
<label>d</label>
Division of Infectious Diseases, Shizuoka Cancer Center Hospital, Sunto-gun, Japan</aff>
<aff id="aff0025">
<label>e</label>
Department of Family Medicine, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</aff>
<aff id="aff0030">
<label>f</label>
Department of Pulmonology and Respiratory Medicine, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</aff>
<aff id="aff0035">
<label>g</label>
School of Medicine, The University of Western Australia, Perth, Australia</aff>
<aff id="aff0040">
<label>h</label>
Siem Reap Provincial Health Department, Ministry of Health, Siem Reap, Cambodia</aff>
<aff id="aff0045">
<label>i</label>
Department of Microbiology, Faculty of Medicine and Health Sciences, Warmadewa University, Denpasar, Indonesia</aff>
<aff id="aff0050">
<label>j</label>
Department of Medical Microbiology and Immunology, University of California, Davis, California, USA</aff>
<aff id="aff0055">
<label>k</label>
Department of Clinical Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia</aff>
<aff id="aff0060">
<label>l</label>
Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, MI 48109, USA</aff>
<author-notes>
<corresp id="cor0005">
<label></label>
Corresponding author. Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Jl. T. Tanoeh Abe, Darussalam, Banda Aceh 23111, Indonesia, Tel./fax: +62 (0) 651 7551843.
<email>harapan@unsyiah.ac.id</email>
</corresp>
</author-notes>
<pub-date pub-type="pmc-release">
<day>8</day>
<month>4</month>
<year>2020</year>
</pub-date>
<pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="epub">
<day>8</day>
<month>4</month>
<year>2020</year>
</pub-date>
<history>
<date date-type="received">
<day>6</day>
<month>3</month>
<year>2020</year>
</date>
<date date-type="accepted">
<day>29</day>
<month>3</month>
<year>2020</year>
</date>
</history>
<permissions>
<copyright-statement>© 2020 The Authors. Published by Elsevier Ltd on behalf of King Saud Bin Abdulaziz University for Health Sciences.</copyright-statement>
<copyright-year>2020</copyright-year>
<copyright-holder></copyright-holder>
<license>
<license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p>
</license>
</permissions>
<abstract id="abs0005">
<p>In early December 2019, an outbreak of coronavirus disease 2019 (COVID-19), caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), occurred in Wuhan City, Hubei Province, China. On January 30, 2020 the World Health Organization declared the outbreak as a Public Health Emergency of International Concern. As of February 14, 2020, 49,053 laboratory-confirmed and 1,381 deaths have been reported globally. Perceived risk of acquiring disease has led many governments to institute a variety of control measures. We conducted a literature review of publicly available information to summarize knowledge about the pathogen and the current epidemic. In this literature review, the causative agent, pathogenesis and immune responses, epidemiology, diagnosis, treatment and management of the disease, control and preventions strategies are all reviewed.</p>
</abstract>
<kwd-group id="kwd0005">
<title>Keywords</title>
<kwd>2019-nCoV</kwd>
<kwd>COVID-19</kwd>
<kwd>Outbreak</kwd>
<kwd>SARS-CoV-2</kwd>
<kwd>Novel coronavirus</kwd>
</kwd-group>
</article-meta>
</front>
</pmc>
</record>

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