SrasV1, PascalFrancis, Curation, bibRecord, 000827

Intraspecies diversity of SARS-like coronaviruses in Rhinolophus sinicus and its implications for the origin of SARS coronaviruses in humans

Identifieur interne : 000827 ( PascalFrancis/Curation ); précédent : 000826; suivant : 000828

Intraspecies diversity of SARS-like coronaviruses in Rhinolophus sinicus and its implications for the origin of SARS coronaviruses in humans

Auteurs : JUNFA YUAN [République populaire de Chine] ; Chung-Chau Hon [Hong Kong] ; YAN LI [République populaire de Chine] ; DINGMING WANG [République populaire de Chine] ; GELIN XU [République populaire de Chine] ; HUAJUN ZHANG [République populaire de Chine] ; PENG ZHOU [République populaire de Chine] ; Leo L. M. Poon [Hong Kong] ; Tommy Tsan-Yuk Lam [Hong Kong] ; Frederick Chi-Ching Leung [Hong Kong] ; ZHENGLI SHI [République populaire de Chine]

Source :

Journal of general virology [ 0022-1317 ] ; 2010.

RBID : Pascal:10-0290738

Descripteurs français

Pascal (Inist)
- Virus syndrome respiratoire aigu sévère, Homme, Comparaison intraspécifique, Origine.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Human, Intraspecific comparison, Origin, Severe acute respiratory syndrome virus.

Abstract

The Chinese rufous horseshoe bat (Rhinolophus sinicus) has been suggested to carry the direct ancestor of severe acute respiratory syndrome (SARS) coronavirus (SCoV), and the diversity of SARS-like CoVs (SLCoV) within this Rhinolophus species is therefore worth investigating. Here, we demonstrate the remarkable diversity of SLCoVs in R. sinicus and identify a strain with the same pattern of phylogenetic incongruence (i.e. an indication of recombination) as reported previously in another SLCoV strain. Moreover, this strain possesses a distinctive 579 nt deletion in the nsp3 region that was also found in a human SCoV from the late-phase epidemic. Phylogenetic analysis of the Orf1 region suggested that the human SCoVs are phylogenetically closer to SLCoVs in R. sinicus than to SLCoVs in other Rhinolophus species. These findings reveal a closer evolutionary linkage between SCoV in humans and SLCoVs in R. sinicus, defining the scope of surveillance to search for the direct ancestor of human SCoVs.

