SrasV1, PascalFrancis, Corpus, bibRecord, 000815

New point of care test is highly specific but less sensitive for influenza virus A and B in children and adults

Identifieur interne : 000815 ( PascalFrancis/Corpus ); précédent : 000814; suivant : 000816

New point of care test is highly specific but less sensitive for influenza virus A and B in children and adults

Auteurs : William D. Rawlinson ; Zubair M. Waliuzzaman ; Michael Fennell ; James R. Appleman ; Craig D. Shimasaki ; Ian W. Carter

Source :

Journal of medical virology [ 0146-6615 ] ; 2004.

RBID : Pascal:04-0484135

Descripteurs français

Pascal (Inist)
- Influenzavirus, Virus grippal A, Virus grippal B, Grippe A, Grippe B, Enfant, Adulte, Grave, Malade état grave, Aigu, Voie respiratoire, Syndrome respiratoire aigu sévère, Traitement, Diagnostic, Forme grave.

English descriptors

KwdEn :
- Acute, Adult, Child, Critically ill, Diagnosis, Influenza A, Influenza A virus, Influenza B, Influenza B virus, Influenzavirus, Respiratory tract, Severe, Severe acute respiratory syndrome, Treatment.

Abstract

The importance of rapid diagnosis of influenza has increased with the availability of neuraminidase inhibitors, which need to be commenced within 48 hr of symptom onset. Furthermore, the recent development of influenza-like clinical syndromes with novel aetiologies (severe acute respiratory syndrome, SARS) has increased the need for rapid and accurate near-patient diagnosis. A new, modified point of care (POC) diagnostic test (ZstatFlu) was assessed on 469 nasopharyngeal aspirates (NPAs) and 260 nose/ throat swabs (TS) taken from children and adults. The test was specific (77-98%) for all specimen types for influenza virus A and B, depending upon incubation conditions. However, it was less sensitive, detecting 65-77% of specimens confirmed as positive on culture, direct immunofluorescence or PCR testing. A positive test is useful, for both directing initiation of therapy in the clinician's office, and making a positive diagnosis of influenza in patients with influenza-like clinical syndromes.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A02	`01`			`@0 JMVIDB`
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A05				`@2 74`
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A08	`01`	`1`	`ENG`	`@1 New point of care test is highly specific but less sensitive for influenza virus A and B in children and adults`
A11	`01`	`1`		`@1 RAWLINSON (William D.)`
A11	`02`	`1`		`@1 WALIUZZAMAN (Zubair M.)`
A11	`03`	`1`		`@1 FENNELL (Michael)`
