First known person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA
Identifieur interne : 000248 ( Pmc/Checkpoint ); précédent : 000247; suivant : 000249First known person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA
Auteurs : Isaac Ghinai [États-Unis] ; Tristan D. Mcpherson [États-Unis] ; Jennifer C. Hunter [États-Unis] ; Hannah L. Kirking [États-Unis] ; Demian Christiansen [États-Unis] ; Kiran Joshi [États-Unis] ; Rachel Rubin [États-Unis] ; Shirley Morales-Estrada [États-Unis] ; Stephanie R. Black [États-Unis] ; Massimo Pacilli [États-Unis] ; Marielle J. Fricchione [États-Unis] ; Rashmi K. Chugh [États-Unis] ; Kelly A. Walblay [États-Unis] ; N Seema Ahmed [États-Unis] ; William C. Stoecker [États-Unis] ; Nausheen F. Hasan [États-Unis] ; Deborah P. Burdsall [États-Unis] ; Heather E. Reese [États-Unis] ; Megan Wallace [États-Unis] ; Chen Wang [États-Unis] ; Darcie Moeller [États-Unis] ; Jacqueline Korpics [États-Unis] ; Shannon A. Novosad [États-Unis] ; Isaac Benowitz [États-Unis] ; Max W. Jacobs [États-Unis] ; Vishal S. Dasari [États-Unis] ; Megan T. Patel [États-Unis] ; Judy Kauerauf [États-Unis] ; E Matt Charles [États-Unis] ; Ngozi O. Ezike [États-Unis] ; Victoria Chu [États-Unis] ; Claire M. Midgley [États-Unis] ; Melissa A. Rolfes [États-Unis] ; Susan I. Gerber [États-Unis] ; Xiaoyan Lu [États-Unis] ; Stephen Lindstrom [États-Unis] ; Jennifer R. Verani [États-Unis] ; Jennifer E. Layden [États-Unis]Source :
- Lancet (London, England) [ 0140-6736 ] ; 2020.
Abstract
Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first detected in China in December, 2019. In January, 2020, state, local, and federal public health agencies investigated the first case of COVID-19 in Illinois, USA.
Patients with confirmed COVID-19 were defined as those with a positive SARS-CoV-2 test. Contacts were people with exposure to a patient with COVID-19 on or after the patient's symptom onset date. Contacts underwent active symptom monitoring for 14 days following their last exposure. Contacts who developed fever, cough, or shortness of breath became persons under investigation and were tested for SARS-CoV-2. A convenience sample of 32 asymptomatic health-care personnel contacts were also tested.
Patient 1—a woman in her 60s—returned from China in mid-January, 2020. One week later, she was hospitalised with pneumonia and tested positive for SARS-CoV-2. Her husband (Patient 2) did not travel but had frequent close contact with his wife. He was admitted 8 days later and tested positive for SARS-CoV-2. Overall, 372 contacts of both cases were identified; 347 underwent active symptom monitoring, including 152 community contacts and 195 health-care personnel. Of monitored contacts, 43 became persons under investigation, in addition to Patient 2. These 43 persons under investigation and all 32 asymptomatic health-care personnel tested negative for SARS-CoV-2.
Person-to-person transmission of SARS-CoV-2 occurred between two people with prolonged, unprotected exposure while Patient 1 was symptomatic. Despite active symptom monitoring and testing of symptomatic and some asymptomatic contacts, no further transmission was detected.
None.
Url:
DOI: 10.1016/S0140-6736(20)30607-3
PubMed: 32178768
PubMed Central: 7158585
Affiliations:
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PMC:7158585Le document en format XML
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</affiliation>
</author>
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<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gerber, Susan I" sort="Gerber, Susan I" uniqKey="Gerber S" first="Susan I" last="Gerber">Susan I. Gerber</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lu, Xiaoyan" sort="Lu, Xiaoyan" uniqKey="Lu X" first="Xiaoyan" last="Lu">Xiaoyan Lu</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lindstrom, Stephen" sort="Lindstrom, Stephen" uniqKey="Lindstrom S" first="Stephen" last="Lindstrom">Stephen Lindstrom</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Verani, Jennifer R" sort="Verani, Jennifer R" uniqKey="Verani J" first="Jennifer R" last="Verani">Jennifer R. Verani</name>
<affiliation wicri:level="2"><nlm:aff id="aff4">Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Layden, Jennifer E" sort="Layden, Jennifer E" uniqKey="Layden J" first="Jennifer E" last="Layden">Jennifer E. Layden</name>
<affiliation wicri:level="2"><nlm:aff id="aff8">Chicago Department of Public Health, Chicago, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Chicago Department of Public Health, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">First known person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA</title>
<author><name sortKey="Ghinai, Isaac" sort="Ghinai, Isaac" uniqKey="Ghinai I" first="Isaac" last="Ghinai">Isaac Ghinai</name>
<affiliation wicri:level="2"><nlm:aff id="aff1">Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="aff7">Illinois Department of Public Health, Springfield, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Illinois Department of Public Health, Springfield, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mcpherson, Tristan D" sort="Mcpherson, Tristan D" uniqKey="Mcpherson T" first="Tristan D" last="Mcpherson">Tristan D. Mcpherson</name>
