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International research networks in viral structural proteomics : Again, lessons from SARS

Identifieur interne : 000277 ( PascalFrancis/Corpus ); précédent : 000276; suivant : 000278

International research networks in viral structural proteomics : Again, lessons from SARS

Auteurs : Bruno Canard ; Jeremiah S. Joseph ; Peter Kuhn

Source :

RBID : Pascal:08-0296266

Descripteurs français

English descriptors

Abstract

Emerging and re-emerging pathogens and bioterror threats require an organized and coherent response from the worldwide research community to maximize available resources and competencies with the primary goals to understand the pathogen and enable intervention. In 2001, the Structural Proteomics In Europe (SPINE) project prototyped the pan-viral structural genomic approach, and the Severe Acute Respiratory Syndrome (SARS) outbreak in 2003 accelerated the concept of structural characterization of all proteins from a viral proteome and the interaction with their host partners. Following that approach, in 2004 the center for Functional and Structural Proteomics for SARS-CoV related proteins was initiated as part of the US NIH NIAID proteomics resource centers. Across worldwide efforts in Asia, Europe and America, the international research teams working on SARS-CoV have now determined experimental structural information for 45% of the SARS-CoV proteins and 53% of all its soluble proteins. This data is fully available to the scientific community and is providing an unprecedented level of insight to this class of RNA viruses. The efforts and results by the international scientific community to the SARS outbreak are serving as an example and roadmap of a rapid response using modem research methods.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
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A02 01      @0 ARSRDR
A03   1    @0 Antivir. res.
A05       @2 78
A06       @2 1
A08 01  1  ENG  @1 International research networks in viral structural proteomics : Again, lessons from SARS
A09 01  1  ENG  @1 Treatment of highly pathogenic RNA viral infections
A11 01  1    @1 CANARD (Bruno)
A11 02  1    @1 JOSEPH (Jeremiah S.)
A11 03  1    @1 KUHN (Peter)
A12 01  1    @1 BRAY (Mike) @9 limin.
A12 02  1    @1 NEYTS (Johan) @9 limin.
A14 01      @1 Architecture Et Fonction Des Macromolécules Biologiques UMR 6098, CNRS, Universités Aix-Marseille I & II, Case 932, 163 Avenue de Luminy @2 13288 Marseille @3 FRA @Z 1 aut.
A14 02      @1 Department of Cell Biology, The Scripps Research Institute, 10550 N Torrey Pines Road, CB265 @2 La Jolla, CA 92037 @3 USA @Z 2 aut. @Z 3 aut.
A15 01      @1 Integrated Research Facility, National Institute of Allergy and Infectious Diseases, National Institutes of Health @2 Bethesda, MD @3 USA @Z 1 aut.
A15 02      @1 Rega Institute for Medical Research, Catholic University Leuven @2 Leuven @3 BEL @Z 2 aut.
A20       @1 47-50
A21       @1 2008
A23 01      @0 ENG
A43 01      @1 INIST @2 18839 @5 354000172642930040
A44       @0 0000 @1 © 2008 INIST-CNRS. All rights reserved.
A45       @0 3/4 p.
A47 01  1    @0 08-0296266
A60       @1 P
A61       @0 A
A64 01  1    @0 Antiviral research
A66 01      @0 NLD
C01 01    ENG  @0 Emerging and re-emerging pathogens and bioterror threats require an organized and coherent response from the worldwide research community to maximize available resources and competencies with the primary goals to understand the pathogen and enable intervention. In 2001, the Structural Proteomics In Europe (SPINE) project prototyped the pan-viral structural genomic approach, and the Severe Acute Respiratory Syndrome (SARS) outbreak in 2003 accelerated the concept of structural characterization of all proteins from a viral proteome and the interaction with their host partners. Following that approach, in 2004 the center for Functional and Structural Proteomics for SARS-CoV related proteins was initiated as part of the US NIH NIAID proteomics resource centers. Across worldwide efforts in Asia, Europe and America, the international research teams working on SARS-CoV have now determined experimental structural information for 45% of the SARS-CoV proteins and 53% of all its soluble proteins. This data is fully available to the scientific community and is providing an unprecedented level of insight to this class of RNA viruses. The efforts and results by the international scientific community to the SARS outbreak are serving as an example and roadmap of a rapid response using modem research methods.
C02 01  X    @0 002B02S05
C02 02  X    @0 002B05C02C
C03 01  X  FRE  @0 Réseau international @5 01
C03 01  X  ENG  @0 International network @5 01
C03 01  X  SPA  @0 Red internacional @5 01
C03 02  X  FRE  @0 Protéomique @5 02
C03 02  X  ENG  @0 Proteomics @5 02
C03 02  X  SPA  @0 Proteómica @5 02
C03 03  X  FRE  @0 Relation structure activité @5 03
C03 03  X  ENG  @0 Structure activity relation @5 03
C03 03  X  SPA  @0 Relación estructura actividad @5 03
C03 04  X  FRE  @0 Syndrome respiratoire aigu sévère @2 NM @5 04
C03 04  X  ENG  @0 Severe acute respiratory syndrome @2 NM @5 04
C03 04  X  SPA  @0 Síndrome respiratorio agudo severo @2 NM @5 04
C03 05  X  FRE  @0 Virus syndrome respiratoire aigu sévère @2 NW @5 05
C03 05  X  ENG  @0 Severe acute respiratory syndrome virus @2 NW @5 05
C03 05  X  SPA  @0 Severe acute respiratory syndrome virus @2 NW @5 05
C03 06  X  FRE  @0 Génomique @5 07
C03 06  X  ENG  @0 Genomics @5 07
C03 06  X  SPA  @0 Genómica @5 07
C03 07  X  FRE  @0 Virus à ARN @5 08
C03 07  X  ENG  @0 RNA virus @5 08
C03 07  X  SPA  @0 Virus con RNA @5 08
C03 08  X  FRE  @0 Recherche et développement @5 09
C03 08  X  ENG  @0 Research and development @5 09
C03 08  X  SPA  @0 Investigación desarrollo @5 09
C03 09  X  FRE  @0 Antiviral @5 10
C03 09  X  ENG  @0 Antiviral @5 10
C03 09  X  SPA  @0 Antiviral @5 10
C03 10  X  FRE  @0 Projet Vizier @4 INC @5 86
C07 01  X  FRE  @0 Virose
C07 01  X  ENG  @0 Viral disease
C07 01  X  SPA  @0 Virosis
C07 02  X  FRE  @0 Infection
C07 02  X  ENG  @0 Infection
C07 02  X  SPA  @0 Infección
C07 03  X  FRE  @0 Coronavirus @2 NW
C07 03  X  ENG  @0 Coronavirus @2 NW
C07 03  X  SPA  @0 Coronavirus @2 NW
C07 04  X  FRE  @0 Coronaviridae @2 NW
C07 04  X  ENG  @0 Coronaviridae @2 NW
C07 04  X  SPA  @0 Coronaviridae @2 NW
C07 05  X  FRE  @0 Nidovirales @2 NW
C07 05  X  ENG  @0 Nidovirales @2 NW
C07 05  X  SPA  @0 Nidovirales @2 NW
C07 06  X  FRE  @0 Virus @2 NW
C07 06  X  ENG  @0 Virus @2 NW
C07 06  X  SPA  @0 Virus @2 NW
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C07 07  X  SPA  @0 Aparato respiratorio patología @5 37
C07 08  X  FRE  @0 Pathologie des poumons @5 38
C07 08  X  ENG  @0 Lung disease @5 38
C07 08  X  SPA  @0 Pulmón patología @5 38
N21       @1 189