A11	`04`	`1`		`@1 APPLEMAN (James R.)`
A11	`05`	`1`		`@1 SHIMASAKI (Craig D.)`
A11	`06`	`1`		`@1 CARTER (Ian W.)`
A14	`01`			`@1 Virology Division, Department of Microbiology, SEALS, The Prince of Wales Hospital @3 AUS @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 6 aut.`
A14	`02`			`@1 School of Medical and School of Biotechnology and Biomolecular Sciences, University of New South Wales @2 Kensington, Sydney @3 AUS @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 6 aut.`
A14	`03`			`@1 ZymeTx, Inc. @2 Oklahoma City, Oklahoma @3 USA @Z 4 aut. @Z 5 aut.`
A20				`@1 127-131`
A21				`@1 2004`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 17422 @5 354000113820670180`
A44				`@0 0000 @1 © 2004 INIST-CNRS. All rights reserved.`
A45				`@0 31 ref.`
A47	`01`	`1`		`@0 04-0484135`
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A66	`01`			`@0 USA`
C01	`01`		`ENG`	@0 The importance of rapid diagnosis of influenza has increased with the availability of neuraminidase inhibitors, which need to be commenced within 48 hr of symptom onset. Furthermore, the recent development of influenza-like clinical syndromes with novel aetiologies (severe acute respiratory syndrome, SARS) has increased the need for rapid and accurate near-patient diagnosis. A new, modified point of care (POC) diagnostic test (ZstatFlu) was assessed on 469 nasopharyngeal aspirates (NPAs) and 260 nose/ throat swabs (TS) taken from children and adults. The test was specific (77-98%) for all specimen types for influenza virus A and B, depending upon incubation conditions. However, it was less sensitive, detecting 65-77% of specimens confirmed as positive on culture, direct immunofluorescence or PCR testing. A positive test is useful, for both directing initiation of therapy in the clinician's office, and making a positive diagnosis of influenza in patients with influenza-like clinical syndromes.
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C03	`01`	`X`	`SPA`	`@0 Influenzavirus @2 NW @5 01`
C03	`02`	`X`	`FRE`	`@0 Virus grippal A @2 NW @5 02`
C03	`02`	`X`	`ENG`	`@0 Influenza A virus @2 NW @5 02`
C03	`02`	`X`	`SPA`	`@0 Influenza A virus @2 NW @5 02`
C03	`03`	`X`	`FRE`	`@0 Virus grippal B @2 NW @5 03`
C03	`03`	`X`	`ENG`	`@0 Influenza B virus @2 NW @5 03`
C03	`03`	`X`	`SPA`	`@0 Influenza B virus @2 NW @5 03`
C03	`04`	`X`	`FRE`	`@0 Grippe A @5 05`
C03	`04`	`X`	`ENG`	`@0 Influenza A @5 05`
C03	`04`	`X`	`SPA`	`@0 Gripe A @5 05`
C03	`05`	`X`	`FRE`	`@0 Grippe B @5 06`
C03	`05`	`X`	`ENG`	`@0 Influenza B @5 06`