<affiliation wicri:level="2"><nlm:aff id="aff1">Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="aff8">Chicago Department of Public Health, Chicago, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Chicago Department of Public Health, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hunter, Jennifer C" sort="Hunter, Jennifer C" uniqKey="Hunter J" first="Jennifer C" last="Hunter">Jennifer C. Hunter</name>
<affiliation wicri:level="2"><nlm:aff id="aff2">Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kirking, Hannah L" sort="Kirking, Hannah L" uniqKey="Kirking H" first="Hannah L" last="Kirking">Hannah L. Kirking</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Christiansen, Demian" sort="Christiansen, Demian" uniqKey="Christiansen D" first="Demian" last="Christiansen">Demian Christiansen</name>
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<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Cook County Department of Public Health, Oak Forest, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Joshi, Kiran" sort="Joshi, Kiran" uniqKey="Joshi K" first="Kiran" last="Joshi">Kiran Joshi</name>
<affiliation wicri:level="2"><nlm:aff id="aff9">Cook County Department of Public Health, Oak Forest, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Cook County Department of Public Health, Oak Forest, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rubin, Rachel" sort="Rubin, Rachel" uniqKey="Rubin R" first="Rachel" last="Rubin">Rachel Rubin</name>
<affiliation wicri:level="2"><nlm:aff id="aff9">Cook County Department of Public Health, Oak Forest, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Cook County Department of Public Health, Oak Forest, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Morales Estrada, Shirley" sort="Morales Estrada, Shirley" uniqKey="Morales Estrada S" first="Shirley" last="Morales-Estrada">Shirley Morales-Estrada</name>
<affiliation wicri:level="2"><nlm:aff id="aff9">Cook County Department of Public Health, Oak Forest, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Cook County Department of Public Health, Oak Forest, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Black, Stephanie R" sort="Black, Stephanie R" uniqKey="Black S" first="Stephanie R" last="Black">Stephanie R. Black</name>
<affiliation wicri:level="2"><nlm:aff id="aff8">Chicago Department of Public Health, Chicago, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Chicago Department of Public Health, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pacilli, Massimo" sort="Pacilli, Massimo" uniqKey="Pacilli M" first="Massimo" last="Pacilli">Massimo Pacilli</name>
<affiliation wicri:level="2"><nlm:aff id="aff8">Chicago Department of Public Health, Chicago, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Chicago Department of Public Health, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Fricchione, Marielle J" sort="Fricchione, Marielle J" uniqKey="Fricchione M" first="Marielle J" last="Fricchione">Marielle J. Fricchione</name>
<affiliation wicri:level="2"><nlm:aff id="aff8">Chicago Department of Public Health, Chicago, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Chicago Department of Public Health, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Chugh, Rashmi K" sort="Chugh, Rashmi K" uniqKey="Chugh R" first="Rashmi K" last="Chugh">Rashmi K. Chugh</name>
<affiliation wicri:level="2"><nlm:aff id="aff10">DuPage County Health Department, Wheaton, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>DuPage County Health Department, Wheaton, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Walblay, Kelly A" sort="Walblay, Kelly A" uniqKey="Walblay K" first="Kelly A" last="Walblay">Kelly A. Walblay</name>
<affiliation wicri:level="2"><nlm:aff id="aff8">Chicago Department of Public Health, Chicago, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Chicago Department of Public Health, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ahmed, N Seema" sort="Ahmed, N Seema" uniqKey="Ahmed N" first="N Seema" last="Ahmed">N Seema Ahmed</name>
<affiliation wicri:level="2"><nlm:aff id="aff11">Metro Infectious Disease Consultants, Burr Ridge, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Metro Infectious Disease Consultants, Burr Ridge, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Stoecker, William C" sort="Stoecker, William C" uniqKey="Stoecker W" first="William C" last="Stoecker">William C. Stoecker</name>
<affiliation wicri:level="2"><nlm:aff id="aff11">Metro Infectious Disease Consultants, Burr Ridge, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Metro Infectious Disease Consultants, Burr Ridge, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hasan, Nausheen F" sort="Hasan, Nausheen F" uniqKey="Hasan N" first="Nausheen F" last="Hasan">Nausheen F. Hasan</name>