A01	`01`	`1`		`@0 0022-1317`
A02	`01`			`@0 JGVIAY`
A03		`1`		`@0 J. gen. virol.`
A05				`@2 91`
A06				`@3 p. 4`
A08	`01`	`1`	`ENG`	`@1 Intraspecies diversity of SARS-like coronaviruses in Rhinolophus sinicus and its implications for the origin of SARS coronaviruses in humans`
A11	`01`	`1`		`@1 JUNFA YUAN`
A11	`02`	`1`		`@1 HON (Chung-Chau)`
A11	`03`	`1`		`@1 YAN LI`
A11	`04`	`1`		`@1 DINGMING WANG`
A11	`05`	`1`		`@1 GELIN XU`
A11	`06`	`1`		`@1 HUAJUN ZHANG`
A11	`07`	`1`		`@1 PENG ZHOU`
A11	`08`	`1`		`@1 POON (Leo L. M.)`
A11	`09`	`1`		`@1 LAM (Tommy Tsan-Yuk)`
A11	`10`	`1`		`@1 LEUNG (Frederick Chi-Ching)`
A11	`11`	`1`		`@1 ZHENGLI SHI`
A14	`01`			`@1 State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences (CAS) @2 Wuhan @3 CHN @Z 1 aut. @Z 3 aut. @Z 6 aut. @Z 7 aut. @Z 11 aut.`
A14	`02`			`@1 School of Biological Sciences, The University of Hong Kong @3 HKG @Z 2 aut. @Z 9 aut. @Z 10 aut.`
A14	`03`			`@1 Disease Control and Prevention of Guizhou Province @2 Guiyang @3 CHN @Z 4 aut.`
A14	`04`			`@1 Wuhan Institute of Biological Products, Ministry of Health @2 Wuhan @3 CHN @Z 5 aut.`
A14	`05`			`@1 Department of Microbiology, The University of Hong Kong @3 HKG @Z 8 aut.`
A20				`@1 1058-1062`
A21				`@1 2010`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 13533 @5 354000181526380260`
A44				`@0 0000 @1 © 2010 INIST-CNRS. All rights reserved.`
A45				`@0 1/2 p.`
A47	`01`	`1`		`@0 10-0290738`
A60				`@1 P @3 CC`
A61				`@0 A`
A64	`01`	`1`		`@0 Journal of general virology`
A66	`01`			`@0 GBR`
C01	`01`		`ENG`	@0 The Chinese rufous horseshoe bat (Rhinolophus sinicus) has been suggested to carry the direct ancestor of severe acute respiratory syndrome (SARS) coronavirus (SCoV), and the diversity of SARS-like CoVs (SLCoV) within this Rhinolophus species is therefore worth investigating. Here, we demonstrate the remarkable diversity of SLCoVs in R. sinicus and identify a strain with the same pattern of phylogenetic incongruence (i.e. an indication of recombination) as reported previously in another SLCoV strain. Moreover, this strain possesses a distinctive 579 nt deletion in the nsp3 region that was also found in a human SCoV from the late-phase epidemic. Phylogenetic analysis of the Orf1 region suggested that the human SCoVs are phylogenetically closer to SLCoVs in R. sinicus than to SLCoVs in other Rhinolophus species. These findings reveal a closer evolutionary linkage between SCoV in humans and SLCoVs in R. sinicus, defining the scope of surveillance to search for the direct ancestor of human SCoVs.
C02	`01`	`X`		`@0 002A05C10`
C03	`01`	`X`	`FRE`	`@0 Virus syndrome respiratoire aigu sévère @2 NW @5 01`
C03	`01`	`X`	`ENG`	`@0 Severe acute respiratory syndrome virus @2 NW @5 01`
C03	`01`	`X`	`SPA`	`@0 Severe acute respiratory syndrome virus @2 NW @5 01`
C03	`02`	`X`	`FRE`	`@0 Homme @5 02`
C03	`02`	`X`	`ENG`	`@0 Human @5 02`
C03	`02`	`X`	`SPA`	`@0 Hombre @5 02`
C03	`03`	`X`	`FRE`	`@0 Comparaison intraspécifique @5 05`
C03	`03`	`X`	`ENG`	`@0 Intraspecific comparison @5 05`
C03	`03`	`X`	`SPA`	`@0 Comparación intraespecífica @5 05`
C03	`04`	`X`	`FRE`	`@0 Origine @5 06`
C03	`04`	`X`	`ENG`	`@0 Origin @5 06`
C03	`04`	`X`	`SPA`	`@0 Origen @5 06`
C07	`01`	`X`	`FRE`	`@0 Coronavirus @2 NW`
C07	`01`	`X`	`ENG`	`@0 Coronavirus @2 NW`
C07	`01`	`X`	`SPA`	`@0 Coronavirus @2 NW`
C07	`02`	`X`	`FRE`	`@0 Coronaviridae @2 NW`
C07	`02`	`X`	`ENG`	`@0 Coronaviridae @2 NW`
C07	`02`	`X`	`SPA`	`@0 Coronaviridae @2 NW`
C07	`03`	`X`	`FRE`	`@0 Nidovirales @2 NW`
C07	`03`	`X`	`ENG`	`@0 Nidovirales @2 NW`
C07	`03`	`X`	`SPA`	`@0 Nidovirales @2 NW`
C07	`04`	`X`	`FRE`	`@0 Virus @2 NW`
C07	`04`	`X`	`ENG`	`@0 Virus @2 NW`
C07	`04`	`X`	`SPA`	`@0 Virus @2 NW`
N21				`@1 186`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

Links toward previous steps (curation, corpus...)

to stream PascalFrancis, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000161