C03	`05`	`X`	`SPA`	`@0 Gripe B @5 06`
C03	`06`	`X`	`FRE`	`@0 Enfant @5 07`
C03	`06`	`X`	`ENG`	`@0 Child @5 07`
C03	`06`	`X`	`SPA`	`@0 Niño @5 07`
C03	`07`	`X`	`FRE`	`@0 Adulte @5 08`
C03	`07`	`X`	`ENG`	`@0 Adult @5 08`
C03	`07`	`X`	`SPA`	`@0 Adulto @5 08`
C03	`08`	`X`	`FRE`	`@0 Grave @5 09`
C03	`08`	`X`	`ENG`	`@0 Severe @5 09`
C03	`08`	`X`	`SPA`	`@0 Grave @5 09`
C03	`09`	`X`	`FRE`	`@0 Malade état grave @5 10`
C03	`09`	`X`	`ENG`	`@0 Critically ill @5 10`
C03	`09`	`X`	`SPA`	`@0 Enfermo estado grave @5 10`
C03	`10`	`X`	`FRE`	`@0 Aigu @5 11`
C03	`10`	`X`	`ENG`	`@0 Acute @5 11`
C03	`10`	`X`	`SPA`	`@0 Agudo @5 11`
C03	`11`	`X`	`FRE`	`@0 Voie respiratoire @5 12`
C03	`11`	`X`	`ENG`	`@0 Respiratory tract @5 12`
C03	`11`	`X`	`SPA`	`@0 Vía respiratoria @5 12`
C03	`12`	`X`	`FRE`	`@0 Syndrome respiratoire aigu sévère @2 NM @5 14`
C03	`12`	`X`	`ENG`	`@0 Severe acute respiratory syndrome @2 NM @5 14`
C03	`12`	`X`	`SPA`	`@0 Síndrome respiratorio agudo severo @2 NM @5 14`
C03	`13`	`X`	`FRE`	`@0 Traitement @5 67`
C03	`13`	`X`	`ENG`	`@0 Treatment @5 67`
C03	`13`	`X`	`SPA`	`@0 Tratamiento @5 67`
C03	`14`	`X`	`FRE`	`@0 Diagnostic @5 68`
C03	`14`	`X`	`ENG`	`@0 Diagnosis @5 68`
C03	`14`	`X`	`SPA`	`@0 Diagnóstico @5 68`
C03	`15`	`X`	`FRE`	`@0 Forme grave @4 INC @5 79`
C07	`01`	`X`	`FRE`	`@0 Orthomyxoviridae @2 NW`
C07	`01`	`X`	`ENG`	`@0 Orthomyxoviridae @2 NW`
C07	`01`	`X`	`SPA`	`@0 Orthomyxoviridae @2 NW`
C07	`02`	`X`	`FRE`	`@0 Virus @2 NW`
C07	`02`	`X`	`ENG`	`@0 Virus @2 NW`
C07	`02`	`X`	`SPA`	`@0 Virus @2 NW`
C07	`03`	`X`	`FRE`	`@0 Influenzavirus A @2 NW`
C07	`03`	`X`	`ENG`	`@0 Influenzavirus A @2 NW`
C07	`03`	`X`	`SPA`	`@0 Influenzavirus A @2 NW`
C07	`04`	`X`	`FRE`	`@0 Influenzavirus B @2 NW`
C07	`04`	`X`	`ENG`	`@0 Influenzavirus B @2 NW`
C07	`04`	`X`	`SPA`	`@0 Influenzavirus B @2 NW`
C07	`05`	`X`	`FRE`	`@0 Virose @2 NM`
C07	`05`	`X`	`ENG`	`@0 Viral disease @2 NM`
C07	`05`	`X`	`SPA`	`@0 Virosis @2 NM`
C07	`06`	`X`	`FRE`	`@0 Infection @2 NM`
C07	`06`	`X`	`ENG`	`@0 Infection @2 NM`
C07	`06`	`X`	`SPA`	`@0 Infección @2 NM`
C07	`07`	`X`	`FRE`	`@0 Homme`
C07	`07`	`X`	`ENG`	`@0 Human`
C07	`07`	`X`	`SPA`	`@0 Hombre`
C07	`08`	`X`	`FRE`	`@0 Appareil respiratoire pathologie @5 19`
C07	`08`	`X`	`ENG`	`@0 Respiratory disease @5 19`
C07	`08`	`X`	`SPA`	`@0 Aparato respiratorio patología @5 19`
C07	`09`	`X`	`FRE`	`@0 Poumon pathologie @5 20`
C07	`09`	`X`	`ENG`	`@0 Lung disease @5 20`
C07	`09`	`X`	`SPA`	`@0 Pulmón patología @5 20`
C07	`10`	`X`	`FRE`	`@0 Appareil respiratoire @5 22`
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N21				`@1 271`