<affiliation wicri:level="2"><nlm:aff id="aff12">Premier Primary Care Physicians, Carol Stream, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Premier Primary Care Physicians, Carol Stream, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Burdsall, Deborah P" sort="Burdsall, Deborah P" uniqKey="Burdsall D" first="Deborah P" last="Burdsall">Deborah P. Burdsall</name>
<affiliation wicri:level="2"><nlm:aff id="aff7">Illinois Department of Public Health, Springfield, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Illinois Department of Public Health, Springfield, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Reese, Heather E" sort="Reese, Heather E" uniqKey="Reese H" first="Heather E" last="Reese">Heather E. Reese</name>
<affiliation wicri:level="2"><nlm:aff id="aff1">Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="aff4">Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wallace, Megan" sort="Wallace, Megan" uniqKey="Wallace M" first="Megan" last="Wallace">Megan Wallace</name>
<affiliation wicri:level="2"><nlm:aff id="aff1">Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="aff3">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Wang, Chen" sort="Wang, Chen" uniqKey="Wang C" first="Chen" last="Wang">Chen Wang</name>
<affiliation wicri:level="2"><nlm:aff id="aff13">Cook County Health, Chicago, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Cook County Health, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="aff14">Feinberg School of Medicine, Northwestern University, Chicago, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Feinberg School of Medicine, Northwestern University, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Moeller, Darcie" sort="Moeller, Darcie" uniqKey="Moeller D" first="Darcie" last="Moeller">Darcie Moeller</name>
<affiliation wicri:level="2"><nlm:aff id="aff13">Cook County Health, Chicago, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Cook County Health, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="aff14">Feinberg School of Medicine, Northwestern University, Chicago, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Feinberg School of Medicine, Northwestern University, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Korpics, Jacqueline" sort="Korpics, Jacqueline" uniqKey="Korpics J" first="Jacqueline" last="Korpics">Jacqueline Korpics</name>
<affiliation wicri:level="2"><nlm:aff id="aff13">Cook County Health, Chicago, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Cook County Health, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="aff14">Feinberg School of Medicine, Northwestern University, Chicago, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Feinberg School of Medicine, Northwestern University, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Novosad, Shannon A" sort="Novosad, Shannon A" uniqKey="Novosad S" first="Shannon A" last="Novosad">Shannon A. Novosad</name>
<affiliation wicri:level="2"><nlm:aff id="aff2">Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Benowitz, Isaac" sort="Benowitz, Isaac" uniqKey="Benowitz I" first="Isaac" last="Benowitz">Isaac Benowitz</name>
<affiliation wicri:level="2"><nlm:aff id="aff2">Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Jacobs, Max W" sort="Jacobs, Max W" uniqKey="Jacobs M" first="Max W" last="Jacobs">Max W. Jacobs</name>
<affiliation wicri:level="2"><nlm:aff id="aff5">Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="aff15">Lake Erie College of Osteopathic Medicine, Erie, PA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Lake Erie College of Osteopathic Medicine, Erie, PA</wicri:regionArea>
<placeName><region type="state">Pennsylvanie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Dasari, Vishal S" sort="Dasari, Vishal S" uniqKey="Dasari V" first="Vishal S" last="Dasari">Vishal S. Dasari</name>
<affiliation wicri:level="2"><nlm:aff id="aff6">One Health Office, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>One Health Office, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="aff16">Boonshoft School of Medicine, Wright State University, Dayton, OH, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Boonshoft School of Medicine, Wright State University, Dayton, OH</wicri:regionArea>
<placeName><region type="state">Ohio</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Patel, Megan T" sort="Patel, Megan T" uniqKey="Patel M" first="Megan T" last="Patel">Megan T. Patel</name>
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<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Illinois Department of Public Health, Springfield, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kauerauf, Judy" sort="Kauerauf, Judy" uniqKey="Kauerauf J" first="Judy" last="Kauerauf">Judy Kauerauf</name>
<affiliation wicri:level="2"><nlm:aff id="aff7">Illinois Department of Public Health, Springfield, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Illinois Department of Public Health, Springfield, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Charles, E Matt" sort="Charles, E Matt" uniqKey="Charles E" first="E Matt" last="Charles">E Matt Charles</name>
