SARS case was influenza H5N1
Identifieur interne : 000B74 ( Pmc/Corpus ); précédent : 000B73; suivant : 000B75SARS case was influenza H5N1
Auteurs : Khabir AhmadSource :
- The Lancet. Infectious Diseases [ 1473-3099 ] ; 2006.
Url:
DOI: 10.1016/S1473-3099(06)70538-2
PubMed: NONE
PubMed Central: 7128650
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">SARS case was influenza H5N1</title><author><name sortKey="Ahmad, Khabir" sort="Ahmad, Khabir" uniqKey="Ahmad K" first="Khabir" last="Ahmad">Khabir Ahmad</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmc">7128650</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7128650</idno><idno type="RBID">PMC:7128650</idno><idno type="doi">10.1016/S1473-3099(06)70538-2</idno><idno type="pmid">NONE</idno><date when="2006">2006</date><idno type="wicri:Area/Pmc/Corpus">000B74</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000B74</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">SARS case was influenza H5N1</title><author><name sortKey="Ahmad, Khabir" sort="Ahmad, Khabir" uniqKey="Ahmad K" first="Khabir" last="Ahmad">Khabir Ahmad</name></author></analytic><series><title level="j">The Lancet. Infectious Diseases</title><idno type="ISSN">1473-3099</idno><idno type="eISSN">1474-4457</idno><imprint><date when="2006">2006</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader></TEI><pmc article-type="other"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Lancet Infect Dis</journal-id><journal-id journal-id-type="iso-abbrev">Lancet Infect Dis</journal-id><journal-title-group><journal-title>The Lancet. Infectious Diseases</journal-title></journal-title-group><issn pub-type="ppub">1473-3099</issn><issn pub-type="epub">1474-4457</issn><publisher><publisher-name>Published by Elsevier Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmc">7128650</article-id><article-id pub-id-type="publisher-id">S1473-3099(06)70538-2</article-id><article-id pub-id-type="doi">10.1016/S1473-3099(06)70538-2</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>SARS case was influenza H5N1</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Ahmad</surname><given-names>Khabir</given-names></name></contrib></contrib-group><pub-date pub-type="pmc-release"><day>24</day><month>7</month><year>2006</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><month>8</month><year>2006</year></pub-date><pub-date pub-type="epub"><day>24</day><month>7</month><year>2006</year></pub-date><volume>6</volume><issue>8</issue><fpage>470</fpage><lpage>470</lpage><permissions><copyright-statement>© 2006 </copyright-statement><copyright-year>2006</copyright-year><license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p></license></permissions></article-meta></front><body><p id="para10">China's Ministry of Health is doing tests to confirm <ext-link ext-link-type="doi" xlink:href="10.1056/NEJMc066058">a report that a patient</ext-link> who reportedly died of severe acute respiratory syndrome (SARS) in China in Nov, 2003, in fact died of an H5N1 infection. “The Ministry of Health has not yet reported if it has reached a conclusion”, says Roy Wadia (WHO China).</p><p id="para20">According to WHO China, human H5N1 cases were reported first in Hong Kong in 1997 and early 2003—and it would not be surprising if the virus was in the environment on the mainland for several years before that.</p><p id="para30">Qing-Yu Zhu (State Key Laboratory of Pathogens and Biosecurity, Beijing, China) and colleagues reported that a young man died of pneumonia and respiratory distress 4 days after he was hospitalised. He had tested negative for SARS, but was labelled as a sporadic case because his symptoms were consistent with SARS and his death occurred when southern China was experiencing sporadic cases of SARS. Isolation of a virus from his lung tissue, and its subsequent genomic sequencing and comparison with influenza A viral strains from China and other countries, revealed that the 24-year-old had an influenza A (H5N1) infection.</p><p id="para40">The authors noted that these findings have important implications for vaccine development: “The genetic distance between the isolate reported and the strain currently proposed for vaccine development…implies that viruses from different regions may need to be considered in the development of an effective vaccine against influenza A virus.”</p><p id="para50">China's Ministry of Health maintains that it was unaware of this potential case, but clarified that parallel laboratory tests were underway, as required under WHO and Chinese diagnostic standards for H5N1. On the eve of the publication, <italic>The New England Journal of Medicine</italic> received “multiple” letters demanding its retraction, says Karen Pedersen, the journal's spokesperson. “One of the emails was bearing the email address of the corresponding author, but when we contacted him he said he and his colleagues stood by their findings.”</p><p id="para60">Several H5N1 experts declined to comment on the report because they said it was too political. John Treanor (University of Rochester, NY, USA) believes that the report expands our understanding of the history of the epidemic. “It certainly suggests that other cases in humans could have occurred that were not recognised, particularly in the background of the concurrent SARS epidemic, as clinically differentiating SARS and avian influenza must be extremely difficult if not impossible”, he concluded.</p></body></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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