Bayesian Analysis of Severe Acute Respiratory Syndrome: The 2003 Hong Kong Epidemic
Identifieur interne : 000E40 ( Pmc/Corpus ); précédent : 000E39; suivant : 000E41Bayesian Analysis of Severe Acute Respiratory Syndrome: The 2003 Hong Kong Epidemic
Auteurs : Phenyo E. LekoneSource :
- Biometrical Journal. Biometrische Zeitschrift [ 0323-3847 ] ; 2008.
Abstract
This paper analyzes data arising from a Severe Acute Respiratory Syndrome (SARS) epidemic in Hong Kong in 2003 involving 1755 cases. A discrete time stochastic model that uses a back‐projection approach is proposed. Markov Chain Monte Carlo (MCMC) methods are developed for estimation of model parameters. The algorithm is further extended to integrate numerically over unobserved variables of the model. Applying the method to SARS data from Hong Kong, a value of 3.88 with a posterior standard deviation of 0.09 was estimated for the basic reproduction number. An estimate of the transmission parameter at the beginning of the epidemic was also obtained as 0.149 with a posterior standard deviation of 0.003. A reduction in the transmission parameter during the course of the epidemic forced the effective reproduction number to cross the threshold value of one, seven days after control interventions were introduced. At the end of the epidemic, the effective reproduction number was as low as 0.001 suggesting that the epidemic was brought under control by the intervention measures introduced. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Url:
DOI: 10.1002/bimj.200710431
PubMed: 18615412
PubMed Central: 7161832
Links to Exploration step
PMC:7161832Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Bayesian Analysis of Severe Acute Respiratory Syndrome: The 2003 Hong Kong Epidemic</title><author><name sortKey="Lekone, Phenyo E" sort="Lekone, Phenyo E" uniqKey="Lekone P" first="Phenyo E." last="Lekone">Phenyo E. Lekone</name><affiliation><nlm:aff id="a1"></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">18615412</idno><idno type="pmc">7161832</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161832</idno><idno type="RBID">PMC:7161832</idno><idno type="doi">10.1002/bimj.200710431</idno><date when="2008">2008</date><idno type="wicri:Area/Pmc/Corpus">000E40</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000E40</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Bayesian Analysis of Severe Acute Respiratory Syndrome: The 2003 Hong Kong Epidemic</title><author><name sortKey="Lekone, Phenyo E" sort="Lekone, Phenyo E" uniqKey="Lekone P" first="Phenyo E." last="Lekone">Phenyo E. Lekone</name><affiliation><nlm:aff id="a1"></nlm:aff></affiliation></author></analytic><series><title level="j">Biometrical Journal. Biometrische Zeitschrift</title><idno type="ISSN">0323-3847</idno><idno type="eISSN">1521-4036</idno><imprint><date when="2008">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Abstract</title><p>This paper analyzes data arising from a Severe Acute Respiratory Syndrome (SARS) epidemic in Hong Kong in 2003 involving 1755 cases. A discrete time stochastic model that uses a back‐projection approach is proposed. Markov Chain Monte Carlo (MCMC) methods are developed for estimation of model parameters. The algorithm is further extended to integrate numerically over unobserved variables of the model. Applying the method to SARS data from Hong Kong, a value of 3.88 with a posterior standard deviation of 0.09 was estimated for the basic reproduction number. An estimate of the transmission parameter at the beginning of the epidemic was also obtained as 0.149 with a posterior standard deviation of 0.003. A reduction in the transmission parameter during the course of the epidemic forced the effective reproduction number to cross the threshold value of one, seven days after control interventions were introduced. At the end of the epidemic, the effective reproduction number was as low as 0.001 suggesting that the epidemic was brought under control by the intervention measures introduced. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Biom J</journal-id><journal-id journal-id-type="iso-abbrev">Biom J</journal-id><journal-id journal-id-type="doi">10.1002/(ISSN)1521-4036</journal-id><journal-id journal-id-type="publisher-id">BIMJ</journal-id><journal-title-group><journal-title>Biometrical Journal. Biometrische Zeitschrift</journal-title></journal-title-group><issn pub-type="ppub">0323-3847</issn><issn pub-type="epub">1521-4036</issn><publisher><publisher-name>WILEY‐VCH Verlag</publisher-name><publisher-loc>Weinheim</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">18615412</article-id><article-id pub-id-type="pmc">7161832</article-id><article-id pub-id-type="doi">10.1002/bimj.200710431</article-id><article-id pub-id-type="publisher-id">BIMJ200710431</article-id><article-categories><subj-group subj-group-type="overline"><subject>Statistical Methods in Epidemiology</subject></subj-group><subj-group subj-group-type="heading"><subject>Statistical Methods in Epidemiology</subject></subj-group></article-categories><title-group><article-title>Bayesian Analysis of Severe Acute Respiratory Syndrome: The 2003 Hong Kong Epidemic</article-title><alt-title alt-title-type="right-running-head">Bayesian Analysis of the 2003 SARS Epidermic</alt-title></title-group><contrib-group><contrib id="au1" contrib-type="author" corresp="yes"><name><surname>Lekone</surname><given-names>Phenyo E.