Middle East respiratory syndrome: An emerging coronavirus infection tracked by the crowd
Identifieur interne : 000784 ( Pmc/Checkpoint ); précédent : 000783; suivant : 000785Middle East respiratory syndrome: An emerging coronavirus infection tracked by the crowd
Auteurs : Ian M. Mackay ; Katherine E. ArdenSource :
- Virus Research [ 0168-1702 ] ; 2015.
Abstract
Middle East respiratory syndrome coronavirus (MERS-CoV) is a severe, mild or subclinical infection. MERS is most severe among older men with comorbidities. MERS-CoV appears to be enzootic in camels throughout the Arabian peninsula and parts of Africa. MERS-CoV transmission occurs between humans and rare zoonotes. MERS cases often associated with hospitals and lack or absence of infection prevention and control.
Url:
DOI: 10.1016/j.virusres.2015.01.021
PubMed: 25656066
PubMed Central: 7114422
Affiliations:
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PMC:7114422Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Middle East respiratory syndrome: An emerging coronavirus infection tracked by the crowd</title><author><name sortKey="Mackay, Ian M" sort="Mackay, Ian M" uniqKey="Mackay I" first="Ian M." last="Mackay">Ian M. Mackay</name></author><author><name sortKey="Arden, Katherine E" sort="Arden, Katherine E" uniqKey="Arden K" first="Katherine E." last="Arden">Katherine E. Arden</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25656066</idno><idno type="pmc">7114422</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7114422</idno><idno type="RBID">PMC:7114422</idno><idno type="doi">10.1016/j.virusres.2015.01.021</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">001606</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001606</idno><idno type="wicri:Area/Pmc/Curation">001606</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001606</idno><idno type="wicri:Area/Pmc/Checkpoint">000784</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000784</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Middle East respiratory syndrome: An emerging coronavirus infection tracked by the crowd</title><author><name sortKey="Mackay, Ian M" sort="Mackay, Ian M" uniqKey="Mackay I" first="Ian M." last="Mackay">Ian M. Mackay</name></author><author><name sortKey="Arden, Katherine E" sort="Arden, Katherine E" uniqKey="Arden K" first="Katherine E." last="Arden">Katherine E. Arden</name></author></analytic><series><title level="j">Virus Research</title><idno type="ISSN">0168-1702</idno><idno type="eISSN">1872-7492</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Highlights</title><p><list list-type="simple" id="lis0005"><list-item id="lsti0260"><label>•</label><p id="par0645">Middle East respiratory syndrome coronavirus (MERS-CoV) is a severe, mild or subclinical infection.</p></list-item><list-item id="lsti0010"><label>•</label><p id="par0010">MERS is most severe among older men with comorbidities.</p></list-item><list-item id="lsti0015"><label>•</label><p id="par0015">MERS-CoV appears to be enzootic in camels throughout the Arabian peninsula and parts of Africa.</p></list-item><list-item id="lsti0020"><label>•</label><p id="par0020">MERS-CoV transmission occurs between humans and rare zoonotes.</p></list-item><list-item id="lsti0025"><label>•</label><p id="par0025">MERS cases often associated with hospitals and lack or absence of infection prevention and control.</p></list-item></list></p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Abdel Moneim, A S" uniqKey="Abdel Moneim A">A.S. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Virus Res</journal-id><journal-id journal-id-type="iso-abbrev">Virus Res</journal-id><journal-title-group><journal-title>Virus Research</journal-title></journal-title-group><issn pub-type="ppub">0168-1702</issn><issn pub-type="epub">1872-7492</issn><publisher><publisher-name>Elsevier B.V.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">25656066</article-id><article-id pub-id-type="pmc">7114422</article-id><article-id pub-id-type="publisher-id">S0168-1702(15)00046-5</article-id><article-id pub-id-type="doi">10.1016/j.virusres.2015.01.021</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Middle East respiratory syndrome: An emerging coronavirus infection tracked by the crowd</article-title></title-group><contrib-group><contrib contrib-type="author" id="aut0005"><name><surname>Mackay</surname><given-names>Ian M.