Format Inist (serveur)

NO :	PASCAL 04-0484135 INIST
ET :	New point of care test is highly specific but less sensitive for influenza virus A and B in children and adults
AU :	RAWLINSON (William D.); WALIUZZAMAN (Zubair M.); FENNELL (Michael); APPLEMAN (James R.); SHIMASAKI (Craig D.); CARTER (Ian W.)
AF :	Virology Division, Department of Microbiology, SEALS, The Prince of Wales Hospital/Australie (1 aut., 2 aut., 3 aut., 6 aut.); School of Medical and School of Biotechnology and Biomolecular Sciences, University of New South Wales/Kensington, Sydney/Australie (1 aut., 2 aut., 3 aut., 6 aut.); ZymeTx, Inc./Oklahoma City, Oklahoma/Etats-Unis (4 aut., 5 aut.)
DT :	Publication en série; Niveau analytique
SO :	Journal of medical virology; ISSN 0146-6615; Coden JMVIDB; Etats-Unis; Da. 2004; Vol. 74; No. 1; Pp. 127-131; Bibl. 31 ref.
LA :	Anglais
EA :	The importance of rapid diagnosis of influenza has increased with the availability of neuraminidase inhibitors, which need to be commenced within 48 hr of symptom onset. Furthermore, the recent development of influenza-like clinical syndromes with novel aetiologies (severe acute respiratory syndrome, SARS) has increased the need for rapid and accurate near-patient diagnosis. A new, modified point of care (POC) diagnostic test (ZstatFlu) was assessed on 469 nasopharyngeal aspirates (NPAs) and 260 nose/ throat swabs (TS) taken from children and adults. The test was specific (77-98%) for all specimen types for influenza virus A and B, depending upon incubation conditions. However, it was less sensitive, detecting 65-77% of specimens confirmed as positive on culture, direct immunofluorescence or PCR testing. A positive test is useful, for both directing initiation of therapy in the clinician's office, and making a positive diagnosis of influenza in patients with influenza-like clinical syndromes.
CC :	002A05C10; 002B05C02J
FD :	Influenzavirus; Virus grippal A; Virus grippal B; Grippe A; Grippe B; Enfant; Adulte; Grave; Malade état grave; Aigu; Voie respiratoire; Syndrome respiratoire aigu sévère; Traitement; Diagnostic; Forme grave
FG :	Orthomyxoviridae; Virus; Influenzavirus A; Influenzavirus B; Virose; Infection; Homme; Appareil respiratoire pathologie; Poumon pathologie; Appareil respiratoire
ED :	Influenzavirus; Influenza A virus; Influenza B virus; Influenza A; Influenza B; Child; Adult; Severe; Critically ill; Acute; Respiratory tract; Severe acute respiratory syndrome; Treatment; Diagnosis
EG :	Orthomyxoviridae; Virus; Influenzavirus A; Influenzavirus B; Viral disease; Infection; Human; Respiratory disease; Lung disease; Respiratory system
SD :	Influenzavirus; Influenza A virus; Influenza B virus; Gripe A; Gripe B; Niño; Adulto; Grave; Enfermo estado grave; Agudo; Vía respiratoria; Síndrome respiratorio agudo severo; Tratamiento; Diagnóstico
LO :	INIST-17422.354000113820670180
ID :	04-0484135