</given-names></name><xref ref-type="aff" rid="a1"><sup>1</sup></xref><address><email>lekonepe@mopipi.ub.bw</email></address></contrib></contrib-group><aff id="a1"><label><sup>1</sup></label>Mathematics Department, University of Botswana, Private Bag 0022, Gaborone, Botswana</aff><author-notes><corresp id="correspondenceTo"><label>*</label>Phone: +00267 355 2127, Fax: +00267 355 2784</corresp></author-notes><pub-date pub-type="epub"><day>09</day><month>7</month><year>2008</year></pub-date><pub-date pub-type="ppub"><month>8</month><year>2008</year></pub-date><volume>50</volume><issue>4</issue><issue-id pub-id-type="doi">10.1002/bimj.v50:4</issue-id><fpage>597</fpage><lpage>607</lpage><history><date date-type="received"><day>30</day><month>10</month><year>2007</year></date><date date-type="rev-recd"><day>03</day><month>3</month><year>2008</year></date><date date-type="accepted"><day>19</day><month>3</month><year>2008</year></date></history><permissions><copyright-statement content-type="article-copyright">Copyright © 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim</copyright-statement><license><license-p>This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.</license-p></license></permissions><self-uri content-type="pdf" xlink:href="file:BIMJ-50-597.pdf"></self-uri><abstract><title>Abstract</title><p>This paper analyzes data arising from a Severe Acute Respiratory Syndrome (SARS) epidemic in Hong Kong in 2003 involving 1755 cases. A discrete time stochastic model that uses a back‐projection approach is proposed. Markov Chain Monte Carlo (MCMC) methods are developed for estimation of model parameters. The algorithm is further extended to integrate numerically over unobserved variables of the model. Applying the method to SARS data from Hong Kong, a value of 3.88 with a posterior standard deviation of 0.09 was estimated for the basic reproduction number. An estimate of the transmission parameter at the beginning of the epidemic was also obtained as 0.149 with a posterior standard deviation of 0.003. A reduction in the transmission parameter during the course of the epidemic forced the effective reproduction number to cross the threshold value of one, seven days after control interventions were introduced. At the end of the epidemic, the effective reproduction number was as low as 0.001 suggesting that the epidemic was brought under control by the intervention measures introduced. (© 2008 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)</p></abstract><kwd-group kwd-group-type="author-generated"><kwd id="kwd1">Back‐projection</kwd><kwd id="kwd2">Bayesian inference</kwd><kwd id="kwd3">Control Intervention</kwd><kwd id="kwd4">SARS epidemics</kwd></kwd-group><funding-group><award-group id="funding-0001"><funding-source>University of Warwick</funding-source></award-group><award-group id="funding-0002"><funding-source>United Kingdom's national Overseas Research Scheme (ORS)</funding-source></award-group><award-group id="funding-0003"><funding-source>University of Botswana</funding-source></award-group></funding-group><counts><fig-count count="5"></fig-count><table-count count="2"></table-count><ref-count count="18"></ref-count><page-count count="11"></page-count></counts><custom-meta-group><custom-meta><meta-name>source-schema-version-number</meta-name><meta-value>2.0</meta-value></custom-meta><custom-meta><meta-name>cover-date</meta-name><meta-value>August 2008</meta-value></custom-meta><custom-meta><meta-name>details-of-publishers-convertor</meta-name><meta-value>Converter:WILEY_ML3GV2_TO_JATSPMC version:5.8.0 mode:remove_FC converted:15.04.2020</meta-value></custom-meta></custom-meta-group></article-meta></front><back><ref-list><title>References</title><ref id="bib1"><mixed-citation publication-type="journal" id="cit1"><string-name><surname>Becker</surname>, <given-names>N. G.</given-names></string-name>, <string-name><surname>Watson</surname>, <given-names>L. F.</given-names></string-name>, and <string-name><surname>Carlin</surname>, <given-names>J. B.</given-names></string-name> (<year>1991</year>). <article-title>A method of non‐parametric back‐projection and its application to AIDS data</article-title>. <source xml:lang="en">Statistics in Medicine</source><volume>10</volume>, <fpage>1527</fpage>–<lpage>1542</lpage>.