<affiliation wicri:level="2"><nlm:aff id="aff7">Illinois Department of Public Health, Springfield, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Illinois Department of Public Health, Springfield, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ezike, Ngozi O" sort="Ezike, Ngozi O" uniqKey="Ezike N" first="Ngozi O" last="Ezike">Ngozi O. Ezike</name>
<affiliation wicri:level="2"><nlm:aff id="aff7">Illinois Department of Public Health, Springfield, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Illinois Department of Public Health, Springfield, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Chu, Victoria" sort="Chu, Victoria" uniqKey="Chu V" first="Victoria" last="Chu">Victoria Chu</name>
<affiliation wicri:level="2"><nlm:aff id="aff1">Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="aff3">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Midgley, Claire M" sort="Midgley, Claire M" uniqKey="Midgley C" first="Claire M" last="Midgley">Claire M. Midgley</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rolfes, Melissa A" sort="Rolfes, Melissa A" uniqKey="Rolfes M" first="Melissa A" last="Rolfes">Melissa A. Rolfes</name>
<affiliation wicri:level="2"><nlm:aff id="aff5">Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gerber, Susan I" sort="Gerber, Susan I" uniqKey="Gerber S" first="Susan I" last="Gerber">Susan I. Gerber</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lu, Xiaoyan" sort="Lu, Xiaoyan" uniqKey="Lu X" first="Xiaoyan" last="Lu">Xiaoyan Lu</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lindstrom, Stephen" sort="Lindstrom, Stephen" uniqKey="Lindstrom S" first="Stephen" last="Lindstrom">Stephen Lindstrom</name>
<affiliation wicri:level="2"><nlm:aff id="aff3">Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Verani, Jennifer R" sort="Verani, Jennifer R" uniqKey="Verani J" first="Jennifer R" last="Verani">Jennifer R. Verani</name>
<affiliation wicri:level="2"><nlm:aff id="aff4">Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA</wicri:regionArea>
<placeName><region type="state">Géorgie (États-Unis)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Layden, Jennifer E" sort="Layden, Jennifer E" uniqKey="Layden J" first="Jennifer E" last="Layden">Jennifer E. Layden</name>
<affiliation wicri:level="2"><nlm:aff id="aff8">Chicago Department of Public Health, Chicago, IL, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Chicago Department of Public Health, Chicago, IL</wicri:regionArea>
<placeName><region type="state">Illinois</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Lancet (London, England)</title>
<idno type="ISSN">0140-6736</idno>
<idno type="eISSN">1474-547X</idno>
<imprint><date when="2020">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><title>Summary</title>
<sec><title>Background</title>
<p>Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first detected in China in December, 2019. In January, 2020, state, local, and federal public health agencies investigated the first case of COVID-19 in Illinois, USA.</p>
</sec>
<sec><title>Methods</title>
<p>Patients with confirmed COVID-19 were defined as those with a positive SARS-CoV-2 test. Contacts were people with exposure to a patient with COVID-19 on or after the patient's symptom onset date. Contacts underwent active symptom monitoring for 14 days following their last exposure. Contacts who developed fever, cough, or shortness of breath became persons under investigation and were tested for SARS-CoV-2. A convenience sample of 32 asymptomatic health-care personnel contacts were also tested.</p>
</sec>
<sec><title>Findings</title>
<p>Patient 1—a woman in her 60s—returned from China in mid-January, 2020. One week later, she was hospitalised with pneumonia and tested positive for SARS-CoV-2. Her husband (Patient 2) did not travel but had frequent close contact with his wife. He was admitted 8 days later and tested positive for SARS-CoV-2. Overall, 372 contacts of both cases were identified; 347 underwent active symptom monitoring, including 152 community contacts and 195 health-care personnel. Of monitored contacts, 43 became persons under investigation, in addition to Patient 2. These 43 persons under investigation and all 32 asymptomatic health-care personnel tested negative for SARS-CoV-2.</p>
</sec>
<sec><title>Interpretation</title>
<p>Person-to-person transmission of SARS-CoV-2 occurred between two people with prolonged, unprotected exposure while Patient 1 was symptomatic. Despite active symptom monitoring and testing of symptomatic and some asymptomatic contacts, no further transmission was detected.</p>
</sec>
<sec><title>Funding</title>
<p>None.</p>
</sec>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Lu, R" uniqKey="Lu R">R Lu</name>
</author>
<author><name sortKey="Zhao, X" uniqKey="Zhao X">X Zhao</name>
</author>
<author><name sortKey="Li, J" uniqKey="Li J">J Li</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chan, Jf W" uniqKey="Chan J">JF-W Chan</name>
</author>
<author><name sortKey="Yuan, S" uniqKey="Yuan S">S Yuan</name>
</author>
<author><name sortKey="Kok, K H" uniqKey="Kok K">K-H Kok</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Phan, L" uniqKey="Phan L">L Phan</name>
