The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak
Identifieur interne : 000032 ( Pmc/Checkpoint ); précédent : 000031; suivant : 000033The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak
Auteurs : Hussin A. Rothan [États-Unis] ; Siddappa N. Byrareddy [États-Unis]Source :
- Journal of Autoimmunity [ 0896-8411 ] ; 2020.
Abstract
Coronavirus disease (COVID-19) is caused by SARS-COV2 and represents the causative agent of a potentially fatal disease that is of great global public health concern. Based on the large number of infected people that were exposed to the wet animal market in Wuhan City, China, it is suggested that this is likely the zoonotic origin of COVID-19. Person-to-person transmission of COVID-19 infection led to the isolation of patients that were subsequently administered a variety of treatments. Extensive measures to reduce person-to-person transmission of COVID-19 have been implemented to control the current outbreak. Special attention and efforts to protect or reduce transmission should be applied in susceptible populations including children, health care providers, and elderly people. In this review, we highlights the symptoms, epidemiology, transmission, pathogenesis, phylogenetic analysis and future directions to control the spread of this fatal disease.
Url:
DOI: 10.1016/j.jaut.2020.102433
PubMed: 32113704
PubMed Central: 7127067
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak</title><author><name sortKey="Rothan, Hussin A" sort="Rothan, Hussin A" uniqKey="Rothan H" first="Hussin A." last="Rothan">Hussin A. Rothan</name><affiliation wicri:level="2"><nlm:aff id="aff1">Department of Biology, College of Arts and Sciences, Georgia State University, Atlanta, GA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biology, College of Arts and Sciences, Georgia State University, Atlanta, GA</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Byrareddy, Siddappa N" sort="Byrareddy, Siddappa N" uniqKey="Byrareddy S" first="Siddappa N." last="Byrareddy">Siddappa N. Byrareddy</name><affiliation wicri:level="2"><nlm:aff id="aff2">Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Centre, Omaha, NE, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Centre, Omaha, NE</wicri:regionArea><placeName><region type="state">Nebraska</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff3">Department of Genetics, Cell Biology and Anatomy, Omaha, NE, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, Cell Biology and Anatomy, Omaha, NE</wicri:regionArea><placeName><region type="state">Nebraska</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff4">Department of Biochemistry and Molecular Biology, University of Nebraska Medical Centre, Omaha, NE, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, University of Nebraska Medical Centre, Omaha, NE</wicri:regionArea><placeName><region type="state">Nebraska</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">32113704</idno><idno type="pmc">7127067</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127067</idno><idno type="RBID">PMC:7127067</idno><idno type="doi">10.1016/j.jaut.2020.102433</idno><date when="2020">2020</date><idno type="wicri:Area/Pmc/Corpus">001811</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001811</idno><idno type="wicri:Area/Pmc/Curation">001811</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001811</idno><idno type="wicri:Area/Pmc/Checkpoint">000032</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000032</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak</title><author><name sortKey="Rothan, Hussin A" sort="Rothan, Hussin A" uniqKey="Rothan H" first="Hussin A." last="Rothan">Hussin A. Rothan</name><affiliation wicri:level="2"><nlm:aff id="aff1">Department of Biology, College of Arts and Sciences, Georgia State University, Atlanta, GA, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biology, College of Arts and Sciences, Georgia State University, Atlanta, GA</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author><author><name sortKey="Byrareddy, Siddappa N" sort="Byrareddy, Siddappa N" uniqKey="Byrareddy S" first="Siddappa N." last="Byrareddy">Siddappa N. Byrareddy</name><affiliation wicri:level="2"><nlm:aff id="aff2">Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Centre, Omaha, NE, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Centre, Omaha, NE</wicri:regionArea><placeName><region type="state">Nebraska</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff3">Department of Genetics, Cell Biology and Anatomy, Omaha, NE, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Genetics, Cell Biology and Anatomy, Omaha, NE</wicri:regionArea><placeName><region type="state">Nebraska</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff4">Department of Biochemistry and Molecular Biology, University of Nebraska Medical Centre, Omaha, NE, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, University of Nebraska Medical Centre, Omaha, NE</wicri:regionArea><placeName><region type="state">Nebraska</region></placeName></affiliation></author></analytic><series><title level="j">Journal of Autoimmunity</title><idno type="ISSN">0896-8411</idno><idno type="eISSN">1095-9157</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Coronavirus disease (COVID-19) is caused by SARS-COV2 and represents the causative agent of a potentially fatal disease that is of great global public health concern. Based on the large number of infected people that were exposed to the wet animal market in Wuhan City, China, it is suggested that this is likely the zoonotic origin of COVID-19. Person-to-person transmission of COVID-19 infection led to the isolation of patients that were subsequently administered a variety of treatments. Extensive measures to reduce person-to-person transmission of COVID-19 have been implemented to control the current outbreak. Special attention and efforts to protect or reduce transmission should be applied in susceptible populations including children, health care providers, and elderly people. 