<pub-id pub-id-type="pmid">1947509</pub-id></mixed-citation></ref><ref id="bib2"><mixed-citation publication-type="journal" id="cit2"><string-name><surname>Becker</surname>, <given-names>N. G.</given-names></string-name> and <string-name><surname>Xu</surname>, <given-names>C.</given-names></string-name> (<year>1994</year>). <article-title>Dependent HIV incidences in back‐projection of AIDS incidence data</article-title>. <source xml:lang="en">Statistics in Medicine</source><volume>13</volume>, <fpage>1945</fpage>–<lpage>1958</lpage>.
<pub-id pub-id-type="pmid">7846402</pub-id></mixed-citation></ref><ref id="bib3"><mixed-citation publication-type="journal" id="cit3"><string-name><surname>Brookmeyer</surname>, <given-names>R.</given-names></string-name> and <string-name><surname>Gail</surname>, <given-names>M. H.</given-names></string-name> (<year>1986</year>). <article-title>Minimum size of the acquired immunodeficiency syndrome (AIDS) epidemic in the United States</article-title>. <source xml:lang="en">Lancet</source><volume>2</volume>, <fpage>1320</fpage>–<lpage>1322</lpage>.
<pub-id pub-id-type="pmid">2878184</pub-id></mixed-citation></ref><ref id="bib4"><mixed-citation publication-type="journal" id="cit4"><string-name><surname>Chau</surname>, <given-names>P. H.</given-names></string-name> and <string-name><surname>Yip</surname>, <given-names>P. S. F.</given-names></string-name> (<year>2003a</year>). <article-title>Monitoring the severe acute respiratory syndrome epidemic and assessing effectiveness of interventions in Hong Kong Special Administrative Region</article-title>. <source xml:lang="en">Journal of Epidemiology and Community Health</source><volume>57</volume>, <fpage>766</fpage>–<lpage>769</lpage>.
<pub-id pub-id-type="pmid">14573569</pub-id></mixed-citation></ref><ref id="bib5"><mixed-citation publication-type="journal" id="cit5"><string-name><surname>Chau</surname>, <given-names>P. H.</given-names></string-name> and <string-name><surname>Yip</surname>, <given-names>P. S. F.</given-names></string-name> (<year>2003b</year>). <article-title>Modelling the severe acute respiratory syndrome</article-title>. <source xml:lang="en">Hong Kong Medical Journal</source><volume>9</volume>, <fpage>310</fpage>–<lpage>311</lpage>.
</mixed-citation></ref><ref id="bib6"><mixed-citation publication-type="journal" id="cit6"><string-name><surname>Chib</surname>, <given-names>S.</given-names></string-name> and <string-name><surname>Jeliazkov</surname>, <given-names>I.</given-names></string-name> (<year>2001</year>). <article-title>Marginal likelihood from the Metropolis‐Hastings output</article-title>. <source xml:lang="en">Journal of the American Statistical Association</source><volume>96</volume>, <fpage>270</fpage>–<lpage>281</lpage>.
</mixed-citation></ref><ref id="bib7"><mixed-citation publication-type="journal" id="cit7"><string-name><surname>Chowell</surname>, <given-names>G.</given-names></string-name>, <string-name><surname>Fenimore</surname>, <given-names>P. W.</given-names></string-name>, <string-name><surname>Castillo‐Garsow</surname>, <given-names>M. A.</given-names></string-name>, and <string-name><surname>Castillo‐Chavez</surname>, <given-names>C.</given-names></string-name> (<year>2003</year>). <article-title>SARS outbreaks in Ontario, Hong Kong and Singapore: the role of diagnosis and isolation as a control mechanism</article-title>. <source xml:lang="en">Journal of Theoretical Biology</source><volume>224</volume>, <fpage>1</fpage>–<lpage>8</lpage>.
