Exercise Limitation in Survivors of Severe Acute Respiratory Syndrome (SARS)
Identifieur interne : 000771 ( Pmc/Corpus ); précédent : 000770; suivant : 000772Exercise Limitation in Survivors of Severe Acute Respiratory Syndrome (SARS)
Auteurs : Veronica L. Chan ; Judy Y. Lam ; Wah-Shing Leung ; Alsa W. Lin ; Chung-Ming ChuSource :
- Chest [ 0012-3692 ] ; 2004.
Url:
DOI: 10.1378/chest.126.4_MeetingAbstracts.737S
PubMed: NONE
PubMed Central: 7130167
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Exercise Limitation in Survivors of Severe Acute Respiratory Syndrome (SARS)</title><author><name sortKey="Chan, Veronica L" sort="Chan, Veronica L" uniqKey="Chan V" first="Veronica L." last="Chan">Veronica L. Chan</name></author><author><name sortKey="Lam, Judy Y" sort="Lam, Judy Y" uniqKey="Lam J" first="Judy Y." last="Lam">Judy Y. Lam</name></author><author><name sortKey="Leung, Wah Shing" sort="Leung, Wah Shing" uniqKey="Leung W" first="Wah-Shing" last="Leung">Wah-Shing Leung</name></author><author><name sortKey="Lin, Alsa W" sort="Lin, Alsa W" uniqKey="Lin A" first="Alsa W." last="Lin">Alsa W. Lin</name></author><author><name sortKey="Chu, Chung Ming" sort="Chu, Chung Ming" uniqKey="Chu C" first="Chung-Ming" last="Chu">Chung-Ming Chu</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmc">7130167</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7130167</idno><idno type="RBID">PMC:7130167</idno><idno type="doi">10.1378/chest.126.4_MeetingAbstracts.737S</idno><idno type="pmid">NONE</idno><date when="2004">2004</date><idno type="wicri:Area/Pmc/Corpus">000771</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000771</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Exercise Limitation in Survivors of Severe Acute Respiratory Syndrome (SARS)</title><author><name sortKey="Chan, Veronica L" sort="Chan, Veronica L" uniqKey="Chan V" first="Veronica L." last="Chan">Veronica L. Chan</name></author><author><name sortKey="Lam, Judy Y" sort="Lam, Judy Y" uniqKey="Lam J" first="Judy Y." last="Lam">Judy Y. Lam</name></author><author><name sortKey="Leung, Wah Shing" sort="Leung, Wah Shing" uniqKey="Leung W" first="Wah-Shing" last="Leung">Wah-Shing Leung</name></author><author><name sortKey="Lin, Alsa W" sort="Lin, Alsa W" uniqKey="Lin A" first="Alsa W." last="Lin">Alsa W. Lin</name></author><author><name sortKey="Chu, Chung Ming" sort="Chu, Chung Ming" uniqKey="Chu C" first="Chung-Ming" last="Chu">Chung-Ming Chu</name></author></analytic><series><title level="j">Chest</title><idno type="ISSN">0012-3692</idno><idno type="eISSN">1931-3543</idno><imprint><date when="2004">2004</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader></TEI><pmc article-type="abstract"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Chest</journal-id><journal-id journal-id-type="iso-abbrev">Chest</journal-id><journal-title-group><journal-title>Chest</journal-title></journal-title-group><issn pub-type="ppub">0012-3692</issn><issn pub-type="epub">1931-3543</issn><publisher><publisher-name>The American College of Chest Physicians. Published by Elsevier Inc.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmc">7130167</article-id><article-id pub-id-type="publisher-id">S0012-3692(16)46461-5</article-id><article-id pub-id-type="doi">10.1378/chest.126.4_MeetingAbstracts.737S</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Exercise Limitation in Survivors of Severe Acute Respiratory Syndrome (SARS)</article-title></title-group><contrib-group><contrib contrib-type="author" id="au10"><name><surname>Chan</surname><given-names>Veronica L.</given-names></name><degrees>MBChB*</degrees></contrib><contrib contrib-type="author" id="au20"><name><surname>Lam</surname><given-names>Judy Y.</given-names></name><degrees>MBBS</degrees></contrib><contrib contrib-type="author" id="au30"><name><surname>Leung</surname><given-names>Wah-Shing</given-names></name><degrees>MBChB</degrees></contrib><contrib contrib-type="author" id="au40"><name><surname>Lin</surname><given-names>Alsa W.</given-names></name><degrees>RN</degrees></contrib><contrib contrib-type="author" id="au50"><name><surname>Chu</surname><given-names>Chung-Ming</given-names></name><degrees>FCCP</degrees></contrib></contrib-group><aff id="aff1">United Christian Hospital, Kowloon, Hong Kong PRC</aff><pub-date pub-type="pmc-release"><day>29</day><month>3</month><year>2016</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><month>10</month><year>2004</year></pub-date><pub-date pub-type="epub"><day>29</day><month>3</month><year>2016</year></pub-date><volume>126</volume><issue>4</issue><fpage>737S</fpage><lpage>737S</lpage><permissions><copyright-statement>© 2004 The American College of Chest Physicians</copyright-statement><copyright-year>2004</copyright-year><license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p></license></permissions></article-meta></front><body><sec id="cesec10"><title>Abstract</title><p id="para10"><bold>PURPOSE:</bold> Severe acute respiratory syndrome (SARS) is a newly recognized viral pneumonia caused by a novel coronavirus (SARS-CoV). In the acute stage, it is often complicated by diffuse alveolar damage and respiratory failure. Survivors often report exercise limitation, which is poorly characterized. We aim to study the cardiopulmonary response to exercise in a group of SARS survivors.</p><p id="para20"><bold>METHODS:</bold> Symptom-limited cardiopulmonary exercise testing (CPET) according to the American Thoracic Society guideline was performed in a group of SARS survivors 6 months after discharge. Peak oxygen consumption (VO2max) and the patho-physiologic mechanisms of exercise limitation were determined.</p><p id="para30"><bold>RESULTS:</bold> We studied 16 patients (3 male, 13 female, mean age 36.2 ± 8.7 years) who contracted SARS during the epidemic in 2003. They all reported exercise limitation after discharge. At 6 months after discharge, the mean VO2max was 27.2 ± 6.0 ml/kg/min (88.4 ± 13.5% predicted). Four patients (25%) had normal CPET. Of the remaining 12 patients, 7 (43.8%) had reduced work capacity due to deconditioning, 3 (18.8%) had cardiac limitation of exercise (2 had ischemic changes on exercise ECG and 1 had cardiac arrhythmia during exercise), 1 (6.3%) had ventilatory limitation of exercise, and 1 (6.3%) had steroid-induced myopathy. Three patients (18.8%) also had exercise-induced oxygen desaturation (>4%) as an additional limiting factor to exercise, with a mean nadir Sa02 of 93.3 ± 1.2%.</p><p id="para40"><bold>CONCLUSION:</bold> In SARS survivors who reported exercise limitation, a variety of patho-physiologic mechanisms were revealed on CPET at 6 months.</p><p id="para50"><bold>CLINICAL IMPLICATIONS:</bold> This finding is relevant to disability assessment and rehabilitation in these patients. More studies on exercise physiology in SARS survivors are warranted.</p><p id="para60"><bold>DISCLOSURE:</bold> V.L. Chan, None.</p><p id="para70">Tuesday, October 26, 2004</p><p id="para80">10:30 AM- 12:00 PM</p></sec></body></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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