Format Inist (serveur)

NO : PASCAL 08-0296266 INIST
ET : International research networks in viral structural proteomics : Again, lessons from SARS
AU : CANARD (Bruno); JOSEPH (Jeremiah S.); KUHN (Peter); BRAY (Mike); NEYTS (Johan)
AF : Architecture Et Fonction Des Macromolécules Biologiques UMR 6098, CNRS, Universités Aix-Marseille I & II, Case 932, 163 Avenue de Luminy/13288 Marseille/France (1 aut.); Department of Cell Biology, The Scripps Research Institute, 10550 N Torrey Pines Road, CB265/La Jolla, CA 92037/Etats-Unis (2 aut., 3 aut.); Integrated Research Facility, National Institute of Allergy and Infectious Diseases, National Institutes of Health/Bethesda, MD/Etats-Unis (1 aut.); Rega Institute for Medical Research, Catholic University Leuven/Leuven/Belgique (2 aut.)
DT : Publication en série; Niveau analytique
SO : Antiviral research; ISSN 0166-3542; Coden ARSRDR; Pays-Bas; Da. 2008; Vol. 78; No. 1; Pp. 47-50; Bibl. 3/4 p.
LA : Anglais
EA : Emerging and re-emerging pathogens and bioterror threats require an organized and coherent response from the worldwide research community to maximize available resources and competencies with the primary goals to understand the pathogen and enable intervention. In 2001, the Structural Proteomics In Europe (SPINE) project prototyped the pan-viral structural genomic approach, and the Severe Acute Respiratory Syndrome (SARS) outbreak in 2003 accelerated the concept of structural characterization of all proteins from a viral proteome and the interaction with their host partners. Following that approach, in 2004 the center for Functional and Structural Proteomics for SARS-CoV related proteins was initiated as part of the US NIH NIAID proteomics resource centers. Across worldwide efforts in Asia, Europe and America, the international research teams working on SARS-CoV have now determined experimental structural information for 45% of the SARS-CoV proteins and 53% of all its soluble proteins. This data is fully available to the scientific community and is providing an unprecedented level of insight to this class of RNA viruses. The efforts and results by the international scientific community to the SARS outbreak are serving as an example and roadmap of a rapid response using modem research methods.
CC : 002B02S05; 002B05C02C
FD : Réseau international; Protéomique; Relation structure activité; Syndrome respiratoire aigu sévère; Virus syndrome respiratoire aigu sévère; Génomique; Virus à ARN; Recherche et développement; Antiviral; Projet Vizier
FG : Virose; Infection; Coronavirus; Coronaviridae; Nidovirales; Virus; Pathologie de l'appareil respiratoire; Pathologie des poumons
ED : International network; Proteomics; Structure activity relation; Severe acute respiratory syndrome; Severe acute respiratory syndrome virus; Genomics; RNA virus; Research and development; Antiviral
EG : Viral disease; Infection; Coronavirus; Coronaviridae; Nidovirales; Virus; Respiratory disease; Lung disease
SD : Red internacional; Proteómica; Relación estructura actividad; Síndrome respiratorio agudo severo; Severe acute respiratory syndrome virus; Genómica; Virus con RNA; Investigación desarrollo; Antiviral
LO : INIST-18839.354000172642930040
ID : 08-0296266