Links to Exploration step

Pascal:10-0290738

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Intraspecies diversity of SARS-like coronaviruses in Rhinolophus sinicus and its implications for the origin of SARS coronaviruses in humans</title>
<author><name sortKey="Junfa Yuan" sort="Junfa Yuan" uniqKey="Junfa Yuan" last="Junfa Yuan">JUNFA YUAN</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences (CAS)</s1>
<s2>Wuhan</s2>
<s3>CHN</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>République populaire de Chine</country>
</affiliation>
</author>
<author><name sortKey="Hon, Chung Chau" sort="Hon, Chung Chau" uniqKey="Hon C" first="Chung-Chau" last="Hon">Chung-Chau Hon</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>School of Biological Sciences, The University of Hong Kong</s1>
<s3>HKG</s3>
<sZ>2 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Hong Kong</country>
</affiliation>
</author>
<author><name sortKey="Yan Li" sort="Yan Li" uniqKey="Yan Li" last="Yan Li">YAN LI</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences (CAS)</s1>
<s2>Wuhan</s2>
<s3>CHN</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>République populaire de Chine</country>
</affiliation>
</author>
<author><name sortKey="Dingming Wang" sort="Dingming Wang" uniqKey="Dingming Wang" last="Dingming Wang">DINGMING WANG</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Disease Control and Prevention of Guizhou Province</s1>
<s2>Guiyang</s2>
<s3>CHN</s3>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>République populaire de Chine</country>
</affiliation>
</author>
<author><name sortKey="Gelin Xu" sort="Gelin Xu" uniqKey="Gelin Xu" last="Gelin Xu">GELIN XU</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Wuhan Institute of Biological Products, Ministry of Health</s1>
<s2>Wuhan</s2>
<s3>CHN</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>République populaire de Chine</country>
</affiliation>
</author>
<author><name sortKey="Huajun Zhang" sort="Huajun Zhang" uniqKey="Huajun Zhang" last="Huajun Zhang">HUAJUN ZHANG</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences (CAS)</s1>
<s2>Wuhan</s2>
<s3>CHN</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>République populaire de Chine</country>
</affiliation>
</author>
<author><name sortKey="Peng Zhou" sort="Peng Zhou" uniqKey="Peng Zhou" last="Peng Zhou">PENG ZHOU</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences (CAS)</s1>
<s2>Wuhan</s2>
<s3>CHN</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>République populaire de Chine</country>
</affiliation>
</author>
<author><name sortKey="Poon, Leo L M" sort="Poon, Leo L M" uniqKey="Poon L" first="Leo L. M." last="Poon">Leo L. M. Poon</name>
<affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Department of Microbiology, The University of Hong Kong</s1>
<s3>HKG</s3>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Hong Kong</country>
</affiliation>
</author>
<author><name sortKey="Lam, Tommy Tsan Yuk" sort="Lam, Tommy Tsan Yuk" uniqKey="Lam T" first="Tommy Tsan-Yuk" last="Lam">Tommy Tsan-Yuk Lam</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>School of Biological Sciences, The University of Hong Kong</s1>
<s3>HKG</s3>
<sZ>2 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Hong Kong</country>
</affiliation>
</author>
<author><name sortKey="Leung, Frederick Chi Ching" sort="Leung, Frederick Chi Ching" uniqKey="Leung F" first="Frederick Chi-Ching" last="Leung">Frederick Chi-Ching Leung</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>School of Biological Sciences, The University of Hong Kong</s1>
<s3>HKG</s3>
<sZ>2 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Hong Kong</country>
</affiliation>
</author>
<author><name sortKey="Zhengli Shi" sort="Zhengli Shi" uniqKey="Zhengli Shi" last="Zhengli Shi">ZHENGLI SHI</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences (CAS)</s1>
<s2>Wuhan</s2>
<s3>CHN</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>République populaire de Chine</country>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">10-0290738</idno>
<date when="2010">2010</date>
<idno type="stanalyst">PASCAL 10-0290738 INIST</idno>
<idno type="RBID">Pascal:10-0290738</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000161</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000827</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Intraspecies diversity of SARS-like coronaviruses in Rhinolophus sinicus and its implications for the origin of SARS coronaviruses in humans</title>
<author><name sortKey="Junfa Yuan" sort="Junfa Yuan" uniqKey="Junfa Yuan" last="Junfa Yuan">JUNFA YUAN</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences (CAS)</s1>
<s2>Wuhan</s2>
<s3>CHN</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>République populaire de Chine</country>
</affiliation>
</author>
<author><name sortKey="Hon, Chung Chau" sort="Hon, Chung Chau" uniqKey="Hon C" first="Chung-Chau" last="Hon">Chung-Chau Hon</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>School of Biological Sciences, The University of Hong Kong</s1>
<s3>HKG</s3>
<sZ>2 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Hong Kong</country>
</affiliation>
</author>
<author><name sortKey="Yan Li" sort="Yan Li" uniqKey="Yan Li" last="Yan Li">YAN LI</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences (CAS)</s1>
<s2>Wuhan</s2>