</author>
<author><name sortKey="Nguyen, T" uniqKey="Nguyen T">T Nguyen</name>
</author>
<author><name sortKey="Luong, Q" uniqKey="Luong Q">Q Luong</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Li, Q" uniqKey="Li Q">Q Li</name>
</author>
<author><name sortKey="Guan, X" uniqKey="Guan X">X Guan</name>
</author>
<author><name sortKey="Wu, P" uniqKey="Wu P">P Wu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chen, N" uniqKey="Chen N">N Chen</name>
</author>
<author><name sortKey="Zhou, M" uniqKey="Zhou M">M Zhou</name>
</author>
<author><name sortKey="Dong, X" uniqKey="Dong X">X Dong</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Park, Sw" uniqKey="Park S">SW Park</name>
</author>
<author><name sortKey="Bolker, Bm" uniqKey="Bolker B">BM Bolker</name>
</author>
<author><name sortKey="Champredon, D" uniqKey="Champredon D">D Champredon</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Chowell, G" uniqKey="Chowell G">G Chowell</name>
</author>
<author><name sortKey="Abdirizak, F" uniqKey="Abdirizak F">F Abdirizak</name>
</author>
<author><name sortKey="Lee, S" uniqKey="Lee S">S Lee</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Cowling, Bj" uniqKey="Cowling B">BJ Cowling</name>
</author>
<author><name sortKey="Park, M" uniqKey="Park M">M Park</name>
</author>
<author><name sortKey="Fang, Vj" uniqKey="Fang V">VJ Fang</name>
</author>
<author><name sortKey="Wu, P" uniqKey="Wu P">P Wu</name>
</author>
<author><name sortKey="Leung, Gm" uniqKey="Leung G">GM Leung</name>
</author>
<author><name sortKey="Wu, Jt" uniqKey="Wu J">JT Wu</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Shen, Z" uniqKey="Shen Z">Z Shen</name>
</author>
<author><name sortKey="Ning, F" uniqKey="Ning F">F Ning</name>
</author>
<author><name sortKey="Zhou, W" uniqKey="Zhou W">W Zhou</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Holshue, M" uniqKey="Holshue M">M Holshue</name>
</author>
<author><name sortKey="Debolt, C" uniqKey="Debolt C">C DeBolt</name>
</author>
<author><name sortKey="Lindquist, S" uniqKey="Lindquist S">S Lindquist</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Lancet</journal-id>
<journal-id journal-id-type="iso-abbrev">Lancet</journal-id>
<journal-title-group><journal-title>Lancet (London, England)</journal-title>
</journal-title-group>
<issn pub-type="ppub">0140-6736</issn>
<issn pub-type="epub">1474-547X</issn>
<publisher><publisher-name>Elsevier Ltd.</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">32178768</article-id>
<article-id pub-id-type="pmc">7158585</article-id>
<article-id pub-id-type="publisher-id">S0140-6736(20)30607-3</article-id>
<article-id pub-id-type="doi">10.1016/S0140-6736(20)30607-3</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>First known person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA</article-title>
</title-group>
<contrib-group><contrib contrib-type="author" id="au10"><name><surname>Ghinai</surname>
<given-names>Isaac</given-names>
</name>
<degrees>MBBS</degrees>
<xref rid="aff1" ref-type="aff">a</xref>
<xref rid="fn1" ref-type="fn">*</xref>
<xref rid="aff7" ref-type="aff">g</xref>
</contrib>
<contrib contrib-type="author" id="au20"><name><surname>McPherson</surname>
<given-names>Tristan D</given-names>
</name>
<degrees>MD</degrees>
<email>oko9@cdc.gov</email>
<xref rid="aff1" ref-type="aff">a</xref>
<xref rid="aff8" ref-type="aff">h</xref>
<xref rid="cor1" ref-type="corresp">*</xref>
<xref rid="fn1" ref-type="fn">*</xref>
</contrib>
<contrib contrib-type="author" id="au30"><name><surname>Hunter</surname>
<given-names>Jennifer C</given-names>
</name>
<degrees>DrPH</degrees>
<xref rid="aff2" ref-type="aff">b</xref>
</contrib>
<contrib contrib-type="author" id="au40"><name><surname>Kirking</surname>
<given-names>Hannah L</given-names>
</name>
<degrees>MD</degrees>
<xref rid="aff3" ref-type="aff">c</xref>
</contrib>
<contrib contrib-type="author" id="au50"><name><surname>Christiansen</surname>
<given-names>Demian</given-names>
</name>
<degrees>DrPH</degrees>
<xref rid="aff9" ref-type="aff">i</xref>
</contrib>
<contrib contrib-type="author" id="au60"><name><surname>Joshi</surname>
<given-names>Kiran</given-names>
</name>
<degrees>MD</degrees>
<xref rid="aff9" ref-type="aff">i</xref>
</contrib>
<contrib contrib-type="author" id="au70"><name><surname>Rubin</surname>
<given-names>Rachel</given-names>
</name>
<degrees>MD</degrees>
<xref rid="aff9" ref-type="aff">i</xref>
</contrib>
<contrib contrib-type="author" id="au80"><name><surname>Morales-Estrada</surname>
<given-names>Shirley</given-names>
</name>
<degrees>MPH</degrees>
<xref rid="aff9" ref-type="aff">i</xref>
</contrib>
<contrib contrib-type="author" id="au90"><name><surname>Black</surname>
<given-names>Stephanie R</given-names>
</name>
<degrees>MD</degrees>
<xref rid="aff8" ref-type="aff">h</xref>
</contrib>
<contrib contrib-type="author" id="au100"><name><surname>Pacilli</surname>
<given-names>Massimo</given-names>
</name>
<degrees>MPH</degrees>
<xref rid="aff8" ref-type="aff">h</xref>
</contrib>