Links to Exploration step

Pascal:04-0484135

Le document en format XML

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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acute</term>
<term>Adult</term>
<term>Child</term>
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<term>Diagnosis</term>
<term>Influenza A</term>
<term>Influenza A virus</term>
<term>Influenza B</term>
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<term>Respiratory tract</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Influenzavirus</term>
<term>Virus grippal A</term>
<term>Virus grippal B</term>
<term>Grippe A</term>
<term>Grippe B</term>
<term>Enfant</term>
<term>Adulte</term>
<term>Grave</term>
<term>Malade état grave</term>
<term>Aigu</term>
<term>Voie respiratoire</term>
<term>Syndrome respiratoire aigu sévère</term>
<term>Traitement</term>
<term>Diagnostic</term>
<term>Forme grave</term>
</keywords>
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<front><div type="abstract" xml:lang="en">The importance of rapid diagnosis of influenza has increased with the availability of neuraminidase inhibitors, which need to be commenced within 48 hr of symptom onset. Furthermore, the recent development of influenza-like clinical syndromes with novel aetiologies (severe acute respiratory syndrome, SARS) has increased the need for rapid and accurate near-patient diagnosis. A new, modified point of care (POC) diagnostic test (ZstatFlu) was assessed on 469 nasopharyngeal aspirates (NPAs) and 260 nose/ throat swabs (TS) taken from children and adults. The test was specific (77-98%) for all specimen types for influenza virus A and B, depending upon incubation conditions. However, it was less sensitive, detecting 65-77% of specimens confirmed as positive on culture, direct immunofluorescence or PCR testing. A positive test is useful, for both directing initiation of therapy in the clinician's office, and making a positive diagnosis of influenza in patients with influenza-like clinical syndromes.</div>
</front>
</TEI>
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</fA01>
<fA02 i1="01"><s0>JMVIDB</s0>
</fA02>
<fA03 i2="1"><s0>J. med. virol.</s0>
</fA03>
<fA05><s2>74</s2>
</fA05>
<fA06><s2>1</s2>
</fA06>
<fA08 i1="01" i2="1" l="ENG"><s1>New point of care test is highly specific but less sensitive for influenza virus A and B in children and adults</s1>
</fA08>
<fA11 i1="01" i2="1"><s1>RAWLINSON (William D.)</s1>
</fA11>
<fA11 i1="02" i2="1"><s1>WALIUZZAMAN (Zubair M.)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>FENNELL (Michael)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>APPLEMAN (James R.)</s1>
</fA11>
<fA11 i1="05" i2="1"><s1>SHIMASAKI (Craig D.)</s1>
</fA11>
<fA11 i1="06" i2="1"><s1>CARTER (Ian W.)</s1>
</fA11>
<fA14 i1="01"><s1>Virology Division, Department of Microbiology, SEALS, The Prince of Wales Hospital</s1>
<s3>AUS</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>School of Medical and School of Biotechnology and Biomolecular Sciences, University of New South Wales</s1>
<s2>Kensington, Sydney</s2>
<s3>AUS</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>ZymeTx, Inc.</s1>
<s2>Oklahoma City, Oklahoma</s2>
<s3>USA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
</fA14>
<fA20><s1>127-131</s1>
</fA20>
<fA21><s1>2004</s1>
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<fA23 i1="01"><s0>ENG</s0>
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<s2>17422</s2>
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<s1>© 2004 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45><s0>31 ref.</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>04-0484135</s0>
</fA47>
<fA60><s1>P</s1>
</fA60>
<fA61><s0>A</s0>
</fA61>
<fA64 i1="01" i2="1"><s0>Journal of medical virology</s0>
</fA64>
<fA66 i1="01"><s0>USA</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>The importance of rapid diagnosis of influenza has increased with the availability of neuraminidase inhibitors, which need to be commenced within 48 hr of symptom onset. Furthermore, the recent development of influenza-like clinical syndromes with novel aetiologies (severe acute respiratory syndrome, SARS) has increased the need for rapid and accurate near-patient diagnosis. A new, modified point of care (POC) diagnostic test (ZstatFlu) was assessed on 469 nasopharyngeal aspirates (NPAs) and 260 nose/ throat swabs (TS) taken from children and adults. The test was specific (77-98%) for all specimen types for influenza virus A and B, depending upon incubation conditions. However, it was less sensitive, detecting 65-77% of specimens confirmed as positive on culture, direct immunofluorescence or PCR testing. A positive test is useful, for both directing initiation of therapy in the clinician's office, and making a positive diagnosis of influenza in patients with influenza-like clinical syndromes.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002A05C10</s0>
