Evaluating the virucidal efficacy of hydrogen peroxide vapour
Identifieur interne : 000899 ( Pmc/Checkpoint ); précédent : 000898; suivant : 000900Evaluating the virucidal efficacy of hydrogen peroxide vapour
Auteurs : S. M. Goyal [États-Unis] ; Y. Chander [États-Unis] ; S. Yezli [Royaume-Uni] ; J. A. Otter [Royaume-Uni]Source :
- The Journal of Hospital Infection [ 0195-6701 ] ; 2014.
Abstract
Surface contamination has been implicated in the transmission of certain viruses, and surface disinfection can be an effective measure to interrupt the spread of these agents.
To evaluate the in-vitro efficacy of hydrogen peroxide vapour (HPV), a vapour-phase disinfection method, for the inactivation of a number of structurally distinct viruses of importance in the healthcare, veterinary and public sectors. The viruses studied were: feline calicivirus (FCV, a norovirus surrogate); human adenovirus type 1; transmissible gastroenteritis coronavirus of pigs (TGEV, a severe acute respiratory syndrome coronavirus [SARS-CoV] surrogate); avian influenza virus (AIV); and swine influenza virus (SwIV).
The viruses were dried on stainless steel discs in 20- or 40-μL aliquots and exposed to HPV produced by a Clarus L generator (Bioquell, Horsham, PA, USA) in a 0.2-m3 environmental chamber. Three vaporized volumes of hydrogen peroxide were tested in triplicate for each virus: 25, 27 and 33 mL.
No viable viruses were identified after HPV exposure at any of the vaporized volumes tested. HPV was virucidal (>4-log reduction) against FCV, adenovirus, TGEV and AIV at the lowest vaporized volume tested (25 mL). For SwIV, due to low virus titre on the control discs, >3.8-log reduction was shown for the 25-mL vaporized volume and >4-log reduction was shown for the 27-mL and 33-mL vaporized volumes.
HPV was virucidal for structurally distinct viruses dried on surfaces, suggesting that HPV can be considered for the disinfection of virus-contaminated surfaces.
Url:
DOI: 10.1016/j.jhin.2014.02.003
PubMed: 24656442
PubMed Central: 7132520
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Evaluating the virucidal efficacy of hydrogen peroxide vapour</title><author><name sortKey="Goyal, S M" sort="Goyal, S M" uniqKey="Goyal S" first="S. M." last="Goyal">S. M. Goyal</name><affiliation wicri:level="2"><nlm:aff id="aff1">Department of Veterinary Population Medicine, University of Minnesota, Saint Paul, MN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veterinary Population Medicine, University of Minnesota, Saint Paul, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Chander, Y" sort="Chander, Y" uniqKey="Chander Y" first="Y." last="Chander">Y. Chander</name><affiliation wicri:level="2"><nlm:aff id="aff1">Department of Veterinary Population Medicine, University of Minnesota, Saint Paul, MN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veterinary Population Medicine, University of Minnesota, Saint Paul, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Yezli, S" sort="Yezli, S" uniqKey="Yezli S" first="S." last="Yezli">S. Yezli</name><affiliation wicri:level="1"><nlm:aff id="aff2">Bioquell UK Ltd, Andover, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Bioquell UK Ltd, Andover</wicri:regionArea><wicri:noRegion>Andover</wicri:noRegion></affiliation></author><author><name sortKey="Otter, J A" sort="Otter, J A" uniqKey="Otter J" first="J. A." last="Otter">J. A. Otter</name><affiliation wicri:level="1"><nlm:aff id="aff2">Bioquell UK Ltd, Andover, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Bioquell UK Ltd, Andover</wicri:regionArea><wicri:noRegion>Andover</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3">Centre for Clinical Infection and Diagnostics Research (CIDR), Department of Infectious Diseases, King's College London School of Medicine and Guy’s and St Thomas’ NHS Foundation Trust, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Clinical Infection and Diagnostics Research (CIDR), Department of Infectious Diseases, King's College London School of Medicine and Guy’s and St Thomas’ NHS Foundation Trust</wicri:regionArea><wicri:noRegion>King's College London School of Medicine and Guy’s and St Thomas’ NHS Foundation Trust</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24656442</idno><idno type="pmc">7132520</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132520</idno><idno type="RBID">PMC:7132520</idno><idno type="doi">10.1016/j.jhin.2014.02.003</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">001150</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001150</idno><idno type="wicri:Area/Pmc/Curation">001150</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001150</idno><idno type="wicri:Area/Pmc/Checkpoint">000899</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000899</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Evaluating the virucidal efficacy of hydrogen peroxide vapour</title><author><name sortKey="Goyal, S M" sort="Goyal, S M" uniqKey="Goyal S" first="S. M." last="Goyal">S. M. Goyal</name><affiliation wicri:level="2"><nlm:aff id="aff1">Department of Veterinary Population Medicine, University of Minnesota, Saint Paul, MN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veterinary