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Pascal:08-0296266

Le document en format XML

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<s5>09</s5>
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<s5>86</s5>
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<s2>NW</s2>
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<s0>Nidovirales</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="05" i2="X" l="ENG">
<s0>Nidovirales</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="05" i2="X" l="SPA">
<s0>Nidovirales</s0>
<s2>NW</s2>
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<fC07 i1="06" i2="X" l="FRE">
<s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="06" i2="X" l="ENG">
<s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="06" i2="X" l="SPA">
<s0>Virus</s0>
<s2>NW</s2>
</fC07>
<fC07 i1="07" i2="X" l="FRE">
<s0>Pathologie de l'appareil respiratoire</s0>
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<s0>Respiratory disease</s0>
<s5>37</s5>
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<s0>Aparato respiratorio patología</s0>
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<fC07 i1="08" i2="X" l="SPA">
<s0>Pulmón patología</s0>
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<server>
<NO>PASCAL 08-0296266 INIST</NO>
<ET>International research networks in viral structural proteomics : Again, lessons from SARS</ET>
<AU>CANARD (Bruno); JOSEPH (Jeremiah S.); KUHN (Peter); BRAY (Mike); NEYTS (Johan)</AU>
<AF>Architecture Et Fonction Des Macromolécules Biologiques UMR 6098, CNRS, Universités Aix-Marseille I & II, Case 932, 163 Avenue de Luminy/13288 Marseille/France (1 aut.); Department of Cell Biology, The Scripps Research Institute, 10550 N Torrey Pines Road, CB265/La Jolla, CA 92037/Etats-Unis (2 aut., 3 aut.); Integrated Research Facility, National Institute of Allergy and Infectious Diseases, National Institutes of Health/Bethesda, MD/Etats-Unis (1 aut.); Rega Institute for Medical Research, Catholic University Leuven/Leuven/Belgique (2 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Antiviral research; ISSN 0166-3542; Coden ARSRDR; Pays-Bas; Da. 2008; Vol. 78; No. 1; Pp. 47-50; Bibl. 3/4 p.</SO>
<LA>Anglais</LA>
<EA>Emerging and re-emerging pathogens and bioterror threats require an organized and coherent response from the worldwide research community to maximize available resources and competencies with the primary goals to understand the pathogen and enable intervention. In 2001, the Structural Proteomics In Europe (SPINE) project prototyped the pan-viral structural genomic approach, and the Severe Acute Respiratory Syndrome (SARS) outbreak in 2003 accelerated the concept of structural characterization of all proteins from a viral proteome and the interaction with their host partners. Following that approach, in 2004 the center for Functional and Structural Proteomics for SARS-CoV related proteins was initiated as part of the US NIH NIAID proteomics resource centers. Across worldwide efforts in Asia, Europe and America, the international research teams working on SARS-CoV have now determined experimental structural information for 45% of the SARS-CoV proteins and 53% of all its soluble proteins. This data is fully available to the scientific community and is providing an unprecedented level of insight to this class of RNA viruses. The efforts and results by the international scientific community to the SARS outbreak are serving as an example and roadmap of a rapid response using modem research methods.</EA>
<CC>002B02S05; 002B05C02C</CC>
<FD>Réseau international; Protéomique; Relation structure activité; Syndrome respiratoire aigu sévère; Virus syndrome respiratoire aigu sévère; Génomique; Virus à ARN; Recherche et développement; Antiviral; Projet Vizier</FD>
<FG>Virose; Infection; Coronavirus; Coronaviridae; Nidovirales; Virus; Pathologie de l'appareil respiratoire; Pathologie des poumons</FG>
<ED>International network; Proteomics; Structure activity relation; Severe acute respiratory syndrome; Severe acute respiratory syndrome virus; Genomics; RNA virus; Research and development; Antiviral</ED>
<EG>Viral disease; Infection; Coronavirus; Coronaviridae; Nidovirales; Virus; Respiratory disease; Lung disease</EG>
<SD>Red internacional; Proteómica; Relación estructura actividad; Síndrome respiratorio agudo severo; Severe acute respiratory syndrome virus; Genómica; Virus con RNA; Investigación desarrollo; Antiviral</SD>
<LO>INIST-18839.354000172642930040</LO>
<ID>08-0296266</ID>
</server>
</inist>
</record>

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