<contrib contrib-type="author" id="au110"><name><surname>Fricchione</surname>
<given-names>Marielle J</given-names>
</name>
<degrees>MD</degrees>
<xref rid="aff8" ref-type="aff">h</xref>
</contrib>
<contrib contrib-type="author" id="au120"><name><surname>Chugh</surname>
<given-names>Rashmi K</given-names>
</name>
<degrees>MD</degrees>
<xref rid="aff10" ref-type="aff">j</xref>
</contrib>
<contrib contrib-type="author" id="au130"><name><surname>Walblay</surname>
<given-names>Kelly A</given-names>
</name>
<degrees>MPH</degrees>
<xref rid="aff8" ref-type="aff">h</xref>
</contrib>
<contrib contrib-type="author" id="au140"><name><surname>Ahmed</surname>
<given-names>N Seema</given-names>
</name>
<degrees>MD</degrees>
<xref rid="aff11" ref-type="aff">k</xref>
</contrib>
<contrib contrib-type="author" id="au150"><name><surname>Stoecker</surname>
<given-names>William C</given-names>
</name>
<degrees>MD</degrees>
<xref rid="aff11" ref-type="aff">k</xref>
</contrib>
<contrib contrib-type="author" id="au160"><name><surname>Hasan</surname>
<given-names>Nausheen F</given-names>
</name>
<degrees>MD</degrees>
<xref rid="aff12" ref-type="aff">l</xref>
</contrib>
<contrib contrib-type="author" id="au170"><name><surname>Burdsall</surname>
<given-names>Deborah P</given-names>
</name>
<degrees>PhD</degrees>
<xref rid="aff7" ref-type="aff">g</xref>
</contrib>
<contrib contrib-type="author" id="au180"><name><surname>Reese</surname>
<given-names>Heather E</given-names>
</name>
<degrees>PhD</degrees>
<xref rid="aff1" ref-type="aff">a</xref>
<xref rid="aff4" ref-type="aff">d</xref>
</contrib>
<contrib contrib-type="author" id="au190"><name><surname>Wallace</surname>
<given-names>Megan</given-names>
</name>
<degrees>DrPH</degrees>
<xref rid="aff1" ref-type="aff">a</xref>
<xref rid="aff3" ref-type="aff">c</xref>
</contrib>
<contrib contrib-type="author" id="au200"><name><surname>Wang</surname>
<given-names>Chen</given-names>
</name>
<degrees>MD</degrees>
<xref rid="aff13" ref-type="aff">m</xref>
<xref rid="aff14" ref-type="aff">n</xref>
</contrib>
<contrib contrib-type="author" id="au210"><name><surname>Moeller</surname>
<given-names>Darcie</given-names>
</name>
<degrees>MD</degrees>
<xref rid="aff13" ref-type="aff">m</xref>
<xref rid="aff14" ref-type="aff">n</xref>
</contrib>
<contrib contrib-type="author" id="au220"><name><surname>Korpics</surname>
<given-names>Jacqueline</given-names>
</name>
<degrees>MD</degrees>
<xref rid="aff13" ref-type="aff">m</xref>
<xref rid="aff14" ref-type="aff">n</xref>
</contrib>
<contrib contrib-type="author" id="au230"><name><surname>Novosad</surname>
<given-names>Shannon A</given-names>
</name>
<degrees>MD</degrees>
<xref rid="aff2" ref-type="aff">b</xref>
</contrib>
<contrib contrib-type="author" id="au240"><name><surname>Benowitz</surname>
<given-names>Isaac</given-names>
</name>
<degrees>MD</degrees>
<xref rid="aff2" ref-type="aff">b</xref>
</contrib>
<contrib contrib-type="author" id="au250"><name><surname>Jacobs</surname>
<given-names>Max W</given-names>
</name>
<degrees>BA</degrees>
<xref rid="aff5" ref-type="aff">e</xref>
<xref rid="aff15" ref-type="aff">o</xref>
</contrib>
<contrib contrib-type="author" id="au260"><name><surname>Dasari</surname>
<given-names>Vishal S</given-names>
</name>
<degrees>MPH</degrees>
<xref rid="aff6" ref-type="aff">f</xref>
<xref rid="aff16" ref-type="aff">p</xref>
</contrib>
<contrib contrib-type="author" id="au270"><name><surname>Patel</surname>
<given-names>Megan T</given-names>
</name>
<degrees>MPH</degrees>
<xref rid="aff7" ref-type="aff">g</xref>
</contrib>
<contrib contrib-type="author" id="au280"><name><surname>Kauerauf</surname>
<given-names>Judy</given-names>
</name>
<degrees>MPH</degrees>
<xref rid="aff7" ref-type="aff">g</xref>
</contrib>
<contrib contrib-type="author" id="au290"><name><surname>Charles</surname>
<given-names>E Matt</given-names>
</name>
<degrees>BA</degrees>
<xref rid="aff7" ref-type="aff">g</xref>
</contrib>
<contrib contrib-type="author" id="au300"><name><surname>Ezike</surname>
<given-names>Ngozi O</given-names>
</name>
<degrees>MD</degrees>
<xref rid="aff7" ref-type="aff">g</xref>
</contrib>
<contrib contrib-type="author" id="au310"><name><surname>Chu</surname>
<given-names>Victoria</given-names>
</name>
<degrees>MD</degrees>
<xref rid="aff1" ref-type="aff">a</xref>
<xref rid="aff3" ref-type="aff">c</xref>
</contrib>
<contrib contrib-type="author" id="au320"><name><surname>Midgley</surname>
<given-names>Claire M</given-names>
</name>
<degrees>PhD</degrees>
<xref rid="aff3" ref-type="aff">c</xref>
</contrib>
<contrib contrib-type="author" id="au330"><name><surname>Rolfes</surname>
<given-names>Melissa A</given-names>
</name>
<degrees>PhD</degrees>
<xref rid="aff5" ref-type="aff">e</xref>
</contrib>
<contrib contrib-type="author" id="au340"><name><surname>Gerber</surname>
<given-names>Susan I</given-names>
</name>
<degrees>MD</degrees>
<xref rid="aff3" ref-type="aff">c</xref>
</contrib>
<contrib contrib-type="author" id="au350"><name><surname>Lu</surname>
<given-names>Xiaoyan</given-names>
</name>
<degrees>MS</degrees>
<xref rid="aff3" ref-type="aff">c</xref>