Population Medicine, University of Minnesota, Saint Paul, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Chander, Y" sort="Chander, Y" uniqKey="Chander Y" first="Y." last="Chander">Y. Chander</name><affiliation wicri:level="2"><nlm:aff id="aff1">Department of Veterinary Population Medicine, University of Minnesota, Saint Paul, MN, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Veterinary Population Medicine, University of Minnesota, Saint Paul, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Yezli, S" sort="Yezli, S" uniqKey="Yezli S" first="S." last="Yezli">S. Yezli</name><affiliation wicri:level="1"><nlm:aff id="aff2">Bioquell UK Ltd, Andover, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Bioquell UK Ltd, Andover</wicri:regionArea><wicri:noRegion>Andover</wicri:noRegion></affiliation></author><author><name sortKey="Otter, J A" sort="Otter, J A" uniqKey="Otter J" first="J. A." last="Otter">J. A. Otter</name><affiliation wicri:level="1"><nlm:aff id="aff2">Bioquell UK Ltd, Andover, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Bioquell UK Ltd, Andover</wicri:regionArea><wicri:noRegion>Andover</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3">Centre for Clinical Infection and Diagnostics Research (CIDR), Department of Infectious Diseases, King's College London School of Medicine and Guy’s and St Thomas’ NHS Foundation Trust, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Centre for Clinical Infection and Diagnostics Research (CIDR), Department of Infectious Diseases, King's College London School of Medicine and Guy’s and St Thomas’ NHS Foundation Trust</wicri:regionArea><wicri:noRegion>King's College London School of Medicine and Guy’s and St Thomas’ NHS Foundation Trust</wicri:noRegion></affiliation></author></analytic><series><title level="j">The Journal of Hospital Infection</title><idno type="ISSN">0195-6701</idno><idno type="eISSN">1532-2939</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Summary</title><sec><title>Background</title><p>Surface contamination has been implicated in the transmission of certain viruses, and surface disinfection can be an effective measure to interrupt the spread of these agents.</p></sec><sec><title>Aim</title><p>To evaluate the in-vitro efficacy of hydrogen peroxide vapour (HPV), a vapour-phase disinfection method, for the inactivation of a number of structurally distinct viruses of importance in the healthcare, veterinary and public sectors. The viruses studied were: feline calicivirus (FCV, a norovirus surrogate); human adenovirus type 1; transmissible gastroenteritis coronavirus of pigs (TGEV, a severe acute respiratory syndrome coronavirus [SARS-CoV] surrogate); avian influenza virus (AIV); and swine influenza virus (SwIV).</p></sec><sec><title>Methods</title><p>The viruses were dried on stainless steel discs in 20- or 40-μL aliquots and exposed to HPV produced by a Clarus L generator (Bioquell, Horsham, PA, USA) in a 0.2-m<sup>3</sup> environmental chamber. Three vaporized volumes of hydrogen peroxide were tested in triplicate for each virus: 25, 27 and 33 mL.</p></sec><sec><title>Findings</title><p>No viable viruses were identified after HPV exposure at any of the vaporized volumes tested. HPV was virucidal (>4-log reduction) against FCV, adenovirus, TGEV and AIV at the lowest vaporized volume tested (25 mL). For SwIV, due to low virus titre on the control discs, >3.8-log reduction was shown for the 25-mL vaporized volume and >4-log reduction was shown for the 27-mL and 33-mL vaporized volumes.</p></sec><sec><title>Conclusion</title><p>HPV was virucidal for structurally distinct viruses dried on surfaces, suggesting that HPV can be considered for the disinfection of virus-contaminated surfaces.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Otter, J A" uniqKey="Otter J">J.A. Otter</name></author><author><name sortKey="Yezli, S" uniqKey="Yezli S">S. Yezli</name></author><author><name sortKey="French, G L" uniqKey="French G">G.L. French</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yezli, S" uniqKey="Yezli S">S. Yezli</name></author><author><name sortKey="Otter, J A" uniqKey="Otter J">J.A. 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Brown</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Hosp Infect</journal-id><journal-id journal-id-type="iso-abbrev">J. Hosp. Infect</journal-id><journal-title-group><journal-title>The Journal of Hospital Infection</journal-title></journal-title-group><issn pub-type="ppub">0195-6701</issn><issn pub-type="epub">1532-2939</issn><publisher><publisher-name>The Healthcare Infection Society. Published by Elsevier Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">24656442</article-id><article-id pub-id-type="pmc">7132520</article-id><article-id pub-id-type="publisher-id">S0195-6701(14)00059-0</article-id><article-id pub-id-type="doi">10.1016/j.jhin.2014.02.003</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Evaluating the virucidal efficacy of hydrogen peroxide vapour</article-title></title-group><contrib-group><contrib contrib-type="author" id="au1"><name><surname>Goyal</surname><given-names>S.M.