</fC02>
<fC02 i1="02" i2="X"><s0>002B05C02J</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Influenzavirus</s0>
<s2>NW</s2>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Influenzavirus</s0>
<s2>NW</s2>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Influenzavirus</s0>
<s2>NW</s2>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Virus grippal A</s0>
<s2>NW</s2>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Influenza A virus</s0>
<s2>NW</s2>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Influenza A virus</s0>
<s2>NW</s2>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Virus grippal B</s0>
<s2>NW</s2>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Influenza B virus</s0>
<s2>NW</s2>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Influenza B virus</s0>
<s2>NW</s2>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Grippe A</s0>
<s5>05</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Influenza A</s0>
<s5>05</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Gripe A</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Grippe B</s0>
<s5>06</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Influenza B</s0>
<s5>06</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Gripe B</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Enfant</s0>
<s5>07</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Child</s0>
<s5>07</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Niño</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Adulte</s0>
<s5>08</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Adult</s0>
<s5>08</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Adulto</s0>
<s5>08</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Grave</s0>
<s5>09</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Severe</s0>
<s5>09</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Grave</s0>
<s5>09</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Malade état grave</s0>
<s5>10</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Critically ill</s0>
<s5>10</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Enfermo estado grave</s0>
<s5>10</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE"><s0>Aigu</s0>
<s5>11</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG"><s0>Acute</s0>
<s5>11</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Agudo</s0>
<s5>11</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE"><s0>Voie respiratoire</s0>
<s5>12</s5>
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<fC03 i1="11" i2="X" l="ENG"><s0>Respiratory tract</s0>
<s5>12</s5>
</fC03>
<fC03 i1="11" i2="X" l="SPA"><s0>Vía respiratoria</s0>
<s5>12</s5>
</fC03>
<fC03 i1="12" i2="X" l="FRE"><s0>Syndrome respiratoire aigu sévère</s0>
<s2>NM</s2>
<s5>14</s5>
</fC03>
<fC03 i1="12" i2="X" l="ENG"><s0>Severe acute respiratory syndrome</s0>
<s2>NM</s2>
<s5>14</s5>
</fC03>
<fC03 i1="12" i2="X" l="SPA"><s0>Síndrome respiratorio agudo severo</s0>
<s2>NM</s2>
<s5>14</s5>
</fC03>
<fC03 i1="13" i2="X" l="FRE"><s0>Traitement</s0>
<s5>67</s5>
</fC03>
<fC03 i1="13" i2="X" l="ENG"><s0>Treatment</s0>
<s5>67</s5>
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<fC03 i1="13" i2="X" l="SPA"><s0>Tratamiento</s0>
<s5>67</s5>
</fC03>
<fC03 i1="14" i2="X" l="FRE"><s0>Diagnostic</s0>
<s5>68</s5>
</fC03>
<fC03 i1="14" i2="X" l="ENG"><s0>Diagnosis</s0>
<s5>68</s5>
</fC03>
<fC03 i1="14" i2="X" l="SPA"><s0>Diagnóstico</s0>
<s5>68</s5>
</fC03>
<fC03 i1="15" i2="X" l="FRE"><s0>Forme grave</s0>
<s4>INC</s4>
<s5>79</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Orthomyxoviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Orthomyxoviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Orthomyxoviridae</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Influenzavirus A</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Influenzavirus A</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Influenzavirus A</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Influenzavirus B</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Influenzavirus B</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Influenzavirus B</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Virose</s0>