</given-names></name><email>ian.mackay@uq.edu.au</email><xref rid="cor0005" ref-type="corresp">⁎</xref></contrib><contrib contrib-type="author" id="aut0010"><name><surname>Arden</surname><given-names>Katherine E.</given-names></name></contrib></contrib-group><aff id="aff0005">Queensland Paediatric Infectious Diseases Laboratory, Queensland Children's Medical Research Institute, The University of Queensland, Brisbane, Australia</aff><author-notes><corresp id="cor0005"><label>⁎</label>Corresponding author at: Level 7, SASVRC, Building C18, Back Road off Bramston Terrace, Royal Brisbane and Women's Hospital, Herston Q4029, Australia. Tel.: +61 7 3636 1619. <email>ian.mackay@uq.edu.au</email></corresp></author-notes><pub-date pub-type="pmc-release"><day>2</day><month>2</month><year>2015</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><day>16</day><month>4</month><year>2015</year></pub-date><pub-date pub-type="epub"><day>2</day><month>2</month><year>2015</year></pub-date><volume>202</volume><fpage>60</fpage><lpage>88</lpage><permissions><copyright-statement>Copyright © 2015 Elsevier B.V. All rights reserved.</copyright-statement><copyright-year>2015</copyright-year><copyright-holder>Elsevier B.V.</copyright-holder><license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p></license></permissions><abstract abstract-type="author-highlights" id="abs0005"><title>Highlights</title><p><list list-type="simple" id="lis0005"><list-item id="lsti0260"><label>•</label><p id="par0645">Middle East respiratory syndrome coronavirus (MERS-CoV) is a severe, mild or subclinical infection.</p></list-item><list-item id="lsti0010"><label>•</label><p id="par0010">MERS is most severe among older men with comorbidities.</p></list-item><list-item id="lsti0015"><label>•</label><p id="par0015">MERS-CoV appears to be enzootic in camels throughout the Arabian peninsula and parts of Africa.</p></list-item><list-item id="lsti0020"><label>•</label><p id="par0020">MERS-CoV transmission occurs between humans and rare zoonotes.</p></list-item><list-item id="lsti0025"><label>•</label><p id="par0025">MERS cases often associated with hospitals and lack or absence of infection prevention and control.</p></list-item></list></p></abstract><abstract id="abs0010"><p>In 2012 in Jordan, infection by a novel coronavirus (CoV) caused the first known cases of Middle East respiratory syndrome (MERS). MERS-CoV sequences have since been found in a bat and the virus appears to be enzootic among dromedary camels across the Arabian Peninsula and in parts of Africa. The majority of human cases have occurred in the Kingdom of Saudi Arabia (KSA). In humans, the etiologic agent, MERS-CoV, has been detected in severe, mild and influenza-like illness and in those without any obvious signs or symptoms of disease. MERS is often a lower respiratory tract disease associated with fever, cough, breathing difficulties, pneumonia that can progress to acute respiratory distress syndrome, multiorgan failure and death among more than a third of those infected. Severe disease is usually found in older males and comorbidities are frequently present in cases of MERS. Compared to SARS, MERS progresses more rapidly to respiratory failure and acute kidney injury, is more often observed as severe disease in patients with underlying illnesses and is more often fatal. MERS-CoV has a broader tropism than SARS-CoV, rapidly triggers cellular damage, employs a different receptor and induces a delayed proinflammatory response in cells. Most human cases have been linked to lapses in infection prevention and control in healthcare settings, with a fifth of virus detections reported among healthcare workers. This review sets out what is currently known about MERS and the MERS-CoV, summarises the new phenomenon of crowd-sourced epidemiology and lists some of the many questions that remain unanswered, nearly three years after the first reported case.</p></abstract><kwd-group id="kwd0005"><title>Keywords</title><kwd>MERS-CoV</kwd><kwd>MERS</kwd><kwd>Camel</kwd><kwd>Zoonosis</kwd><kwd>Healthcare worker</kwd><kwd>Emerging infectious disease</kwd></kwd-group></article-meta></front></pmc><affiliations><list></list><tree><noCountry><name sortKey="Arden, Katherine E" sort="Arden, Katherine E" uniqKey="Arden K" first="Katherine E." last="Arden">Katherine E. Arden</name><name sortKey="Mackay, Ian M" sort="Mackay, Ian M" uniqKey="Mackay I" first="Ian M." last="Mackay">Ian M. Mackay</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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