</contrib>
<contrib contrib-type="author" id="au360"><name><surname>Lindstrom</surname>
<given-names>Stephen</given-names>
</name>
<degrees>PhD</degrees>
<xref rid="aff3" ref-type="aff">c</xref>
</contrib>
<contrib contrib-type="author" id="au370"><name><surname>Verani</surname>
<given-names>Jennifer R</given-names>
</name>
<degrees>MD</degrees>
<xref rid="aff4" ref-type="aff">d</xref>
</contrib>
<contrib contrib-type="author" id="au380"><name><surname>Layden</surname>
<given-names>Jennifer E</given-names>
</name>
<degrees>MD</degrees>
<email>jennifer.layden@cityofchicago.org</email>
<xref rid="aff8" ref-type="aff">h</xref>
<xref rid="cor2" ref-type="corresp">**</xref>
</contrib>
<on-behalf-of>for the Illinois COVID-19 Investigation Team<xref rid="fn2" ref-type="fn">†</xref>
</on-behalf-of>
</contrib-group>
<aff id="aff1"><label>a</label>
Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA, USA</aff>
<aff id="aff2"><label>b</label>
Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</aff>
<aff id="aff3"><label>c</label>
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</aff>
<aff id="aff4"><label>d</label>
Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</aff>
<aff id="aff5"><label>e</label>
Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</aff>
<aff id="aff6"><label>f</label>
One Health Office, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA</aff>
<aff id="aff7"><label>g</label>
Illinois Department of Public Health, Springfield, IL, USA</aff>
<aff id="aff8"><label>h</label>
Chicago Department of Public Health, Chicago, IL, USA</aff>
<aff id="aff9"><label>i</label>
Cook County Department of Public Health, Oak Forest, IL, USA</aff>
<aff id="aff10"><label>j</label>
DuPage County Health Department, Wheaton, IL, USA</aff>
<aff id="aff11"><label>k</label>
Metro Infectious Disease Consultants, Burr Ridge, IL, USA</aff>
<aff id="aff12"><label>l</label>
Premier Primary Care Physicians, Carol Stream, IL, USA</aff>
<aff id="aff13"><label>m</label>
Cook County Health, Chicago, IL, USA</aff>
<aff id="aff14"><label>n</label>
Feinberg School of Medicine, Northwestern University, Chicago, IL, USA</aff>
<aff id="aff15"><label>o</label>
Lake Erie College of Osteopathic Medicine, Erie, PA, USA</aff>
<aff id="aff16"><label>p</label>
Boonshoft School of Medicine, Wright State University, Dayton, OH, USA</aff>
<author-notes><corresp id="cor1"><label>*</label>
Correspondence to: Dr Tristan D McPherson, Chicago Department of Public Health, Chicago, IL 60612, USA <email>oko9@cdc.gov</email>
</corresp>
<corresp id="cor2"><label>**</label>
Dr Jennifer E Layden, Chicago Department of Public Health, Chicago, IL 60604, USA <email>jennifer.layden@cityofchicago.org</email>
</corresp>
<fn id="fn1"><label>*</label>
<p id="cenpara10">These authors contributed equally</p>
</fn>
<fn id="fn2"><label>†</label>
<p id="cenpara20">Memberrs of the Illinois COVID-19 Investigation Team are listed in the <xref rid="sec1" ref-type="sec">appendix (pp 1–2)</xref>
</p>
</fn>
</author-notes>
<pub-date pub-type="pmc-release"><day>13</day>
<month>3</month>
<year>2020</year>
</pub-date>
<pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub" iso-8601-date="2020-04-10"><season>4-10 April</season>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub"><day>13</day>
<month>3</month>
<year>2020</year>
</pub-date>
<volume>395</volume>
<issue>10230</issue>
<fpage>1137</fpage>
<lpage>1144</lpage>
<permissions><copyright-statement>© 2020 Elsevier Ltd. All rights reserved.</copyright-statement>
<copyright-year>2020</copyright-year>
<copyright-holder>Elsevier Ltd</copyright-holder>
<license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p>
</license>
</permissions>
<related-article related-article-type="article-reference" id="d32e381" ext-link-type="doi" xlink:href="10.1016/S0140-6736(20)30743-1"></related-article>
<abstract id="ceab10"><title>Summary</title>
<sec><title>Background</title>
<p>Coronavirus disease 2019 (COVID-19) is a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first detected in China in December, 2019. In January, 2020, state, local, and federal public health agencies investigated the first case of COVID-19 in Illinois, USA.</p>
</sec>
<sec><title>Methods</title>
<p>Patients with confirmed COVID-19 were defined as those with a positive SARS-CoV-2 test. Contacts were people with exposure to a patient with COVID-19 on or after the patient's symptom onset date. Contacts underwent active symptom monitoring for 14 days following their last exposure. Contacts who developed fever, cough, or shortness of breath became persons under investigation and were tested for SARS-CoV-2. A convenience sample of 32 asymptomatic health-care personnel contacts were also tested.</p>
</sec>
<sec><title>Findings</title>