<pub-id pub-id-type="pmid">12900200</pub-id></mixed-citation></ref><ref id="bib8"><mixed-citation publication-type="journal" id="cit8"><string-name><surname>Chowell</surname>, <given-names>G.</given-names></string-name>, <string-name><surname>Hengartner</surname>, <given-names>N. W.</given-names></string-name>, <string-name><surname>Castillo‐Chavez</surname>, <given-names>C.</given-names></string-name>, <string-name><surname>Fenimore</surname>, <given-names>P. W.</given-names></string-name>, and <string-name><surname>Hyman</surname>, <given-names>J. M.</given-names></string-name> (<year>2004</year>). <article-title>The basic reproductive number of Ebola and the effects of public health measures: The cases of Congo and Uganda</article-title>. <source xml:lang="en">Journal of Theoretical Biology</source><volume>229</volume>, <fpage>119</fpage>–<lpage>126</lpage>.
<pub-id pub-id-type="pmid">15178190</pub-id></mixed-citation></ref><ref id="bib9"><mixed-citation publication-type="journal" id="cit9"><string-name><surname>Diekmann</surname>, <given-names>O.</given-names></string-name>, <string-name><surname>Heesterbeek</surname>, <given-names>J. A.</given-names></string-name>, and <string-name><surname>Metz</surname>, <given-names>J. A.</given-names></string-name> (<year>1990</year>). <article-title>On the definition and the computation of the basic reproduction ratio <italic>R</italic><sub>0</sub> in models for infectious diseases in heterogeneous populations</article-title>. <source xml:lang="en">Journal of Mathematical Biology</source><volume>28</volume>, <fpage>365</fpage>–<lpage>382</lpage>.
<pub-id pub-id-type="pmid">2117040</pub-id></mixed-citation></ref><ref id="bib10"><mixed-citation publication-type="journal" id="cit10"><string-name><surname>Donnelly</surname>, <given-names>C. A.</given-names></string-name>, <string-name><surname>Ghani</surname>, <given-names>A. C.</given-names></string-name>, <string-name><surname>Leung</surname>, <given-names>G. M.</given-names></string-name>, <string-name><surname>Hedley</surname>, <given-names>A. J.</given-names></string-name>, <string-name><surname>Fraser</surname>, <given-names>C.</given-names></string-name>, <string-name><surname>Riley</surname>, <given-names>S.</given-names></string-name>, <string-name><surname>Abu‐Raddad</surname>, <given-names>L. J.</given-names></string-name>, <string-name><surname>Ho</surname>, <given-names>L.</given-names></string-name>, <string-name><surname>Thach</surname>, <given-names>T.</given-names></string-name>, <string-name><surname>Chau</surname>, <given-names>P.</given-names></string-name>, <string-name><surname>Chan</surname>, <given-names>K.</given-names></string-name>, <string-name><surname>Lam</surname>, <given-names>T.</given-names></string-name>, <string-name><surname>Tse</surname>, <given-names>L.</given-names></string-name>, <string-name><surname>Tsang</surname>, <given-names>T.</given-names></string-name>, <string-name><surname>Liu</surname>, <given-names>S.</given-names></string-name>, <string-name><surname>Kong</surname>, <given-names>J. H. B.</given-names></string-name>, <string-name><surname>Lau</surname>, <given-names>E. M. C.</given-names></string-name>, <string-name><surname>Ferguson</surname>, <given-names>N. M.</given-names></string-name>, and <string-name><surname>Anderson</surname>, <given-names>R. M.</given-names></string-name> (<year>2003</year>). <article-title>Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong</article-title>. <source xml:lang="en">The Lancet</source><volume>361</volume>, <fpage>1761</fpage>–<lpage>1766</lpage>.
</mixed-citation></ref><ref id="bib11"><mixed-citation publication-type="miscellaneous" id="cit11"><string-name><surname>Doornik</surname>, <given-names>J. A.</given-names></string-name> (<year>1999</year>). <article-title><italic>Object‐orientated Matrix Programming using Ox version 2.1.</italic> Timberlake Consultants Limited, London.</article-title></mixed-citation></ref><ref id="bib12"><mixed-citation publication-type="journal" id="cit12"><string-name><surname>Gelman</surname>, <given-names>A.</given-names></string-name>, <string-name><surname>Meng</surname>, <given-names>X. L.</given-names></string-name>, and <string-name><surname>Stern</surname>, <given-names>H.</given-names></string-name> (<year>1996</year>). <article-title>Posterior predictive assessment of model fitness via realized discrepancies</article-title>. <source xml:lang="en">Statistica Sinica</source><volume>6</volume>, <fpage>733</fpage>–<lpage>807</lpage>.