<s3>CHN</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>République populaire de Chine</country>
</affiliation>
</author>
<author><name sortKey="Dingming Wang" sort="Dingming Wang" uniqKey="Dingming Wang" last="Dingming Wang">DINGMING WANG</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Disease Control and Prevention of Guizhou Province</s1>
<s2>Guiyang</s2>
<s3>CHN</s3>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>République populaire de Chine</country>
</affiliation>
</author>
<author><name sortKey="Gelin Xu" sort="Gelin Xu" uniqKey="Gelin Xu" last="Gelin Xu">GELIN XU</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Wuhan Institute of Biological Products, Ministry of Health</s1>
<s2>Wuhan</s2>
<s3>CHN</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>République populaire de Chine</country>
</affiliation>
</author>
<author><name sortKey="Huajun Zhang" sort="Huajun Zhang" uniqKey="Huajun Zhang" last="Huajun Zhang">HUAJUN ZHANG</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences (CAS)</s1>
<s2>Wuhan</s2>
<s3>CHN</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>République populaire de Chine</country>
</affiliation>
</author>
<author><name sortKey="Peng Zhou" sort="Peng Zhou" uniqKey="Peng Zhou" last="Peng Zhou">PENG ZHOU</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences (CAS)</s1>
<s2>Wuhan</s2>
<s3>CHN</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>République populaire de Chine</country>
</affiliation>
</author>
<author><name sortKey="Poon, Leo L M" sort="Poon, Leo L M" uniqKey="Poon L" first="Leo L. M." last="Poon">Leo L. M. Poon</name>
<affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Department of Microbiology, The University of Hong Kong</s1>
<s3>HKG</s3>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>Hong Kong</country>
</affiliation>
</author>
<author><name sortKey="Lam, Tommy Tsan Yuk" sort="Lam, Tommy Tsan Yuk" uniqKey="Lam T" first="Tommy Tsan-Yuk" last="Lam">Tommy Tsan-Yuk Lam</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>School of Biological Sciences, The University of Hong Kong</s1>
<s3>HKG</s3>
<sZ>2 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Hong Kong</country>
</affiliation>
</author>
<author><name sortKey="Leung, Frederick Chi Ching" sort="Leung, Frederick Chi Ching" uniqKey="Leung F" first="Frederick Chi-Ching" last="Leung">Frederick Chi-Ching Leung</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>School of Biological Sciences, The University of Hong Kong</s1>
<s3>HKG</s3>
<sZ>2 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>Hong Kong</country>
</affiliation>
</author>
<author><name sortKey="Zhengli Shi" sort="Zhengli Shi" uniqKey="Zhengli Shi" last="Zhengli Shi">ZHENGLI SHI</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences (CAS)</s1>
<s2>Wuhan</s2>
<s3>CHN</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>République populaire de Chine</country>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Journal of general virology</title>
<title level="j" type="abbreviated">J. gen. virol.</title>
<idno type="ISSN">0022-1317</idno>
<imprint><date when="2010">2010</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Journal of general virology</title>
<title level="j" type="abbreviated">J. gen. virol.</title>
<idno type="ISSN">0022-1317</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Human</term>
<term>Intraspecific comparison</term>
<term>Origin</term>
<term>Severe acute respiratory syndrome virus</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Virus syndrome respiratoire aigu sévère</term>
<term>Homme</term>
<term>Comparaison intraspécifique</term>
<term>Origine</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The Chinese rufous horseshoe bat (Rhinolophus sinicus) has been suggested to carry the direct ancestor of severe acute respiratory syndrome (SARS) coronavirus (SCoV), and the diversity of SARS-like CoVs (SLCoV) within this Rhinolophus species is therefore worth investigating. Here, we demonstrate the remarkable diversity of SLCoVs in R. sinicus and identify a strain with the same pattern of phylogenetic incongruence (i.e. an indication of recombination) as reported previously in another SLCoV strain. Moreover, this strain possesses a distinctive 579 nt deletion in the nsp3 region that was also found in a human SCoV from the late-phase epidemic. Phylogenetic analysis of the Orf1 region suggested that the human SCoVs are phylogenetically closer to SLCoVs in R. sinicus than to SLCoVs in other Rhinolophus species. These findings reveal a closer evolutionary linkage between SCoV in humans and SLCoVs in R. sinicus, defining the scope of surveillance to search for the direct ancestor of human SCoVs.</div>
</front>
</TEI>
<inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0022-1317</s0>
</fA01>
<fA02 i1="01"><s0>JGVIAY</s0>
</fA02>
<fA03 i2="1"><s0>J. gen. virol.</s0>
</fA03>
<fA05><s2>91</s2>
</fA05>
<fA06><s3>p. 4</s3>
</fA06>
<fA08 i1="01" i2="1" l="ENG"><s1>Intraspecies diversity of SARS-like coronaviruses in Rhinolophus sinicus and its implications for the origin of SARS coronaviruses in humans</s1>
</fA08>
<fA11 i1="01" i2="1"><s1>JUNFA YUAN</s1>
</fA11>
<fA11 i1="02" i2="1"><s1>HON (Chung-Chau)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>YAN LI</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>DINGMING WANG</s1>
</fA11>
<fA11 i1="05" i2="1"><s1>GELIN XU</s1>
</fA11>
<fA11 i1="06" i2="1"><s1>HUAJUN ZHANG</s1>
</fA11>