<s2>NM</s2>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Viral disease</s0>
<s2>NM</s2>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Virosis</s0>
<s2>NM</s2>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Infection</s0>
<s2>NM</s2>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Infection</s0>
<s2>NM</s2>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Infección</s0>
<s2>NM</s2>
</fC07>
<fC07 i1="07" i2="X" l="FRE"><s0>Homme</s0>
</fC07>
<fC07 i1="07" i2="X" l="ENG"><s0>Human</s0>
</fC07>
<fC07 i1="07" i2="X" l="SPA"><s0>Hombre</s0>
</fC07>
<fC07 i1="08" i2="X" l="FRE"><s0>Appareil respiratoire pathologie</s0>
<s5>19</s5>
</fC07>
<fC07 i1="08" i2="X" l="ENG"><s0>Respiratory disease</s0>
<s5>19</s5>
</fC07>
<fC07 i1="08" i2="X" l="SPA"><s0>Aparato respiratorio patología</s0>
<s5>19</s5>
</fC07>
<fC07 i1="09" i2="X" l="FRE"><s0>Poumon pathologie</s0>
<s5>20</s5>
</fC07>
<fC07 i1="09" i2="X" l="ENG"><s0>Lung disease</s0>
<s5>20</s5>
</fC07>
<fC07 i1="09" i2="X" l="SPA"><s0>Pulmón patología</s0>
<s5>20</s5>
</fC07>
<fC07 i1="10" i2="X" l="FRE"><s0>Appareil respiratoire</s0>
<s5>22</s5>
</fC07>
<fC07 i1="10" i2="X" l="ENG"><s0>Respiratory system</s0>
<s5>22</s5>
</fC07>
<fC07 i1="10" i2="X" l="SPA"><s0>Aparato respiratorio</s0>
<s5>22</s5>
</fC07>
<fN21><s1>271</s1>
</fN21>
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<server><NO>PASCAL 04-0484135 INIST</NO>
<ET>New point of care test is highly specific but less sensitive for influenza virus A and B in children and adults</ET>
<AU>RAWLINSON (William D.); WALIUZZAMAN (Zubair M.); FENNELL (Michael); APPLEMAN (James R.); SHIMASAKI (Craig D.); CARTER (Ian W.)</AU>
<AF>Virology Division, Department of Microbiology, SEALS, The Prince of Wales Hospital/Australie (1 aut., 2 aut., 3 aut., 6 aut.); School of Medical and School of Biotechnology and Biomolecular Sciences, University of New South Wales/Kensington, Sydney/Australie (1 aut., 2 aut., 3 aut., 6 aut.); ZymeTx, Inc./Oklahoma City, Oklahoma/Etats-Unis (4 aut., 5 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Journal of medical virology; ISSN 0146-6615; Coden JMVIDB; Etats-Unis; Da. 2004; Vol. 74; No. 1; Pp. 127-131; Bibl. 31 ref.</SO>
<LA>Anglais</LA>
<EA>The importance of rapid diagnosis of influenza has increased with the availability of neuraminidase inhibitors, which need to be commenced within 48 hr of symptom onset. Furthermore, the recent development of influenza-like clinical syndromes with novel aetiologies (severe acute respiratory syndrome, SARS) has increased the need for rapid and accurate near-patient diagnosis. A new, modified point of care (POC) diagnostic test (ZstatFlu) was assessed on 469 nasopharyngeal aspirates (NPAs) and 260 nose/ throat swabs (TS) taken from children and adults. The test was specific (77-98%) for all specimen types for influenza virus A and B, depending upon incubation conditions. However, it was less sensitive, detecting 65-77% of specimens confirmed as positive on culture, direct immunofluorescence or PCR testing. A positive test is useful, for both directing initiation of therapy in the clinician's office, and making a positive diagnosis of influenza in patients with influenza-like clinical syndromes.</EA>
<CC>002A05C10; 002B05C02J</CC>
<FD>Influenzavirus; Virus grippal A; Virus grippal B; Grippe A; Grippe B; Enfant; Adulte; Grave; Malade état grave; Aigu; Voie respiratoire; Syndrome respiratoire aigu sévère; Traitement; Diagnostic; Forme grave</FD>
<FG>Orthomyxoviridae; Virus; Influenzavirus A; Influenzavirus B; Virose; Infection; Homme; Appareil respiratoire pathologie; Poumon pathologie; Appareil respiratoire</FG>
<ED>Influenzavirus; Influenza A virus; Influenza B virus; Influenza A; Influenza B; Child; Adult; Severe; Critically ill; Acute; Respiratory tract; Severe acute respiratory syndrome; Treatment; Diagnosis</ED>
<EG>Orthomyxoviridae; Virus; Influenzavirus A; Influenzavirus B; Viral disease; Infection; Human; Respiratory disease; Lung disease; Respiratory system</EG>
<SD>Influenzavirus; Influenza A virus; Influenza B virus; Gripe A; Gripe B; Niño; Adulto; Grave; Enfermo estado grave; Agudo; Vía respiratoria; Síndrome respiratorio agudo severo; Tratamiento; Diagnóstico</SD>
<LO>INIST-17422.354000113820670180</LO>
<ID>04-0484135</ID>
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New point of care test is highly specific but less sensitive for influenza virus A and B in children and adults

New point of care test is highly specific but less sensitive for influenza virus A and B in children and adults

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