</mixed-citation></ref><ref id="bib13"><mixed-citation publication-type="journal" id="cit13"><string-name><surname>Lekone</surname>, <given-names>P. E.</given-names></string-name> and <string-name><surname>Finkenstädt</surname>, <given-names>B. F.</given-names></string-name> (<year>2006</year>). <article-title>Statistical inference in a stochastic epidemic SEIR model with control intervention: Ebola as a case study</article-title>. <source xml:lang="en">Biometrics</source><volume>62</volume>, <fpage>1170</fpage>–<lpage>1177</lpage>.
<pub-id pub-id-type="pmid">17156292</pub-id></mixed-citation></ref><ref id="bib14"><mixed-citation publication-type="journal" id="cit14"><string-name><surname>Leung</surname>, <given-names>G. M.</given-names></string-name>, <string-name><surname>Hedley</surname>, <given-names>A. J.</given-names></string-name>, <string-name><surname>Ho</surname>, <given-names>L.</given-names></string-name>, <string-name><surname>Chau</surname>, <given-names>P.</given-names></string-name>, <string-name><surname>Wong</surname>, <given-names>I. O. L.</given-names></string-name>, <string-name><surname>Thach</surname>, <given-names>T. Q.</given-names></string-name>, <string-name><surname>Ghani</surname>, <given-names>A. C.</given-names></string-name>, <string-name><surname>Donnelly</surname>, <given-names>C. A.</given-names></string-name>, <string-name><surname>Fraser</surname>, <given-names>C.</given-names></string-name>, <string-name><surname>Riley</surname>, <given-names>S.</given-names></string-name>, <string-name><surname>Ferguson</surname>, <given-names>N. M.</given-names></string-name>, <string-name><surname>Anderson</surname>, <given-names>R. M.</given-names></string-name>, <string-name><surname>Tsang</surname>, <given-names>T.</given-names></string-name>, <string-name><surname>Leung</surname>, <given-names>P.</given-names></string-name>, <string-name><surname>Wong</surname>, <given-names>V.</given-names></string-name>, <string-name><surname>Chan</surname>, <given-names>J. C. K.</given-names></string-name>, <string-name><surname>Tsui</surname>, <given-names>E.</given-names></string-name>, <string-name><surname>Lo</surname>, <given-names>S.</given-names></string-name>, and <string-name><surname>Lam</surname>, <given-names>T.</given-names></string-name> (<year>2004</year>). <article-title>The epidemiology of severe acute respiratory syndrome in the 2003 Hong Kong epidemic: an analysis of all 1755 patients</article-title>. <source xml:lang="en">Annals of Internal Medicine</source><volume>141</volume>, <fpage>662</fpage>–<lpage>673</lpage>.
<pub-id pub-id-type="pmid">15520422</pub-id></mixed-citation></ref><ref id="bib15"><mixed-citation publication-type="journal" id="cit15"><string-name><surname>Lipsitch</surname>, <given-names>M.</given-names></string-name>, <string-name><surname>Cohen</surname>, <given-names>T.</given-names></string-name>, <string-name><surname>Cooper</surname>, <given-names>B.</given-names></string-name>, <string-name><surname>Robins</surname>, <given-names>J. M.</given-names></string-name>, <string-name><surname>Ma</surname>, <given-names>S.</given-names></string-name>, <string-name><surname>James</surname>, <given-names>L.</given-names></string-name>, <string-name><surname>Gopalakrishma</surname>, <given-names>G.</given-names></string-name>, <string-name><surname>Chew</surname>, <given-names>S. K.</given-names></string-name>, <string-name><surname>Tan</surname>, <given-names>C. C.</given-names></string-name>, <string-name><surname>Samore</surname>, <given-names>M. H.</given-names></string-name>, <string-name><surname>Fisman</surname>, <given-names>D.</given-names></string-name>, and <string-name><surname>Murray</surname>, <given-names>M.</given-names></string-name> (<year>2003</year>). <article-title>Transmission dynamics and control of severe acute respiratory syndrome</article-title>. <source xml:lang="en">Science</source><volume>300</volume>, <fpage>1966</fpage>–<lpage>1970</lpage>.