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Fan</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="review-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Autoimmun</journal-id><journal-id journal-id-type="iso-abbrev">J. Autoimmun</journal-id><journal-title-group><journal-title>Journal of Autoimmunity</journal-title></journal-title-group><issn pub-type="ppub">0896-8411</issn><issn pub-type="epub">1095-9157</issn><publisher><publisher-name>Elsevier Ltd.</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">32113704</article-id><article-id pub-id-type="pmc">7127067</article-id><article-id pub-id-type="publisher-id">S0896-8411(20)30046-9</article-id><article-id pub-id-type="doi">10.1016/j.jaut.2020.102433</article-id><article-id pub-id-type="publisher-id">102433</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak</article-title></title-group><contrib-group><contrib contrib-type="author" id="au1"><name><surname>Rothan</surname><given-names>Hussin A.</given-names></name><email>hrothan@gsu.edu</email><xref rid="aff1" ref-type="aff">a</xref></contrib><contrib contrib-type="author" id="au2"><name><surname>Byrareddy</surname><given-names>Siddappa N.</given-names></name><email>sid.byrareddy@unmc.edu</email><xref rid="aff2" ref-type="aff">b</xref><xref rid="aff3" ref-type="aff">c</xref><xref rid="aff4" ref-type="aff">d</xref><xref rid="cor1" ref-type="corresp">∗</xref></contrib></contrib-group><aff id="aff1"><label>a</label>Department of Biology, College of Arts and Sciences, Georgia State University, Atlanta, GA, USA</aff><aff id="aff2"><label>b</label>Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Centre, Omaha, NE, USA</aff><aff id="aff3"><label>c</label>Department of Genetics, Cell Biology and Anatomy, Omaha, NE, USA</aff><aff id="aff4"><label>d</label>Department of Biochemistry and Molecular Biology, University of Nebraska Medical Centre, Omaha, NE, USA</aff><author-notes><corresp id="cor1"><label>∗</label>Corresponding author. Department of Pharmacology and Experimental Neuroscience Durham Research Center, 8047 985880 Nebraska Medical Center Omaha, NE, 68198-5880, USA <email>sid.byrareddy@unmc.edu</email></corresp></author-notes><pub-date pub-type="pmc-release"><day>26</day><month>2</month><year>2020</year></pub-date><pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><month>5</month><year>2020</year></pub-date><pub-date pub-type="epub"><day>26</day><month>2</month><year>2020</year></pub-date><volume>109</volume><fpage>102433</fpage><lpage>102433</lpage><history><date date-type="received"><day>10</day><month>2</month><year>2020</year></date><date date-type="rev-recd"><day>17</day><month>2</month><year>2020</year></date><date date-type="accepted"><day>18</day><month>2</month><year>2020</year></date></history><permissions><copyright-statement>© 2020 Elsevier Ltd. All rights reserved.</copyright-statement><copyright-year>2020</copyright-year><copyright-holder>Elsevier Ltd</copyright-holder><license><license-p>Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.</license-p></license></permissions><abstract id="abs0010"><p>Coronavirus disease (COVID-19) is caused by SARS-COV2 and represents the causative agent of a potentially fatal disease that is of great global public health concern. Based on the large number of infected people that were exposed to the wet animal market in Wuhan City, China, it is suggested that this is likely the zoonotic origin of COVID-19. Person-to-person transmission of COVID-19 infection led to the isolation of patients that were subsequently administered a variety of treatments. Extensive measures to reduce person-to-person transmission of COVID-19 have been implemented to control the current outbreak. Special attention and efforts to protect or reduce transmission should be applied in susceptible populations including children, health care providers, and elderly people. In this review, we highlights the symptoms, epidemiology, transmission, pathogenesis, phylogenetic analysis and future directions to control the spread of this fatal disease.</p></abstract><abstract abstract-type="author-highlights" id="abs0015"><title>Highlights</title><p><list list-type="simple" id="ulist0010"><list-item id="u0010"><label>•</label><p id="p0010">Coronavirus disease (COVID-19) represents global public health concern and WHO declares public health emergency.</p></list-item><list-item id="u0015"><label>•</label><p id="p0015">The phylogenetic analysis revealed that COVID-19 is potentially a zoonotic virus.</p></list-item><list-item id="u0020"><label>•</label><p id="p0020">Special attention is necessary to protect or reduce transmission in susceptible populations.</p></list-item><list-item id="u0025"><label>•</label><p id="p0025">COVID-19 develop intestinal symptoms like diarrhea, while low percentage of MERS-CoV or SARS-CoV patients had diarrhea.</p></list-item><list-item id="u0030"><label>•</label><p id="p0030">Identification of novel chemotherapeutic drugs for treating COVID-19 infections is urgently warranted.</p></list-item></list></p></abstract><kwd-group id="kwrds0010"><title>Keywords</title><kwd>Coronavirus</kwd><kwd>COVID-19</kwd><kwd>Wuhan city</kwd><kwd>Pneumonia</kwd><kwd>Pathogenesis</kwd></kwd-group></article-meta></front></pmc><affiliations><list><country><li>États-Unis</li></country><region><li>Géorgie (États-Unis)</li><li>Nebraska</li></region></list><tree><country name="États-Unis"><region name="Géorgie (États-Unis)"><name sortKey="Rothan, Hussin A" sort="Rothan, Hussin A" uniqKey="Rothan H" first="Hussin A." last="Rothan">Hussin A. Rothan</name></region><name sortKey="Byrareddy, Siddappa N" sort="Byrareddy, Siddappa N" uniqKey="Byrareddy S" first="Siddappa N." last="Byrareddy">Siddappa N. Byrareddy</name><name sortKey="Byrareddy, Siddappa N" sort="Byrareddy, Siddappa N" uniqKey="Byrareddy S" first="Siddappa N." last="Byrareddy">Siddappa N. Byrareddy</name><name sortKey="Byrareddy, Siddappa N" sort="Byrareddy, Siddappa N" uniqKey="Byrareddy S" first="Siddappa N." last="Byrareddy">Siddappa N. Byrareddy</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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