Human Coronaviruses: General Features
Identifieur interne : 000453 ( Pmc/Checkpoint ); précédent : 000452; suivant : 000454Human Coronaviruses: General Features
Auteurs : Xin Li ; Hayes K. H. LukSource :
- Reference Module in Biomedical Sciences ; 2019.
Abstract
Human coronaviruses (HCoVs), including HCoV-229E, HCoV-OC43, HCoV-NL63, and HCoV-HKU1, are traditionally known to cause symptoms of common cold with only moderate clinical impact. Severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV), on the other hand, have strike humans in the past two decades as highly fatal human pathogens leading to considerable mortality and economic loss. This article summaries the updates on the structure, genome organization, replication and clinical features of human coronaviruses. Recent studies also shed light upon the zoonotic origin of emerging human pathogens including SARS-CoV and MERS-CoV, providing insight for future surveillance and intervention.
Url:
DOI: 10.1016/B978-0-12-801238-3.95704-0
PubMed: NONE
PubMed Central: 7157439
Affiliations:
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<front><journal-meta><journal-id journal-id-type="nlm-ta">Reference Module in Biomedical Sciences</journal-id><journal-title-group><journal-title>Reference Module in Biomedical Sciences</journal-title></journal-title-group></journal-meta><article-meta><article-id pub-id-type="pmc">7157439</article-id><article-id pub-id-type="publisher-id">B978-0-12-801238-3.95704-0</article-id><article-id pub-id-type="doi">10.1016/B978-0-12-801238-3.95704-0</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Human Coronaviruses: General Features</article-title></title-group><contrib-group><contrib contrib-type="author" id="au0010"><name><surname>Li</surname><given-names>Xin</given-names></name></contrib><contrib contrib-type="author" id="au0015"><name><surname>Luk</surname><given-names>Hayes K.H.</given-names></name></contrib></contrib-group><aff id="af0010">The University of Hong Kong, Hong Kong, China</aff><contrib-group><contrib contrib-type="author" id="au0020"><name><surname>Lau</surname><given-names>Susanna K.P.</given-names></name><email>skplau@hku.hk</email></contrib><contrib contrib-type="author" id="au0025"><name><surname>Woo</surname><given-names>Patrick C.Y.</given-names></name><email>pcywoo@hku.hk</email></contrib></contrib-group><aff id="af0015">The University of Hong Kong, Hong Kong, China</aff><aff id="af0020">Zhejiang University, Hangzhou, China</aff><pub-date pub-type="pmc-release"><day>11</day><month>3</month><year>2019</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><year>2019</year></pub-date><pub-date pub-type="epub"><day>11</day><month>3</month><year>2019</year></pub-date><elocation-id>B978-0-12-801238-3.95704-0</elocation-id><permissions><copyright-statement>Copyright © 2019 Elsevier Inc. All rights reserved.</copyright-statement><copyright-year>2019</copyright-year><copyright-holder>Elsevier Inc.</copyright-holder><license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p></license></permissions><abstract id="ab0010"><p>Human coronaviruses (HCoVs), including HCoV-229E, HCoV-OC43, HCoV-NL63, and HCoV-HKU1, are traditionally known to cause symptoms of common cold with only moderate clinical impact. Severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV), on the other hand, have strike humans in the past two decades as highly fatal human pathogens leading to considerable mortality and economic loss. This article summaries the updates on the structure, genome organization, replication and clinical features of human coronaviruses. Recent studies also shed light upon the zoonotic origin of emerging human pathogens including SARS-CoV and MERS-CoV, providing insight for future surveillance and intervention.</p></abstract><kwd-group id="ks0010"><title>Keywords</title><kwd>Epidemiology</kwd><kwd>Genome</kwd><kwd>Human coronavirus</kwd><kwd>MERS</kwd><kwd>Replication</kwd><kwd>SARS</kwd><kwd>Structure</kwd></kwd-group></article-meta></front></pmc><affiliations><list></list><tree><noCountry><name sortKey="Li, Xin" sort="Li, Xin" uniqKey="Li X" first="Xin" last="Li">Xin Li</name><name sortKey="Luk, Hayes K H" sort="Luk, Hayes K H" uniqKey="Luk H" first="Hayes K. H." last="Luk">Hayes K. H. Luk</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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