<pub-id pub-id-type="pmid">12766207</pub-id></mixed-citation></ref><ref id="bib16"><mixed-citation publication-type="journal" id="cit16"><string-name><surname>McBryde</surname>, <given-names>E. S.</given-names></string-name>, <string-name><surname>Gibson</surname>, <given-names>G.</given-names></string-name>, <string-name><surname>Pettitt</surname>, <given-names>A. N.</given-names></string-name>, <string-name><surname>Zhang</surname>, <given-names>Y.</given-names></string-name>, <string-name><surname>Zhao</surname>, <given-names>B.</given-names></string-name>, and <string-name><surname>McElwain</surname>, <given-names>D. L. S.</given-names></string-name> (<year>2006</year>). <article-title>Bayesian modelling of an epidemic of severe acute respiratory syndrome</article-title>. <source xml:lang="en">Bulletin of Mathematical Biology</source><volume>68</volume>, <fpage>889</fpage>–<lpage>917</lpage>.
<pub-id pub-id-type="pmid">16802088</pub-id></mixed-citation></ref><ref id="bib17"><mixed-citation publication-type="journal" id="cit17"><string-name><surname>Riley</surname>, <given-names>S.</given-names></string-name>, <string-name><surname>Fraser</surname>, <given-names>C.</given-names></string-name>, <string-name><surname>Donnelly</surname>, <given-names>C. A.</given-names></string-name>, <string-name><surname>Ghani</surname>, <given-names>A. C.</given-names></string-name>, <string-name><surname>Abbu‐Raddad</surname>, <given-names>L. J.</given-names></string-name>, <string-name><surname>Hedley</surname>, <given-names>A. J.</given-names></string-name>, <string-name><surname>Leung</surname>, <given-names>G. M.</given-names></string-name>, <string-name><surname>Ho</surname>, <given-names>L.</given-names></string-name>, <string-name><surname>Lam</surname>, <given-names>T.</given-names></string-name>, <string-name><surname>Thach</surname>, <given-names>T. Q.</given-names></string-name>, <string-name><surname>Chau</surname>, <given-names>P.</given-names></string-name>, <string-name><surname>Chan</surname>, <given-names>K.</given-names></string-name>, <string-name><surname>Lo</surname>, <given-names>S.</given-names></string-name>, <string-name><surname>Leung</surname>, <given-names>P.</given-names></string-name>, <string-name><surname>Tsang</surname>, <given-names>T.</given-names></string-name>, <string-name><surname>Ho</surname>, <given-names>W.</given-names></string-name>, <string-name><surname>Lee</surname>, <given-names>K.</given-names></string-name>, <string-name><surname>Lau</surname>, <given-names>E. M. C.</given-names></string-name>, and <string-name><surname>Ferguson</surname>, <given-names>N. M.</given-names></string-name> (<year>2003</year>). <article-title>Transmission dynamics of the aetiological agent of severe acute respiratory syndrome (SARS) in Hong Kong: the impact of public health interventions</article-title>. <source xml:lang="en">Science</source><volume>300</volume>, <fpage>1961</fpage>–<lpage>1966</lpage>.
<pub-id pub-id-type="pmid">12766206</pub-id></mixed-citation></ref><ref id="bib18"><mixed-citation publication-type="journal" id="cit18"><string-name><surname>Wallinga</surname>, <given-names>J.</given-names></string-name> and <string-name><surname>Teunis</surname>, <given-names>P.</given-names></string-name> (<year>2004</year>). <article-title>Different epidemic curves for severe acute respiratory syndrome reveal similar impacts of control measures</article-title>. <source xml:lang="en">American Journal of Epidemiology</source><volume>160</volume>, <fpage>509</fpage>–<lpage>516</lpage>.
<pub-id pub-id-type="pmid">15353409</pub-id></mixed-citation></ref></ref-list></back></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000E40 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 000E40 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= Pmc
|étape= Corpus
|type= RBID
|clé= PMC:7161832
|texte= Bayesian Analysis of Severe Acute Respiratory Syndrome: The 2003 Hong Kong Epidemic
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/RBID.i -Sk "pubmed:18615412" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a SrasV1
| This area was generated with Dilib version V0.6.33. |  |