</given-names></name><email>goyal001@umn.edu</email><xref rid="aff1" ref-type="aff">a</xref><xref rid="cor1" ref-type="corresp">∗</xref></contrib><contrib contrib-type="author" id="au2"><name><surname>Chander</surname><given-names>Y.</given-names></name><xref rid="aff1" ref-type="aff">a</xref></contrib><contrib contrib-type="author" id="au3"><name><surname>Yezli</surname><given-names>S.</given-names></name><xref rid="aff2" ref-type="aff">b</xref></contrib><contrib contrib-type="author" id="au4"><name><surname>Otter</surname><given-names>J.A.</given-names></name><xref rid="aff2" ref-type="aff">b</xref><xref rid="aff3" ref-type="aff">c</xref></contrib></contrib-group><aff id="aff1"><label>a</label>Department of Veterinary Population Medicine, University of Minnesota, Saint Paul, MN, USA</aff><aff id="aff2"><label>b</label>Bioquell UK Ltd, Andover, UK</aff><aff id="aff3"><label>c</label>Centre for Clinical Infection and Diagnostics Research (CIDR), Department of Infectious Diseases, King's College London School of Medicine and Guy’s and St Thomas’ NHS Foundation Trust, UK</aff><author-notes><corresp id="cor1"><label>∗</label>Corresponding author. Address: Department of Veterinary Population Medicine, University of Minnesota, 1333 Gortner Avenue, Saint Paul, MN 55108, USA. Tel.: +1 612 625 2714; fax: +1 612 624 8707. <email>goyal001@umn.edu</email></corresp></author-notes><pub-date pub-type="pmc-release"><day>27</day><month>2</month><year>2014</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><month>4</month><year>2014</year></pub-date><pub-date pub-type="epub"><day>27</day><month>2</month><year>2014</year></pub-date><volume>86</volume><issue>4</issue><fpage>255</fpage><lpage>259</lpage><history><date date-type="received"><day>1</day><month>2</month><year>2013</year></date><date date-type="accepted"><day>11</day><month>2</month><year>2014</year></date></history><permissions><copyright-statement>Copyright © 2014 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.</copyright-statement><copyright-year>2014</copyright-year><copyright-holder>The Healthcare Infection Society</copyright-holder><license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p></license></permissions><abstract id="abs0010"><title>Summary</title><sec><title>Background</title><p>Surface contamination has been implicated in the transmission of certain viruses, and surface disinfection can be an effective measure to interrupt the spread of these agents.</p></sec><sec><title>Aim</title><p>To evaluate the in-vitro efficacy of hydrogen peroxide vapour (HPV), a vapour-phase disinfection method, for the inactivation of a number of structurally distinct viruses of importance in the healthcare, veterinary and public sectors. The viruses studied were: feline calicivirus (FCV, a norovirus surrogate); human adenovirus type 1; transmissible gastroenteritis coronavirus of pigs (TGEV, a severe acute respiratory syndrome coronavirus [SARS-CoV] surrogate); avian influenza virus (AIV); and swine influenza virus (SwIV).</p></sec><sec><title>Methods</title><p>The viruses were dried on stainless steel discs in 20- or 40-μL aliquots and exposed to HPV produced by a Clarus L generator (Bioquell, Horsham, PA, USA) in a 0.2-m<sup>3</sup> environmental chamber. Three vaporized volumes of hydrogen peroxide were tested in triplicate for each virus: 25, 27 and 33 mL.</p></sec><sec><title>Findings</title><p>No viable viruses were identified after HPV exposure at any of the vaporized volumes tested. HPV was virucidal (>4-log reduction) against FCV, adenovirus, TGEV and AIV at the lowest vaporized volume tested (25 mL). For SwIV, due to low virus titre on the control discs, >3.8-log reduction was shown for the 25-mL vaporized volume and >4-log reduction was shown for the 27-mL and 33-mL vaporized volumes.</p></sec><sec><title>Conclusion</title><p>HPV was virucidal for structurally distinct viruses dried on surfaces, suggesting that HPV can be considered for the disinfection of virus-contaminated surfaces.</p></sec></abstract><kwd-group id="kwrds0010"><title>Keywords</title><kwd>Hydrogen peroxide vapour</kwd><kwd>HPV</kwd><kwd>Feline calicivirus</kwd><kwd>Norovirus</kwd><kwd>Influenza virus</kwd><kwd>Adenovirus</kwd><kwd>Transmissible gastroenteritis virus</kwd><kwd>SARS</kwd><kwd>Disinfection</kwd><kwd>Decontamination</kwd></kwd-group></article-meta></front></pmc><affiliations><list><country><li>Royaume-Uni</li><li>États-Unis</li></country><region><li>Minnesota</li></region></list><tree><country name="États-Unis"><region name="Minnesota"><name sortKey="Goyal, S M" sort="Goyal, S M" uniqKey="Goyal S" first="S. M." last="Goyal">S. M. Goyal</name></region><name sortKey="Chander, Y" sort="Chander, Y" uniqKey="Chander Y" first="Y." last="Chander">Y. Chander</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Yezli, S" sort="Yezli, S" uniqKey="Yezli S" first="S." last="Yezli">S. Yezli</name></noRegion><name sortKey="Otter, J A" sort="Otter, J A" uniqKey="Otter J" first="J. A." last="Otter">J. A. Otter</name><name sortKey="Otter, J A" sort="Otter, J A" uniqKey="Otter J" first="J. A." last="Otter">J. A. Otter</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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