<p>Patient 1—a woman in her 60s—returned from China in mid-January, 2020. One week later, she was hospitalised with pneumonia and tested positive for SARS-CoV-2. Her husband (Patient 2) did not travel but had frequent close contact with his wife. He was admitted 8 days later and tested positive for SARS-CoV-2. Overall, 372 contacts of both cases were identified; 347 underwent active symptom monitoring, including 152 community contacts and 195 health-care personnel. Of monitored contacts, 43 became persons under investigation, in addition to Patient 2. These 43 persons under investigation and all 32 asymptomatic health-care personnel tested negative for SARS-CoV-2.</p>
</sec>
<sec><title>Interpretation</title>
<p>Person-to-person transmission of SARS-CoV-2 occurred between two people with prolonged, unprotected exposure while Patient 1 was symptomatic. Despite active symptom monitoring and testing of symptomatic and some asymptomatic contacts, no further transmission was detected.</p>
</sec>
<sec><title>Funding</title>
<p>None.</p>
</sec>
</abstract>
</article-meta>
</front>
</pmc>
<affiliations><list><country><li>États-Unis</li>
</country>
<region><li>Géorgie (États-Unis)</li>
<li>Illinois</li>
<li>Ohio</li>
<li>Pennsylvanie</li>
</region>
</list>
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<name sortKey="Hunter, Jennifer C" sort="Hunter, Jennifer C" uniqKey="Hunter J" first="Jennifer C" last="Hunter">Jennifer C. Hunter</name>
<name sortKey="Jacobs, Max W" sort="Jacobs, Max W" uniqKey="Jacobs M" first="Max W" last="Jacobs">Max W. Jacobs</name>
<name sortKey="Jacobs, Max W" sort="Jacobs, Max W" uniqKey="Jacobs M" first="Max W" last="Jacobs">Max W. Jacobs</name>
<name sortKey="Joshi, Kiran" sort="Joshi, Kiran" uniqKey="Joshi K" first="Kiran" last="Joshi">Kiran Joshi</name>
<name sortKey="Kauerauf, Judy" sort="Kauerauf, Judy" uniqKey="Kauerauf J" first="Judy" last="Kauerauf">Judy Kauerauf</name>
<name sortKey="Kirking, Hannah L" sort="Kirking, Hannah L" uniqKey="Kirking H" first="Hannah L" last="Kirking">Hannah L. Kirking</name>
<name sortKey="Korpics, Jacqueline" sort="Korpics, Jacqueline" uniqKey="Korpics J" first="Jacqueline" last="Korpics">Jacqueline Korpics</name>
<name sortKey="Korpics, Jacqueline" sort="Korpics, Jacqueline" uniqKey="Korpics J" first="Jacqueline" last="Korpics">Jacqueline Korpics</name>
<name sortKey="Layden, Jennifer E" sort="Layden, Jennifer E" uniqKey="Layden J" first="Jennifer E" last="Layden">Jennifer E. Layden</name>
<name sortKey="Lindstrom, Stephen" sort="Lindstrom, Stephen" uniqKey="Lindstrom S" first="Stephen" last="Lindstrom">Stephen Lindstrom</name>
<name sortKey="Lu, Xiaoyan" sort="Lu, Xiaoyan" uniqKey="Lu X" first="Xiaoyan" last="Lu">Xiaoyan Lu</name>
<name sortKey="Mcpherson, Tristan D" sort="Mcpherson, Tristan D" uniqKey="Mcpherson T" first="Tristan D" last="Mcpherson">Tristan D. Mcpherson</name>
<name sortKey="Mcpherson, Tristan D" sort="Mcpherson, Tristan D" uniqKey="Mcpherson T" first="Tristan D" last="Mcpherson">Tristan D. Mcpherson</name>
<name sortKey="Midgley, Claire M" sort="Midgley, Claire M" uniqKey="Midgley C" first="Claire M" last="Midgley">Claire M. Midgley</name>
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<name sortKey="Moeller, Darcie" sort="Moeller, Darcie" uniqKey="Moeller D" first="Darcie" last="Moeller">Darcie Moeller</name>
<name sortKey="Morales Estrada, Shirley" sort="Morales Estrada, Shirley" uniqKey="Morales Estrada S" first="Shirley" last="Morales-Estrada">Shirley Morales-Estrada</name>
<name sortKey="Novosad, Shannon A" sort="Novosad, Shannon A" uniqKey="Novosad S" first="Shannon A" last="Novosad">Shannon A. Novosad</name>
<name sortKey="Pacilli, Massimo" sort="Pacilli, Massimo" uniqKey="Pacilli M" first="Massimo" last="Pacilli">Massimo Pacilli</name>
<name sortKey="Patel, Megan T" sort="Patel, Megan T" uniqKey="Patel M" first="Megan T" last="Patel">Megan T. Patel</name>
<name sortKey="Reese, Heather E" sort="Reese, Heather E" uniqKey="Reese H" first="Heather E" last="Reese">Heather E. Reese</name>
<name sortKey="Reese, Heather E" sort="Reese, Heather E" uniqKey="Reese H" first="Heather E" last="Reese">Heather E. Reese</name>
<name sortKey="Rolfes, Melissa A" sort="Rolfes, Melissa A" uniqKey="Rolfes M" first="Melissa A" last="Rolfes">Melissa A. Rolfes</name>
<name sortKey="Rubin, Rachel" sort="Rubin, Rachel" uniqKey="Rubin R" first="Rachel" last="Rubin">Rachel Rubin</name>
<name sortKey="Stoecker, William C" sort="Stoecker, William C" uniqKey="Stoecker W" first="William C" last="Stoecker">William C. Stoecker</name>
<name sortKey="Verani, Jennifer R" sort="Verani, Jennifer R" uniqKey="Verani J" first="Jennifer R" last="Verani">Jennifer R. Verani</name>
<name sortKey="Walblay, Kelly A" sort="Walblay, Kelly A" uniqKey="Walblay K" first="Kelly A" last="Walblay">Kelly A. Walblay</name>
<name sortKey="Wallace, Megan" sort="Wallace, Megan" uniqKey="Wallace M" first="Megan" last="Wallace">Megan Wallace</name>
<name sortKey="Wallace, Megan" sort="Wallace, Megan" uniqKey="Wallace M" first="Megan" last="Wallace">Megan Wallace</name>
<name sortKey="Wang, Chen" sort="Wang, Chen" uniqKey="Wang C" first="Chen" last="Wang">Chen Wang</name>
<name sortKey="Wang, Chen" sort="Wang, Chen" uniqKey="Wang C" first="Chen" last="Wang">Chen Wang</name>
</country>
</tree>
</affiliations>
</record>
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