<fA11 i1="07" i2="1"><s1>PENG ZHOU</s1>
</fA11>
<fA11 i1="08" i2="1"><s1>POON (Leo L. M.)</s1>
</fA11>
<fA11 i1="09" i2="1"><s1>LAM (Tommy Tsan-Yuk)</s1>
</fA11>
<fA11 i1="10" i2="1"><s1>LEUNG (Frederick Chi-Ching)</s1>
</fA11>
<fA11 i1="11" i2="1"><s1>ZHENGLI SHI</s1>
</fA11>
<fA14 i1="01"><s1>State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences (CAS)</s1>
<s2>Wuhan</s2>
<s3>CHN</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>11 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>School of Biological Sciences, The University of Hong Kong</s1>
<s3>HKG</s3>
<sZ>2 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>Disease Control and Prevention of Guizhou Province</s1>
<s2>Guiyang</s2>
<s3>CHN</s3>
<sZ>4 aut.</sZ>
</fA14>
<fA14 i1="04"><s1>Wuhan Institute of Biological Products, Ministry of Health</s1>
<s2>Wuhan</s2>
<s3>CHN</s3>
<sZ>5 aut.</sZ>
</fA14>
<fA14 i1="05"><s1>Department of Microbiology, The University of Hong Kong</s1>
<s3>HKG</s3>
<sZ>8 aut.</sZ>
</fA14>
<fA20><s1>1058-1062</s1>
</fA20>
<fA21><s1>2010</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
<fA43 i1="01"><s1>INIST</s1>
<s2>13533</s2>
<s5>354000181526380260</s5>
</fA43>
<fA44><s0>0000</s0>
<s1>© 2010 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45><s0>1/2 p.</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>10-0290738</s0>
</fA47>
<fA60><s1>P</s1>
<s3>CC</s3>
</fA60>
<fA61><s0>A</s0>
</fA61>
<fA64 i1="01" i2="1"><s0>Journal of general virology</s0>
</fA64>
<fA66 i1="01"><s0>GBR</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>The Chinese rufous horseshoe bat (Rhinolophus sinicus) has been suggested to carry the direct ancestor of severe acute respiratory syndrome (SARS) coronavirus (SCoV), and the diversity of SARS-like CoVs (SLCoV) within this Rhinolophus species is therefore worth investigating. Here, we demonstrate the remarkable diversity of SLCoVs in R. sinicus and identify a strain with the same pattern of phylogenetic incongruence (i.e. an indication of recombination) as reported previously in another SLCoV strain. Moreover, this strain possesses a distinctive 579 nt deletion in the nsp3 region that was also found in a human SCoV from the late-phase epidemic. Phylogenetic analysis of the Orf1 region suggested that the human SCoVs are phylogenetically closer to SLCoVs in R. sinicus than to SLCoVs in other Rhinolophus species. These findings reveal a closer evolutionary linkage between SCoV in humans and SLCoVs in R. sinicus, defining the scope of surveillance to search for the direct ancestor of human SCoVs.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002A05C10</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Virus syndrome respiratoire aigu sévère</s0>
<s2>NW</s2>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Severe acute respiratory syndrome virus</s0>
<s2>NW</s2>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Severe acute respiratory syndrome virus</s0>
<s2>NW</s2>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Homme</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Human</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Hombre</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Comparaison intraspécifique</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Intraspecific comparison</s0>
<s5>05</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Comparación intraespecífica</s0>
<s5>05</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Origine</s0>
<s5>06</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Origin</s0>
<s5>06</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Origen</s0>
<s5>06</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Coronavirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Coronavirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Coronavirus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Coronaviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Coronaviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Coronaviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Nidovirales</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Nidovirales</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Nidovirales</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fN21><s1>186</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
</standard>
</inist>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/PascalFrancis/Curation

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000827 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Curation/biblio.hfd -nk 000827 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    SrasV1
   |flux=    PascalFrancis
   |étape=   Curation
   |type=    RBID
   |clé=     Pascal:10-0290738
   |texte=   Intraspecies diversity of SARS-like coronaviruses in Rhinolophus sinicus and its implications for the origin of SARS coronaviruses in humans
}}

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 28 14:49:16 2020. Site generation: Sat Mar 27 22:06:49 2021

	Serveur d'exploration SRAS
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration SRAS

Intraspecies diversity of SARS-like coronaviruses in Rhinolophus sinicus and its implications for the origin of SARS coronaviruses in humans

Intraspecies diversity of SARS-like coronaviruses in Rhinolophus sinicus and its implications for the origin of SARS coronaviruses in humans

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri